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Mitofusin 2 (MFN2) (NM_014874) Human Untagged Clone
CAT＃: SC114726
MFN2 (untagged)-Human mitofusin 2 (MFN2), nuclear gene encoding mitochondrial protein, transcript variant 1
CNY 5,552.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CMT2A; CMT2A2; CMT2A2A; CMT2A2B; CPRP1; HMSN6A; HSG; MARF |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_014874, the custom clone sequence may differ by one or more nucleotides
ATGTCCCTGCTCTTCTCTCGATGCAACTCTATCGTCACAGTCAAGAAAAATAAGAGACACATGGCTGAGG TGAATGCATCCCCACTTAAGCACTTTGTCACTGCCAAGAAGAAGATCAATGGCATTTTTGAGCAGCTGGG GGCCTACATCCAGGAGAGCGCCACCTTCCTTGAAGACACGTACAGGAATGCAGAACTGGACCCCGTTACC ACAGAAGAACAGGTTCTGGACGTCAAAGGTTACCTATCCAAAGTGAGAGGCATCAGTGAGGTGCTGGCTC GGAGGCACATGAAAGTGGCTTTTTTTGGCCGGACGAGCAATGGGAAGAGCACCGTGATCAATGCCATGCT CTGGGACAAAGTTCTGCCCTCTGGGATTGGCCACACCACCAATTGCTTCCTGCGGGTAGAGGGCACAGAT GGCCATGAGGCCTTTCTCCTTACCGAGGGCTCAGAGGAAAAGAGGAGTGCCAAGACTGTGAACCAGCTGG CCCATGCCCTCCACCAGGACAAGCAGCTCCATGCCGGCAGCCTAGTGAGTGTGATGTGGCCCAACTCTAA GTGCCCACTTCTGAAGGATGACCTCGTTTTGATGGACAGCCCTGGTATTGATGTCACCACAGAGCTGGAC AGCTGGATTGACAAGTTTTGTCTGGATGCTGATGTGTTTGTGCTGGTGGCCAACTCAGAGTCCACCCTGA TGCAGACGGAAAAGCACTTCTTCCACAAGGTGAGTGAGCGTCTCTCCCGGCCAAACATCTTCATCCTGAA CAACCGCTGGGATGCATCTGCCTCAGAGCCCGAGTACATGGAGGAGGTGCGGCGGCAGCACATGGAGCGT TGTACCAGCTTCCTGGTGGATGAGCTGGGCGTGGTGGATCGATCCCAGGCCGGGGACCGCATCTTCTTTG TGTCTGCTAAGGAGGTGCTCAACGCCAGGATTCAGAAAGCCCAGGGCATGCCTGAAGGAGGGGGCGCTCT CGCAGAAGGCTTTCAAGTGAGGATGTTTGAGTTTCAGAATTTTGAGAGGAGATTTGAGGAGTGCATCTCC CAGTCTGCAGTGAAGACCAAGTTTGAGCAGCACACGGTCCGGGCCAAGCAGATTGCAGAGGCGGTTCGAC TCATCATGGACTCCCTGCACATGGCGGCTCGGGAGCAGCAGGTTTACTGCGAGGAAATGCGTGAAGAGCG GCAAGACCGACTGAAATTTATTGACAAACAGCTGGAGCTCTTGGCTCAAGACTATAAGCTGCGAATTAAG CAGATTACGGAGGAAGTGGAGAGGCAGGTGTCGACTGCAATGGCCGAGGAGATCAGGCGCCTCTCTGTAC TGGTGGACGATTACCAGATGGACTTCCACCCTTCTCCAGTAGTCCTCAAGGTTTATAAGAATGAGCTGCA CCGCCACATAGAGGAAGGACTGGGTCGAAACATGTCTGACCGCTGCTCCACGGCCATCACCAACTCCCTG CAGACCATGCAGCAGGACATGATAGATGGCTTGAAACCCCTCCTTCCTGTGTCTGTGCGGAGTCAGATAG ACATGCTGGTCCCACGCCAGTGCTTCTCCCTCAACTATGACCTAAACTGTGACAAGCTGTGTGCTGACTT CCAGGAAGACATTGAGTTCCATTTCTCTCTCGGATGGACCATGCTGGTGAATAGGTTCCTGGGCCCCAAG AACAGCCGTCGGGCCTTGATGGGCTACAATGACCAGGTCCAGCGTCCCATCCCTCTGACGCCAGCCAACC CCAGCATGCCCCCACTGCCACAGGGCTCGCTCACCCAGGAGGAGTTCATGGTTTCCATGGTTACCGGCCT GGCCTCCTTGACATCCAGGACCTCCATGGGCATTCTTGTTGTTGGAGGAGTGGTGTGGAAGGCAGTGGGC TGGCGGCTCATTGCCCTCTCCTTTGGGCTCTATGGCCTCCTCTACGTCTATGAGCGTCTGACCTGGACCA CCAAGGCCAAGGAGAGGGCCTTCAAGCGCCAGTTTGTGGAGCATGCCAGCGAGAAGCTGCAGCTTGTCAT CAGCTACACTGGCTCCAACTGCAGCCACCAAGTCCAGCAGGAACTGTCTGGGACCTTTGCTCATCTGTGT CAGCAAGTTGACGTCACCCGGGAGAACCTGGAGCAGGAAATTGCCGCCATGAACAAGAAAATTGAGGTTC TTGACTCACTTCAGAGCAAAGCAAAGCTGCTCAGGAATAAAGCCGGTTGGTTGGACAGTGAGCTCAACAT GTTCACACACCAGTACCTGCAGCCCAGCAGATAG >OriGene 5' read for NM_014874 unedited
NGGTTCGAATTTTGGTATACGAACTCACTATAGGGCGGCCGCGATTCGGCACCAGGGGAG GTGAAGTCAGGACTGGTGGAGTCAACACAGTCAATCAATAGCCAACCTCAACCTGAGACA GGACAGAAGAGAACTCAGAATCTTTTTGTCTTTTGGACTTCAGCCATGTCCATGATGCCT ACCCTGTGAAGATCTCTCACCATCCAAAAAACGCAATGTCCCTGCTCTTCTCTCGATGCA ACTCTATCGTCACAGTCAAGAAAAATAAGAGACACATGGCTGAGGTGAATGCATCCCCAC TTAAGCACTTTGTCACTGCCAAGAAGAAGATCAATGGCATTTTTGAGCAGCTGGGGGCCT ACATCCAGGAGAGCGCCACCTTCCTTGAAGACACGTACAGGAATGCAGAACTGGACCCCG TTACCACAGAAGAACAGGTTCTGGACGTCAAAGGTTACCTATCCAAAGTGAGAGGCATCA GTGAGGTGCTGGCTCGGAGGCACATGAAAGTGGCTTTTTTTGGCCGGACGAGCAATGGGA AGAGCACCGTGATCAATGCCATGCTCTGGGACAAAGTTCTGCCCTCTGGGATTGGCCACA CCACCAATTGCTTCCTGCGGGTAGAGGGCACAGATGGCCATGAGGCCTTTCTCCTTACCG AGGGCTCAGAGGAAAAGAGGAGTGCCAAGACTGTGAACCAGCTGGCCCATGCCCTCCACC AGGACAAGCAGCTCCATGCCGGCAGCCTAGTGAGTGTGATGTGGCCCAACTCTAAGTGCC CACTTCTGAAGGATGACCTCGTTTTGATGGACAGNCCCTGGTATTGATGTCACCACAGAG CTGGACAGCTGGATTGACAAGTNTTGTCTGATGCTGATGNGTTTGTGCTGGTGGCCACTC AGAGTCANCCCTGAGC >OriGene 3' read for NM_014874 unedited
CTATGGACCCGCGGCCGCAATCTAGNAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCACCAAGAGGATTCCCACCTGGGTTTTTTT TTATTTCCCAATTTTTGGACCATGGATCCGGGGGTACCTCAGCCAAATCCTTCCCCTTAA ATCCTTCAAAAAAACCTCCTTGGGTCACCCCGTTTGGCCCCCCACCAAAGGACCTTAAAA CCACCATGGCCCCCACCTTAAAAGGGCTTTGGGCCATCCTTTTTTAAAAAGGGGCCTCCC CCTCAGGGGAAAAAATTAAATTTTCCGTTTGGAAAAACCCCAAAATTTTTTTCTTTCCCC GGGGGCTCCTTTAAAAAAAAATTCTTGTTCCCCCTAAAAAATTTTTTTTTTTCAAAAAAA CCCCAAATTCCTTGGAAATGGGGGAACAGGAATTTCCCCTAACATGCTGGAAAGGGGCCC TGGTCCTTTAGGGCCCCCCACCCCCCGGGACACCCCCCCCCCACCTTGCCCCCCGGCAAG ACTCCCACCCTTCCCCCCCAACCCAAGGCCACACGGGGGGCTCTTAACCCCCCGCGTTTC CCCCAACGGCCCACCACCCTGATTGCGGCGGCTCCCACATGGCGTGAGGGGGCGTTCCCA TCCCCCCCTCAACCAGCCCATCCGGCGCCTGGCCCNCCCCCCCCCCACACAGCGGCGCCC CCTTTCTGACCGATGCCATCTTCNCGCACCGTCACGCACTTACGCGTACACTGTCTCTAT CATCATTATTTTCATACGCATTCCTNGACCAATCCTCCCCNTTTCCCCCCCCGCTTCTCC GGCCCGCCACCTCTGTTTCCCCCCACGCGCCACCCGTATATTTACACCCCCGCACCCCCC ACGCGTTCCTCTCTCCCCNNNNCNACCCTACCTCCCCGCCGCCTCCGCCCCCCATTTGGC CCCGCACCACCCTCACTTACTNTCTCCACTTACTCACCCCCGTACAACCCACTCTCCCCA CTCCCCCCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_014874 |
| Insert Size | 3810 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_014874.2, NP_055689.1 |
| RefSeq Size | 4546 bp |
| RefSeq ORF | 2274 bp |
| Locus ID | 9927 |
| UniProt ID | O95140 |
| Domains | fzo_mitofusin |
| Protein Families | Transmembrane |
| Gene Summary | This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Cystathionine beta synthase regulates mitochondrial dynamics and function in endothelial cells
,Rao, G;Murphy, B;Dey, A;Dwivedi, SKD;Zhang, Y;Roy, RV;Chakraborty, P;Bhattacharya, R;Mukherjee, P;,
FASEB J.
,PubMed ID 32463541
[MFN2]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202218 | MFN2 (Myc-DDK-tagged)-Human mitofusin 2 (MFN2), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 5,544.00 |
|
| RC202218L1 | Lenti ORF clone of Human mitofusin 2 (MFN2), nuclear gene encoding mitochondrial protein, transcript variant 1, Myc-DDK-tagged |
CNY 7,944.00 |
|
| RC202218L2 | Lenti ORF clone of Human mitofusin 2 (MFN2), nuclear gene encoding mitochondrial protein, transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC202218L3 | Lenti ORF clone of Human mitofusin 2 (MFN2), nuclear gene encoding mitochondrial protein, transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC202218L4 | Lenti ORF clone of Human mitofusin 2 (MFN2), nuclear gene encoding mitochondrial protein, transcript variant 1, mGFP tagged |
CNY 7,944.00 |
|
| RG202218 | MFN2 (tGFP-tagged) - Human mitofusin 2 (MFN2), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 7,144.00 |
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