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RAP1B (NM_015646) Human Untagged Clone
CAT＃: SC114605
RAP1B (untagged)-Human RAP1B, member of RAS oncogene family (RAP1B), transcript variant 1
CNY 2,400.00
CNY 2,950.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | K-REV; RAL1B |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC114605 sequence for NM_015646 edited (data generated by NextGen Sequencing)
ATGCGTGAGTATAAGCTAGTCGTTCTTGGCTCAGGAGGCGTTGGAAAGTCTGCTTTGACT GTACAATTTGTTCAAGGAATTTTTGTAGAAAAATACGATCCTACGATAGAAGATTCTTAT AGAAAGCAAGTTGAAGTAGATGCACAACAGTGTATGCTTGAAATCTTGGATACTGCAGGA ACGGAGCAATTTACAGCAATGAGGGATTTATACATGAAAAATGGACAAGGATTTGCATTA GTTTATTCCATCACAGCACAGTCCACATTTAACGATTTACAAGACCTGAGAGAACAGATT CTTCGAGTTAAAGACACTGATGATGTTCCAATGATTCTTGTTGGTAATAAGTGTGACTTG GAAGATGAAAGAGTTGTAGGGAAGGAACAAGGTCAAAATCTAGCAAGACAATGGAACAAC TGTGCATTCTTAGAATCTTCTGCAAAATCAAAAATAAATGTTAATGAGATCTTTTATGAC CTAGTGCGGCAAATTAACAGAAAAACTCCAGTGCCTGGGAAGGCTCGCAAAAAGTCATCA TGTCAGCTGCTTTAA Clone variation with respect to NM_015646.4 >OriGene 5' read for NM_015646 unedited
GTCAGAATTTGTATACGACTCCTATAGGGCGGCCGCGATTCGGCACGAGGCCAGATTCAG GCGTGTAAACCAGCCGGAGCGGCGCGGCAGCGGCAGGACCGCCGTGGCGCCTAGAGTAGC GACCCGGGGGGAGCGCGGGGCGACGCTGGCTGCAGGGACCCGGTGACAGCGTGAGAGGTA CTAGGTTTTGACAAGCTTGCATCATGCGTGAGTATAAGCTAGTCGTTCTTGGCTCAGGAG GCGTTGGAAAGTCTGCTTTGACTGTACAATTTGTTCAAGGAATTTTTGTAGAAAAATACG ATCCTACGATAGAAGATTCTTATAGAAAGCAAGTTGAAGTAGATGCACAACAGTGTATGC TTGAAATCTTGGATACTGCAGGAACGGAGCAATTTACAGCAATGAGGGATTTATACATGA AAAATGGACAAGGATTTGCATTAGTTTATTCCATCACAGCACAGTCCACATTTAACGATT TACAAGACCTGAGAGAACAGATTCTTCGAGTTAAAGACACTGATGATGTTCCAATGATTC TTGTTGGTAATAAGTGTGACTTGGAAGATGAAAGAGTTGTAGGGAAGGAACAAGGTCAAA ATCTAGCAAGACAATGGAACAACTGTGCATTCTTAGAATCTTCTGCAAAATCAAAAATAA ATGTTAATGAGATCTTTTATGACCTAGTGCGGCACATTAACAGANAAACTCCAGTGCCTG GGAAGGCTCGCNAAAAGTCATCATGTCAGCTGCTTTAATATACTACATGCATTGTAGCTC TGAGCCAGTTCTGAAAGACTGTTGCCCCATTCACAGTGCCAGCATTCCAACTTTGTTAAA CCTACCAACATCCTAAATGGACTCTCCCTGTGGTGGTACCCTTTAGGAGGCGGATGAAAG CTACATTATCAGTTTGCACATTCTAAT >OriGene 3' read for NM_015646 unedited
ACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCTTTTTTTTTTTTTTTT TTGGCAAGTAATTATAATGCAAGCCCTTGCATGGCAATCCAAATTTATTGAACTACTGAT GCTAAGTTATACAAAATTGCACCACTTTAATTAAGGCTTTTAGTTTACATTTGGCCACCT CAAAGTAGTTGTAACATTAGGTTGGTCAATTTAAATACTGGGGCTCCCTGTTGGATAGAC ACACAATCTTTACATCCAAACATTAATGCATACAAAGCAACAAGGCATTGTTAAATAAAA CAGCAATAGTTACTGCAAATTAGGCCTTGTGACCAATTACATATGATTAAAATTACTTCC CACATTCACATCCACAGTACTCGTCCACCATTTAACATCTCAACCAAAACGTTACACATG TGAAACAATCACTAACAGGCAAAAATACTAAACCTGTATATTTGGTATTGCAAATACACT TATGCATGAGCAAGCAAGGGATTCACAGTGAGAATCTACAGCTGCAGAAGCCTGAAAATG ATTTACAAAAATTGTTAAATCATTAAAAAATTGTTTGAAAATATACACTTCTTGTTGTAG ACCCCCACTGTACACACGACTATAAACATTGTTCCCTATGTAAACAAAAAAAGGAAACAT ATAATAAGAGATTTGAAAAGTCTGGACATTTCCTTTCCAACAGATATTAAAGGCAACGTC TTTAATCTAAGACATTATACTGAAAGGACTATCATGTTTTTAAGACCAGATCACCCGTCT CACAGGTTTTTTTAAAATTAAAAAAACTTATAAGCTGTGGTAATCAAAGCGCTTATTTTT GACAATAATAATGACCTTGAATTTCTTAAAAAAAATACAATAGCCTACAGTTTTAAAGAA CGAAGTTTCCTGGATAGTCTTATAGGGAGCCTTTGCACTTTCTTTATTATGCAAC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_015646 |
| Insert Size | 2140 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_015646.4, NP_056461.1 |
| RefSeq Size | 2126 bp |
| RefSeq ORF | 555 bp |
| Locus ID | 5908 |
| UniProt ID | P61224 |
| Domains | ras, RAN, RAS, RHO, RAB |
| Protein Families | Druggable Genome |
| Protein Pathways | Chemokine signaling pathway, Focal adhesion, Leukocyte transendothelial migration, Long-term potentiation, MAPK signaling pathway, Neurotrophin signaling pathway, Renal cell carcinoma |
| Gene Summary | This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9. [provided by RefSeq, Oct 2011] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Variants 1 and 2 encode the same isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Amplification of CRKL Induces Transformation and Epidermal Growth Factor Receptor Inhibitor Resistance in Human Non–Small Cell Lung Cancers
,Hihu Wing Cheung, Jinyan Du, Jesse S. Boehm, Frank He, Barbara A. Weir, Xiaoxing Wang, Mohit Butaney, Lecia V. Sequist, Biao Luo, Jeffrey A. Engelman, David E. Root, Matthew Meyerson, Todd R. Golub, Pasi A. Jänne, and William C. Hahn,
Cancer Discovery, Dec 2011; 1: 608 - 625.
[RAP1B]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC221678 | RAP1B (Myc-DDK-tagged)-Human RAP1B, member of RAS oncogene family (RAP1B), transcript variant 1 |
CNY 2,400.00 |
|
| RC221678L1 | Lenti ORF clone of Human RAP1B, member of RAS oncogene family (RAP1B), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC221678L2 | Lenti ORF clone of Human RAP1B, member of RAS oncogene family (RAP1B), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC221678L3 | Lenti ORF clone of Human RAP1B, member of RAS oncogene family (RAP1B), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC221678L4 | Lenti ORF clone of Human RAP1B, member of RAS oncogene family (RAP1B), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG221678 | RAP1B (tGFP-tagged) - Human RAP1B, member of RAS oncogene family (RAP1B), transcript variant 1 |
CNY 4,370.00 |
