United States
Germany
Japan
United Kingdom
China
JPT1 (NM_016185) Human Untagged Clone
CAT＃: SC114413
HN1 (untagged)-Human hematological and neurological expressed 1 (HN1), transcript variant 1
CNY 1,200.00
CNY 3,990.00
Product images
CNY 6,281.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARM2; HN1; HN1A |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC114413 sequence for NM_016185 edited (data generated by NextGen Sequencing)
ATGACCACAACCACCACCTTCAAGGGAGTCGACCCCAACAGCAGGAATAGCTCCCGAGTT TTGCGGCCTCCAGGTGGTGGATCCAATTTTTCATTAGGTTTTGATGAACCAACAGAACAA CCTGTGAGGAAGAACAAAATGGCCTCTAATATCTTTGGGACACCTGAAGAAAATCAAGCT TCTTGGGCCAAGTCAGCAGGTGCCAAGTCTAGTGGTGGCAGGGAAGACTTGGAGTCATCT GGACTGCAGAGAAGGAACTCCTCTGAAGCAAGCTCCGGAGACTTCTTAGATCTGAAGGGA GAAGGTGATATTCATGAAAATGTGGACACAGACTTGCCAGGCAGCCTGGGGCAGAGTGAA GAGAAGCCCGTGCCTGCTGCGCCTGTGCCCAGCCCGGTGGCCCCGGCCCCAGTGCCATCC AGAAGAAATCCCCCTGGCGGCAAGTCCAGCCTCGTCTTGGGTTAG Clone variation with respect to NM_016185.2 >OriGene 5' read for NM_016185 unedited
TTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGTGCAGCGGTGGTCGGC TGTTGGGTGTGGAGTTTCCCAGCGCCCCTCGGGTCCGACCCTTTGAGCGTTCTGCTCCGG CGCCAGCCTACCTCGCTCCTCGGCGCCATGACCACAACCACCACCTTCAAGGGAGTCGAC CCCAACAGCAGGAATAGCTCCCGAGTTTTGCGGCCTCCAGGTGGTGGATCCAATTTTTCA TTAGGTTTTGATGAACCAACAGAACAACCTGTGAGGAAGAACAAAATGGCCTCTAATATC TTTGGGACACCTGAAGAAAATCAAGCTTCTTGGGCCAAGTCAGCAGGTGCCAAGTCTAGT GGTGGCAGGGAAGACTTGGAGTCATCTGGACTGCAGAGAAGGAACTCCTCTGAAGCAAGC TCCGGAGACTTCTTAGATCTGAAGGGAGAAGGTGATATTCATGAAAATGTGGACACAGAC TTGCCAGGCAGCCTGGGGCAGAGTGAAGAGAAGCCCGTGCCTGCTGCGCCTGTGCCCAGC CCGGTGGCCCCGGCCCCAGTGCCATCCAGAAGAAATCCCCCTGGCGGCAAGTCCAGCCTC GTCTTGGGTTAGCTCTGACTGTCCTGAACGCTGTCGTTCTGTCTGTTTCCTCCATGCTTG TGAACTGCACAACTTGAGCCTGACTGTACATCTCTTGGATTTGTTTCATTAAAAGAAGCA CTTTATGTACTGCTGGCTTTTTTTTTTTTTCTTTGAAGACAGGTTTCTCTCTGTCTTGAC TCTTGGGTCTGTGGGCCATGGCATGAGTGTTTTCTAGTATTAGATTGGAGGGAAAGCTTG TGACCCTTANTACTGTGGTTTTAAAGAGAAATATNTGGCTTCCAGATGTGTTAAA >OriGene 3' read for NM_016185 unedited
GGCACGCAATCTAGNATCGAGTTTTTTTTTTTTTTTTTTAAAAGTGGATATTGTTTACTT GAAGCAACAGTCCAGGATTGTGAAGTACAACACATTTTAAGGATGAGACTTTCCTTTCAT GGTCAAGCACCAGCATCATGCACACAGCATCAGGTTATTTAAAACAACACGCCTGTGGGA CCCCGTTCCTGGAGGAAGACCCGCTTCAGTGTGATTGCCTCCCTTGCTTCACTGCTTTTA GTTCCAGGCAGTTTCATTGTACATCCAAGCCTTCCTCTGCGTGAGAGCAAAGGCTTTGCT CATCAGCCAGCCAGTCTTGTTACTATCTGGCTACTTTTTAAGGTTAAAAAATAAAAGGCA GTTTCTTTGCTTTGCAGGCGGCAAGGCAGGAGGCGCAGGCCTCTTCATTGTTCACATGTC ACAGGAGGAGGCTCTGAGCAAAGGCCACTGGCAAGTTAGGGCAACACCAAGAAGGCTCTG CGGAGAGACTCCCTGTGGGTTGGGGCCTGGCAGGAACGGTGCCTGTGGACTGTTTATGGT CTGTACAGTTGAGGCTTGGTAAACCCAAGTAAAGTGTTAAAAACCTCAGTACAAAAGATC CTCTAACACATCTGGGAACCAAATTATTTCTTCTTAAAACACAGTCCTAAGTGTCACAAA GCTTTTCCTCCATTCTACTACTNAGAAACACTCATGCCATGGCCCACAGACCCCAGAAGT CAAGACAGAGAGAACCCGTTCTTCAAAAGAAAAAAAAAAGACAGCAGTCCATAAGGGCTT TCTTTTATGAAACAAATCCAAAGTATGTCCGTCGGCCTAAGTTGGGCACTTCACAACCTG AAGGAACAGAAGTACGAACAGCGTCAGGACAGTCAAGTTACCCAAACAAGTTGACTTGCC GCAGGGGAATCTTTCTGTAGGCTGTGCCCGGGCCACCGGTTGGCCAAGCCCCCAGGCAGG CT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_016185 |
| Insert Size | 1530 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_016185.2, NP_057269.1 |
| RefSeq Size | 1602 bp |
| RefSeq ORF | 465 bp |
| Locus ID | 51155 |
| UniProt ID | Q9UK76 |
| Gene Summary | Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) contains an alternate exon in the 3' coding region, resulting in a frameshift and an early stop codon, compared to variant 2. It encodes isoform 1, which is shorter and has a distinct C-terminus, compared to isoform 2. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC221865 | HN1 (Myc-DDK-tagged)-Human hematological and neurological expressed 1 (HN1), transcript variant 1 |
CNY 1,200.00 |
|
| RC221865L3 | Lenti ORF clone of Human hematological and neurological expressed 1 (HN1), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC221865L4 | Lenti ORF clone of Human hematological and neurological expressed 1 (HN1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG221865 | HN1 (tGFP-tagged) - Human hematological and neurological expressed 1 (HN1), transcript variant 1 |
CNY 2,800.00 |
