SELT (SELENOT) (NM_016275) Human Untagged Clone
CAT#: SC114373
SELT (untagged)-Human selenoprotein T (SELT) (10ug), (Note: selenocysteine protein, Internal stop codon present. see reference data summary below)
CNY 3,432.00
Product images
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Specifications
Product Data | |
Type | Human Untagged Clone |
Synonyms | SELT |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>NCBI ORF sequence for NM_016275, the custom clone sequence may differ by one or more nucleotides
ATGAGGCTTCTGCTGCTTCTCCTAGTGGCGGCGTCTGCGATGGTCCGGAGCGAGGCCTCGGCCAATCTGG GCGGCGTGCCCAGCAAGAGATTAAAGATGCAGTACGCCACGGGGCCGCTGCTCAAGTTCCAGATTTGTGT TTCCTGAGGTTATAGGCGGGTGTTTGAGGAGTACATGCGGGTTATTAGCCAGCGGTACCCAGACATCCGC ATTGAAGGAGAGAATTACCTCCCTCAACCAATATATAGACACATAGCATCTTTCCTGTCAGTCTTCAAAC TAGTATTAATAGGCTTAATAATTGTTGGCAAGGATCCTTTTGCTTTCTTTGGCATGCAAGCTCCTAGCAT CTGGCAGTGGGGCCAAGAAAATAAGGTTTATGCATGTATGATGGTTTTCTTCTTGAGCAACATGATTGAG AACCAGTGTATGTCAACAGGTGCATTTGAGATAACTTTAAATGATGTACCTGTGTGGTCTAAGCTGGAAT CTGGTCACCTTCCATCCATGCAACAACTTGTTCAAATTCTTGACAATGAAATGAAGCTCAATGTGCATAT GGATTCAATCCCACACCATCGATCATAG >OriGene 5' read for NM_016275 unedited
GGTTCACCATTTTGTATACGACTCACTATAGGGCGGCCGCGATTCGGCACGAGGGCCGAA GTGGCTGGCTCATTTAAGATGAGGCTTCTGCTGCTTCTCCTAGTGGCGGCGTCTGCGATG GTCCGGAGCGAGGCCTCGGCCAATCTGGGCGGCGTGCCCAGCAAGAGATTAAAGATGCAG TACGCCACGGGGCCGCTGCTCAAGTTCCAGATTTGTGTTTCCTGAGGTTATAGGCGGGTG TTTGAGGAGTACATGCGGGTTATTAGCCAGCGGTACCCAGACATCCGCATTGAAGGAGAG AATTACCTCCCTCAACCAATATATAGACACATAGCATCTTTCCTGTCAGTCTTCAAACTA GTATTAATAGGCTTAATAATTGTTGGCAAGGATCCTTTTGCTTTCTTTGGCATGCAAGCT CCTAGCATCTGGCAGTGGGGCCAAGAAAATAAGGTTTATGCATGTATGATGGTTTTCTTC TTGAGCAACATGATTGAGAACCAGTGTATGTCAACAGGTGCATTTGAGATAACTTTAAAT GATGTACCTGTGTGGTCTAAGCTGGAATCTGGTCACCTTCCATCCATGCAACAACTTGTT CAAATTCTTGACAATGAAATGAAGCTCAATGTGCATATGGATTCAATCCCCCACCATTCG ATCATAGCACCACCCTATCAGCACTGAAAACTCTTTTGCATTAACGGATCATTGCAAGAG CAGCGTGACTGACATTATGAAGGCCTGTACTGAACACAGCAAGCTGTTAGTACAGACCAG ATGCTTTCTTGCAGGCTCGTTGTCCCTCTTGGAAAACTTCAAGCAAGAAAGTGTTTCAGT GCTGGCATATTTTGAAATCTGCACATTCTGGAGGGCAATATACTGTTTAGCTTTCCCCAC CTCCACAAAT |
Restriction Sites | NotI-NotI |
ACCN | NM_016275 |
Insert Size | 4600 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). The expression of this clone is not guaranteed due to the nature of selenoproteins. |
OTI Annotation | This clone encodes a selenoprotein containing the rare amino acid selenocysteine (Sec). Sec is encoded by UGA codon, which normally signals translational termination. Expression of this clone is not guaranteed due to the nature of selenoproteins. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_016275.3, NP_057359.2 |
RefSeq Size | 3498 bp |
Locus ID | 51714 |
UniProt ID | P62341 |
Gene Summary | This gene encodes a selenoprotein, containing a selenocysteine (Sec) residue at the active site. Sec is encoded by the UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is localized in the endoplasmic reticulum. It belongs to the SelWTH family that possesses a thioredoxin-like fold and a conserved CxxU (C is cysteine, U is Sec) motif found in several redox active proteins. Studies in mice indicate a crucial role for this gene in the protection of dopaminergic neurons against oxidative stress in Parkinson's disease, and in the control of glucose homeostasis in pancreatic beta-cells. Pseudogenes of this locus have been identified on chromosomes 9 and 5. [provided by RefSeq, Sep 2017] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC205490 | SELT (Myc-DDK-tagged)-Human selenoprotein T (SELT), (Note, selenocysteine protein, internal stop codon, see reference data summary) |
CNY 998.00 |
|
RC205490L1 | Lenti-ORF, SELT (Myc-DDK-tagged)-Human selenoprotein T (SELT), (Note, selenocysteine protein, internal stop codon, see summary) |
CNY 3,344.00 |
|
RG205490 | SELT (GFP-tagged) - Human selenoprotein T (SELT), (10ug), (Note: selenocysteine protein, Internal stop codon present. see reference data summary below) |
CNY 2,544.00 |