United States
Germany
Japan
United Kingdom
China
PAIP2 (NM_016480) Human Untagged Clone
CAT＃: SC114242
PAIP2 (untagged)-Human poly(A) binding protein interacting protein 2 (PAIP2), transcript variant 2
CNY 1,200.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | PAIP-2; PAIP2A |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC114242 sequence for NM_016480 edited (data generated by NextGen Sequencing)
ATGAAAGATCCAAGTCGCAGCAGTACTAGCCCAAGCATCATCAATGAAGATGTGATTATT AACGGTCATTCTCATGAAGATGACAATCCATTTGCAGAGTACATGTGGATGGAAAATGAA GAAGAATTCAACAGACAAATAGAAGAGGAGTTATGGGAAGAAGAATTTATTGAACGCTGT TTCCAAGAAATGCTGGAAGAGGAAGAAGAGCATGAATGGTTTATTCCAGCTCGAGATCTC CCACAAACTATGGACCAAATCCAAGACCAGTTTAATGACCTTGTTATCAGTGATGGCTCT TCTCTGGAAGATCTTGTGGTCAAGAGCAATCTGAATCCAAATGCAAAGGAGTTTGTTCCT GGGGTGAAGTACGGAAATATTTGA Clone variation with respect to NM_016480.3 >OriGene 5' read for NM_016480 unedited
AAGGTGCACATTAGGTTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGAGGCG GCGGGCGAAGCGCACGTCGAGCGGGGGAGCGGCGCTGCCTGTGGAGATCCGCGGAGGCCG ACAGGATTCGTTGGCTGCCGTCCCCGCTGCTGTGCATTGGGTTAAAAACGACAACCAACA TCAGCCATGAAAGATCCAAGTCGCAGCAGTACTAGCCCAAGCATCATCAATGAAGATGTG ATTATTAACGGTCATTCTCATGAAGATGACAATCCATTTGCAGAGTACATGTGGATGGAA AATGAAGAAGAATTCAACAGACAAATAGAAGAGGAGTTATGGGAAGAAGAATTTATTGAA CGCTGTTTCCAAGAAATGCTGGAAGAGGAAGAAGAGCATGAATGGTTTATTCCAGCTCGA GATCTCCCACAAACTATGGACCAAATCCAAGACCAGTTTAATGACCTTGTTATCAGTGAT GGCTCTTCTCTGGAAGATCTTGTGGTCAAGAGCAATCTGAATCCAAATGCAAAGGAGTTT GTTCCTGGGGTGAAGTACGGAAATATTTGAGTAGACGGGGCCCTCTTTTGGTGGATGTAG CACAATTTCCACACTGTGAAGGCAGTATTAGAAGACTTAATTGTAAAAGCTCTCTTGTCA CTGTGTTACACTTATGCATTGCCAAAGTTTTTGTTAGTCTTGCATGCTTAATAAAAGTGC TGAGACTGTTACTAAGTAAAAAGCTGTCAAACATTTACTGAAAATAGAATTGGCCCCATG GCTTGATGTGAAGACAGCACGGAAAGAACACCAGTCAAGTTGTGAACAAGCCCCAATTAA AGACCTAACCTTACCAAATGTCTTTTTTTTGAGGCTATCTATCACTGTTAATGGTTAACT TTAAATCATACATTTAATTTGATTCCAAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_016480 |
| Insert Size | 1250 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_016480.2, NP_057564.2 |
| RefSeq Size | 1514 bp |
| RefSeq ORF | 384 bp |
| Locus ID | 51247 |
| UniProt ID | Q9BPZ3 |
| Gene Summary | Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207342 | PAIP2 (Myc-DDK-tagged)-Human poly(A) binding protein interacting protein 2 (PAIP2), transcript variant 2 |
CNY 1,200.00 |
|
| RC207342L1 | Lenti ORF clone of Human poly(A) binding protein interacting protein 2 (PAIP2), transcript variant 2, Myc-DDK-tagged |
CNY 3,600.00 |
|
| RC207342L2 | Lenti ORF clone of Human poly(A) binding protein interacting protein 2 (PAIP2), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC207342L3 | Lenti ORF clone of Human poly(A) binding protein interacting protein 2 (PAIP2), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC207342L4 | Lenti ORF clone of Human poly(A) binding protein interacting protein 2 (PAIP2), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG207342 | PAIP2 (tGFP-tagged) - Human poly(A) binding protein interacting protein 2 (PAIP2), transcript variant 2 |
CNY 2,800.00 |
