Junctional Adhesion Molecule 1 (F11R) (NM_016946) Human Untagged Clone

CAT#: SC114147

F11R (untagged)-Human F11 receptor (F11R)



  "NM_016946" in other vectors (6)

CNY 3,600.00


货期*
现货

规格
    • 10 ug

Cited in 1 publication.

Product images

经常一起买 (3)
F11R mouse monoclonal antibody, clone OTI3H3 (formerly 3H3)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms CD321; JAM; JAM1; JAMA; JCAM; KAT; PAM-1
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC114147 sequence for NM_016946 edited (data generated by NextGen Sequencing)
ATGGGGACAAAGGCGCAAGTCGAGAGGAAACTGTTGTGCCTCTTCATATTGGCGATCCTG
TTGTGCTCCCTGGCATTGGGCAGTGTTACAGTGCACTCTTCTGAACCTGAAGTCAGAATT
CCTGAGAATAATCCTGTGAAGTTGTCCTGTGCCTACTCGGGCTTTTCTTCTCCCCGTGTG
GAGTGGAAGTTTGACCAAGGAGACACCACCAGACTCGTTTGCTATAATAACAAGATCACA
GCTTCCTATGAGGACCGGGTGACCTTCTTGCCAACTGGTATCACCTTCAAGTCCGTGACA
CGGGAAGACACTGGGACATACACTTGTATGGTCTCTGAGGAAGGCGGCAACAGCTATGGG
GAGGTCAAGGTCAAGCTCATCGTGCTTGTGCCTCCATCCAAGCCTACAGTTAACATCCCC
TCCTCTGCCACCATTGGGAACCGGGCAGTGCTGACATGCTCAGAACAAGATGGTTCCCCA
CCTTCTGAATACACCTGGTTCAAAGATGGGATAGTGATGCCTACGAATCCCAAAAGCACC
CGTGCCTTCAGCAACTCTTCCTATGTCCTGAATCCCACAACAGGAGAGCTGGTCTTTGAT
CCCCTGTCAGCCTCTGATACTGGAGAATACAGCTGTGAGGCACGGAATGGGTATGGGACA
CCCATGACTTCAAATGCTGTGCGCATGGAAGCTGTGGAGCGGAATGTGGGGGTCATCGTG
GCAGCCGTCCTTGTAACCCTGATTCTCCTGGGAATCTTGGTTTTTGGCATCTGGTTTGCC
TATAGCCGAGGCCACTTTGACAGAACAAAGAAAGGGACTTCGAGTAAGAAGGTGATTTAC
AGCCAGCCTAGTGCCCGAAGTGAAGGAGAATTCAAACAGACCTCGTCATTCCTGGTGTGA

Clone variation with respect to NM_016946.4
>OriGene 5' read for NM_016946 unedited
GTTGGATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGCTGTTCCCAGG
AGTCCTTCGGCGGCTGTTGTGTCGGGAGCCTGATCGCGATGGGGACAAAGGCGCAAGTCG
AGAGGAAACTGTTGTGCCTCTTCATATTGGCGATCCTGTTGTGCTCCCTGGCATTGGGCA
GTGTTACAGTGCACTCTTCTGAACCTGAAGTCAGAATTCCTGAGAATAATCCTGTGAAGT
TGTCCTGTGCCTACTCGGGCTTTTCTTCTCCCCGTGTGGAGTGGAAGTTTGACCAAGGAG
ACACCACCAGACTCGTTTGCTATAATAACAAGATCACAGCTTCCTATGAGGACCGGGTGA
CCTTCTTGCCAACTGGTATCACCTTCAAGTCCGTGACACGGGAAGACACTGGGACATACA
CTTGTATGGTCTCTGAGGAAGGCGGCAACAGCTATGGGGAGGTCAAGGTCAAGCTCATCG
TGCTTGTGCCTCCATCCAAGCCTACAGTTAACATCCCCTCCTCTGCCACCATTGGGACCG
GGGGCAGTGCTGACATGCTCAGAACAAGATGGTTCCCCACCTTCTGAATACACCTGGTTC
ANAGATGGGATAGTGATGCCTACGAATCCCAAAAGCACCCGTGCCTTCAGCAACTCTTCC
TATGTCCTGAATCCCACACAGGAGAGCTGGTCTTTGATCCCCTGTCAGCCTCTGATACTG
GAGAATACAGCTGTGAGCACGGATGGGGTATGGGACACCCATGACTTCAAATGCTGTGCG
CATGGAAGCTGTGGAGCGGATGGTGGGGGGGTCATCGTGGCAGCCGTTCTTGTACCCTGN
ATCTCTGGGATCTGGGGTTTTTGCATCCGGGTTTGCTATAGCCGAGCCACTTTGACAGAA
CAAAAAGGGACTCGAGTTAGAAGGTGAT
>OriGene 3' read for NM_016946 unedited
GGGGNGACNNCCNTCCNNTNNNNNNNANNNNTTTCTTGNACCCGGCCGCATTCTANATCG
AGTTTTTTTTTTTTTTTTTTCAATGTGAAATAAACTTTATTATAAAAATTAGTTTTGACA
TTTTAAAGTGAATGCAGACAAGGTGTTTTCCAGTTCAAAAGGTCCATTGTAAGCTAGAGA
AGTAAATTCCAAGGCTGGCAATAACTGACTCATATTCTTCACAAGTGGCCTAGACAATAA
GGAACCATTCACCTCAAATTCACAGAGCCATGAATCACCTCTGCTTCCCCATGACCTTTT
CCATATCCTTCCTACTCTGTCTTCCAACCATGACACAGAACTGAAACATACTTTAAAAAT
CTCATCCTTGGCTAGGCACGGTGGCTCACATCTGTAATCCCATCACTTTGGGAGGCCAAG
GCAGGCGGATCAAGAGGTCAGGAGTTCGAGACCAGCCCGACCAACATGGTGAAACCCTGT
CTCTACTAAAAACACAAAAACTAGCCAGGCATGGTGGCACGCACCCGCAATCCCAGCTAC
TCAGGAGACTGAGGCAGGAGAATGGCTTGACCCCCGGAGGCGAGGTTACAGTGAGCCAAG
ATCATACCACTGCACTCCAGCCTGNGTGACAGAGCGAGACTCCGTCTTTAANNAAACAAA
CANNACAAACCAAANACACCAACTCCTCTTTACTGACCATTTCATAAGCTTACTTTATTT
GNCTAGTGGGATTTCATTTCTTCTGGAAAATTATTGNTTATTGGCATGTGACCCTTGACT
GATGGCTCCATTAGCATTTTGTTTTCCTTTTGGATCCCTAATGAAAACTAATTCTGTTAG
GGATTTCAAAAAGAATAGGCAAAGCCCACCTAATTTATCCTCCACGAAGAAGAAGCAAAT
CAGCCAGAAGGGCCTTTACTTGCCCTTGGCTAGTAAAAAAAAAATGGNGGATGTGGTAAA
GGAAAACCAAATGTAGGCCCAAAAGTCCAATGTGAAGAAAAACCATGACAC
Restriction Sites NotI-NotI     
ACCN NM_016946
Insert Size 3700 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_016946.3, NP_058642.1
RefSeq Size 3660 bp
RefSeq ORF 900 bp
Locus ID 50848
UniProt ID Q9Y624
Domains ig, IGv, IGc2, IG
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), Epithelial cell signaling in Helicobacter pylori infection, Leukocyte transendothelial migration, Tight junction
Gene Summary Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of this gene. The extent of this transcript is supported by transcript alignments.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

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