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MVP (NM_017458) Human Untagged Clone
CAT＃: SC114118
MVP (untagged)-Human major vault protein (MVP), transcript variant 1
CNY 6,552.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | LRP; VAULT1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_017458 edited
GAATTCGGCACGAGGGTTGCAGCTACCTGCACTTCTAGATTCATCTTCTTGTGAGCCCTG GGCTTAGGAGTCACCATGGCAACTGAAGAGTTCATCATCCGCATCCCCCCATACCACTAT ATCCATGTGCTGGACCAGAACAGCAACGTGTCCCGTGTGGAGGTCGGGCCAAAGACCTAC ATCCGGCAGGACAATGAGAGGGTACTGTTTGCCCCCATGCGCATGGTGACCGTCCCCCCA CGTCACTACTGCACAGTGGCCAACCCTGTGTCTCGGGATGCCCAGGGCTTGGTGCTGTTT GATGTCACAGGGCAAGTTCGGCTTCGCCACGCTGACCTCGAGATCCGGCTGGCCCAGGAC CCCTTCCCCCTGTACCCAGGGGAGGTGCTGGAAAAGGACATCACACCCCTGCAGGTGGTT CTGCCCAACACTGCCCTCCATCTAAAGGCGCTGCTTGATTTTGAGGATAAAGATGGAGAC AAGGTGGTGGCAGGAGATGAGTGGCTTTTCGAGGGACCTGGCACGTACATCCCCCGGAAG GAAGTGGAGGTCGTGGAGATCATTCAGGCCACCATCATCAGGCAGAACCAGGCTCTGCGG CTCAGGGCCCGCAAGGAGTGCTGGGACCGGGACGGCAAGGAGAGGGTGACAGGGGAAGAA TGGCTGGTCACCACAGTAGGGGCGTACCTCCCAGCGGTGTTTGAGGAGGTTCTGGATTTG GTGGACGCCGTCATCCTTACGGAAAAGACAGCCCTGCACCTCCGGGCTCGGCGGAACTTC CGGGACTTCAGGGGAGTGTCCCGCCGCACTGGGGAGGAGTGGCTGGTAACAGTGCAGGAC ACAGAGGCCCACGTGCCAGATGTCCACGAGGAGGTGCTGGGGGTTGTGCCCATCACCACC CTGGGCCCCCACAACTACTGCGTGATTCTCGACCCTGTCGGACCGGATGGCAAGAATCAG CTGGGGCAGAAGCGCGTGGTCAAGGGAGAGAAGTCTTTTTTCCTCCAGCCAGGAGAGCAG CTGGAACAAGGCATCCAGGATGTGTATGTGCTGTCGGAGCAGCAGGGGCTGCTGCTGAGG GCCCTGCAGCCCCTGGAGGAGGGGGAGGATGAGGAGAAGGTCTCACACCAGGCTGGGGAC CACTGGCTCATCCGCGGACCCCTGGAGTATGTGCCATCTGCCAAAGTGGAGGTGGTGGAG GAGCGCCAGGCCATCCCTCTAGACGAGAACGAGGGCATCTATGTGCAGGATGTCAAGACC GGAAAGGTGCGCGCTGTGATTGGAAGCACCTACATGCTGACCCAGGACGAAGTCCTGTGG GAGAAAGAGCTGCCTCCCGGGGTGGAGGAGCTGCTGAACAAGGGGCAGGACCCTCTGGCA GACAGGGGTGAGAAGGACACAGCTAAGAGCCTCCAGCCCTTGGCGCCCCGGAACAAGACC CGTGTGGTCAGCTACCGCGTGCCCCACAACGCTGCGGTGCAGGTGTACGACTACCGAGAG AAGCGAGCCCGCGTGGTCTTCGGGCCTGAGCTGGTGTCGCTGGGTCCTGAGGAGCAGTTC ACAGTGTTGTCCCTCTCAGCTGGGCGGCCCAAGCGTCCCCATGCCCGCCGTGCGCTCTGC CTGCTGCTGGGGCCTGACTTCTTCACAGACGTCATCACCATCGAAACGGCGGATCATGCC AGGCTGCAACTGCAGCTGGCCTACAACTGGCACTTTGAGGTGAATGACCGGAAGGACCCC CAAGAGACGGCCAAGCTCTTTTCAGTGCCAGACTTTGTAGGTGATGCCTGCAAAGCCATC GCATCCCGGGTGCGGGGGGCCGTGGCCTCTGTCACTTTCGATGACTTCCATAAGAACTCA GCCCGCATCATTCGCACTGCTGTCTTTGGCTTTGAGACCTCGGAAGCGAAGGGCCCCGAT GGCATGGCCCTGCCCAGGCCCCGGGACCAGGCTGTCTTCCCCCAAAACGGGCTGGTGGTC AGCAGTGTGGACGTGCAGTCAGTGGAGCCTGTGGATCAGAGGACCCGGGACGCCCTGCAA CGCAGCGTCCAGCTGGCCATCGAGATCACCACCAACTCCCAGGAAGCGGCGGCCAAGCAT GAGGCTCAGAGACTGGAGCAGGAAGCCCGCGGCCGGCTTGAGCGGCAGAAGATCCTGGAC CAGTCAGAAGCCGAGAAAGCTCGCAAGGAACTTTTGGAGCTGGAGGCTCTGAGCATGGCC GTGGAGAGCACCGGGACTGCCAAGGCGGAGGCCGAGTCCCGTGCGGAGGCAGCCCGGATT GAGGGAGAAGGGTCCGTGCTGCAGGCCAAGCTAAAAGCACAGGCCTTGGCCATTGAAACG GAGGCTGAGCTCCAGAGGGTCCAGAAGGTCCGAGAGCTGGAACTGGTCTATGCCCGGGCC CAGCTGGAGCTGGAGGTGAGCAAGGCTCAGCAGCTGGCTGAGGTGGAGGTGAAGAAGTTC AAGCAGATGACAGAGGCCATAGGCCCCAGCACCATCAGGGACCTTGCTGTGGCTGGGCCT GAGATGCAGGTAAAACTGCTCCAGTCCCTGGGCCTGAAATCAACCCTCATCACCGATGGC TCCACTCCCATCAACCTCTTCAACACAGCCTTTGGGCTGCTGGGGATGGGGCCCGAGGGT CAGCCCCTGGGCAGAAGGGTGGCCAGTGGGCCCAGCCCTGGGGAGGGGATATCCCCCCAG TCTGCTCAGGCCCCTCAAGCTCCTGGAGACAACCACGTGGTGCCTGTACTGCGCTAACTC CTGATTAATACAATGGAAGTTTCTGGGCATTTACAATTTCAAAAAAAAAAAAAAAAAACT CGAC >OriGene 5' read for NM_017458 unedited
TTTGTACTACGATTTACTATAGGGCGGCCGCGCATTCGGCACGAGGGTTGCAGCTACCTG CACTTCTAGATTCATCTTCTTGTGAGCCCTGGGCTTAGGAGTCACCATGGCAACTGAAGA GTTCATCATCCGCATCCCCCCATACCACTATATCCATGTGCTGGACCAGAACAGCAACGT GTCCCGTGTGGAGGTCGGGCCAAAGACCTACATCCGGCAGGACAATGAGAGGGTACTGTT TGCCCCCATGCGCATGGTGACCGTCCCCCCACGTCACTACTGCACAGTGGCCAACCCTGT GTCTCGGGATGCCCAGGGCTTGGTGCTGTTTGATGTCACAGGGCAAGTTCGGCTTCGCCA CGCTGACCTCGAGATCCGGCTGGCCCAGGACCCCTTCCCCCTGTACCCAGGGGAGGTGCT GGAAAAGGACATCACACCCCTGCAGGTGGTTCTGCCCAACACTGCCCTCCATCTAAAGGC GCTGCTTGATTTTGAGGATAAAGATGGAGACAAGGTGGTGGCAGGAGATGAGTGGCTTTT CGAGGGACCTGGCACGTACATCCCCCGGAAGGAAGTGGAGGTCGTGGAGATCATTCAGGC CACCATCATCAGGCAGAACCAGGCTCTGCGGCTCAGGGCCCGCAAGGAGTGCTGNGACCG NGACGGCAAGGAGAGGGTGACAGGGGAAGAATGGCTGGTCACCACAGTANGGGCGTACCT CCCAGCGTGTTGGAAGAGGGTCTGGATTTGGTGGACCCCGCATCCTTACGGAAAGACAGC CCTGCACCTCCGGGCTCGGGGGAACTCCGGNACTTCAAGGGGAGGGGNCCGNCCCCTGGN NGAGGGAGGGNNGGNCACAGNNNCACGCCCNCNAGCCACCGNCCACAAGGCCNNNNCCAG GCCCAG >OriGene 3' read for NM_017458 unedited
AAAAAAACCTTACTTGNACCCGGCCGCATTCTAAGATCGGTTTTTTTTTTTTTTTTTTGA AATGTAAATGCCCAAAAACTTCCTTGTATTAATCAGGAGTTAGCGCAGTACAGGCACCAC GTGGTTGTCTCCAGGAGCTTGAGGGGCCTGAGCAGACTGGGGGGATATCCCCTCCCCCAG GCTGGGCCCACTGGCCACCCTTCTGCCCAGGGGCTGACCCTTGGTGCCCATTCCCAGAAG CCCCAAAGCTGGGTTGAAAAAGGTTGACGGCAAGTGGAACCCCCCCCTGATTGAAGGGTT GATTTTCACGCCCACGGCACTGGAGCACACTATTTCCTGGTTTTTTAAGCCCCCCCCCCC CCCATTGGTCCCTTTTTGGGGGCCGGGGGCCCTTTGTCCCCCTCTCTACAACCCCCCTTG GACTCCTTGTTTTCGCGCCCCCCCCCCCTCGCCCCTTTTCCGTCCAACTCTCTGCTCCCT CCCCCCACCCCCACCCCTGTACCCCGGTTTCTTAATACCTTCTCCCCTTCCTCCGCCCCT CTCTGCCACCTCCCGTGAGCCTCCCCCCCCCTCCTTTTTAACAGCGCGCCACCAACCTGC CTCCTTTCTCACTGCGGGCCTCTGACCAACCACCACCACCTCTCCCCCCCCATCCTTTAT CTGCTCTCTTTCTCCTCCCCCCATGCTCCTCACCCCCCCCCCCCCGTCCATTCTCACCCG TCCTTTTTTTTCTCGCCCATCGCGTCCCGACACCCTCCCCTCTTACTAACAAATTCCCTC CCTTCTTACCCCTTTTTCCCTCCCTCTTCACCACTCCGACATACTCCTTTCTTCTTCCCC TCTCCTCCCTCCTACTCGGCCCCTCTTTCTTCCTTTTCACCCCCCCCTACCTCTCCCACT CTCCTCCACCCGACCTCCTCCCTCCTCCTCTCGCTGCGATCCATTTTACCCATATCTTCC ATCCACTCGCTTTCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_017458 |
| Insert Size | 2820 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_017458.2, NP_059447.2 |
| RefSeq Size | 2857 bp |
| RefSeq ORF | 2682 bp |
| Locus ID | 9961 |
| UniProt ID | Q14764 |
| Domains | Vault |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012] Transcript Variant: This variant (1, also known as L-MVP) is the longest transcript. Variants 1 and 2 encode the same isoform 1. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
MVP Expression Facilitates Tumor Cell Proliferation and Migration Supporting the Metastasis of Colorectal Cancer Cells
,null,
International Journal of Molecular Sciences
,PubMed ID 34829999
[MVP]
|
|
Feedback regulation on PTEN/AKT pathway by the ER stress kinase PERK mediated by interaction with the Vault complex
,Zhang, W;Neo, SP;Gunaratne, J;Poulsen, A;Boping, L;Ong, EH;Sangthongpitag, K;Pendharkar, V;Hill, J;Cohen, SM;,
Cell. Signal.
,PubMed ID 25530215
[MVP]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213533 | MVP (Myc-DDK-tagged)-Human major vault protein (MVP), transcript variant 1 |
CNY 6,544.00 |
|
| RC213533L1 | Lenti ORF clone of Human major vault protein (MVP), transcript variant 1, Myc-DDK-tagged |
CNY 8,944.00 |
|
| RC213533L2 | Lenti ORF clone of Human major vault protein (MVP), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC213533L3 | Lenti ORF clone of Human major vault protein (MVP), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC213533L4 | Lenti ORF clone of Human major vault protein (MVP), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG213533 | MVP (tGFP-tagged) - Human major vault protein (MVP), transcript variant 1 |
CNY 8,144.00 |
