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Apelin (APLN) (NM_017413) Human Untagged Clone
CNY 1,800.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | APEL; XNPEP2 |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_017413, the custom clone sequence may differ by one or more nucleotides
ATGAATCTGCGGCTCTGCGTGCAGGCGCTCCTGCTGCTCTGGCTCTCCTTGACCGCGGTGTGTGGAGGGT CCCTGATGCCGCTTCCCGATGGGAATGGGCTGGAAGACGGCAATGTCCGCCACCTGGTGCAGCCCAGAGG GTCAAGGAATGGGCCAGGGCCCTGGCAGGGAGGTCGGAGGAAATTCCGCCGCCAGCGGCCCCGCCTCTCC CATAAGGGACCCATGCCTTTCTGA >OriGene 5' read for NM_017413 unedited
CCCCCCATACCCCCGCCCGANGCCGCTTTGGGCGGTAGGCGTGTACGGTGGGAGGTCTAT ATAAGCAGATCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCG GCCGCGAATTCGGCACGAGGGGCAGTTGCAGCCGCGGCCGAGCAGCCAGCCGCTAAGAAA GAGCTCGCCGCTGCCGCTCCCGGAGCCGCCGAGGCCAGCTTCGCGGCGCTGCCCCGCGGC GGGAGAGGAGGCTGCAGAAGAGCGGAGGCGGCCAGCGGGAGCGGCGGGGCTCAGCGCGCA CACTCAGCGGCCGGGGAGCCTCCCGAGCTCCGCGCCCGCACGCGCCAGCCGCGGCTCGCG CCTTTCTTGGCCTCCGGGCGCCCGACCTCTCCTCCCCCGCGCCGGCTCGCCGGGGCCGCG GCGGCCCAAGGAGCAGCATGAATCTGCGGCTCTGCGTGCAGGCGCTCCTGCTGCTCTGGC TCTCCTTGACCGCGGTGTGTGGAGGGTCCCTGATGCCGCTTCCCGATGGGAATGGGCTGG AAGACGGCAATGTCCGCCACCTGGTGCAGCCCAGAGGGTCAAGGAATGGGCCAGGGCCCT GGCAGGGAGGTCGGAGGAAATTCCGCCGCCAGCGGCCCCGCCTCTCCCATAAGGGACCCA TGCCTTTCTGAAGCAGGACTGAAGGGGCCCCCAAGTGCCCACCCCCTGCGGTTATGTCTC CTCCATAGAGTGGTCTGCTTCTCTGGAGGCCTCACGTCCATTCAGCTCTCACCTCGCACC TGCTGTAGCCACCAGTGGGCCCAGCTCTTCTCACCTGCCTGCTTCCCCAGTGGCGTGCTC CTGGCATGTAGTTTGGNATGAATCCCCGTCTCTCACAGAAATCCGTCCAGTCCATCATTC TGGCTCC >OriGene 3' read for NM_017413 unedited
TTTTTTAGATACTCTATGNNACCGCGGCCGCAATCTANNATCGAGTTTTTTTTTTTTTTT TTTATTATCAAATGTATTTATTGCTGAAAACATAACATTTTTCAAGAAAGGCAAACTGGC TAAAAAGTCCTGAAAGTGTTCAAAAGTAGATAAAATAGCAGAAGACACCCACCAAGGATA CAAAACAATTTTTAGTAGCGATCCTGCATTTAATCAGTATGTTCTTAAATAAACTGCTTT AAAAAAATTCTTCAAATGACACTGCCAAAAAAATTAGGACACCCAAACAGATGCCAGAAA ACCTGTAAGTGGGCTGGATTTTATGTGACCTGGTCATTAAGCATAGGGATTCATTTTGTG AGCTCATGGCAAATCAGTTTGAGGCCAGTTGACCTAGAACCGATTTGGGATGCAGGCACT TACCTCCCTGCACGTGCAATATGTGGGCATGGGGACACCCATGACCCCCAGGGGAAAGGA ATGCCCCTCCTGAACATGACCTCCAAGAGTAAGGGCGAACTGTCAGCTTTTAACTGTTTA TTATTAAGACATATTTACACAGAACAATCTTTACAAACATTGAACACAGGGGAAGGGGAC AATTTCTTAATGAACAGGGCCTATATATCTTTGTATAAAATAGTATAAGAATCATAAACC ACCCCTTTAAATAGGGCACCCCCCTTAGCCCACCCACTACACTTTTTTGTTCCCTAATCT CCCAATTTTCTTAAACATCCCCCCACTTTTCTCCCCTTTCCCAACGGGGCTTGGGCTTTG GCTTGCACGTTAATGGCAAGGTCCGTTGAGGCCGGGAGCACAACGGAAGGGGAGGGGGAA AAGAAAGGCCCAATCCCCTGGAGGGGGGCCGCATGGGGCGAAAGAGAATTTTTCGGGA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_017413 |
| Insert Size | 3500 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_017413.3, NP_059109.3 |
| RefSeq Size | 3125 bp |
| RefSeq ORF | 234 bp |
| Locus ID | 8862 |
| UniProt ID | Q9ULZ1 |
| Protein Families | Druggable Genome, Secreted Protein |
| Gene Summary | This gene encodes a peptide that functions as an endogenous ligand for the G-protein coupled apelin receptor. The encoded preproprotein is proteolytically processed into biologically active C-terminal peptide fragments. These peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1. [provided by RefSeq, Feb 2016] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Serum apelin is associated with left ventricular hypertrophy in untreated hypertension patients
,Ye, L;Ding, F;Zhang, L;Shen, A;Yao, H;Deng, L;Ding, Y;,
J Transl Med
,PubMed ID 26342945
[APLN]
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Resources
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