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USP49 (NM_018561) Human Untagged Clone
CAT＃: SC113428
USP49 (untagged)-Human ubiquitin specific peptidase 49 (USP49)
CNY 4,776.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_018561, the custom clone sequence may differ by one or more nucleotides
ATGGATAGATGCAAACATGTAGGGCGGTTACGGCTCGCCCAGGACCACTCCATCCTGAACCCTCAGAAGT GGTGCTGCTTAGAGTGTGCCACCACCGAGTCCGTGTGGGCCTGCCTCAAGTGCTCCCACGTGGCCTGCGG CCGCTATATTGAGGACCACGCCCTGAAACACTTTGAGGAGACGGGACACCCGCTAGCCATGGAAGTCCGG GATCTCTACGTGTTCTGTTACCTGTGCAAGGACTACGTGCTCAATGATAACCCAGAGGGGGACCTGAAGC TGCTAAGAAGCTCCCTCCTGGCGGTCCGGGGCCAGAAACAGGACACGCCGGTGAGACGTGGGCGGACGCT GCGGTCCATGGCTTCGGGTGAGGACGTGGTCCTGCCGCAGCGCGCTCCTCAGGGACAGCCGCAGATGCTC ACGGCTCTGTGGTACCGGCGTCAGCGCCTGCTGGCCAGGACGCTGCGGCTGTGGTTCGAGAAGAGCTCCC GGGGCCAGGCGAAGCTGGAGCAGCGGCGGCAGGAGGAGGCCCTGGAGCGCAAGAAGGAGGAGGCGCGGAG GCGGCGGCGCGAGGTGAAACGGCGGCTGCTGGAGGAGCTGGCCAGCACCCCTCCGCGCAAGAGTGCACGG CTGCTCCTGCACACGCCCCGCGACGCGGGCCCGGCTGCCTCGCGCCCCGCCGCCCTCCCTACCTCACGCA GAGTGCCCGCCGCCACACTCAAGCTGCGTCGCCAGCCGGCCATGGCCCCAGGCGTCACGGGCCTGCGCAA CCTGGGCAACACCTGCTACATGAACTCCATCCTCCAGGTGCTCAGCCACCTCCAGAAGTTCCGAGAATGT TTCCTCAACCTTGACCCTTCCAAAACGGAACATCTGTTTCCCAAAGCCACCAACGGGAAGACTCAGCTTT CTGGCAAGCCAACCAACAGCTCGGCCACGGAGCTGTCCTTGAGAAATGACAGGGCCGAGGCATGCGAGCG GGAGGGCTTCTGCTGGAACGGCAGGGCCTCCATTAGTCGGAGTCTGGAGCTCATCCAGAACAAGGAGCCG AGTTCAAAGCACATTTCCCTCTGCCGTGAACTGCACACCCTCTTCCGAGTCATGTGGTCCGGGAAGTGGG CCCTAGTGTCGCCCTTCGCCATGCTCCACTCAGTGTGGAGCCTGATCCCTGCCTTCCGCGGCTACGACCA ACAGGACGCGCAGGAATTTCTCTGCGAGCTGCTGCACAAGGTGCAGCAGGAACTCGAGTCTGAGGGCACC ACACGCCGGATCCTCATCCCCTTCTCCCAGAGGAAGCTCACCAAACAGGTCTTAAAGGTGGTGAATACCA TATTTCATGGGCAGCTGCTCAGTCAGGTCACATGTATATCATGCAATTACAAATCCAATACCATTGAGCC CTTTTGGGACCTATCCCTGGAATTCCCTGAACGCTATCACTGCATAGAAAAGGGGTTTGTCCCTTTGAAT CAAACAGAGTGCTTGCTCACTGAGATGCTGGCCAAATTCACAGAGACAGAGGCCCTGGAAGGGAGAATCT ACGCTTGTGACCAGTGTAACAGCAAACGACGAAAATCCAATCCCAAACCCCTTGTTCTGAGTGAAGCTAG AAAGCAGTTAATGATCTACAGACTACCTCAGGTTCTCCGGCTGCACCTTAAAAGATTCAGGTGGTCTGGC CGTAATCATCGAGAGAAGATTGGGGTCCATGTCGTCTTTGACCAGGTATTAACCATGGAACCTTACTGCT GCAGGGACATGCTCTCCTCTCTTGACAAAGAGACCTTTGCCTATGATCTCTCCGCAGTGGTCATGCATCA CGGGAAAGGGTTTGGCTCAGGACACTACACAGCCTATTGCTACAACACAGAGGGAGGTGCGTGCGCTTTA CTCTGTGGGGTGGGGGACACGGAAAGGGGTTGA >OriGene 5' read for NM_018561 unedited
TTACCCCCGCCCCGTTGGCGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAG CAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGC GAATTCGGCACGAGGGCAAGATCCAAGGTGAAAACAGTGAGGTAAAGAGACAGGGCTAAA AGCAAATGGTGAGAGGAGCAGGAAGAGATGGGCCCCAGAATTTAAAGGATGAGATGGGGA GTAAGGGAAGAGAGGGGGCTAAGAGAAGCTGGGGGAGTCCTGATGGATGTAGAACTGGGG TAGACTGCAGGGGGGTGGGAATCGAATGTGCGTGTTATGGGGAGTTGCTCCAGAAGGTCT GCAAGGGTCAGGGCAGAAATGCTGTAGTGAAAGATCAAGTGTAAGAGAGCCTTTGGTGCA GAAGACGAGGAACCATGATTCTTTGGATGGGAAGAGACCTTGAAAGGACCTCTAGTTTAT CCTGCAACTCCAGTCAATATCCCACTTAAATCATTCCAGGTAATAGAGAAGAGGAAACCT AACCAATGACTGTGGAATAATATGGAAGAAGATGGAAAAAACTTGTTTAATGGGTTGAGA AAGTGGCGACTTCTATAAGACATGGATAGATGCAAACATGTAGGGGCGGNTACGGCTCGC CCAGGACCACTCCATTCCTGAACCTCAGAAGTGGTGCTGCTTAGAGTGTGCCACCACCGA GTCCGTGTGGGCCTGCCTCAAGTGCTCCCACGTTGGCCTGCGGCCGCTATATTGAGGACC ACGCCCTGAAACACTTTGAGAGACGGGACACCCGCTAGGCATGGAAGTCCGGGATCTTTA CGTGTTTTGGTTACCTGTGCAAGGCTTCGTTGTCAATGATAACCCAGAGGNGGCCCTGAA CTGTTAAAAGCTCCTTCTGGCGGTCCGGGCCAAAACAGACACCCCGGTGAACTGGTCGGC A |
| Restriction Sites | NotI-NotI |
| ACCN | NM_018561 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_018561.3, NP_061031.2 |
| RefSeq Size | 3194 bp |
| RefSeq ORF | 1923 bp |
| Locus ID | 25862 |
| UniProt ID | Q70CQ1 |
| Domains | UCH, zf-UBP |
| Protein Families | Protease, Transcription Factors |
| Gene Summary | Specifically deubiquitinates histone H2B at 'Lys-120' (H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR, and it includes alternate 3' exon structure and thus differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (b) has a distinct C-terminus and is shorter than isoform a. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204345 | USP49 (Myc-DDK-tagged)-Human ubiquitin specific peptidase 49 (USP49) |
CNY 4,768.00 |
|
| RC204345L1 | Lenti ORF clone of Human ubiquitin specific peptidase 49 (USP49), Myc-DDK-tagged |
CNY 7,168.00 |
|
| RC204345L2 | Lenti ORF clone of Human ubiquitin specific peptidase 49 (USP49), mGFP tagged |
CNY 6,460.00 |
|
| RC204345L3 | Lenti ORF clone of Human ubiquitin specific peptidase 49 (USP49), Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC204345L4 | Lenti ORF clone of Human ubiquitin specific peptidase 49 (USP49), mGFP tagged |
CNY 6,460.00 |
|
| RG204345 | USP49 (tGFP-tagged) - Human ubiquitin specific peptidase 49 (USP49) |
CNY 6,368.00 |
