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DLL4 (NM_019074) Human Untagged Clone
CAT＃: SC113239
DLL4 (untagged)-Human delta-like 4 (Drosophila) (DLL4)
CNY 7,536.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AOS6; delta4; hdelta2 |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>SC113239 representing NM_019074.
Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGCGGCAGCGTCCCGGAGCGCCTCTGGCTGGGCGCTACTGCTGCTGGTGGCACTTTGGCAGCAGCGC GCGGCCGGCTCCGGCGTCTTCCAGCTGCAGCTGCAGGAGTTCATCAACGAGCGCGGCGTACTGGCCAGT GGGCGGCCTTGCGAGCCCGGCTGCCGGACTTTCTTCCGCGTCTGCCTTAAGCACTTCCAGGCGGTCGTC TCGCCCGGACCCTGCACCTTCGGGACCGTCTCCACGCCGGTATTGGGCACCAACTCCTTCGCTGTCCGG GACGACAGTAGCGGCGGGGGGCGCAACCCTCTCCAACTGCCCTTCAATTTCACCTGGCCGGGTACCTTC TCGCTCATCATCGAAGCTTGGCACGCGCCAGGAGACGACCTGCGGCCAGAGGCCTTGCCACCAGATGCA CTCATCAGCAAGATCGCCATCCAGGGCTCCCTAGCTGTGGGTCAGAACTGGTTATTGGATGAGCAAACC AGCACCCTCACAAGGCTGCGCTACTCTTACCGGGTCATCTGCAGTGACAACTACTATGGAGACAACTGC TCCCGCCTGTGCAAGAAGCGCAATGACCACTTCGGCCACTATGTGTGCCAGCCAGATGGCAACTTGTCC TGCCTGCCCGGTTGGACTGGGGAATATTGCCAACAGCCTATCTGTCTTTCGGGCTGTCATGAACAGAAT GGCTACTGCAGCAAGCCAGCAGAGTGCCTCTGCCGCCCAGGCTGGCAGGGCCGGCTGTGTAACGAATGC ATCCCCCACAATGGCTGTCGCCACGGCACCTGCAGCACTCCCTGGCAATGTACTTGTGATGAGGGCTGG GGAGGCCTGTTTTGTGACCAAGATCTCAACTACTGCACCCACCACTCCCCATGCAAGAATGGGGCAACG TGCTCCAACAGTGGGCAGCGAAGCTACACCTGCACCTGTCGCCCAGGCTACACTGGTGTGGACTGTGAG CTGGAGCTCAGCGAGTGTGACAGCAACCCCTGTCGCAATGGAGGCAGCTGTAAGGACCAGGAGGATGGC TACCACTGCCTGTGTCCTCCGGGCTACTATGGCCTGCATTGTGAACACAGCACCTTGAGCTGCGCCGAC TCCCCCTGCTTCAATGGGGGCTCCTGCCGGGAGCGCAACCAGGGGGCCAACTATGCTTGTGAATGTCCC CCCAACTTCACCGGCTCCAACTGCGAGAAGAAAGTGGACAGGTGCACCAGCAACCCCTGTGCCAACGGG GGACAGTGCCTGAACCGAGGTCCAAGCCGCATGTGCCGCTGCCGTCCTGGATTCACGGGCACCTACTGT GAACTCCACGTCAGCGACTGTGCCCGTAACCCTTGCGCCCACGGTGGCACTTGCCATGACCTGGAGAAT GGGCTCATGTGCACCTGCCCTGCCGGCTTCTCTGGCCGACGCTGTGAGGTGCGGACATCCATCGATGCC TGTGCCTCGAGTCCCTGCTTCAACAGGGCCACCTGCTACACCGACCTCTCCACAGACACCTTTGTGTGC AACTGCCCTTATGGCTTTGTGGGCAGCCGCTGCGAGTTCCCCGTGGGCTTGCCGCCCAGCTTCCCCTGG GTGGCCGTCTCGCTGGGTGTGGGGCTGGCAGTGCTGCTGGTACTGCTGGGCATGGTGGCAGTGGCTGTG CGGCAGCTGCGGCTTCGACGGCCGGACGACGGCAGCAGGGAAGCCATGAACAACTTGTCGGACTTCCAG AAGGACAACCTGATTCCTGCCGCCCAGCTTAAAAACACAAACCAGAAGAAGGAGCTGGAAGTGGACTGT GGCCTGGACAAGTCCAACTGTGGCAAACAGCAAAACCACACATTGGACTATAATCTGGCCCCAGGGCCC CTGGGGCGGGGGACCATGCCAGGAAAGTTTCCCCACAGTGACAAGAGCTTAGGAGAGAAGGCGCCACTG CGGTTACACAGTGAAAAGCCAGAGTGTCGGATATCAGCGATATGCTCCCCCAGGGACTCCATGTACCAG TCTGTGTGTTTGATATCAGAGGAGAGGAATGAATGTGTCATTGCCACGGAGGTATAA >OriGene 5' read for NM_019074 unedited
CCCCCGCCCTGTTGCCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAG AGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGAA TTCGGCACGAGGCTGCGCGCAGGCCGGGAACACGAGGCCAAGAGCCGCAGCCCCAGCCGC CTTGGTGCAGCGTACACCGGCACTAGCCCGCTTGCAGCCCCAGGATTAGACAGAAGACGC GTCCTCGGCGCGGTCGCCGCCCAGCCGTAGTCACCTGGATTACCTACAGCGGCAGCTGCA GCGGAGCCAGCGAGAAGGCCAAAGGGGAGCAGCGTCCCGAGAGGAGCGCCTCTTTTCAGG GACCCCGCCGGCTGGCGGACGCGCGGGAAAGCGGCGTCGCGAACAGAGCCAGATTGAGGG CCCGCGGGTGGAGAGAGCGACGCCCGAGGGGATGGCGGCAGCGTCCCGGAGCGCCTCTGG CTGGGCGCTACTGCTGCTGGTGGCACTTTGGCAGCAGCGCGCGGCCGGCTCCGGCGTCTT CCAGCTGCAGCTGCAGGAGTTCATCAACGAGCGCGGCGTACTGGCCAGTGGGCGGCCTTG CGAGCCCGGCTGCCGGACTTTCTTCCGCGTCTGCCTTAAGCACTTCCAGGCGGTCGTCTC GCCCGGACCCTGCACCTTCGGGACCGTCTCCACGCCGGTATTGGGCACCAACTCCTTCGC TGTCCGGGACGACAGTAGCGGCGGGGGGCGNCACCCTCTNCACTGCCCTTCATNTCACCT GGCCGGGTACCTTCTCGCTCATCATCGAAGCTGGCCACGCGCCAGGAGACGACCTGGCGG CAGAGGCCTTGNCACCAGATGCACTCATCAGCAAGATCGCCATCCAGGGCTCCCTAGCTG TGGGTCAGAACTGGGTATGGGNATGAGCAACAGCACCTNACAGGCTGCGCTACTCTTACC GGTCATCTGCATGC >OriGene 3' read for NM_019074 unedited
GTTTATCTATGNNACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTCCTG TACACATCTGTTTCATATTATAAATACACATTATATACAAAATAATGTTATAAAATGTAG AAAGGTCAGTGCTTCTGATTCTTAAATTATTGAAATACTAGACTCCAAAATAAACTACAA AAAAAAAAAAAAAAACAAAATAAAAACTCATATTATTGATTTCTGAAAACCAGCTTTGAG GGTGGTCTGGGGCAGTAGTGGACCAAAGCCCAGGCTCGAGGTTGTGGAAATGGGCTTGAG GGAGGAAAGGGCCCAGGCGGCCGCAGCACCTGATTTCCCCCTCAGTGGAATTTCCAACAC ACTGCCCTGAGTGCCCCAGTTAGGCCTGGCACCCTTGGCTGGTGGGAGGGGCAGGCCCTC TGCCTGTCTGCTTACAGAAGCCCAGGGCCAAAGGGTGGTGGAAGCCGGGTAAACGGACAT TCTTGCCCAAAGGGCCTAGACCAAAGAGCCAGGCCTGCATACAGTAATTGGAGGCATGGG GCANAAAGCACTCCCCTCCCTNGAGCACTCACCTCACCTCCAGGGGAAACCCCAGCAAGA GACCCACCCCAGTGGTTTTTCAACCCACAAGAGGCCCCTGCCCTCATTGGCCCCCCTCTC TCCTTTCTGATTTGGGCCCCAACTGTCGCCGTGGAGACCCGGGCCAAAGCACCTTTTGGA ACACCGAAGCCCATTGGAGGCCACAAAAACTTCCGGGCCCCATGGGGCTACTGGCACCTC TCTTCGGGAAAAAGGGCCGGAACCCCGGAAGGAGCCCCCTGGAGGCCCCTTATGGGAGGG GAAGGGCCCAATGGCTTCCTCTCTCCCTTTTGGTCCCCCGGGGGGGGGGCACTTGCCATT TTGATGCCCAAAGAACCCCAAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_019074 |
| Insert Size | 2058 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_019074.2 |
| RefSeq Size | 3383 bp |
| RefSeq ORF | 2058 bp |
| Locus ID | 54567 |
| UniProt ID | Q9NR61 |
| Domains | DSL, EGF |
| Protein Families | Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Transmembrane |
| Protein Pathways | Notch signaling pathway |
| MW | 74.6 kDa |
| Gene Summary | This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. [provided by RefSeq, Jul 2008] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Role of delta-like ligand-4 in chemoresistance against docetaxel in MCF-7 cells
,Wang, Q;Shi, Y;Butler, HJ;Xue, J;Wang, G;Duan, P;Zheng, H;,
Hum Exp Toxicol
,PubMed ID 27334972
[DLL4]
|
|
Endothelial Delta-like 4 (DLL4) promotes renal cell carcinoma hematogenous metastasis
,null,
Oncotarget
,PubMed ID 24931473
[DLL4]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC212628 | DLL4 (Myc-DDK-tagged)-Human delta-like 4 (Drosophila) (DLL4) |
CNY 7,528.00 |
|
| RC212628L1 | Lenti ORF clone of Human delta-like 4 (Drosophila) (DLL4), Myc-DDK-tagged |
CNY 9,928.00 |
|
| RC212628L2 | Lenti ORF clone of Human delta-like 4 (Drosophila) (DLL4), mGFP tagged |
CNY 5,890.00 |
|
| RC212628L3 | Lenti ORF clone of Human delta-like 4 (Drosophila) (DLL4), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC212628L4 | Lenti ORF clone of Human delta-like 4 (Drosophila) (DLL4), mGFP tagged |
CNY 9,928.00 |
|
| RG212628 | DLL4 (tGFP-tagged) - Human delta-like 4 (Drosophila) (DLL4) |
CNY 9,128.00 |
