United States
Germany
Japan
United Kingdom
China
UGT (UGT2B4) (NM_021139) Human Untagged Clone
CAT＃: SC112983
UGT2B4 (untagged)-Human UDP glucuronosyltransferase 2 family, polypeptide B4 (UGT2B4)
CNY 5,904.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HLUG25; UDPGT2B4; UDPGTh-1; UDPGTH1; UGT2B11 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC112983 sequence for NM_021139 edited (data generated by NextGen Sequencing)
ATGTCTATGAAATGGACTTCAGCTCTTCTGCTGATACAGCTGAGCTGTTACTTTAGCTCT GGGAGTTGTGGAAAGGTGCTGGTGTGGCCCACAGAATTCAGCCACTGGATGAATATAAAG ACAATCCTGGATGAACTTGTCCAGAGAGGTCATGAGGTGACTGTATTGGCATCTTCAGCT TCCATTTCTTTCGATCCCAACAGCCCATCTACTCTTAAATTTGAAGTTTATCCTGTATCT TTAACTAAAACTGAGTTTGAGGATATTATCAAGCAGCTGGTTAAGAGATGGGCAGAACTT CCAAAAGACACATTTTGGTCATATTTTTCACAAGTACAAGAAATCATGTGGACATTTAAT GACATACTTAGAAAGTTCTGTAAGGATATAGTTTCAAATAAGAAACTTATGAAGAAACTA CAGGAGTCAAGATTTGATGTTGTTCTTGCAGATGCTGTTTTCCCCTTTGGTGAGCTGCTG GCCGAGTTACTTAAAATACCCTTTGTCTACAGCCTCCGCTTCTCTCCTGGCTACGCAATT GAAAAGCATAGTGGAGGACTTCTGTTCCCTCCTTCCTATGTGCCTGTTGTTATGTCAGAA CTAAGTGACCAAATGACTTTCATAGAGAGGGTAAAAAATATGATCTATGTGCTTTATTTT GAATTTTGGTTCCAAATATTTGACATGAAGAAGTGGGATCAGTTCTACAGTGAAGTTCTA GGAAGACCCACTACGTTATCTGAGACAATGGCAAAAGCTGACATATGGCTTATTCGAAAC TACTGGGATTTTCAATTTCCTCACCCACTCTTACCAAATGTTGAGTTCGTTGGAGGACTC CACTGCAAACCTGCCAAACCCCTACCGAAGGAAATGGAAGAGTTTGTCCAGAGCTCTGGA GAAAATGGTGTTGTGGTGTTTTCTCTGGGGTCGATGGTCAGTAACACGTCAGAAGAAAGG GCCAATGTAATTGCATCAGCCCTTGCCAAGATCCCACAAAAGGTTCTGTGGAGATTTGAT GGGAATAAACCAGATACTTTAGGACTCAATACTCGGCTGTACAAGTGGATACCCCAGAAT GATCTTCTTGGTCACCCAAAAACCAGAGCTTTTATAACTCATGGTGGAGCCAATGGCATC TATGAGGCAATCTACCATGGAATCCCTATGGTGGGCGTTCCATTGTTTGCAGATCAACCT GATAACATTGCACACATGAAGGCCAAGGGAGCAGCTGTTAGTTTGGACTTCCACACAATG TCGAGTACAGACTTACTCAATGCACTGAAGACAGTAATTAATGATCCTTTATATAAAGAG AATGCTATGAAATTATCAAGAATTCATCATGATCAACCAGTGAAGCCCCTTGATCGAGCA GTCTTCTGGATTGAATTTGTCATGCGCCATAAAGGAGCCAAGCACCTTCGGGTTGCAGCC CACGACCTCACCTGGTTCCAGTACCACTCTTTGGATGTGACTGGGTTCCTGCTGGCCTGT GTGGCAACTGTGATATTCATCATCACAAAATGTCTGTTTTGTGTCTGGAAGTTTGTTAGA ACAGGAAAGAAGGGGAAAAGAGATTAA Clone variation with respect to NM_021139.2 >OriGene 5' read for NM_021139 unedited
CTTTTGTATACACTCCTATAGGGCGGCCGCGAATTCGCACCAGGNAAAACAAGCATTGCA TTGCATCAGGATGTCTATGAAATGGACTTCAGCTCTTCTGCTGATACAGCTGAGCTGTTA CTTTAGCTCTGGGAGTTGTGGAAAGGTGCTGGTGTGGCCCACAGAATTCAGCCACTGGAT GAATATAAAGACAATCCTGGATGAACTTGTCCAGAGAGGTCATGAGGTGACTGTATTGGC ATCTTCAGCTTCCATTTCTTTCGATCCCAACAGCCCATCTACTCTTAAATTTGAAGTTTA TCCTGTATCTTTAACTAAAACTGAGTTTGAGGATATTATCAAGCAGCTGGTTAAGAGATG GGCAGAACTTCCAAAAGACACATTTTGGTCATATTTTTCACAAGTACAAGAAATCATGTG GACATTTAATGACATACTTAGAAAGTTCTGTAAGGATATAGTTTCAAATAAGAAACTTAT GAAGAAACTACAGGAGTCAAGATTTGATGTTGTTCTTGCAGATGCTGTTTTCCCCTTTGG TGAGCTGCTGGCCGAGTTACTTAAAATACCCTTTGTCTACAGCCTCCGCTTCTCTCCTGG CTACGCAATTGAAAAGCATAGTGGAGGACTTCTGTTCCCTCCTTCCTATGTGCCTGTTGN TATGTCAGAACTAAGTGACCAAATGACTTTCATAGAGAGGGTAAAAAATATGATCTATGT GCTNTATTTTGAATTTTGGTTCCAAATATTTGACATGAAGAAGTGGGATCAGTTCTACAG TGAAGTTCTAGGAAGACCCACTACNGTATCTGAGACAATGGCAAAAGCTGACATATGGCC TTATTCGAAACTACTGGGGATTTTTCAATTTCCTCACCCACTCTTACCANATGNTTGAGN TCGGTTGGAGGAACTCCACTGCAACCTGCCAAACCCCTACGNNAGAAATGGAAGAGTTTG TCCGAGCTTGAGAAAAGNGGGTGTNGGGGGTTTT >OriGene 3' read for NM_021139 unedited
NCACTCTGNNACCGCGGCCGCATNCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTACA ATTTAATTATTTATTAGTTTCCTCAACAACAGTTAAAACAACACAATCCTGCATGAAATG GATCCAAAGTATGCTGAGTATTTGCAAAACAGTACTGATACTGTCAGTGGACTTCTTAAT GTTCTTGTTTCCATGTACAATGTGTGACATGTAGTTAAGCTTAGTAAATTTTTTTTCATG TAACCTGTGAATTGGAACAATAAATTTCAATATAAGCTCAATACATTTCAATATAACCTC GTATGGCTTTATATCATTTTTGTTTTCCCTAATGTTTTCCTCCTTGACATGAAATATTTC TAATGGTTAAACAGGTACTAAAACAAATTTTGACTTGACAAGGTAAGTTTTGAAAGATGT TTTGTCACAAGAAGAAAGGAATCTCTTGTATCACAACGTCTTCTTGTTGTAATAAACTAA AGGAGTTCATTTATTGGGTTTCCCAGCTTCCAGCCTCAGACGTAATTAATCTCTTTTCCC CTTCTTTCCTGTTCTAACAAACTTCCAGACACAAAACAGACATTNTGTGATGATGAATAT CACAGTTGCCACACAGGCCAGCAGGAACCCAGTCACATCCAAAGAGTGGTACTGGAACCA GGTGANGTCGTGGGCTGCAACCCGAAGTGCTTGNCTNCTTTTATGCGCATGACANATTCA TNCCAGAGACTGCTCGATCAAGGGGCTCACTGGNTGATCATGATGAATTCTTGATAATTN CATAGCATNCTCTTTATATAAAGGATCATTAATACTGNNCTCAGNGCATTGAGTAAGTCT GTACTCGACATTGNGTGGAAGTTCAAACTACAGCTGCTCCTTTGGCCTCATGNNGTGCAT GTATCAAGGTGATCTGCAACCATGGNAACGCCACATANGGATNCATGGTAAAATGC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_021139 |
| Insert Size | 2240 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_021139.1, NP_066962.1 |
| RefSeq Size | 2093 bp |
| RefSeq ORF | 1587 bp |
| Locus ID | 7363 |
| UniProt ID | P06133 |
| Domains | UDPGT |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Androgen and estrogen metabolism, Ascorbate and aldarate metabolism, Drug metabolism - cytochrome P450, Drug metabolism - other enzymes, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Pentose and glucuronate interconversions, Porphyrin and chlorophyll metabolism, Retinol metabolism, Starch and sucrose metabolism |
| Gene Summary | UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204745 | UGT2B4 (Myc-DDK-tagged)-Human UDP glucuronosyltransferase 2 family, polypeptide B4 (UGT2B4) |
CNY 3,990.00 |
|
| RC204745L1 | Lenti-ORF clone of UGT2B4 (Myc-DDK-tagged)-Human UDP glucuronosyltransferase 2 family, polypeptide B4 (UGT2B4) |
CNY 8,296.00 |
|
| RC204745L2 | Lenti-ORF clone of UGT2B4 (mGFP-tagged)-Human UDP glucuronosyltransferase 2 family, polypeptide B4 (UGT2B4) |
CNY 5,890.00 |
|
| RC204745L3 | Lenti-ORF clone of UGT2B4 (Myc-DDK-tagged)-Human UDP glucuronosyltransferase 2 family, polypeptide B4 (UGT2B4) |
CNY 5,890.00 |
|
| RC204745L4 | Lenti-ORF clone of UGT2B4 (mGFP-tagged)-Human UDP glucuronosyltransferase 2 family, polypeptide B4 (UGT2B4) |
CNY 5,890.00 |
|
| RG204745 | UGT2B4 (tGFP-tagged) - Human UDP glucuronosyltransferase 2 family, polypeptide B4 (UGT2B4) |
CNY 4,370.00 |
