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EPS15R (EPS15L1) (NM_021235) Human Untagged Clone
CAT＃: SC112938
EPS15L1 (untagged)-Human epidermal growth factor receptor pathway substrate 15-like 1 (EPS15L1)
CNY 9,504.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EPS15R |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Restriction Sites | NotI-NotI |
| ACCN | NM_021235 |
| Insert Size | 2710 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_021235.1, NP_067058.1 |
| RefSeq Size | 2854 bp |
| RefSeq ORF | 2595 bp |
| Locus ID | 58513 |
| UniProt ID | Q9UBC2 |
| Domains | EH, EFh |
| Protein Families | Druggable Genome |
| Gene Summary | Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215194 | EPS15L1 (Myc-DDK-tagged)-Human epidermal growth factor receptor pathway substrate 15-like 1 (EPS15L1) |
CNY 9,220.00 |
|
| RC215194L3 | Lenti-ORF clone of EPS15L1 (Myc-DDK-tagged)-Human epidermal growth factor receptor pathway substrate 15-like 1 (EPS15L1) |
CNY 11,120.00 |
|
| RC215194L4 | Lenti-ORF clone of EPS15L1 (mGFP-tagged)-Human epidermal growth factor receptor pathway substrate 15-like 1 (EPS15L1) |
CNY 11,120.00 |
|
| RG215194 | EPS15L1 (tGFP-tagged) - Human epidermal growth factor receptor pathway substrate 15-like 1 (EPS15L1) |
CNY 11,088.00 |
