c-Myc (MYC) (NM_002467) Human Untagged Clone

CAT#: SC112715

MYC (untagged)-Human v-myc myelocytomatosis viral oncogene homolog (avian) (MYC)



  "NM_002467" in other vectors (6)

CNY 5,488.00


货期*
现货

规格
    • 10 ug

Cited in 9 publications.

Product images

经常一起买 (3)
c-Myc (c-Myc ) mouse monoclonal antibody, clone OTI1A6 (formerly 1A6)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms bHLHe39; c-Myc; MRTL; MYCC
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF sequence for NM_002467 edited
ATGCCCCTCAACGTTAGCTTCACCAACAGGAACTATGACCTCGACTACGACTCGGTGCAG
CCGTATTTCTACTGCGACGAGGAGGAGAACTTCTACCAGCAGCAGCAGCAGAGCGAGCTG
CAGCCCCCGGCGCCCAGCGAGGATATCTGGAAGAAATTCGAGCTGCTGCCCACCCCGCCC
CTGTCCCCTAGCCGCCGCTCCGGGCTCTGCTCGCCCTCCTACGTTGCGGTCACACCCTTC
TCCCTTCGGGGAGACAACGACGGCGGTGGCGGGAGCTTCTCCACGGCCGACCAGCTGGAG
ATGGTGACCGAGCTGCTGGGAGGAGACATGGTGAACCAGAGTTTCATCTGCGACCCGGAC
GACGAGACCTTCATCAAAAACATCATCATCCAGGACTGTATGTGGAGCGGCTTCTCGGCC
GCCGCCAAGCTCGTCTCAGAGAAGCTGGCCTCCTACCAGGCTGCGCGCAAAGACAGCGGC
AGCCCGAACCCCGCCCGCGGCCACAGCGTCTGCTCCACCTCCAGCTTGTACCTGCAGGAT
CTGAGCGCCGCCGCCTCAGAGTGCATCGACCCCTCGGTGGTCTTCCCCTACCCTCTCAAC
GACAGCAGCTCGCCCAAGTCCTGCGCCTCGCAAGACTCCAGCGCCTTCTCTCCGTCCTCG
GATTCTCTGCTCTCCTCGACGGAGTCCTCCCCGCAGGGCAGCCCCGAGCCCCTGGTGCTC
CATGAGGAGACACCGCCCACCACCAGCAGCGACTCTGAGGAGGAACAAGAAGATGAGGAA
GAAATCGATGTTGTTTCTGTGGAAAAGAGGCAGGCTCCTGGCAAAAGGTCAGAGTCTGGA
TCACCTTCTGCTGGAGGCCACAGCAAACCTCCTCACAGCCCACTGGTCCTCAAGAGGTGC
CACGTCTCCACACATCAGCACAACTACGCAGCGCCTCCCTCCACTCGGAAGGACTATCCT
GCTGCCAAGAGGGTCAAGTTGGACAGTGTCAGAGTCCTGAGACAGATCAGCAACAACCGA
AAATGCACCAGCCCCAGGTCCTCGGACACCGAGGAGAATGTCAAGAGGCGAACACACAAC
GTCTTGGAGCGCCAGAGGAGGAACGAGCTAAAACGGAGCTTTTTTGCCCTGCGTGACCAG
ATCCCGGAGTTGGAAAACAATGAAAAGGCCCCCAAGGTAGTTATCCTTAAAAAAGCCACA
GCATACATCCTGTCCGTCCAAGCAGAGGAGCAAAAGCTCATTTCTGAAGAGGACTTGTTG
CGGAAACGACGAGAACAGTTGAAACACAAACTTGAACAGCTACGGAACTCTTGTGCGTAA
>OriGene 5' read for NM_002467 unedited
TAGATTTCTGTACACGATTCACTATAGGGCGGCCGCGCAATTCGCACGAGGCGGCTAGGG
TGGAAGAGCCGGGCGAGCAGAGCTGCGCTGCGGGCGTCCTGGGAAGGGAGATCCGGAGCG
AATAGGGGGCTTCGCCTCTGGCCCAGCCCTCCCGCTGATCCCCCAGCCAGCGGTCCGCAA
CCCTTGCCGCATCCACGAAACTTTGCCCATAGCAGCGGGCGGGCACTTTGCACTGGAACT
TACAACACCCGAGCAAGGACGCGACTCTCCCGACGCGGGGAGGCTATTCTGCCCATTTGG
GGACACTTCCCCGCCGCTGCCAGGACCCGCTTCTCTGAAAGGCTCTCCTTGCAGCTGCTT
AGACGCTGGATTTTTTTCGGGTAGTGGAAAACCAGCCTCCCGCGACGATGCCCCTCAACG
TTAGCTTCACCAACAGGAACTATGACCTCGACTACGACTCGGTGCAGCCGTATTTCTACT
GCGACGAGGAGGAGAACTTCTACCAGCAGCAGCAGCCAGAGCGAGCTGCAGCCCCCGGCG
CCCAGCGAGGATATCTGGAAGAAATTCGAGCTGCTGCCCACCCCGCCCCTGTCCCCTAGC
CGCCGCTCCGGGCTCTGCTCGCCCTCCTACGTTGCGGTCACACCCTTCTCCCTTCGGGGA
GACAACGACGGCGGTGGCGGGAGCTTCTCCACGGCCGACCAGCTGTAGATGGTGACCGAG
CTGCTGCGAGGAGACATGCTGAACCACAGTTTCATCTGCGACCCGGACGACGAGACCTTC
ATCAAAAACATCATCATCCAGGACTGTATGTGGGAGCGGCTTTTTCGGCGCCGCCAAGCT
CGTCTCAGAGAGCTGGGCCTCTACAGGGCTGAGCGCAAGACAGAGGNAGACCGAACCCGC
CCGCGGGCCCAGNGTCTGCTCCACCTCCACTTGTACTGCAGTATCTGACGCCGCGCTCAC
ATGCAT
>OriGene 3' read for NM_002467 unedited
TACTTTGGACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTATATTTGC
CAGTTATTTTATTTTTTCTAAAAACAATAGAAAAAATCAACTTTAAAAAGCAAAATGTAC
TTAAATAAAAAAAATTAGGGTTTATAGTACCTATAATACTAGGTACTATATACTAGGATT
GAAATTCTGTGTAACTGCTATAAACGTTTTNATTAAAGTTNTATTTACATTTAATGGCAA
TATTTACAGAGAAACATTGTGTAAATCTTAAAATTTTTTAAAAACAATTCTTAAATACAA
ATCTGTTAAAGAAAAAAAAAAGATGGTAAGCATAAAAAAGTTCTTTTATGCCCAAAGTCC
AATTTGAGGCAGTTTACATTATGGCTAAATCTTTCAGTCTCAAGACTCAGCCAAGGTTGT
GAGGTTGCATTTGATCATGCATTTGAAACAAGTTCATAGGTGATTGCTCANGACATTTCT
GTTAGAAGGAAATCGTTTCCTTACTTTTCCTTACGCACAAAGAGTCCGTAGCTGTTCAAG
TTTGTGTTTCAACTGTTCTCGTCGTTTCCGCAACAAGTCCTCTTCAGAAATGAGCTTTTG
CTCCTCTGCTTGNACGGACAGGATGTATGCTGTGGNCTTTTTAANGGATAACTACCTTNG
GGGGNCCCTTTCATGNTTTCCAACTNCCGGATCTGGTCACGCAGGGCAAAAAAGCTNCGT
TTTAACTCGTTTCTTCTCTGGCGCTNCAAGACGTTGGGTGTTCGCCTCTTGACATTCTCC
TCGGTGTCCGAAGACCTGGGGNCTGTGCATTTTCCGGTGGTGCTGATCTGCTTAAGACTT
TGACACTGTCAACTTGACCCTTTTGCAACAGAAAGTCCTTCGAATGAAGGGAGCCCTGCC
TAATTGCCTAATGTTGGAAACTGGGCACTCTTGAGAACAAGGGCCTTAAGAGGTTTTCTG
GGCCTCACCAAAAGGAACCAACTTTGCCCTTTGCCAAAC
Restriction Sites ECoRI-NOT     
ACCN NM_002467
Insert Size 1365 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_002467.3, NP_002458.2
RefSeq Size 2377 bp
RefSeq ORF 1365 bp
Locus ID 4609
UniProt ID P01106
Domains HLH, Myc_N_term, Myc-LZ
Protein Families Druggable Genome, Embryonic stem cells, Induced pluripotent stem cells, Stem cell - Pluripotency, Stem cell relevant signaling - JAK/STAT signaling pathway, Stem cell relevant signaling - TGFb/BMP signaling pathway, Stem cell relevant signaling - Wnt Signaling pathway, Transcription Factors
Protein Pathways Acute myeloid leukemia, Bladder cancer, Cell cycle, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Jak-STAT signaling pathway, MAPK signaling pathway, Pathways in cancer, Small cell lung cancer, TGF-beta signaling pathway, Thyroid cancer, Wnt signaling pathway
Gene Summary This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (9)

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