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FAM35A (NM_019054) Human Untagged Clone
CAT＃: SC112592
FAM35A (untagged)-Human family with sequence similarity 35, member A (FAM35A)
CNY 6,120.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | bA163M19.1; FAM35A; FAM35A1; RINN2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC112592 sequence for NM_019054 edited (data generated by NextGen Sequencing)
ATGAGTGGAGGATCTCAAGTCCACANNTTTTGGGGTGCTCCAATTGCTCCACTGAAAATC ACAGTATCAGAAGACACAGCTTCTTTAATGTCTGTTGCTGACCCCTGGAAAAAAATTCAG CTTTTATACAGTCAACATTCTTTATATCTGAAGGATGAAAAACAGCACAAAAATCTTGAA AACTATAAAGTCCCAGAATCTATTGGTTCTCCAGATCTTAGTGGTCATTTCTTAGCAAAC TGTATGAATAGACATGTTCATGTGAAAGATGACTTTGTACGTTCTGTTTCTGAAACACAG AATATAGAATCCCAGAAGATTCACTCCTCTAGACTGAGTGATATAACTAGCTCTAATATG CAAATATGTGGATTTAAAAGCACAGTTCCGCATTTCACCGAAGAAGAAAAGTATCAAAAG CTTCTCAGTGAAAATAAAATTAGAGATGAACAGCCTAAACATCAGCCAGATATATGTGGT AAGAACTTTAACACAAATTTGTTTCAGTTGGGCCATAAATGTGCAGCTGTGTTGGATTTG GTTTGTAGTACTGAAAAAATTAATATAGGGCCTGAAGTGGTACAAAGAGAGTGTGTGCCA ACAGAATATCATGAAATACAAAACCAGTGTTTGGGATTATTTTCCTCGAACGCAGTAGAT AAGTCAAGGTCTGAAGCAGCAGTTAGGAAGGTCTCAGACCTTAAAATATCAACTGATACA GAATTTCTCAGTATAATTACCTCCAGCCAGGTTGCTTTTTTAGCTCAAAAGAAAGATAAA AGGCGGAGTCCTGTAAATAAAGGGAATGTAAACATGGAGACTGAACCAAAGGCAAGTTAC GGGGAGATAAGAATACCTGAAGAGAATTCGATTCAGCTTGATGGTTTTACAGAAGCATAT GAAAGTGGACAAAACCAAGCATATTCCCTTGAACTTTTTAGTCCTGTTTGTCCTAAAACA GAAAATAGCCGCATTCACATAAACTCTGATAAAGGTCTTGAAGAACATACAGGATCTCAA GAACTTTTCAGTTCTGAAGATGAACTGCCACCAAATGAGATACGTATTGAGTTGTGTAGC TCAGGAATACTGTGTTCCCAACTAAATACCTTCCACAAAAGTGCTATTAAAAGAAGCTGT ACCTCTGAAGATAAAGTGGGCCAGTCTGAAGCTCTATCTAGAGTCCTTCAAGTAGCTAAG AAAATGAAGTTGATTTCTAATGGAGGAGATTCTGCTGTAGAAATGGATCGGAGAAATGTG TCTGAATTTAAGAGTATTAAAAAAACATCATTAATAAAAAACTGTGATTCTAAAAGCCAG AAGTATAATTGTTTAGTCATGGTGCTATCTCCATGCCATGTGAAGGAAATAAACATAAAA TTCGGACCAAATTCTGGCTCTAAAGTGCCTTTAGCAACAGTTACAGTAATTGATCAATCA GAAACTAAGAAGAAGGTTTTTCTGTGGAGGACTGCAGCATTTTGGGCATTTACAGTGTTT CTTGGAGATATAATTTTACTCACAGATGTTGTTATTCATGAGGACCAATGGATTGGCGAG ACAGTACTACAATCAACATTTAGCAGTCAGTTATTAAATCTTGGGAGTTATTCATCTATT CAGCCTGAAGAATATTCCAGTGTAGTTAGTGAAGTTGTACTTCAAGACTTACTGGCATAT GTGTCCTCAAAACATTCCTACCTCAGAGATCTTCCTCCGAGGCAGCCTCAGAGGGTGAAC AGTATAGACTTTGTAGAATTGGAGCACCTTCAACCTGATGTATTAGTCCACGCAGTACTA AGAGTTGTTGATTTCACTATACTGACAGAGGCAGTATACAGTTATAGAGGACAGAAGCAG AAAAAAGTTATGTTAACAGTGGAACAGGCCCAAGATCAACATTATGCGCTTGTATTATGG GGTCCTGGAGCAGCCTGGTACCCTCAACTTCAAAGGAAAAAAGGAGTGGTTCTGATTAAA GCCCAGATTTCAGAGCTGGCATTTCCTATTACAGCATCTCAGAAGATAGCGCTAAATGCT CACAGTTCTCTGAAGAGTATTTTTTCTTCTCTTCCCAACATCGTATATACTGGCTGTGCA AAATGTGGATTGGAACTAGAAACAGATGAGAACAGGATCTACAAACAATGTTTTAGCTGC TTGCCATTTACTATGAAGAAAATATATTATAGGCCAGCGTTAATGACTGCCATTGATGGA AGACATGATGTTTGTATCCGTGTAGAATCAAAGCTGATAGAGAAGATTCTTCTCAACATT TCTGCAGACTGCCTCAACAGAGTGATAGTTCCTTCCTCAGAGATCACCTATGGGATGGTC GTGGCAGACCTGTTCCACTCCTTGTTGGCAGTCAGCGCAGAACCTTGTGTATTAAAGATT CAGAGCCTTTTTGTGTTAGATGAAAACAGCTATCCATTACAACAAGATTTCTCCCTCCTG GATTTTTATCCTGACATTGTAAAGCATGGAGCCAATGCCCGTCTCTGA Clone variation with respect to NM_019054.2 26 t=>n;27 t=>n;2094 t=>c >OriGene 5' read for NM_019054 unedited
CGTCACATTTGTATACGACTCATATAGGCGGCCGCGCAATCGGCACGAGGCTGACCTGAA TCCTGAATTTTCCTTGATGGTCAAAAGATTAAGATGGAGTCTCACTCTGTTGCCCAGGCT GGAGTGCAATGGCGCGATCTTGGCTCACTGCAACCTCTGCCTTCCGGGTTCAGGCGAGTC TCCTGCTCCAGCCTCCTGAGTAGCTGGGATTACAGAAATCATGAGTGGAGGATCTCAAGT CCACATTTTTGGGGTGCTCCAATTGCTCCACTGAAAATCACAGTATCAGAAGACACAGCT TCTTTAATGTCTGTTGCTGACCCCTGGAAAAAAATTCAGCTTTTATACAGTCAACATTCT TTATATCTGAAGGATGAAAAACAGCACAAAAATCTTGAAAACTATAAAGTCCCAGAATCT ATTGGTTCTCCAGAGCTTAGTGGTCATTTCTTAGCAAACTGTATGAATAGACATGTTCAT GTGAAAGATGACTTTGTACGTTCTGTTTCTGAAACACAGAATATAGAATCCCAGAAGAGT CACTCCTCTAGACTGAGTGATATAACTAGCTCTAATATGCAAATATGTGGATTTAAAAGC ACAGTTCCGCATTTCACCGAAGAAGAAAAGTATCAAAAGCTTCTCAGTGAAAATAAAATT AGAGATGAACAGCCTAAACATCAGCCAGATATATGTGGTAAGAACTTTAACACAAATTTG TTTCAGTTGGGCCATAAATGTGCAGCTGTGTTGCATTTGGTTTGTAGTACTGAAAAAATA ATATAGGGCCCTGAGTGGTACACAGAGAGTGTGTGCCAACAGAATATCATGAGATACANA ACCCAGTGTTTGGGAATATTTTTCTCGAACGCAGTAGATAAGTCAAGGTCTGAAGCAGCA GTTAGGGAAGGTCTCAGACCTTACCAAT >OriGene 3' read for NM_019054 unedited
CCGCGGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCATGGC ATCATGAATTTATTTTCAGGCAATATGATAATCTATTAACACTCAGCATACTCTGAACTT ACAGAATAAGTACCACGCCATACTTCCTCATTAATGACTATCATTTTACATGAGCTTCTT CCACAATCACAATGAGAGAACAGATTGCTACATGTTTGCTGGTAAATGCATTCAGTAAGG CACTCAAATCCTAGACACGAACTAACCACAGAACGCTCTTCCCTGCTTTAATAAATTGAA ACATGATCTCATTTCCTTCATTTTCAATACTTTTTATAAAAAGACACGCTTGTCTTGAAC TTGTCTAAACATAGGTTTATATAAACTAATCCATTATCATTATAGTTATAATCAAGGAAA TGATTTCACATTGACGGTTTTTTAGGTAGGGATAAGCGAAAGCACTGCAGCAGTTTCTGA GGGAATGTCTTCTCTGTGGTTCCCCATACTTAGTACAATGCCTGGAATGTACCAGGGACT AAATACAGTGAACAAATGGGCAAACCTTTAATTCCCAGGGATCTGCTACATATTGCCTTG ACTGGTAGATCATTTCTCCAGGAGAAAGGAAGAAACCAAAAGACAAAAACATTCTTTTTA AACCTCACAGGATTTTCTTAGAAAAAAGTTTTAATTTATATATCTAGTGCAATTCTCTTT GTAAAATATATTCATAAAAAATCAAAGCAAAGCCCTGTATTCATTAATTCAAAAGACAAT CATTCAGTACTTCTCCTTGAAATGCTGCATTTCTTTCTTTGCCTCAAAGAGGGCATTGGC TCATGCTTTACATGTCAGGATAAAAATCAGGAGGAAAAATCTTGTGTATGGAAAACTGTT TCATCTACCAAAAGTTTTGATTCTTATACCAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_019054 |
| Insert Size | 3900 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_019054.1, NP_061927.1 |
| RefSeq Size | 3402 bp |
| RefSeq ORF | 2508 bp |
| Locus ID | 54537 |
| UniProt ID | Q86V20 |
| Gene Summary | Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs) (PubMed:29656893, PubMed:29789392). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection (PubMed:29656893, PubMed:29789392). Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres (PubMed:29656893).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region compared to variant 1. It encodes isoform 2, which is shorter than isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208697 | FAM35A (Myc-DDK-tagged)-Human family with sequence similarity 35, member A (FAM35A) |
CNY 6,120.00 |
|
| RC208697L3 | Lenti ORF clone of Human family with sequence similarity 35, member A (FAM35A), Myc-DDK-tagged |
CNY 8,520.00 |
|
| RC208697L4 | Lenti ORF clone of Human family with sequence similarity 35, member A (FAM35A), mGFP tagged |
CNY 8,520.00 |
|
| RG208697 | FAM35A (tGFP-tagged) - Human family with sequence similarity 35, member A (FAM35A) |
CNY 7,720.00 |
|
| SC322684 | FAM35A (untagged)-Human family with sequence similarity 35, member A (FAM35A) |
CNY 6,120.00 |
