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ICA1 (NM_022307) Human Untagged Clone
CAT＃: SC112522
ICA1 (untagged)-Human islet cell autoantigen 1, 69kDa (ICA1), transcript variant 1
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ICA69; ICAp69 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC112522 sequence for NM_022307 edited (data generated by NextGen Sequencing)
ATGTCAGGACACAAATGCAGTTATCCCTGGGACTTACAGGATCGATATGCTCAAGATAAG TCAGTTGTAAATAAGATGCAACAGAAATATTGGGAGACGAAGCAGGCCTTTATTAAAGCC ACAGGGAAGAAGGAAGATGAACATGTTGTTGCCTCTGACGCGGACCTGGATGCCAAGCTA GAGCTGTTTCATTCAATTCAGAGAACCTGTCTGGACTTATCGAAAGCAATTGTACTCTAT CAAAAGAGGATATGTTTCTTGTCTCAAGAAGAAAACGAACTGGGAAAATTTCTTCGATCC CAAGGTTTCCAAGATAAAACCAGAGCAGGAAAGATGATGCAAGCGACAGGAAAGGCCCTC TGCTTTTCTTCCCAGCAAAGGTTGGCCTTACGAAATCCTTTGTGTCGATTTCACCAAGAA GTGGAGACTTTTCGGCATCGGGCCATCTCAGATACTTGGCTGACGGTGAACCGCATGGAA CAGTGCAGGACGGAATATAGAGGAGCACTATTATGGATGAAGGACGTGTCTCAGGAGCTT GATCCAGACCTCTACAAGCAAATGGAGAAGTTCAGGAAGGTACAAACACAAGTGCGCCTT GCAAAAAAAAACTTTGACAAATTGAAGATGGATGTTTGTCAAAAAGTGGATCTTCTTGGA GCGAGCAGATGCAATCTCTTGTCTCACATGCTAGCAACATACCAGACCACTCTGCTTCAT TTTTGGGAGAAAACTTCTCACACTATGGCAGCCATCCATGAGAGTTTCAAAGGTTATCAA CCATATGAATTTACTACTTTAAAGAGCTTACAAGACCCTATGAAAAAATTAGTTGAGAAA GAAGAGAAGAAGAAAATCAACCAGCAGGAAAGTACAGATGCAGCCGTGCAGGAGCCGAGC CAATTAATTTCATTAGAGGAAGAAAACCAGCGCAAGGAATCCTCTAGTTTTAAGACTGAA GATGGAAAAAGTATTTTATCTGCCTTAGACAAAGGCTCTACACATACTGCATGCTCAGGA CCCATAGATGAACTATTAGACATGAAATCTGAGGAAGGTGCTTGCCTGGGACCAGTGGCA GGGACCCCGGAACCTGAAGGTGCTGACAAAGATGACCTGCTGCTGTTGAGTGAGATCTTC AATGCTTCCTCCTTGGAAGAGGGCGAGTTCAGCAAAGAGTGGGCCGCTGTGTTTGGAGAC GGCCAAGTGAAGGAGCCAGTGCCCACTATGGCCCTGGGAGAGCCAGACCCCAAGGCCCAG ACAGGCTCAGGTTTCCTTCCTTCGCAGCTTTTAGACCAAAATATGAAAGACTTACAGGCC TCGCTACAAGAACCTGCTAAGGCTGCCTCAGACCTGACTGCCTGGTTCAGCCTCTTCGCT GACCTCGACCCACTCTCAAATCCTGATGCTGTTGGGAAAACCGATAAAGAACACGAATTG CTCAATGCATGA Clone variation with respect to NM_022307.2 >OriGene 5' read for NM_022307 unedited
TTTGTATACGACTACTATAGGGCGGCCGCGAATTCGCACGAGGCCCAGGAGATGGGGGTC GAGGAGAGACCCCGGGGAGTAGAGAGAGAGAAACTCACTCCCCGAGTCCCCGACCCTCCC CAAGCAAGAAGAAGAAGAAAACATGTCAGGACACAAATGCAGTTATCCCTGGGACTTACA GGATCGATATGCTCAAGATAAGTCAGTTGTAAATAAGATGCAACAGAAATATTGGGAGAC GAAGCAGGCCTTTATTAAAGCCACAGGGAAGAAGGAAGATGAACATGTTGTTGCCTCTGA CGCGGACCTGGATGCCAAGCTAGAGCTGTTTCATTCAATTCAGAGAACCTGTCTGGACTT ATCGAAAGCAATTGTACTCTATCAAAAGAGGATATGTTTCTTGTCTCAAGAAGAAAACGA ACTGGGAAAATTTCTTCGATCCCAAGGTTTCCAAGATAAAACCAGAGCAGGAAAGATGAT GCAAGCGACAGGAAAGGCCCTCTGCTTTTCTTCCCAGCAAAGGTTGGCCTTACGAAATCC TTTGTGTCGATTTCACCAAGAAGTGGAGACTTTTCGGCATCGGGCCATCTCAGATACTTG GCTGACGGTGAACCGCATGGAACAGTGCAGGACGGAATATAGAGGAGCACTATTATGGAT GAAGGNACGTGTCTCAGGAGCTTGATCCAGACCTCTACAGCAATGGNAGAAGTCANGGAG GTACAACACAAGTGCGCCTTGCAAAANAAAAACTTGACAATGAAGAGGGNATGTTGTCAA AAGTGGATCTTCTTGGACGAGCAGATGCATCTCTGTCTCAATGCTAGCACATACCAGACA CTCTGCTTATTTTTGGGAGAAAACTCTAACTATGGCAGNCATCATGAAAGTTCAAGGGTT ATCACATT >OriGene 3' read for NM_022307 unedited
CGCGGCACGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGCATGTCAAATATCTTTT CTGTTTAATTAAAAAAAAAAAAAAAACAATGTCACAAGAGGCTTCAGAAATACATGCTCT TTGAATTCCAGCCACGAAGAGGACAAAAGGAGACAGGTGGTATCTGCAAATATGGCTGCT TTCCATAGTAAGGTTTGTGCCTTGNGAGAGAAGCCCAGCTCCTCCACCAGTGTNGAGAAC ACGTGGCCCACCAAGCACCTGCTGTGGGGGACCAGTGTCTTTGGTTGGCCAGAGCTCCAT CCAGAGCTTACTGGAAAGGTGGCTTGGCCAGAAAAAGGGAATCTTTCCTACAGCCCTTCC TTCCAGGGGGGACAAAAGGCCTGGGGGCCAAAAAGGAGGCCTTTTAAACTTTGTTTACCC CCCTGGTCGCCCTTTGGGGTTTGAGGAAACCTTTTTAAAACCTACCTTAAAAGAGGCTTT TGGGTTTAAACCTGGAATCTCCGGGGGCCCCCCGGGCCCCCCGGAAACCCCTTTTTGGGT TTTTTTCCCAAAAAAAGGGGGGGCCCCTTAAAAAAAACCTTTTTAAAAAAACTTTGGTTT TTTTTTTTCCCCCCCCGAGAAAAACCCCAAAACCCCTTTTCTCCACAAAAAAAAAAAAAA TTTTTTCCCCATTAAAAGGGGGGGCGGGCACCCTCTTTTTTTTTTTAAAGGGCCGCTTTT TTTATTAATAAAAAAGGGGGGGGGTTTTTTTTTTTTTTTTCCCCCCCCCCAAAAAAATAT TTGTGGGGGGGGGTTTATTGTGTCCCCTCCCCCGAGAGAGAAAAAATTTTTTCTGGGGGN AATATTTTTTTTTTTTTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_022307 |
| Insert Size | 2050 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_022307.1, NP_071682.1 |
| RefSeq Size | 2139 bp |
| RefSeq ORF | 1452 bp |
| Locus ID | 3382 |
| UniProt ID | Q05084 |
| Domains | ICA69 |
| Protein Pathways | Type I diabetes mellitus |
| Gene Summary | This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2013] Transcript Variant: This variant (1, also referred to as IS10) has an alternate first exon and uses an alternate splice junction, both in the 5' UTR, compared to variant 3. Variants 1, 2, 3, 5, and 6 all encode the same isoform (a). |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213136 | ICA1 (Myc-DDK-tagged)-Human islet cell autoantigen 1, 69kDa (ICA1), transcript variant 1 |
CNY 3,656.00 |
|
| RC213136L3 | Lenti ORF clone of Human islet cell autoantigen 1, 69kDa (ICA1), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC213136L4 | Lenti ORF clone of Human islet cell autoantigen 1, 69kDa (ICA1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG213136 | ICA1 (tGFP-tagged) - Human islet cell autoantigen 1, 69kDa (ICA1), transcript variant 1 |
CNY 4,370.00 |
