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FBXL15 (NM_024326) Human Untagged Clone
CAT＃: SC112212
FBXL15 (untagged)-Human F-box and leucine-rich repeat protein 15 (FBXL15)
CNY 2,400.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | Fbl15; FBXO37; JET; PSD |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC112212 sequence for NM_024326 edited (data generated by NextGen Sequencing)
ATGGAGCCACCGATGGAGCCGTCCGGAGGGGAGCAAGAGCCCGGAGCCGTCAGGTTCCTG GACCTGCCCTGGGAAGACGTGCTGCTCCCACACGTCCTGAACCGGGTCCCGCTGCGCCAG CTGCTCCGGCTGCAGCGCGTTAGCCGGGCCTTCCGGTCGCTGGTGCAGCTTCACCTGGCC GGGCTGCGTCGCTTCGATGCCGCGCAGGTGGGTCCGCAGATCCCGCGGGCCGCATTGGCC CGGCTGCTGCGGGATGCCGAGGGGCTGCAGGAGCTGGCACTGGCGCCGTGTCACGAATGG CTGTCAGACGAGGACCTGGTGCCGGTGCTGGCGCGGAATCCGCAGCTGCGGAGTGTGGCG TTGGGCGGCTGCGGGCAACTGAGTCGCCGGGCGCTTGGGGCTTTGGCCGAGGGCTGCCCA CGCCTGCAGCGCCTGTCGCTCGCGCACTGTGACTGGGTGGACGGGCTGGCGCTGCGCGGC CTCGCTGATCGCTGCCCGGCCCTGGAGGAGCTGGATCTCACCGCCTGCCGCCAGCTCAAG GACGAGGCCATCGTGTACCTGGCGCAGAGGCGCGGCGCTGGTCTCCGCAGCCTCTCTCTG GCCGTCAACGCCAACGTGGGGGACGCCGCGGTTCAAGAGTTGGCTCGGAACTGCCCAGAA CTCCACCACCTTGACCTCACCGGCTGCCTCCGCGTCGGAAGCGACGGTGTCAGGACATTG GCCGAGTACTGCCCCGTGCTGCGTTCGCTGCGGGTGCGGCACTGCCACCATGTGGCGGAG TCCAGCCTGAGCCGCTTGCGGAAGCGCGGCGTGGACATCGACGTGGAGCCGCCGCTGCAC CAGGCCCTGGTGCTGCTGCAGGATATGGCGGGCTTCGCACCTTTTGTCAACCTGCAGGTC TGA Clone variation with respect to NM_024326.3 >OriGene 5' read for NM_024326 unedited
ATACGACTCTACTATAGGCGGCCGCGAATTCGGCACGAGGGCCGATGGAGCCACCGATGG AGCCGTCCGGAGGGGAGCAAGAGCCCGGAGCCGTCAGGTTCCTGGACCTGCCCTGGGAAG ACGTGCTGCTCCCACACGTCCTGAACCGGGTCCCGCTGCGCCAGCTGCTCCGGCTGCAGC GCGTTAGCCGGGCCTTCCGGTCGCTGGTGCAGCTTCACCTGGCCGGGCTGCGTCGCTTCG ATGCCGCGCAGGTGGGTCCGCAGATCCCGCGGGCCGCATTGGCCCGGCTGCTGCGGGATG CCGAGGGGCTGCAGGAGCTGGCACTGGCGCCGTGTCACGAATGGCTGTCAGACGAGGACC TGGTGCCGGTGCTGGCGCGGAATCCGCAGCTGCGGAGTGTGGCGTTGGGCGGCTGCGGGC AACTGAGTCGCCGGGCGCTTGGGGCTTTGGCCGAGGGCTGCCCACGCCTGCAGCGCCTGT CGCTCGCGCACTGTGACTGGGTGGACGGGCTGGCGCTGCGCGGCCTCGCTGATCGCTGCC CGGCCCTGGAGGAGCTGGATCTCACCGCCTGCCGCCAGCTCAAGGACGAGGCCATCGTGT ACCTGGCGCAGAGGCGCGGCGCTGGTCTCCGCAGCCTCTCTCTGGCCGTCAACGCCACGT GGGGGACGCCGCGGTTCAAGAGTTGCCTCGGAACTGCCCCAGACTCCACCCACTTGACCT CACCGGCTGCCTTCGCCGTGGAAGCGACGGNGTCAGGACATTGGNCCGAATACTGCCCCC GTGCTGGGTTTCCCTGCGGGNGGCGGGACTGGCACCATGTGGGCGGAATCCAACCTGGAC CGCTTGCGGAAACCGCGGCGTGGAACTTAACATGGAGCCCGCCGTTGACCACAGCCCTGG TGCTGCTGCAAGAAATTGGCGGGCTTCCCACCCTT >OriGene 3' read for NM_024326 unedited
GGACCGCGGCCGCATCTATATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTGGGGGTAA AAAACTCTTTATTTGAAGCTCCAGGGGGGGGCAAGGCACTGGCCTCTCACCAAAGAGTCC TCACAGTTCAATTTCCCTACAGCTCAATGTCAAGCCCCAACCACACAGTCCAACTGTGCT CCGATTGGCAAGCGGGTCAAACCTGCAAGTTGACAAAAGGGGCGAATCCCGCCATATTCT GCAGCAGCACCAAGGCCTGGTGCAGCGGCGGCTCCACGTCGATGTCCACGCCGCGCTTCC GCAAGCGGGTCAAGCTGGACTCCGCCACATGGTGGCAGTGCCGCACCCGCAGCGAACGCA GCACGGGGCAGTACTCGGCCAATGTCCTGACACCGTCGCTTTCGACGCGGAAGCAGCCGG TGAAGTCAAGGTGGTGGAGTTCTGGGCAGTTCCGAACCAACTCTTGAACCGCGGCGTCCC CCACGTTGGCGTTGACGGCCAAAGAGAGGCTGCGGAGACCAACGCCGCGCCTCTGCGCCA GGTACACGATGGCCTCGTTCTTGAACTGGCGGCAGGCGGAGAGATCCAATTTCTCCAGGG CCGGGCAGCGATCATCGAAGCCCCGCATTGCCCATCCCGTTCACCCATTTACAGTGCGCG AGCGACAAGCGCTTCAAGCGTGGGGAACNCCTTGTCCAAACCCCCATACGCCCGGGAATT ATTTGCCCCCATCCGCGCCAAGCCACACTTCGCAAGTTGTGGAATTCGGGCCATCACCAG GACCAAGTTCCTATTCTGAAAATCCTTTTGTGACACAGGGGCCATTGCCAGCTTCTGCAT CCCCTTTGTTTTCCTCACTAATCCTGGCCAATTGGGGCCCGGGGATCTTGGGACCACCTG CGCGGTTTTTAACCTACCCATCCCGTCAAGTGTATCCGTCCCATAACCGGAAGGGCTGCT TAATCTCTCATCCGGATCACTCGCCCCATGTGCCCGGTCTATACGCTGTGAACATTCTTC TT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_024326 |
| Insert Size | 1110 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_024326.2, NP_077302.2 |
| RefSeq Size | 2359 bp |
| RefSeq ORF | 903 bp |
| Locus ID | 79176 |
| UniProt ID | Q9H469 |
| Domains | F-box, LRR_CC |
| Protein Families | Druggable Genome |
| Gene Summary | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206363 | FBXL15 (Myc-DDK-tagged)-Human F-box and leucine-rich repeat protein 15 (FBXL15) |
CNY 2,400.00 |
|
| RC206363L1 | Lenti ORF clone of Human F-box and leucine-rich repeat protein 15 (FBXL15), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC206363L2 | Lenti ORF clone of Human F-box and leucine-rich repeat protein 15 (FBXL15), mGFP tagged |
CNY 5,890.00 |
|
| RC206363L3 | Lenti ORF clone of Human F-box and leucine-rich repeat protein 15 (FBXL15), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206363L4 | Lenti ORF clone of Human F-box and leucine-rich repeat protein 15 (FBXL15), mGFP tagged |
CNY 5,890.00 |
|
| RG206363 | FBXL15 (tGFP-tagged) - Human F-box and leucine-rich repeat protein 15 (FBXL15) |
CNY 4,370.00 |
