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SRD5A3 (NM_024592) Human Untagged Clone
CAT＃: SC112141
SRD5A3 (untagged)-Human steroid 5 alpha-reductase 3 (SRD5A3)
CNY 2,400.00
CNY 2,950.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CDG1P; CDG1Q; KRIZI; SRD5A2L; SRD5A2L1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC112141 sequence for NM_024592 edited (data generated by NextGen Sequencing)
ATGGCTCCCTGGGCGGAGGCCGAGCACTCGGCGCTGAACCCGCTGCGCGCGGTGTGGCTC ACGCTGACCGCCGCCTTCCTGCTGACCCTACTGCTGCAGCTCCTGCCGCCCGGCCTGCTC CCGGGCTGCGCGATCTTCCAGGACCTGATCCGCTATGGGAAAACCAAGTGTGGGGAGCCG TCGCGCCCCGCCGCCTGCCGAGCCTTTGATGTCCCCAAGAGATATTTTTCCCACTTTTAT ATCATCTCAGTGCTGTGGAATGGCTTCCTGCTTTGGTGCCTTACTCAATCTCTGTTCCTG GGAGCACCTTTTCCAAGCTGGCTTCATGGTTTGCTCAGAATTCTCGGGGCGGCACAGTTC CAGGGAGGGGAGCTGGCACTGTCTGCATTCTTAGTGCTAGTATTTCTGTGGCTGCACAGC TTACGAAGACTCTTCGAGTGCCTCTACGTCAGTGTCTTCTCCAATGTCATGATTCACGTC GTGCAGTACTGTTTTGGACTTGTCTATTATGTCCTTGTTGGCCTAACTGTGCTGAGCCAA GTGCCAATGGATGGCAGGAATGCCTACATAACAGGGAAAAATCTATTGATGCAAGCACGG TGGTTCCATATTCTTGGGATGATGATGTTCATCTGGTCATCTGCCCATCAGTATAAGTGC CATGTTATTCTCGGCAATCTCAGGAAAAATAAAGCAGGAGTGGTCATTCACTGTAACCAC AGGATCCCATTTGGAGACTGGTTTGAATATGTTTCTTCCCCTAACTACTTAGCAGAGCTG ATGATCTACGTTTCCATGGCCGTCACCTTTGGGTTCCACAACTTAACTTGGTGGCTAGTG GTGACAAATGTCTTCTTTAATCAGGCCCTGTCTGCCTTTCTCAGCCACCAATTCTACAAA AGCAAATTTGTCTCTTACCCGAAGCATAGGAAAGCTTTCCTACCATTTTTGTTTTAA Clone variation with respect to NM_024592.4 >OriGene 5' read for NM_024592 unedited
GTAACGTCAGAATTTGTATACGACTCACTATAGGCGGCCGCGAATCGGCACGAGGGGCTA GCGGGCGGTGGGGGCGCCAGCAGCGCGGAAGGCGGGCACGCGGGCCATGGCTCCCTGGGC GGAGGCCGAGCACTCGGCGCTGAACCCGCTGCGCGCGGTGTGGCTCACGCTGACCGCCGC CTTCCTGCTGACCCTACTGCTGCAGCTCCTGCCGCCCGGCCTGCTCCCGGGCTGCGCGAT CTTCCAGGACCTGATCCGCTATGGGAAAACCAAGTGTGGGGAGCCGTCGCGCCCCGCCGC CTGCCGAGCCTTTGATGTCCCCAAGAGATATTTTTCCCACTTTTATATCATCTCAGTGCT GTGGAATGGCTTCCTGCTTTGGTGCCTTACTCAATCTCTGTTCCTGGGAGCACCTTTTCC AAGCTGGCTTCATGGTTTGCTCAGAATTCTCGGGGCGGCACAGTTCCAGGGAGGGGAGCT GGCACTGTCTGCATTCTTAGTGCTAGTATTTCTGTGGCTGCACAGCTTACGAAGACTCTT CGAGTGCCTCTACGTCAGTGTCTTCTCCAATGTCATGATTCACGTCGTGCAGTACTGTTT TGGACTTGTCTATTATGTCCTTGTTGGCCTAACTGTGCTGAGCCAAGTGCCAATGGATGG CAGGAATGCCTACATAACAGGGAAAAATCTATTGATGCAAGCACGGTNGGTTCCATATTC TTGGGATGATGATGTTCATCTGGTCATCTGCCCATCAGTATAAGTGCCATGTTATTCTCG GCAATCTCAGGGAAAATAAGCCAGAGTGGTCATTCACTGGTACCACAGGATCCCATTTNG NAGACTGGNTTTGATATGTTTTCTTNCCCTNACTACTTAGCAGAGCTGATGATCTACGTT TCCATGGCCGTCACCTA >OriGene 3' read for NM_024592 unedited
GGCACGCAATTCTAAATCGAGTTTTTTTTTTTTTTTTTTGCAGATTTGACATTATTATTT ATTCTTTGAAGATACTTTGGTAGATTCATTTTCTTGAGTGGCACTGCCATGCTCATTCAT AGAAAACTTGTGGGGTATAGAAATGGAATGGAGAGTTTCAAACAGCTTTGCTGAAACTGT ACTTTGGGCTCCAGACTCTCCTGTCCTTATGCATTGAAACCATCACCTGGCTTGCATTCT TAATGACTGAGGTTAACTTAAAACAAACATGGCAGGAAAGCTTTCCTATGCTTCGGGTAA GAGACAAATTTGCTTTTGTACAATTGGCGGCTGACAAAGGCACACAGGCACTGCTTAAAC AACACATTTGCCACCACTATCCACCCAAGTTAACCCGTGGAACCCACAGGTGACGGCCAT GGAAACGCACATCATCACCTCTGCTAAGCACCTAGGGGAAGAAACATATTCTAACCAATC TCCAAATGGGATCCTGTGGCCACCGTGAATGACCACTCCCCGTTTTATTTTCCCCTGAGA TTGACGACAAATACCCTGGCCCTTATCCCTGTGGGCATATGACCACATGAACCTCATCCT TGCAAGAATATGGGCACCACCGCGCTTGCATAAATACATTTACATCTGTTATGAAAGCAA TACCTGACATTACCATTTGGCACCTTGTCTCAAGTCAGTTTGGCCCCCACGGACCTATTC GACAAGTCCAAATCAGCACCTGCGCGAAGGTGAATCCATGACATCGTGAGAAAAACCCTT GACGTACACGCCCCTCCCAAAAGTCTTTCGCTAGTCCGCGCCACCCACACACAATACTTA CCACCTAACAATGCCCCACTGGGCCCACATACATCTTCCCTTGAAACTGGGGCCGCATCT CGAAAATTCTGTGACCACCCCCTGATACCACCCCTGGTAAAAGCGGCCTCCCACGGACCC ACAATTGGGCCACGCGCCCAAGTTGGAATTCCTTTCCAGGCCTCGAAAGATTAAAAGCGG CTACAAATTCTCTGGCGACACTAN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_024592 |
| Insert Size | 1250 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_024592.1, NP_078868.1 |
| RefSeq Size | 2271 bp |
| RefSeq ORF | 957 bp |
| Locus ID | 79644 |
| UniProt ID | Q9H8P0 |
| Domains | Steroid_dh |
| Protein Families | Transmembrane |
| Protein Pathways | Androgen and estrogen metabolism |
| Gene Summary | The protein encoded by this gene belongs to the steroid 5-alpha reductase family, and polyprenol reductase subfamily. It is involved in the production of androgen 5-alpha-dihydrotestosterone (DHT) from testosterone, and maintenance of the androgen-androgen receptor activation pathway. This protein is also necessary for the conversion of polyprenol into dolichol, which is required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-linked glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type Iq. [provided by RefSeq, Mar 2011] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Hamster SRD5A3 lacks steroid 5α-reductase activity in vitro.
,null,
Steroids
,PubMed ID 25498908
[SRD5A3]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200970 | SRD5A3 (Myc-DDK-tagged)-Human steroid 5 alpha-reductase 3 (SRD5A3) |
CNY 3,600.00 |
|
| RC200970L1 | Lenti ORF clone of Human steroid 5 alpha-reductase 3 (SRD5A3), Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC200970L2 | Lenti ORF clone of Human steroid 5 alpha-reductase 3 (SRD5A3), mGFP tagged |
CNY 5,890.00 |
|
| RC200970L3 | Lenti ORF clone of Human steroid 5 alpha-reductase 3 (SRD5A3), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC200970L4 | Lenti ORF clone of Human steroid 5 alpha-reductase 3 (SRD5A3), mGFP tagged |
CNY 6,000.00 |
|
| RG200970 | SRD5A3 (tGFP-tagged) - Human steroid 5 alpha-reductase 3 (SRD5A3) |
CNY 5,200.00 |
