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MCM10 (NM_018518) Human Untagged Clone
CAT＃: SC111824
MCM10 (untagged)-Human minichromosome maintenance complex component 10 (MCM10), transcript variant 2
CNY 6,408.00
CNY 7,220.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CNA43; DNA43; PRO2249 |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_018518, the custom clone sequence may differ by one or more nucleotides
ATGGATGAGGAGGAAGACAATCTGTCTCTGCTGACCGCACTGCTGGAAGAAAATGAGTCAGCCTTGGATT GTAATTCAGAAGAAAATAACTTCTTGACGCGGGAAAATGGCGAGCCCGACGCATTTGATGAGCTCTTTGA TGCCGACGGCGACGGTGAATCTTATACAGAAGAGGCTGATGATGGAGAAACAGGAGAGACAAGAGACGAA AAGGAAAATCTGGCCACTCTCTTTGGAGATATGGAGGACTTAACAGATGAAGAAGAAGTTCCCGCATCAC AGTCAACTGAAAATAGGGTCCTCCCTGCTCCTGCCCCCAGGCGAGAGAAAACGAATGAAGAGTTGCAAGA GGAATTAAGGAATTTGCAAGAGCAAATGAAGGCCTTACAAGAGCAGCTAAAAGTAACAACAATTAAACAG ACAGCAAGCCCAGCCCGTCTGCAAAAATCCCCTGAGAAGTCTCCCCGGCCACCTCTTAAGGAGAGGAGAG TTCAGAGAATTCAGGAGTCAACATGCTTTTCTGCGGAGCTTGATGTCCCTGCGCTACCAAGAACCAAGAG GGTGGCTCGAACACCAAAGGCTTCACCTCCAGATCCCAAAAGCTCATCTTCAAGGATGACAAGTGCACCC TCCCAACCCCTACAGACGATTTCTCGGAACAAACCTAGTGGGATAACTAGAGGTCAAATTGTGGGGACCC CAGGAAGTTCTGGGGAAACGACTCAACCCATCTGTGTGGAAGCCTTCTCTGGTCTGCGGCTCAGGCGGCC TCGAGTATCCTCCACAGAAATGAACAAGAAAATGACCGGCCGAAAACTGATCAGACTGTCTCAGATCAAG GAAAAGATGGCCAGAGAGAAGCTGGAAGAAATAGATTGGGTGACATTTGGGGTTATATTGAAGAAGGTTA CGCCACAGAGTGTGAATAGTGGAAAAACCTTCAGCATATGGAAACTGAATGATCTTCGTGACCTGACACA ATGTGTGTCCTTGTTCTTATTTGGAGAAGTTCACAAAGCGCTCTGGAAGACGGAGCAGGGGACTGTCGTA GGGATCCTCAATGCCAACCCCATGAAGCCCAAGGATGGTTCAGAGGAGGTGTGTTTATCTATCGATCATC CTCAGAAGGTCTTAATTATGGGTGAAGCTCTTGACCTGGGAACCTGTAAAGCCAAGAAGAAGAATGGAGA GCCGTGCACGCAGACTGTGAATTTGCGTGACTGTGAGTACTGTCAGTACCATGTCCAGGCTCAGTACAAG AAGCTCAGCGCAAAGCGTGCGGATCTGCAGTCCACCTTCTCTGGAGGACGAATTCCAAAGAAGTTTGCCC GCAGAGGCACCAGCCTCAAAGAACGGCTGTGCCAAGATGGCTTTTACTACGGAGGGGTTTCTTCTGCCTC GTATGCAGCTTCAATTGCAGCAGCTGTGGCTCCTAAGAAGAAGATTCAAACCACTCTGAGTAATCTGGTT GTTAAGGGCACAAACTTGATCATCCAGGAAACACGGCAAAAACTCGGAATACCCCAGAAGAGCCTGTCTT GCTCTGAGGAGTTCAAGGAACTGATGGACCTGCCGACGTGTGGAGCCAGGAACTTAAAACAACATTTAGC CAAAGCCACAGCTTCAGGGATTATGGGGAGCCCAAAACCAGCCATCAAGTCCATCTCGGCCTCAGCACTC TTGAAGCAACAGAAGCAGCGGATGTTGGAGATGAGGAGAAGGAAATCAGAAGAAATACAGAAGCGATTTC TGCAGAGCTCAAGTGAAGTTGAGAGCCCAGCTGTGCCATCTTCATCAAGACAGCCCCCTGCTCAGCCTCC ACGGACAGGATCCGAGTTCCCCAGGCTGGAGGGAGCCCCGGCCACAATGACGCCCAAGCTGGGGCGAGGT GTCTTGGAAGGAGATGATGTTCTCTTTTATGATGAGTCACCACCACCAAGACCAAAACTGAGTGCTTTAG CAGAAGCCAAAAAGTTAGCTGCTATCACCAAATTAAGGGCAAAAGGCCAGGTTCTTACAAAAACAAACCC AAACAGCATTAAGAAGAAACAAAAGGACCCTCAGGACATCCTGGAGGTGAAGGAACGTGTAGAAAAAAAC ACCATGTTTTCTTCTCAAGCTGAGGATGAATTGGAGCCTGCCAGGAAAAAAAGGAGAGAACAACTTGCCT ATCTGGAATCTGAGGAATTTCAGAAAATCCTAAAAGCAAAATCAAAACACACAGGCATCCTGAAAGAGGC CGAGGCTGAGATGCAGGAGCGCTACTTTGAGCCACTGGTGAAAAAAGAACAAATGGAAGAAAAGATGAGA AACATCAGAGAAGTGAAGTGCCGTGTCGTGACATGCAAGACGTGCGCCTATACCCACTTCAAGCTGCTGG AGACCTGCGTCAGTGAGCAGCATGAATACCACTGGCATGATGGTGTGAAGAGGTTTTTCAAATGTCCCTG TGGAAACAGAAGCATCTCCTTGGACAGACTCCCGAACAAGCACTGCAGTAACTGTGGCCTCTACAAATGG GAACGGGACGGAATGCTAAAGGAAAAGACTGGTCCAAAGATAGGAGGAGAAACTCTGTTACCAAGAGGAG AAGAACATGCTAAATTTCTGAACAGCCTTAAATAA >OriGene 5' read for NM_018518 unedited
NTTTTACCCCCGCCCGTTGNCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATA AGCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCC GCGAATTCGGCACGAGGCGGCATCGGCCAAGATTCTACATTGCTCATCTGGGCATCTGAG CCTCCTTCGAAGTTTCCTGTCACAACTGTCCTCTTGACAGCATGGATGAGGAGGAAGACA ATCTGTCTCTGCTGACCGCACTGCTGGAAGAAAATGAGTCAGCCTTGGATTGTAATTCAG AAGAAAATAACTTCTTGACGCGGGAAAATGGCGAGCCCGACGCATTTGATGAGCTCTTTG ATGCCGACGGCGACGGTGAATCTTATACAGAAGAGGCTGATGATGGAGAAACAGGAGAGA CAAGAGACGAAAAGGAAAATCTGGCCACTCTCTTTGGAGATATGGAGGACTTAACAGATG AAGAAGAAGTTCCCGCATCACAGTCAACTGAAAATAGGGTCCTCCCTGCTCCTGCCCCCA GGCGAGAGAAAACGAATGAAGAGTTGCAAGAGGAATTAAGGAATTTGCAAGAGCAAATGA AGGCCTTACAAGAGCAGCTAAAAGTAACAACAATTAAACAGACAGCAAGCCCAGCCCGTC TGCAAAAATCCCCTGAGAAGTCTCCCCGGCCACCTCTTAAGGAGAGGAGAGTTCAGAGAT TTCAGGAGTCAACATGCTTTTCTGCGGAGCTTGATGTCCCTGCGCTACCAAAACCAAGAA GGTGGCTCGAACCCCAAAGGCTTCACCTCCCTATCCCAAAGCTCATCTTTCAGGGAGACA AGTGCACCCTCCCACCCCTACAGACGATTTTTCGGACAAACCTATGGGATAACTACAAGG CAAATGTTGGGGACCCCAGCAAT >OriGene 3' read for NM_018518 unedited
NNGGGTACCACTATGNACCCGGNCCGCAANCTANGATCGNATTTTTTTTTTTTTTTTTTG GAAGCAAAGTGGGTGGATTGCTAGTGCTCAGGAGTTTGAGACCAGCCTGAGCAACATGGC AAAACCCCATCTCTACAAAAAATGCAAAAATTAGCTGGGCTTGGTCACGCACGCCTGTAG TCCTAGCTATTTGGGAGACTGAGGTGGGAGGACTGCTTGAGCCCAGGGAAGCCAAGGCTG CAGTGTGCCGCGATCGCACTACTGCACTCCAGCCAGGGTGACATAGTGAGACCCTGTCAT AAAAAATAAAAAAATTAAAAAAAAAATAATATGAGATTTTACATATTTCTATCACAGGGC TCCACAATAATGTAAGAGCAGACAGCCTTCTTTCTCTCTCTATATATAAACTGAAATGCA AAGTGATTCAGTGGCTTGATCAATTTTCAAGAGTAAAACAGAGATAACAGAATTGAATGA AGAAATCTGGCTTTTAATGGCCCTACATAAAGACTATGTGATCATCATTATCTAGATGGG AAAGTTTTATTATTTGTAGAAATCCCCTGCTTAAAAAAACATTTTAAGGAATCCTTAATC CCAACTTCCCGGATTTTCACGATGAAAAAACCGAAGCCCCAAAATTAAACTATTTACCTG GGAGGGGGAAAAAACCCCAATTTTTTTGCCCCTTGGGGGGTGTCATAAAACACTAAAGAT TTTGTTATTGTTAAAAAAGTGAACACCTTTTTTAACCAAAAGATAACGAAACCTCCCCCC CTTTGGTAACCCCCCCCATTTTTGGCCCCTAAACTCTTTGGATGAAATAAGCGCACTCTA CACCCCGTGGTTTTTTATAAAACATATTTACCTTGGGTTCCCCCTTAAGGAGGAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_018518 |
| Insert Size | 3500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_018518.3, NP_060988.3 |
| RefSeq Size | 4532 bp |
| RefSeq ORF | 2625 bp |
| Locus ID | 55388 |
| UniProt ID | Q7L590 |
| Protein Families | Stem cell - Pluripotency |
| Gene Summary | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) encodes the predominant isoform (2). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Human NK cell deficiency as a result of biallelic mutations in MCM10
,Mace, EM;Paust, S;Conte, MI;Baxley, RM;Schmit, M;,
bioRxiv
[MCM10]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210997 | MCM10 (Myc-DDK-tagged)-Human minichromosome maintenance complex component 10 (MCM10), transcript variant 2 |
CNY 6,408.00 |
|
| RC210997L1 | Lenti ORF clone of Human minichromosome maintenance complex component 10 (MCM10), transcript variant 2, Myc-DDK-tagged |
CNY 8,808.00 |
|
| RC210997L2 | Lenti ORF clone of Human minichromosome maintenance complex component 10 (MCM10), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC210997L3 | Lenti ORF clone of Human minichromosome maintenance complex component 10 (MCM10), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210997L4 | Lenti ORF clone of Human minichromosome maintenance complex component 10 (MCM10), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG210997 | MCM10 (tGFP-tagged) - Human minichromosome maintenance complex component 10 (MCM10), transcript variant 2 |
CNY 8,008.00 |
