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VPS41 (NM_014396) Human Untagged Clone
CAT＃: SC111791
VPS41 (untagged)-Human vacuolar protein sorting 41 homolog (S. cerevisiae) (VPS41), transcript variant 1
CNY 6,264.00
| Cited in 5 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HVPS41; hVps41p; HVSP41 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC111791 sequence for NM_014396 edited (data generated by NextGen Sequencing)
ATGGCGGAAGCAGAGGAGCAGGAAACTGGGTCCCTTGAAGAATCTACAGATGAGTCTGAG GAAGAAGAGAGCGAAGAGGAACCCAAGCTGAAGTATGAAAGGCTTTCCAATGGGGTAACT GAAATACTTCAGAAGGATGCAGCTAGCTGCATGACAGTCCATGACAAGTTTTTGGCATTG GGCACACATTATGGCAAGGTTTATTTACTTGATGTCCAGGGGAACATCACTCAGAAGTTT GATGTAAGTCCTGTGAAGATAAATCAGATTAGCTTGGATGAAAGTGGAGAGCACATGGGT GTGTGTTCAGAGGATGGCAAGGTGCAGGTATTTGGACTGTATTCTGGAGAAGAATTTCAC GAGACTTTTGACTGTCCAATTAAAATTATTGCTGTGCACCCACATTTCGTGAGATCCAGT TGCAAGCAGTTTGTGACCGGAGGGAAGAAGCTGCTACTGTTTGAACGGTCTTGGATGAAC AGATGGAAGTCTGCTGTTCTGCATGAAGGGGAAGGGAACATAAGGAGTGTGAAGTGGAGA GGCCATCTGATTGCTTGGGCCAATAATATGGGTGTGAAGATTTTTGACATCATCTCAAAG CAAAGAATCACCAATGTGCCCCGGGATGATATAAGTCTTCGCCCAGACATGTATCCCTGC AGCCTCTGCTGGAAGGACAATGTGACACTGATTATTGGCTGGGGGACTTCTGTCAAGGTG TGCTCAGTGAAGGAACGGCATGCCAGTGAAATGAGGGATTTGCCAAGTCGATATGTTGAA ATAGTGTCTCAGTTTGAAACTGAATTCTACATCAGTGGACTTGCACCTCTCTGTGATCAG CTTGTTGTACTTTCGTATGTAAAGGAGATTTCAGAAAAAACGGAAAGAGAATACTGTGCC AGGCCTAGACTGGACATCATCCAGCCACTTTCTGAGACTTGTGAAGAGATCTCTTCTGAT GCTTTGACAGTCAGAGGCTTTCAGGAGAATGAATGTAGAGATTATCATTTAGAATACTCT GAAGGGGAATCACTTTTTTACATCGTGAGTCCGAGAGATGTTGTAGTGGCCAAGGAACGA GACCAAGATGATCACATTGACTGGCTCCTTGAAAAGAAGAAATATGAAGAAGCATTGATG GCAGCTGAAATTAGCCAAAAAAATATTAAAAGACATAAGATTCTGGATATTGGCTTGGCA TATATAAATCACCTGGTGGAGAGAGGAGACTATGACATAGCAGCACGCAAATGCCAGAAA ATTCTTGGGAAAAATGCAGCACTCTGGGAATATGAAGTTTATAAATTTAAAGAAATTGGA CAGCTTAAGGCTATTAGTCCTTATTTGCCAAGAGGTGATCCAGTTCTGAAACCACTCATC TATGAAATGATCTTACATGAATTTTTGGAGAGTGATTATGAGGGTTTTGCCACATTGATC CGAGAATGGCCTGGAGATCTGTATAATAATTCAGTCATAGTTCAAGCAGTTCGGGATCAT TTGAAGAAAGATAGTCAGAACAAGACTTTACTTAAAACCCTGGCAGAATTGTACACCTAT GATAAGAACTATGGCAATGCTCTGGAAATATACTTAACATTAAGACATAAAGACGTTTTT CAGTTGATCCACAAGCATAATCTTTTCAGTTCTATCAAGGATAAAATTGTTTTATTAATG GATTTTGATTCAGAGAAAGCTGTTGACATGCTTTTGGACAATGAAGATAAAATTTCAATT AAAAAGGTAGTGGAAGAATTGGAAGACAGACCAGAGCTACAGCATGTGTATTTGCATAAG CTTTTCAAGAGAGACCACCATAAGGGGCAGCGTTACCATGAAAAACAGATCAGTCTTTAT GCTGAATATGATCGACCAAACTTACTTCCCTTTCTCCGAGACAGTACCCATTGCCCACTT GAAAAGGCTCTTGAGATCTGTCAACAGAGAAACTTTGTAGAAGAGACAGTTTATCTTCTG AGCCGAATGGGTAATAGCCGAAGTGCCCTGAAGATGATTATGGAGGAATTACATGATGTT GATAAAGCAATCGAATTTGCCAAGGAGCAAGATGATGGAGAGCTGTGGGAAGATTTGATT TTATATTCCATTGACAAACCACCATTTATTACTGGCTTGTTAAACAACATTGGCACACAT GTTGACCCAATTCTACTGATTCACCGTATTAAGGAAGGAATGGAGATCCCCAATTTGAGA GATTCCTTGGTTAAAATTCTGCAAGACTACAATTTGCAAATTCTGCTTCGTGAAGGCTGC AAGAAGATTCTCGTAGCTGACTCTTTGTCCTTACTGAAGAAAATGCACCGAACTCAAATG AAAGGTGTTCTTGTTGATGAGGAGAACATCTGTGAGTCGTGCCTTTCCCCTATTCTTCCA TCAGATGCAGCTAAGCCCTTCAGCGTGGTGGTCTTCCATTGCCGGCACATGTTCCACAAG GAGTGCCTGCCCATGCCCAGCATGAACTCTGCTGCACAGTTCTGCAACATCTGCAGTGCT AAGAACCGTGGACCAGGAAGTGCAATTTTGGAGATGAAAAAATAG Clone variation with respect to NM_014396.3 378 c=>a;1563 c=>t >OriGene 5' read for NM_014396 unedited
ATTCGGATTTGTAACCGACTTACTATAGGCGGCCGCGCAATTCGCACGAGGGCGCCATGG CGGAAGCAGAGGAGCAGGAAACTGGGTCCCTTGAAGAATCTACAGATGAGTCTGAGGAAG AAGAGAGCGAAGAGGAACCCAAGCTGAAGTATGAAAGGCTTTCCAATGGGGTAACTGAAA TACTTCAGAAGGATGCAGCTAGCTGCATGACATTCCATGACAAGTTTTTGGCATTGGGCA CACATTATGGCAAGGTTTATTTACTTGATGTCCAGGGGAACATCACTCAGAAGTTTGATG TAAGTCCTGTGAAGATAAATCAGATTAGCTTGGATGAAAGTGGAGAGCACATGGGTGTGT GTTCAGAGGATGGCAAGGTGCAGGTATTTGGACTGTATTCTGGAGAAGAATTTCACGAGA CTTTTGACTGTCCAATTAAAATTATTGCTGTGCACCCACATTTCGTGAGATCCAGTTGCA AGCAGTTTGTGACCGGAGGGAAGAAGCTGCTACTGTTTGAACGGTCTTGGATGAACAGAT GGAAGTCTGCTGTTCTGCATGAAGGGGAAGGGAACATAAGGAGTGTGAAGTGGAGAGGCC ATCTGATTGCTTGGGCCAATAATATGGGTGTGAAGATTTTTGACATCATCTCANAGCAAA GAATCACCAATGTGCCCCGGGATGATATAAGTCTTCGCCCAGACATGTATCCCTGCAGCC TCTGCTGGAANGGACATGTGACACTGATTATTGGCTGGGGGACTTCTGTCAAGGTGTGCT CAGTGAAGGAACCGCATGCCAGTGAAATGAGGGATTTGCCAAGTCGATATGTTGAAATAG TGTCTCAGTTTGAAACTGAATTCTACATCAGTGGACTTGCACCTCTCTGTGATCAGCTTG GTGTACTTTT >OriGene 3' read for NM_014396 unedited
CCGCAATCTAGAGTCGAGNTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTACAATGGAAAAAAGCTAACATTTATTCAATCAACAAATGCTGAGTGTCCCCCATG GCCAAATACTTTTTGACAGTCGTCACAGCACACAAAACATGTGATTAGTAAACATAATGG GGCAGGACATCACCCTGCTAATGTTATTCCCAGGGGTCATCAAATGAGGGACAATTTGTA CAATGTTTCATTAAATGCCTATTTAAAGGATAACCATAGTTGATGACCCAAAAAAAAGCC AAACCCAAAATGCAAAAATCGTACCCAGCAAAGCACGTGGAAACAACGTCCAAGTTGCAG GTAACAGCTTGCAGGATAACCACAGTTGGCGACCCTTTCAGGCAGCTGGGAAAATTCTCA GTTGCCCATTTTATGGTTAAAGGGTTTTACTAAGGGCTAAAAAATTCATTTCTAACTCCT AAACTTATGTTTCCATTACTATATAAAGAAGGAGCCAAACAAATAAATAACAAAATATTC ACTATGGACCCCAAAATTTCAAGGCATGAAGAGAGCCCCAAATTCTCTGTGAACTGCAAA GAGAAACCTTTAGTCCAGGAATAGATGAAGAAATTGTTCTTGAGTATAATATAAACATAA ACAAATCTCCTTAACACACGAGTGTCAACAAATGCTTTTGTTGTTGCAAAAACAGTCTCA AAAAGAGTGGGGACAAGGACACTGACAGGAGAAATGAGCTATTTTTCACTCCAAATTGCA CTTCCTGGCCACGGTTTTAACCTGCAAAGTCGCAAACTGTGCAAAAATTATGCTGGGCTG CCAGCACTCTTGGGGCCTGGCCGGCATGAAACCCCCCCGCTAAGGCTTAACTGCTTGGGG AAAATGGGGAAGCCCACTCAAAGTTTCCTTTCAAAAACCACTATTTAGTGCGGCTTTCTC CAAAGCAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_014396 |
| Insert Size | 3410 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_014396.2, NP_055211.1 |
| RefSeq Size | 4914 bp |
| RefSeq ORF | 2565 bp |
| Locus ID | 27072 |
| UniProt ID | P49754 |
| Domains | Clathrin |
| Protein Families | Druggable Genome |
| Gene Summary | Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human ortholog of yeast Vps41 protein which is also conserved in Drosophila, tomato, and Arabidopsis. Expression studies in yeast and human indicate that this protein may be involved in the formation and fusion of transport vesicles from the Golgi. Several transcript variants encoding different isoforms have been described for this gene, however, the full-length nature of not all is known. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) encodes the full-length isoform (1). |
Citations (5)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells
,Stephanie A. Zlatic, Karine Tornieri, Steven W. L’Hernault, and Victor Faundez,
Mol. Biol. Cell, May 2011; 22: 1699 - 1715
[VPS41]
|
|
Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells
,null,
Molecular Biology of the Cell
,PubMed ID 21411634
[VPS41]
|
|
SPE-39 Family Proteins Interact with the HOPS Complex and Function in Lysosomal Delivery
,Guang-dan Zhu, Gloria Salazar, Stephanie A. Zlatic, Babar Fiza, Michele M. Doucette, Craig J. Heilman, Allan I. Levey, Victor Faundez, and Steven W. L'Hernault,
Mol. Biol. Cell, Feb 2009; 20: 1223 - 1240.
[VPS41]
|
|
SPE-39 Family Proteins Interact with the HOPS Complex and Function in Lysosomal Delivery
,null,
Molecular Biology of the Cell
,PubMed ID 19109425
[VPS41]
|
|
Hermansky-Pudlak Syndrome Protein Complexes Associate with Phosphatidylinositol 4-Kinase Type II in Neuronal and Non-neuronal Cells
,Gloria Salazar, Stephanie Zlatic, Branch Craige, Andrew A. Peden, Jan Pohl, and Victor Faundez,
J. Biol. Chem., Jan 2009; 284: 1790 - 1802.
[VPS41]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207267 | VPS41 (Myc-DDK-tagged)-Human vacuolar protein sorting 41 homolog (S. cerevisiae) (VPS41), transcript variant 1 |
CNY 6,256.00 |
|
| RC207267L1 | Lenti ORF clone of Human vacuolar protein sorting 41 homolog (S. cerevisiae) (VPS41), transcript variant 1, Myc-DDK-tagged |
CNY 8,656.00 |
|
| RC207267L2 | Lenti ORF clone of Human vacuolar protein sorting 41 homolog (S. cerevisiae) (VPS41), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC207267L3 | Lenti ORF clone of Human vacuolar protein sorting 41 homolog (S. cerevisiae) (VPS41), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC207267L4 | Lenti ORF clone of Human vacuolar protein sorting 41 homolog (S. cerevisiae) (VPS41), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG207267 | VPS41 (tGFP-tagged) - Human vacuolar protein sorting 41 homolog (S. cerevisiae) (VPS41), transcript variant 1 |
CNY 7,856.00 |
