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DUSP10 (NM_007207) Human Untagged Clone
CAT＃: SC111766
DUSP10 (untagged)-Human dual specificity phosphatase 10 (DUSP10), transcript variant 1
CNY 2,950.00
| Cited in 3 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MKP-5; MKP5 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC111766 sequence for NM_007207 edited (data generated by NextGen Sequencing)
ATGCCTCCGTCTCCTTTAGACGACAGGGTAGTAGTGGCACTATCTAGGCCCGTCCGACCT CAGGATCTCAACCTTTGTTTAGACTCTAGTTACCTTGGCTCTGCCAACCCAGGCAGTAAC AGCCACCCTCCTGTCATCGCCACCACCGTTGTGTCCCTCAAGGCTGCGAATCTGACGTAT ATGCCCTCATCCAGCGGCTCTGCCCGCTCGCTGAATTGTGGATGCAGCAGTGCCAGCTGC TGCACTGTGGCAACCTACGACAAGGACAATCAGGCCCAAACCCAAGCCATTGCCGCTGGC ACCACCACCACTGCCATCGGAACCTCTACCACCTGCCCTGCTAACCAGATGGTCAACAAT AATGAGAATACAGGCTCTCTAAGTCCATCAAGTGGGGTGGGCAGCCCTGTGTCAGGGACC CCCAAGCAGCTAGCCAGCATCAAAATAATCTACCCCAATGACTTGGCAAAGAAGATGACC AAATGCAGCAAGAGTCACCTGCCGAGTCAGGGCCCTGTCATCATTGACTGCAGGCCCTTC ATGGAGTACAACAAGAGTCACATCCAAGGAGCTGTCCACATTAACTGTGCCGATAAGATC AGCCGGCGGAGACTGCAGCAGGGCAAGATCACTGTCCTAGACTTGATTTCCTGTAGGGAA GGCAAGGACTCTTTCAAGAGGATCTTTTCCAAAGAAATTATAGTTTATGATGAGAATACC AATGAACCAAGCCGAGTGATGCCCTCCCAGCCACTTCACATAGTCCTCGAGTCCCTGAAG AGAGAAGGCAAAGAACCTCTGGTGTTGAAAGGTGGACTTAGTAGTTTTAAGCAGAACCAT GAAAACCTCTGTGACAACTCCCTCCAGCTCCAAGAGTGCCGGGAGGTGGGGGGCGGCGCA TCCGCGGCCTCGAGCTTGCTACCTCAGCCCATCCCCACCACCCCTGACATCGAGAACGCT GAGCTCACCCCCATCTTGCCCTTCCTGTTCCTTGGCAATGAGCAGGATGCTCAGGACCTG GACACCATGCAGCGGCTGAACATCGGCTACGTCATCAACGTCACCACTCATCTTCCCCTC TACCACTATGAGAAAGGCCTGTTCAACTACAAGCGGCTGCCAGCCACTGACAGCAACAAG CAGAACCTGCGGCAGTACTTTGAAGAGGCTTTTGAGTTCATTGAGGAAGCTCACCAGTGT GGGAAGGGGCTTCTCATCCACTGCCAGGCTGGGGTGTCCCGCTCCGCCACCATCGTCATC GCTTACTTGATGAAGCACACTCGGATGACCATGACTGATGCTTATAAATTTGTCAAAGGC AAACGACCAATTATCTCCCCAAACCTTAACTTCATGGGGCAGTTGCTAGAGTTCGAGGAA GACCTAAACAACGGTGTGACACCGAGAATCCTTACACCAAAGCTGATGGGCGTGGAGACG GTTGTGTGA Clone variation with respect to NM_007207.4 >OriGene 5' read for NM_007207 unedited
GTTAGATTTTATACACTATTAGGCGGCCGCGATTCGCCGAGGACAATGAACCGATGATGG GGGCTGAATGTGCGAGTCCATAGCTGAAGAGGAGCGCCAGATGGTGGAGGAATACACTTA TTTATGAAACTGTCTTGAGTTCTTCTTGAATTGCCAGTTTTCAGCCTCCTCATGCCTCCG TCTCCTTTAGACGACAGGGTAGTAGTGGCACTATCTAGGCCCGTCCGACCTCAGGATCTC AACCTTTGTTTAGACTCTAGTTACCTTGGCTCTGCCAACCCAGGCAGTAACAGCCACCCT CCTGTCATCGCCACCACCGTTGTGTCCCTCAAGGCTGCGAATCTGACGTATATGCCCTCA TCCAGCGGCTCTGCCCGCTCGCTGAATTGTGGATGCAGCAGTGCCAGCTGCTGCACTGTG GCAACCTACGACAAGGACAATCAGGCCCAAACCCAAGCCATTGCCGCTGGCACCACCACC ACTGCCATCGGAACCTCTACCACCTGCCCTGCTAACCAGATGGTCAACAATAATGAGAAT ACAGGCTCTCTAAGTCCATCAAGTGGGGTGGGCAGCCCTGTGTCAGGGACCCCCAAGCAG CTAGCCAGCATCAAAATAATCTACCCCAATGACTTGGCAAAGAAGATGACCAAATGCAGC AAGAGTCACCTGCCGAGTCANGGCCCTGTCATCATTGACTGCAGGCCCTTCATGGAGTAC AACAAGAGTCACATCCAAGGAGCTGTCCACATTAACTGTGCCGNATAGATCAGCCGGCGG AGACTGCAGCAGGGCAAGATCACTGTCCTAGACTTGATTTCCTGTAGGGAAAGGCAGGAC TCTTTCAAGAGATCTTTTCAAAGAAATTATAGTTATGATGAGATACCCATGACCAAGCCG ATGATGCCCTT >OriGene 3' read for NM_007207 unedited
TCTATGGACCGCGGCCCGCATTTCTAAAGTCGAGTTTTTTTTTTTTTTTTTTGCGAAAAA ATTTTTAAATAAATTTTTTTTTCTTACATTCTGATATACATATGTAACAAGGTTTATGGC ACTGTAACCAGAATCAAATCAGAAAAAAAAAAAAAAAGGAAAAAGGTGGGAAGGAAAGTA TTTGATATATTGTTGAATTCCTTTCTATCTCCAAGCTGGCAAATTTGCACTATTTGTCTA TCATTCAGCTGCCAGCTCTAACTTGTTTGCACACTTAAAACATCATATTATTGCACAAGA AGCCAGTGAAGGCATATAATGGTCAGTTCCTCACTATTTCAAAAAAAATCTCTTAAACCC AGAGAAGGAAAAAAAAAAAAAAAATCCAGAGCATGAAACACACAAAATCAAAGGTATCCT TTTTCTCCTTAAAGAATGCCTGAAGGATTCTTAAACCACTTAAGCTGCCCTGATCTTCTC TTTGCACCAGTGAGCACAACAGGGCTTGGTTTGGTTGGGTTTTTGTTTTCTGTGTGGACA GCCCAGGTTGATCCCAGGCCTTGGAGATTCAATGTCTTTTCTATTTACTTTTGGTTCTTT TTAATTGGTTTAAAGTGTGTAGTATCTTCGGTCTATGAACCTGCACAGACTATTTAGTCA TAAACTCTACAAATAGCTTAAAAGGAAAAGGGGGAGAAACAAGTTGTATTATATTTTTAT TGTTGGCTTAAAAAATTACTTCTTTAACCTCCTTAATTTGNCAGTTTNGTGGGAAGTGAA TCTCAATGGCATCAAAAGCTATAGTCTTCCTACACTTGTTAANNATNAAGTGTTAAANNC AGTTTGTTCCATTTCACAACTTACTCCCCACCTCANNAAAAAAAGAAAGAAAAAACCCGA ACCCTCCTCCCTCCTCATGCCTCCTAATGGAGAGCAGCATCCTTTTCATTNCAGACATTG TNACACAACGTNNTCACGCCATAGCTTTGTTGAAGGATT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_007207 |
| Insert Size | 2750 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_007207.3, NP_009138.1 |
| RefSeq Size | 2619 bp |
| RefSeq ORF | 1449 bp |
| Locus ID | 11221 |
| UniProt ID | Q9Y6W6 |
| Domains | DSPc, RHOD |
| Protein Families | Druggable Genome, Phosphatase |
| Protein Pathways | MAPK signaling pathway |
| Gene Summary | Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] Transcript Variant: This variant (1) represents the longest transcript and encodes the functional protein. |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
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DUSP10 Is a Regulator of YAP1 Activity Promoting Cell Proliferation and Colorectal Cancer Progression
,Jiménez-Martínez, M;Ostalé, CM;van der Burg, LR;Galán-Martínez, J;Hardwick, JCH;López-Pérez, R;Hawinkels, LJAC;Stamatakis, K;Fresno, M;,
Cancers (Basel) 2019
,PubMed ID 31717606
[DUSP10]
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Oxidative stress-induced JNK activation contributes to proinflammatory phenotype of aging diabetic mesangial cells
,Jin Wu, Changlin Mei, Helen Vlassara, Gary E. Striker, and Feng Zheng,
Am J Physiol Renal Physiol, Dec 2009; 297: F1622 - F1631
[DUSP10]
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Oxidative Stress Induced JNK Activation Contributes to Proinflammatory Phenotype of Aging Diabetic Mesangial Cells
,Jin Wu, Changlin Mei, Helen Vlassara, Gary E Striker, and Feng Zheng,
Am J Physiol Renal Physiol, Sep 2009; 10.1152/ajprenal.00078.2009
[DUSP10]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206760 | DUSP10 (Myc-DDK-tagged)-Human dual specificity phosphatase 10 (DUSP10), transcript variant 1 |
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| RC206760L1 | Lenti ORF clone of Human dual specificity phosphatase 10 (DUSP10), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
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| RC206760L2 | Lenti ORF clone of Human dual specificity phosphatase 10 (DUSP10), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC206760L3 | Lenti ORF clone of Human dual specificity phosphatase 10 (DUSP10), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206760L4 | Lenti ORF clone of Human dual specificity phosphatase 10 (DUSP10), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG206760 | DUSP10 (tGFP-tagged) - Human dual specificity phosphatase 10 (DUSP10), transcript variant 1 |
CNY 4,370.00 |
|
| SC322594 | DUSP10 (untagged)-Human dual specificity phosphatase 10 (DUSP10), transcript variant 1 |
CNY 2,950.00 |
