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IMP3 (IGF2BP3) (NM_006547) Human Untagged Clone
CAT＃: SC111161
IGF2BP3 (untagged)-Human insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3)
CNY 6,480.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CT98; IMP-3; IMP3; KOC; KOC1; VICKZ3 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC111161 sequence for NM_006547 edited (data generated by NextGen Sequencing)
ATGAACAAACTGTATATCGGAAACCTCAGCGAGAACGCCGCCCCCTCGGACCTAGAAAGT ATCTTCAAGGACGCCAAGATCCCGGTGTCGGGACCCTTCCTGGTGAAGACTGGCTACGCG TTCGTGGACTGCCCGGACGAGAGCTGGGCCCTCAAGGCCATCGAGGCGCTTTCAGGTAAA ATAGAACTGCACGGGAAACCCATAGAAGTTGAGCACTCGGTCCCAAAAAGGCAAAGGATT CGGAAACTTCAGATACGAAATATCCCGCCTCATTTACAGTGGGAGGTGCTGGATAGTTTA CTAGTCCAGTATGGAGTGGTGGAGAGCTGTGAGCAAGTGAACACTGACTCGGAAACTGCA GTTGTAAATGTAACCTATTCCAGTAAGGACCAAGCTAGACAAGCACTAGACAAACTGAAT GGATTTCAGTTAGAGAATTTCACCTTGAAAGTAGCCTATATCCCTGATGAAATGGCCGCC CAGCAAAACCCCTTGCAGCAGCCCCGAGGTCGCCGGGGGCTTGGGCAGAGGGGCTCCTCA AGGCAGGGGTCTCCAGGATCCGTATCCAAGCAGAAACCATGTGATTTGCCTCTGCGCCTG CTGGTTCCCACCCAATTTGTTGGAGCCATCATAGGAAAAGAAGGTGCCACCATTCGGAAC ATCACCAAACAGACCCAGTCTAAAATCGATGTCCACCGTAAAGAAAATGCGGGGGCTGCT GAGAAGTCGATTACTATCCTCTCTACTCCTGAAGGCACCTCTGCGGCTTGTAAGTCTATT CTGGAGATTATGCATAAGGAAGCTCAAGATATAAAATTCACAGAAGAGATCCCCTTGAAG ATTTTAGCTCATAATAACTTTGTTGGACGTCTTATTGGTAAAGAAGGAAGAAATCTTAAA AAAATTGAGCAAGACACAGACACTAAAATCACGATATCTCCATTGCAGGAATTGACGCTG TATAATCCAGAACGCACTATTACAGTTAAAGGCAATGTTGAGACATGTGCCAAAGCTGAG GAGGAGATCATGAAGAAAATCAGGGAGTCTTATGAAAATGATATTGCTTCTATGAATCTT CAAGCACATTTAATTCCTGGATTAAATCTGAACGCCTTGGGTCTGTTCCCACCCACTTCA GGGATGCCACCTCCCACCTCAGGGCCCCCTTCAGCCATGACTCCTCCCTACCCGCAGTTT GAGCAATCAGAAACGGAGACTGTTCATCTGTTTATCCCAGCTCTATCAGTCGGTGCCATC ATCGGCAAGCAGGGCCAGCACATCAAGCAGCTTTCTCGCTTTGCTGGAGCTTCAATTAAG ATTGCTCCAGCAGAAGCACCAGATGCTAAAGTGAGGATGGTGATTATCACTGGACCACCA GAGGCTCAGTTCAAGGCTCAGGGAAGAATTTATGGAAAAATTAAAGAAGAAAACTTTGTT AGTCCTAAAGAAGAGGTGAAACTTGAAGCTCATATCAGAGTGCCATCCTTTGCTGCTGGC AGAGTTATTGGAAAAGGAGGCAAAACGGTGAATGAACTTCAGAATTTGTCAAGTGCAGAA GTTGTTGTCCCTCGTGACCAGACACCTGATGAGAATGACCAAGTGGTTGTCAAAATAACT GGTCACTTCTATGCTTGCCAGGTTGCCCAGAGAAAAATTCAGGAAATTCTGACTCAGGTA AAGCAGCACCAACAACAGAAGGCTCTGCAAAGTGGACCACCTCAGTCAAGACGGAAGTAA Clone variation with respect to NM_006547.2 1332 g=>a >OriGene 5' read for NM_006547 unedited
TACCATTTATGTATACGACTCACTATAGGGCGGCCGCGACATTCGCACGAGGAGACTGGT GGATGCGTTTGGGTTGTAGCTAGGCTTTTTCTTTTCTTTCTCTTTTAAAACACATCTAGA CAAGGAAAAAACAAGCCTCGGATCTGATTTTTCACTCCTCGTTCTTGTGCTTGGTTCTTA CTGTGTTTGTGTATTTTAAAGGCGAGAAGACGAGGGGAACAAAACCAGCTGGATCCATCC ATCACCGTGGGTGGTTTTAATTTTTCGTTTTTTCTCGTTATTTTTTTTTAAACAACCACT CTTCACAATGAACAAACTGTATATCGGAAACCTCAGCGAGAACGCCGCCCCCTCGGACCT AGAAAGTATCTTCAAGGACGCCAAGATCCCGGTGTCGGGACCCTTCCTGGTGAAGACTGG CTACGCGTTCGTGGACTGCCCGGACGAGAGCTGGGCCCTCAAGGCCATCGAGGCGCTTTC AGGTAAAATAGAACTGCACGGGAAACCCATAGAAGTTGAGCACTCGGTCCCAAAAAGGCA AAGGATTCGGAAACTTCAGATACGAAATATCCCGCCTCATTTACAGTGGGAGGTGCTGGA TAGTTTACTAGTCCAGTATGGAGTGGTGGAGAGCTGTGAGCCAGTGAACACTGACTCGGA AACTGCAGTTGTAAATGTAACCTATTCCAGTAAGGACCAAGCTAGACAAGCCCTAGACAA ACTGAATGGATTTCAGNTAGAGGATTTCACCCTGAAAGTAGCCTATATCCCTGATGAAAT GGGCGGCCAGCAAAACCCCTTGCAGGAGCCCCGAGTTCGCCGGGGGCTTTGGCAGAAGGG CTCCTAAAGGCAGGGGCTTCAGGATCCGTATCCAGCACAACCCGGTGATTGCCTTGCGCC TGCTGGTTCCCCCCCTTGGTGGAGCCTCTAGAAAAGCAGGGCCCCT >OriGene 3' read for NM_006547 unedited
AGCTCTGGACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTGCACCT AAATGATGAAAAAATTTAGTCTGCGTCAAGGTATCTGAGAAAATGAAGCTGCATTTGGGG CACATTATACATGAGGAATGATCCATATATGGTGAGTACAAAACTCAATTATAGAATTAT TTCTTAGCTAGTACCAGATACTCCAAATTACAAATGCTTAAGTAAAAGTAAAATATGATT TGCCATACTAAAAGGCTAGAAGTGAAATATGACAGAATTTAAACCAGCAGATATAAATGC AGCACCTATGTGTATATTTTTAAAAAATCAAATATTGGGGAAAAAAATCAAATACTGAGA AAAGCTCTGGCCTTAAACACATCTTACCTGAAATCCAACCAGAAAGCCAGTCCATGATTT TAGCAATTTTAATTCATTGTATGAAAAAAAAATCATGAATGCTAGGAGAATCCAGTGACA AAAAGGGCACTTTTTTGGTTAAAACTACAAAAGAAACTTGTTTTCAGAGAACATTAAGGA AAACACTTTAAATCATTTTCAAAATGTCTAATTGATCTTCAGAAAAACATCTAGTCTGTA TAGAAATTCATCTTGAAATAAGAATGAGGCAGTGATTCTTTTTTTAAAGGGTTATATATA TGTCCTTTAGATCAGTGTAACATGACTGTGATCATCTTACANACAAAACTCANAAAATCA ATTCAGAGAGCAGCGTGGCCTTGGAGACCACCCACACCCAACACAATTGTACGTACTGGG CTTTGCTGTCAGGAGTGAGCANATGAGTTCGTATCNAAAGTCATATGTTTTCACAGTCAT TCAAATTATATCCCANAAACTTTNNCTGGATCTCTATCTTTTGACTTTNTTTTCAAGAAA CTGATGACAGTATCAGAAATCTGTATACTTTNACTACTAGGNNGAGNCTAATTTTTTTTT AANTNATCANGCT |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_006547 |
| Insert Size | 2050 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006547.2, NP_006538.2 |
| RefSeq Size | 4168 bp |
| RefSeq ORF | 1740 bp |
| Locus ID | 10643 |
| UniProt ID | O00425 |
| Domains | RRM, KH |
| Gene Summary | The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition
,Moldovan, JB;Moran, JV;,
PLoS Genet.
,PubMed ID 25951186
[IGF2BP3]
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| RC209597L4 | Lenti ORF clone of Human insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3), mGFP tagged |
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| RG209597 | IGF2BP3 (tGFP-tagged) - Human insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) |
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| SC324059 | IGF2BP3 (untagged)-Human insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) |
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