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DR5 (TNFRSF10B) (NM_003842) Human Untagged Clone
CAT＃: SC111085
TNFRSF10B (untagged)-Human tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 1
CNY 3,656.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9 |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003842 edited
GCGCTTGCGGAGGATTGCGTTGACGAGACTCTTATTTATTGTCACCAACCTGTGGTGGAA TTTGCAGTTGCACATTGGATCTGATTCGCCCCGCCCCGAATGACGCCTGCCCGGAGGCAG TGAAAGTACAGCCGCGCCGCCCCAAGTCAGCCTGGACACATAAATCAGCACGCGGCCGGA GAACCCCGCAATCTCTGCGCCCACAAAATACACCGACGATGCCCGATCTACTTTAAGGGC TGAAACCCACGGGCCTGAGAGACTATAAGAGCGTTCCCTACCGCCATGGAACAACGGGGA CAGAACGCCCCGGCCGCTTCGGGGGCCCGGAAAAGGCACGGCCCAGGACCCAGGGAGGCG CGGGGAGCCAGGCCTGGGCTCCGGGTCCCCAAGACCCTTGTGCTCGTTGTCGCCGCGGTC CTGCTGTTGGTCTCAGCTGAGTCTGCTCTGATCACCCAACAAGACCTAGCTCCCCAGCAG AGAGCGGCCCCACAACAAAAGAGGTCCAGCCCCTCAGAGGGATTGTGTCCACCTGGACAC CATATCTCAGAAGACGGTAGAGATTGCATCTCCTGCAAATATGGACAGGACTATAGCACT CACTGGAATGACCTCCTTTTCTGCTTGCGCTGCACCAGGTGTGATTCAGGTGAAGTGGAG CTAAGTCCCTGCACCACGACCAGAAACACAGTGTGTCAGTGCGAAGAAGGCACCTTCCGG GAAGAAGATTCTCCTGAGATGTGCCGGAAGTGCCGCACAGGGTGTCCCAGAGGGATGGTC AAGGTCGGTGATTGTACACCCTGGAGTGACATCGAATGTGTCCACAAAGAATCAGGTACA AAGCACAGTGGGGAAGCCCCAGCTGTGGAGGAGACGGTGACCTCCAGCCCAGGGACTCCT GCCTCTCCCTGTTCTCTCTCAGGCATCATCATAGGAGTCACAGTTGCAGCCGTAGTCTTG ATTGTGGCTGTGTTTGTTTGCAAGTCTTTACTGTGGAAGAAAGTCCTTCCTTACCTGAAA GGCATCTGCTCAGGTGGTGGTGGGGACCCTGAGCGTGTGGACAGAAGCTCACAACGACCT GGGGCTGAGGACAATGTCCTCAATGAGATCGTGAGTATCTTGCAGCCCACCCAGGTCCCT GAGCAGGAAATGGAAGTCCAGGAGCCAGCAGAGCCAACAGGTGTCAACATGTTGTCCCCC GGGGAGTCAGAGCATCTGCTGGAACCGGCAGAAGCTGAAAGGTCTCAGAGGAGGAGGCTG CTGGTTCCAGCAAATGAAGGTGATCCCACTGAGACTCTGAGACAGTGCTTCGATGACTTT GCAGACTTGGTGCCCTTTGACTCCTGGGAGCCGCTCATGAGGAAGTTGGGCCTCATGGAC AATGAGATAAAGGTGGCTAAAGCTGAGGCAGCGGGCCACAGGGACACCTTGTACACGATG CTGATAAAGTGGGTCAACAAAACCGGGCGAGATGCCTCTGTCCACACCCTGCTGGATGCC TTGGAGACGCTGGGAGAGAGACTTGCCAAGCAGAAGATTGAGGACCACTTGTTGAGCTCT GGAAAGTTCATGTATCTAGAAGGTAATGCAGACTCTGCCATGTCCTAAGTGTGATTCTCT TCAGGAAGTCAGACCTTCCCTGGTTTACCTTTTTTCTGGAAAAAGCCCAACTGGACTCCA GTCAGTAGGAAAGTGCCACAATTGTCACATGACCGGTACTGGAAGAAACTCTCCCATCCA ACATCACCCAGTGGATGGAACATCCTGTAACTTTTCACTGCACTTGGCATTATTTTTATA AGCTGAATGTGATAATAAGGACACTATGGAAATGTCTGGATCATTCCGTTTGTGCGTACT TTGAGATTTGGTTTGGGATGTCATTGTTTTCACAGCACTTTTTTATCCTAATGTAAATGC TTTATTTATTTATTTGGGCTACATTGTAAGATCCATCTACACAGTCGTTGTCCGACTTCA CTTGATACTATATGATATGAACCTTTTTTGGGTGGGGGGTGCGGGGCAGTTCACTCTGTC TCCCAGGCTGGAGTGCAATGGTGCAATCTTGGCTCACTATAGCCTTGACCTCTCAGGCTC AAGCGATTCTCCCACCTCAGCCATCCAAATAGCTGGGACCACAGGTGTGCACCACCACGC CCGGCTAATTTTTTGTATTTTGTCTAGATATAGGGGCTCTCTATGTTGCTCAGGGTGGTC TCGAATTCCTGGACTCAAGCAGTCTGCCCACCTCAGACTCCCAAAGCGGTGGAATTAGAG GCGTGAGCCCCCATGCTTGGCCTTACCTTTCTACTTTTATAATTCTGTATGTTATTATTT TATGAACATGAAGAAACTTTAGTAAATGTACTTGTTTACATAGTTATGTGAATAGATTAG ATAAACATAAAAGGAGGAGACATACAATGGGGGAAGAAGAAGAAGTCCCCTGTAAGATGT CACTGTCTGGGTTCCAGCCCTCCCTCAGATGTACTTTGGCTTCAATGATTGGCAACTTCT ACAGGGGCCAGTCTTTTGAACTGGACAACCTTACAAGTATATGAGTATTATTTATAGGTA GTTGTTTACATATGAGTCGGGACCAAAGAGAACTGGATCCACGTGAAGTCCTGTGTGTGG CTGGTCCCTACCTGGGCAGTCTCATTTGCACCCATAGCCCCCATCTATGGACAGGCTGGG ACAGAGGCAGATGGGTTAGATCACACATAACAATAGGGTCTATGTCATATCCCAAGTGAA CTTGAGCCCTGTTTGGGCTCAGGAGATAGAAGACAAAATCTGTCTCCCACGTCTGCCATG GCATCAAGGGGGAAGAGTAGATGGTGCTTGAGAATGGTGTGAAATGGTTGCCATCTCAGG AGTAGATGGCCCGGCTCACTTCTGGTTATCTGTCACCCTGAGCCCATGAGCTGCCTTTTA GGGTACAGATTGCCTACTTGAGGACCTTGGCCGCTCTGTAAGCATCTGACTCATCTCAGA AATGTCAATTCTTAAACACTGTGGCAACAGGACCTAGAATGGCTGACGCATTAAGGTTTT CTTCTTGTGTCCTGTTCTATTATTGTTTTAAGACCTCAGTAACCATTTCAGCCTCTTTCC AGCAAACCCTTCTCCATAGTATTTCAGTCATGGAAGGATCATTTATGCAGGTAGTCATTC CAGGAGTTTTTGGTCTTTTCTGTCTCAAGGCATTGTGTGTTTTGTTCCGGGACTGGTTTG GGTGGGACAAAGTTAGAATTGCCTGAAGATCACACATTCAGACTGTTGTGTCTGTGGAGT TTTAGGAGTGGGGGGTGACCTTTCTGGTCTTTGCACTTCCATCCTCTCCCACTTCCATCT GGCATCCCACGCGTTGTCCCCTGCACTTCTGGAAGGCACAGGGTGCTGCTGCCTCCTGGT CTTTGCCTTTGCTGGGCCTTCTGTGCAGGACGCTCAGCCTCAGGGCTCAGAAGGTGCCAG TCCGGTCCCAGGTCCCTTGTCCCTTCCACAGAGGCCTTCCTAGAAGATGCATCTAGAGTG TCAGCCTTATCAGTGTTTAAGATTTTTCTTTTATTTTTAATTTTTTTGAGACAGAATCTC ACTCTCTCGCCCAGGCTGGAGTGCAACGGTACGATCTTGGCTCAGTGCAACCTCCGCCTC CTGGGTTCAAGCGATTCTCGTGCCTCAGCCTCCGGAGTAGCTGGGATTGCAGGCACCCGC CACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGTCAG GCTGGTCTCGAACTCCTGACCTCAGGTGATCCACCTTGGCCTCCGAAAGTGCTGGGATTA CAGGCGTGAGCCACCAGCCAGGCCAAGCTATTCTTTTAAAGTAAGCTTCCTGACGACATG AAATAATTGGGGGTTTTGTTGTTTAGTTACATTAGGCTTTGCTATATCCCCAGGCCAAAT AGCATGTGACACAGGACAGCCATAGTATAGTGTGTCACTCGTGGTTGGTGTCCTTTCATG CTTCTGCCCTGTCAAAGGTCCCTATTTGAAATGTGTTATAATACAAACAAGGAAGCACAT TGTGTACAAAATACTTATGTATTTATGAATCCATGACCAAATTAAATATGAAACCTTATA TAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_003842 unedited
CCCCGCCCCGTTGNCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGA GCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGAAT TCGGCACGAGGCATAAATCAGCACGCGGCCGGAGAACCCCGCAATCTCTGCGCCCACAAA ATACACCGACGATGCCCGATCTACTTTAAGGGCTGAAACCCACGGGCCTGAGAGACTATA AGAGCGTTCCCTACCGCCATGGAACAACGGGGACAGAACGCCCCGGCCGCTTCGGGGGCC CGGAAAAGGCACGGCCCAGGACCCAGGGAGGCGCGGGGAGCCAGGCCTGGGCTCCGGGTC CCCAAGACCCTTGTGCTCGTTGTCGCCGCGGTCCTGCTGTTGGTCTCAGCTGAGTCTGCT CTGATCACCCAACAAGACCTAGCTCCCCAGCAGAGAGCGGCCCCACAACAAAAGAGGTCC AGCCCCTCAGAGGGATTGTGTCCACCTGGACACCATATCTCAGAAGACGGTAGAGATTGC ATCTCCTGCAAATATGGACAGGACTATAGCACTCACTGGAATGACCTCCTTTTCTGCTTG CGCTGCACCAGGTGTGATTCAGGTGAAGTGGAGCTAAGTCCCTGCACCACGACCAGAAAC ACAGTGTGTCAGTGCGAAGAAGGCACCTTCCGGGAAGAAAGATCTCCTGAGATGTGCCGG AAGTGCCGCACAGGGTGTCCCAGAGGGATGGTCAGGGGTCGTGATGTACACCCTGGAGTG CATCGAATGTGTCCACAAGAATCAGGTACCGCACAGTGGNGAGCCCCGCTGTGGAGAGAC GGTGACTNCAGCCCAGGACTCTGCCTCTCCTGTTCCTCTCAGCATATCATAGAGTACAGT GCAGCCGANCTGATGTGGCTGGGTTGTTGCAGTCTTATGTGGGAGAAGTCTTCTA >OriGene 3' read for NM_003842 unedited
NGGTCCTGACTNTGNNACCGCGGCCGCATNCTANGATCGAGTTTTTTTTTTTTTTTTTTA TATAAGGTTTCATATTTAATTTGGTCATGGATTCATAAATACATAAGTATTTTGTACACA ATGTGCTTCCTTGTTTGTATTATAACACATTTCAAATAGGGACCTTTGACAGGGCAGAAG CATGAAAGGACACCAACCACGAGTGACACACTATACTATGGCTGTCCTGTGTCACATGCT ATTTGGCCTGGGGATATAGCAAAGCCTAATGTAACTAAACAACAAAACCCCCAATTATTT CATGTCGTCAGGAAGCTTACTTTAAAAGAATAGCTTGGCCTGGCTGGTGGCTCACGCCTG TAATCCCAGCACTTTCGGAGGCCAAGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGC CTGACCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTG GCGGGTGCCTGCAATCCCAGCTACTCCGGAGGCTGAGGCACGAGAATCGCTTGAACCCAG GAGGCGGAGGTTGCACTGAGCCAAGATCGTACCGTTGCACTCCAGCCTGGGCGAGAGAGT GAGATTCTGTCTCAAAAAAATTAAAAATAAAAGAAAAATCTTAAACACTGATAAGGCTGA CACTCTAGATGCATCTTCTAGGAAGGCCTCTGTGGAAGGGACAAGGGACCTGGGACCGGA CTGGCACCTTCTGAGCCCTGAGGCTGAGCGTCCTGCACAGAAGGCCCAGCAAAGGCANAG ACCAGNAGGCAGCAGCACCCTGTGCCTTCCAGAGTGCAGGGGACAACGCGTGGGATGCCA NATGGAANNTGGAGAGGATGGAAGTGCAAAGACCANNAAAGGTCACCCCNCACTTCTAAA ACTNCACAGAACACACAGTCTGAAATGTGTGATCTTCAGC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003842 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003842.3, NP_003833.3 |
| RefSeq Size | 4160 bp |
| RefSeq ORF | 1323 bp |
| Locus ID | 8795 |
| UniProt ID | O14763 |
| Domains | DEATH, TNFR |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Apoptosis, Cytokine-cytokine receptor interaction, Natural killer cell mediated cytotoxicity, p53 signaling pathway |
| Gene Summary | The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201588 | TNFRSF10B (Myc-DDK-tagged)-Human tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 1 |
CNY 3,656.00 |
|
| RC201588L1 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC201588L2 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 1, mGFP tagged |
CNY 6,056.00 |
|
| RC201588L3 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC201588L4 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 1, mGFP tagged |
CNY 6,056.00 |
|
| RG201588 | TNFRSF10B (tGFP-tagged) - Human tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 1 |
CNY 5,256.00 |
|
| SC322224 | TNFRSF10B (untagged)-Human tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 1 |
CNY 3,656.00 |
