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TP53BP2 (NM_005426) Human Untagged Clone
CAT＃: SC111040
TP53BP2 (untagged)-Human tumor protein p53 binding protein, 2 (TP53BP2), transcript variant 2
CNY 7,008.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | 53BP2; ASPP2; BBP; P53BP2; PPP1R13A |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_005426, the custom clone sequence may differ by one or more nucleotides
ATGGATCTGACTCTTGCTGAACTTCAGGAAATGGCATCTCGCCAGCAGCAACAGATTGAAGCCCAGCAAC AATTGCTGGCAACTAAGGAACAGCGCTTAAAGTTTTTGAAACAACAAGATCAGCGACAACAGCAACAAGT TGCTGAGCAGGAGAAACTTAAAAGGCTAAAAGAAATAGCTGAGAATCAGGAAGCTAAGCTAAAAAAAGTG AGAGCACTTAAAGGCCACGTGGAACAGAAGAGACTAAGCAATGGGAAACTTGTGGAGGAAATTGAACAGA TGAATAATTTGTTCCAGCAAAAACAGAGGGAGCTCGTCCTGGCTGTGTCAAAAGTAGAAGAACTGACCAG GCAGCTAGAGATGCTCAAGAACGGCAGGATCGACAGCCACCATGACAATCAGTCTGCAGTGGCTGAGCTT GATCGCCTCTATAAGGAGCTGCAGCTAAGAAACAAATTGAATCAAGAGCAGAATGCCAAGCTACAACAAC AGAGGGAGTGTTTGAATAAGCGTAATTCAGAAGTGGCAGTCATGGATAAGCGTGTTAATGAGCTGAGGGA CCGGCTGTGGAAGAAGAAGGCAGCTCTACAGCAAAAAGAAAATCTACCAGTTTCATCTGATGGAAATCTT CCCCAGCAAGCCGCGTCAGCCCCAAGCCGTGTGGCTGCAGTAGGTCCCTATATCCAGTCGTCTACTATGC CTCGGATGCCCTCAAGGCCTGAATTGCTGGTGAAGCCAGCCCTGCCGGATGGTTCCTTGGTCATTCAGGC TTCAGAGGGGCCGATGAAAATACAGACACTGCCCAACATGAGATCTGGGGCTGCTTCACAAACTAAAGGC TCTAAAATCCATCCAGTTGGCCCTGATTGGAGTCCTTCAAATGCAGATCTTTTCCCAAGCCAAGGCTCTG CTTCTGTACCTCAAAGCACTGGGAATGCTCTGGATCAAGTTGATGATGGAGAGGTTCCGCTGAGGGAGAA AGAGAAGAAAGTGCGTCCGTTCTCAATGTTTGATGCAGTAGACCAGTCCAATGCCCCACCTTCCTTTGGT ACTCTGAGGAAGAACCAGAGCAGTGAAGATATCTTGCGGGATGCTCAGGTTGCAAATAAAAATGTGGCTA AAGTACCACCTCCTGTTCCTACAAAACCAAAACAGATTAATTTGCCTTATTTTGGACAAACTAATCAGCC ACCTTCAGACATTAAGCCAGACGGAAGTTCTCAGCAGTTGTCAACAGTTGTTCCGTCCATGGGAACTAAA CCAAAACCAGCAGGGCAGCAGCCGAGAGTGCTGCTATCTCCCAGCATACCTTCGGTTGGCCAAGACCAGA CCCTTTCTCCAGGTTCTAAGCAAGAAAGTCCACCTGCTGCTGCCGTCCGGCCCTTTACTCCCCAGCCTTC CAAAGACACCTTACTTCCACCCTTCAGAAAACCCCAGACCGTGGCAGCAAGTTCAATATATTCCATGTAT ACGCAACAGCAGGCGCCAGGAAAAAACTTCCAGCAGGCTGTGCAGAGCGCGTTGACCAAGACTCATACCA GAGGGCCACACTTTTCAAGTGTATATGGTAAGCCTGTAATTGCTGCTGCCCAGAATCAACAGCAGCACCC AGAGAACATTTATTCCAATAGCCAGGGCAAGCCTGGCAGTCCAGAACCTGAAACAGAGCCTGTTTCTTCA GTTCAGGAGAACCATGAAAACGAAAGAATTCCTCGGCCACTCAGCCCAACTAAATTACTGCCTTTCTTAT CTAATCCTTACCGAAACCAGAGTGATGCTGACCTAGAAGCCTTACGAAAGAAACTGTCTAACGCACCAAG GCCTCTAAAGAAACGTAGTTCTATTACAGAGCCAGAGGGTCCTAATGGGCCAAATATTCAGAAGCTTTTA TATCAGAGGACCACCATAGCGGCCATGGAGACCATCTCTGTCCCATCATACCCATCCAAGTCAGCTTCTG TGACTGCCAGCTCAGAAAGCCCAGTAGAAATCCAGAATCCATATTTACATGTGGAGCCCGAAAAGGAGGT GGTCTCTCTGGTTCCTGAATCATTGTCCCCAGAGGATGTGGGGAATGCCAGTACAGAGAACAGTGACATG CCAGCTCCTTCTCCAGGCCTTGATTATGAGCCTGAGGGAGTCCCAGACAACAGCCCAAATCTCCAGAATA ACCCAGAAGAACCAAATCCAGAGGCTCCACATGTGCTTGATGTGTACCTGGAGGAGTACCCTCCATACCC ACCCCCACCATACCCATCTGGGGAGCCTGAAGGGCCCGGAGAAGACTCGGTGAGCATGCGCCCGCCTGAA ATCACCGGGCAGGTCTCTCTGCCTCCTGGTAAAAGGACAAACTTGCGTAAAACTGGCTCAGAGCGTATCG CTCATGGAATGAGGGTGAAATTCAACCCCCTTGCTTTACTGCTAGATTCGTCTTTGGAGGGAGAATTTGA CCTTGTACAGAGAATTATTTATGAGGTTGATGACCCAAGCCTCCCCAATGATGAAGGCATCACGGCTCTT CACAATGCTGTGTGTGCAGGCCACACAGAAATCGTTAAGTTCCTGGTACAGTTTGGTGTAAATGTAAATG CTGCTGATAGTGATGGATGGACTCCATTACATTGTGCTGCCTCATGTAACAACGTCCAAGTGTGTAAGTT TTTGGTGGAGTCAGGAGCCGCTGTGTTTGCCATGACCTACAGTGACATGCAGACTGCTGCAGATAAGTGC GAGGAAATGGAGGAAGGCTACACTCAGTGCTCCCAATTTCTTTATGGAGTTCAGGAGAAGATGGGCATAA TGAATAAAGGAGTCATTTATGCGCTTTGGGATTATGAACCTCAGAATGATGATGAGCTGCCCATGAAAGA AGGAGACTGCATGACAATCATCCACAGGGAAGACGAAGATGAAATCGAATGGTGGTGGGCGCGCCTTAAT GATAAGGAGGGATATGTTCCACGTAACTTGCTGGGACTGTACCCAAGAATTAAACCAAGACAAAGGAGCT TGGCCTGA >OriGene 5' read for NM_005426 unedited
TAGAGTTTCATCATGTTGGCCAGGATGGTCTCGATCTCCTGACCTTGTGATCCGCCTGCC TCGGCCTCCCAAAGTGCTGGATTACAGGTGTGAGCCACCACGATCAGCCTCTAGTGTTTA AAAAAGAACGTCCAGTTGCGGATAATGAGCGAATGTTTGATGTTCTTCAACGATTTGGAA GTCAGAGGAACGAAGTTCGCTTCTTCCTTCGTCATGAACGCCCCCCTGGCAGGGACATTG TGAGTGGACCAAGATCTCAGGATCCAAGTTTAAAAAGAAATGGTGTAAAAGTTCCTGGTG AATATCGAAGAAAGGAGAACGGTGTTAATAGTCCTAGGATGGATCTGACTCTTGCTGAAC TTCAGGAAATGGCATCTCGCCAGCAGCAACAGATTGAAGCCCAGCAACAATTGCTGGCAA CTAAGGAACAGCGCTTAAAGTTTTTGAAACAACAAGATCAGCGACAACAGCAACAAGTTG CTGAGCAGGAGAAACTTAAAAGGCTAAAAGAAATAGCTGAGAATCAGGAAGCTAAGCTAA AAAAAGTGAGAGCACTTNAAGGCCACGTGGAACAGAAGAGACTAAGCATGGGGAAACTTG CANAACAGAGGGAGCTCGTCCTGGCTGTGTCAAAGTNAAGAACTGACCANGCAGCTAGGA TGCTCAGAACGGCNGGATCGACAGCACATGACATCANNCTGCAGGGCTGAGCTTGATCGC TCTTTAAGAGCTGCGCTAAGAACAAATGATCAGACAGATGCCAGCTCACAAAAGGGAGGG TTGATAAACGATTTAAAAGGGCGCTGGTTAACTTTATTACTTAGGACCGGTGGGAAAAAG GACCTTCCCAAAAAATATCATTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005426 |
| Insert Size | 4700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_005426.1, NP_005417.1 |
| RefSeq Size | 4802 bp |
| RefSeq ORF | 3018 bp |
| Locus ID | 7159 |
| UniProt ID | Q13625 |
| Domains | SH3, ANK |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) contains an alternate exon and uses a downstream start codon, compared to variant 1. Isoform 2, also known as 53BP2S or short, has a shorter N-terminus, compared to isoform 1. CCDS Note: This CCDS ID represents the short isoform encoded by this gene. It is also known as 53BP2S, and is described in PMIDs 8668206 and 14766226. This isoform is shorter at the N-terminus compared to the full-length isoform, also known as 53BP2L and represented by CCDS44319.1. The presence of an upstream in-frame start codon, use of which would extend the short isoform N-terminus by 62 aa, should be noted. This has a weak Kozak signal compared to a strong Kozak signal for the represented downstream start codon; the use of the downstream start codon is also supported by in vitro translation experiments in PMID:8668206. |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208939 | TP53BP2 (Myc-DDK-tagged)-Human tumor protein p53 binding protein, 2 (TP53BP2), transcript variant 2 |
CNY 11,310.00 |
|
| RC208939L3 | Lenti-ORF clone of TP53BP2 (Myc-DDK-tagged)-Human tumor protein p53 binding protein, 2 (TP53BP2), transcript variant 2 |
CNY 13,210.00 |
|
| RC208939L4 | Lenti-ORF clone of TP53BP2 (mGFP-tagged)-Human tumor protein p53 binding protein, 2 (TP53BP2), transcript variant 2 |
CNY 13,210.00 |
|
| RG208939 | TP53BP2 (tGFP-tagged) - Human tumor protein p53 binding protein, 2 (TP53BP2), transcript variant 2 |
CNY 12,450.00 |
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