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MUS81 (NM_025128) Human Untagged Clone
CAT＃: SC110891
MUS81 (untagged)-Human MUS81 endonuclease homolog (S. cerevisiae) (MUS81)
CNY 4,112.00
Product images
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | SLX3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC110891 sequence for NM_025128 edited (data generated by NextGen Sequencing)
ATGGCGGCCCCGGTCCGCCTGGGCCGGAAGCGCCCGCTGCCTGCCTGTCCCAACCCGCTC TTCGTTCGCTGGCTGACCGAGTGGCGGGACGAGGCGACCCGCAGCAGGCACCGCACGCGC TTCGTATTTCAGAAGGCGCTGCGTTCCCTCCGACGGTACCCACTGCCGCTGCGCAGCGGG AAGGAAGCTAAGATCCTACAGCACTTCGGAGACGGGCTCTGCCGGATGCTGGACGAGCGG CTGCAGCGGCACCGAACATCGGGCGGTGACCATGCCCCGGACTCACCATCTGGAGAGAAC AGTCCAGCCCCGCAGGGGCGACTTGCGGAAGTCCAGGACTCTTCCATGCCAGTTCCTGCC CAGCCCAAAGCGGGAGGCTCTGGCAGCTACTGGCCAGCTCGGCACTCAGGAGCCCGAGTG ATACTGCTGGTGCTCTACCGGGAGCACCTGAATCCTAATGGTCACCACTTCTTAACCAAG GAGGAGCTGCTGCAGAGGTGTGCTCAGAAGTCCCCCAGGGTAGCCCCTGGGAGTGCCCCA CCCTGGCCAGCCCTCCGCTCCCTCCTTCACAGGAACCTGGTCCTCAGGACACACCAGCCA GCCAGGTACTCATTGACCCCAGAGGGCCTGGAGCTGGCCCAGAAGTTGGCCGAGTCAGAA GGCCTGAGCTTGCTGAATGTGGGCATCGGGCCCAAGGAGCCCCCTGGGGAGGAGACAGCA GTGCCAGGAGCAGCTTCAGCAGAGCTTGCCAGTGAAGCAGGGGTCCAGCAGCAGCCACTG GAGCTGAGGCCTGGAGAGTACAGGGTGCTGTTGTGTGTGGACATTGGCGAGACCCGGGGG GGCGGGCACAGGCCGGAGCTGCTCCGAGAGCTACAGCGGCTGCACGTGACCCACACGGTG CGCAAGCTGCACGTTGGAGATTTTGTGTGGGTGGCTCAGGAGACCAATCCTAGAGACCCA GCAAACCCTGGGGAGTTGGTACTGGATCACATTGTGGAGCGCAAGCGACTGGATGACCTT TGCAGCAGCATCATCGACGGCCGCTTCCGGGAGCAGAAGTTCCGACTGAAGCGCTGTGGT CTGGAGCGCCGGGTATACCTGGTGGAAGAGCATGGTTCCGTCCACAACCTCAGCCTTCCT GAGAGCACACTGCTGCAGGCTGTCACCAACACTCAGGTCATTGATGGCTTTTTTGTGAAG CGCACAGCAGACATTAAGGAGTCAGCCGCCTACCTGGCCCTCTTGACTCGGGGCCTGCAG AGACTCTACCAGGGCCACACCCTACGCAGCCGCCCCTGGGGAACCCCTGGGAACCCTGAA TCAGGGGCCATGACCTCTCCAAACCCTCTCTGCTCACTCCTCACCTTCAGTGACTTCAAC GCAGGAGCCATCAAGAATAAGGCCCAGTCGGTGCGAGAAGTGTTTGCCCGGCAGCTGATG CAGGTGCGCGGAGTGAGTGGGGAGAAGGCAGCAGCCCTGGTGGATCGATACAGCACCCCT GCCAGCCTCCTGGCCGCCTATGATGCCTGTGCCACCCCCAAGGAACAAGAGACACTGCTG AGCACCATTAAGTGTGGGCGTCTACAGAGGAATCTGGGGCCTGCTCTGAGCAGGACCTTA TCCCAGCTCTACTGCAGCTACGGCCCCTTGACCTGA Clone variation with respect to NM_025128.4 110 g=>a;537 t=>c;539 g=>c;936 c=>t;1065 g=>a;1248 g=>t >OriGene 5' read for NM_025128 unedited
GTATACGACTCACTATAGGGGCGGCCGCGATTCGGCACGAGGGTGGGAGGGCGGCCGCAG GCTCTCCTCTCGTTAGTGCCCCCTGTGTTTGGGGCCCCGTGATCTCAACGGTCCTGCCCT CGGTCTCCCTCTTCCCCCGCCCCGCCCTGGGCCAGGTGTTCGAATCCCGACTCCAGAACT GGCGGCGTCCCAGTCCCGCGGGCGTGGAGCGCCGGAGGACCCGCCCTCGGGCTCATGGCG GCCCCGGTCCGCCTGGGCCGGAAGCGCCCGCTGCCTGCCTGTCCCAACCCGCTCTTCGTT CGCTGGCTGACCGAGTGGCGGGACGAGGCGACCCGCAGCAGGCACCGCACGCGCTTCGTA TTTCAGAAGGCGCTGCGTTCCCTCCGACGGTACCCACTGCCGCTGCGCAGCGGGAAGGAA GCTAAGATCCTACAGCACTTCGGAGACGGGCTCTGCCGGATGCTGGACGAGCGGCTGCAG CGGCACCGAACATCGGGCGGTGACCATGCCCCGGACTCACCATCTGGAGAGAACAGTCCA GCCCCGCAGGGGCGACTTGCGGAAGTCCAGGACTCTTCCATGCCAGTTCCTGCCCAGCCC AAAGCGGGAGGCTCTGGCAGCTACTGGCCAGCTCGGCACTCAGGAGCCCGAGTGATACTG CTGGTGCTCTANCCGGGAGCACCTGATCCTAATGGTCACCACTTCTTACCCAAGGAGGAG CTGCTGCAGAGGTGTGCTCANAAAGTCCCCCAGGTAGCCCCTGGGAGTGCCCCACCCTGG NCAGGCCTTCGNTCCCTTCTTNACAGGAACCCTGTTNCTCAGACACACAGCCAGCCAGTA CTCATTGACCCCAGAGGCCTGNAGCTTGCCCANAAGTTGCCGAGTCAAAGGCCTGAGCTG CTGATGTGGGCATCGGGCCCAGGAGCCCCTGGGGAG >OriGene 3' read for NM_025128 unedited
ATGGCCGCGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTCTAATGGCCCCCCAAAAAATGTTGTTAAAAGGCTGC CTACCCTGGGTTGGGGAACAAACGGGGGCTGGGGGCTTTTTCACGGCATAACCTCAGGCC AAGGGGCCGAACCTGCAAAAAACCTGGAATAAGGCCCTGCTCAAAGCAGGCCCCAAATTC CTTTGTAAACCCCCACCCTTAAGGGGGCTCACCAGGGCTTTTTGTTCCTTGGGGGGGGCA CAGGCATTATAGGCGGCCAAAAGGCTGGCAGGGGTGCTTTATCAATCCACCAGGGCTGTT GCTTTTTCCCCACTCACTCCGGGCACCTGAATAAGTTGCCGGGCAAACACTTTTCGCACC GACTGGGCCTTATTCTTGAGGGCTCCTGCGTTAAAGTCACTGAAGGGGAGGAGTGACCAA AAAGGGTTTGGAAAGGTCATGGCCCCTGATTCAGGGTTCCCAGGGGTTCCCCAGGGGCGG CTGCGTAGGGTGTGGCCCTGGTAAAGTCTCTGCAGGCCCCGATTCAAAAGGGCCAGGTAG GCGGCTGACTCCTTAATGGCTGCTGCGCGCTTAACAAAAAACCCATCAATGACCTTGAGT GTTTGGAGAACACCCTGCAACCAGTGGCCCCTTCAAAGAAGGCCTGAGGTTTTGTGAACG AGAACCATGTCTCTTCCACCAGTGTTAACCCGGCGGCTCCAAACCACAAGGCTTAAATCG GAAATTTTTGCTCCCGAAACCGCCCGCCAATAAGCTTGTTAAAAGCCATCCAACCGTCGC CCCCCCCAAGTGAACCACCCCACCTCCCCAGGGTTGGCGGCCCCTAGGATGGTCCTCGAC CCCCCCCCAATTTCCACGGGCACTGCCCCCGGGGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_025128 |
| Insert Size | 2280 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_025128.3, NP_079404.2 |
| RefSeq Size | 2343 bp |
| RefSeq ORF | 1656 bp |
| Locus ID | 80198 |
| UniProt ID | Q96NY9 |
| Domains | ERCC4 |
| Protein Pathways | Homologous recombination |
| Gene Summary | This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after inter-strand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks. [provided by RefSeq, Jun 2017] Transcript Variant: This variant (2) uses an alternate in-frame splice site in the coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203373 | MUS81 (Myc-DDK-tagged)-Human MUS81 endonuclease homolog (S. cerevisiae) (MUS81) |
CNY 4,104.00 |
|
| RC203373L1 | Lenti ORF clone of Human MUS81 endonuclease homolog (S. cerevisiae) (MUS81), Myc-DDK-tagged |
CNY 6,504.00 |
|
| RC203373L2 | Lenti ORF clone of Human MUS81 endonuclease homolog (S. cerevisiae) (MUS81), mGFP tagged |
CNY 6,460.00 |
|
| RC203373L3 | Lenti ORF clone of Human MUS81 endonuclease homolog (S. cerevisiae) (MUS81), Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC203373L4 | Lenti ORF clone of Human MUS81 endonuclease homolog (S. cerevisiae) (MUS81), mGFP tagged |
CNY 6,460.00 |
|
| RG203373 | MUS81 (tGFP-tagged) - Human MUS81 endonuclease homolog (S. cerevisiae) (MUS81) |
CNY 5,704.00 |
