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BMP4 (NM_130851) Human Untagged Clone
CAT＃: SC110838
BMP4 (untagged)-Human bone morphogenetic protein 4 (BMP4), transcript variant 3
CNY 3,656.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BMP2B; BMP2B1; MCOPS6; OFC11; ZYME |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_130851 edited
GAATTCGGCACGAGGACGCACTGCTGCAGCTTCCCTGAGCCTTTCCAGCAAGTTTGTTCA AGATTGGCTGTCAAGAATCATGGACTGTTATTATATGCCTTGTTTTCTGTCAAGACACCA TGATTCCTGGTAACCGAATGCTGATGGTCGTTTTATTATGCCAAGTCCTGCTAGGAGGCG CGAGCCATGCTAGTTTGATACCTGAGACGGGGAAGAAAAAAGTCGCCGAGATTCAGGGCC ACGCGGGAGGACGCCGCTCAGGGCAGAGCCATGAGCTCCTGCGGGACTTCGAGGCGACAC TTCTGCAGATGTTTGGGCTGCGCCGCCGCCCGCAGCCTAGCAAGAGTGCCGTCATTCCGG ACTACATGCGGGATCTTTACCGGCTTCAGTCTGGGGAGGAGGAGGAAGAGCAGATCCACA GCACTGGTCTTGAGTATCCTGAGCGCCCGGCCAGCCGGGCCAACACCGTGAGGAGCTTCC ACCACGAAGAACATCTGGAGAACATCCCAGGGACCAGTGAAAACTCTGCTTTTCGTTTCC TCTTTAACCTCAGCAGCATCCCTGAGAACGAGGTGATCTCCTCTGCAGAGCTTCGGCTCT TCCGGGAGCAGGTGGACCAGGGCCCTGATTGGGAAAGGGGCTTCCACCGTATAAACATTT ATGAGGTTATGAAGCCCCCAGCAGAAGTGGTGCCTGGGCACCTCATCACACGACTACTGG ACACGAGACTGGTCCACCACAATGTGACACGGTGGGAAACTTTTGATGTGAGCCCTGCGG TCCTTCGCTGGACCCGGGAGAAGCAGCCAAACTATGGGCTAGCCATTGAGGTGACTCACC TCCATCAGACTCGGACCCACCAGGGCCAGCATGTCAGGATTAGCCGATCGTTACCTCAAG GGAGTGGGAATTGGGCCCAGCTCCGGCCCCTCCTGGTCACCTTTGGCCATGATGGCCGGG GCCATGCCTTGACCCGACGCCGGAGGGCCAAGCGTAGCCCTAAGCATCACTCACAGCGGG CCAGGAAGAAGAATAAGAACTGCCGGCGCCACTCGCTCTATGTGGACTTCAGCGATGTGG GCTGGAATGACTGGATTGTGGCCCCACCAGGCTACCAGGCCTTCTACTGCCATGGGGACT GCCCCTTTCCACTGGCTGACCACCTCAACTCAACCAACCATGCCATTGTGCAGACCCTGG TCAATTCTGTCAATTCCAGTATCCCCAAAGCCTGTTGTGTGCCCACTGAACTGAGTGCCA TCTCCATGCTGTACCTGGATGAGTATGATAAGGTGGTACTGAAAAATTATCAGGAGATGG TAGTAGAGGGATGTGGGTGCCGCTGAGATCAGGCAGTCCTTGAGGATAGACAGATATACA CACCACACACACACACCACATACACCACACACACACGTTCCCATCCACTCACCCACACAC TACACAGACTGCTTCCTTATAGCTGGACTTTTATTTAAAAAAAAAAAAAAAAAACTCGAC >OriGene 5' read for NM_130851 unedited
CCATTCCCCCGCCCGTTGCCGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAA GCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCG CGAATTCGGCACGAGGACGCACTGCTGCAGCTTCCCTGAGCCTTTCCAGCACGTTTGTTC AAGATTGGCTGTCAAGAATCATGGACTGTTATTATATGCCTTGTTTTCTGTCAAGACACC ATGATTCCTGGTAACCGAATGCTGATGGTCGTTTTATTATGCCAAGTCCTGCTAGGAGGC GCGAGCCATGCTAGTTTGATACCTGAGACGGGGAAGAAAAAAGTCGCCGAGATTCAGGGC CACGCGGGAGGACGCCGCTCAGGGCAGAGCCATGAGCTCCTGCGGGACTTCGAGGCGACA CTTCTGCAGATGTTTGGGCTGCGCCGCCGCCCGCAGCCTAGCAAGAGTGCCGTCATTCCG GACTACATGCGGGATCTTTACCGGCTTCAGTCTGGGGAGGAGGAGGAAGAGCAGATCCAC AGCACTGGTCTTGAGTATCCTGAGCGCCCGGCCAGCCGGGCCAACACCGTGAGGAGCTTC CACCACGAAGAACATCTGGAGAACATCCCAGGGACCAGTGAAAACTCTGCTTTTCGTTTC CTCTTTAACCTCAGCAGCATCCCTGAGCGCGAGGTGATCTCCTCTGCAGAGCTTCGGCTC TTCCTGGAGCAGGTGGACCAGNGCCCTGACTGNGCAAGGNGCTTCCCCGTATAACATTNA TGAGGNTATGAAGCCCCCAGCAAACGTGGTGCCTGGGCACCTCATCACACGACTACTGGA CACGAGACTGGTTCACCACATGTGACACGCTGGGACACTTTTGATGTGAGCCCTGCNGTC CTTCGCTGNACCTGGGAGAGCAGCCAACTATGGCCTAGC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_130851 |
| Insert Size | 1600 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_130851.1, NP_570912.1 |
| RefSeq Size | 1779 bp |
| RefSeq ORF | 1227 bp |
| Locus ID | 652 |
| UniProt ID | P12644 |
| Domains | TGFb_propeptide, TGF-beta |
| Protein Families | Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, Induced pluripotent stem cells, Secreted Protein, Stem cell relevant signaling - TGFb/BMP signaling pathway |
| Protein Pathways | Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer, TGF-beta signaling pathway |
| Gene Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. [provided by RefSeq, Jul 2016] Transcript Variant: This variant (3) uses the P2 promoter and differs in the 5' UTR compared to variant 1. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Bone morphogenetic protein 4 provides cancer-supportive phenotypes to liver fibroblasts in patients with hepatocellular carcinoma
,Mano, Y;Yoshio, S;Shoji, H;Tomonari, S;Aoki, Y;Aoyanagi, N;Okamoto, T;Matsuura, Y;Osawa, Y;Kimura, K;Yugawa, K;Wang, H;Oda, Y;Yoshizumi, T;Maehara, Y;Kanto, T;,
J. Gastroenterol.
,PubMed ID 30941514
[BMP4]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC220034 | BMP4 (Myc-DDK-tagged)-Human bone morphogenetic protein 4 (BMP4), transcript variant 3 |
CNY 3,656.00 |
|
| RC220034L1 | Lenti ORF clone of Human bone morphogenetic protein 4 (BMP4), transcript variant 3, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC220034L2 | Lenti ORF clone of Human bone morphogenetic protein 4 (BMP4), transcript variant 3, mGFP tagged |
CNY 5,890.00 |
|
| RC220034L3 | Lenti ORF clone of Human bone morphogenetic protein 4 (BMP4), transcript variant 3, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC220034L4 | Lenti ORF clone of Human bone morphogenetic protein 4 (BMP4), transcript variant 3, mGFP tagged |
CNY 5,890.00 |
|
| RG220034 | BMP4 (tGFP-tagged) - Human bone morphogenetic protein 4 (BMP4), transcript variant 3 |
CNY 5,256.00 |
