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ACOX1 (NM_004035) Human Untagged Clone
CAT＃: SC110818
ACOX1 (untagged)-Human acyl-CoA oxidase 1, palmitoyl (ACOX1), transcript variant 1
CNY 7,384.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ACOX; MITCH; PALMCOX; SCOX |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC110818 sequence for NM_004035 edited (data generated by NextGen Sequencing)
ATGAACCCGGACCTGCGCAGGGAGCGGGATTCCGCCAGCTTCAACCCGGAGCTGCTTACA CACATCCTGGACGGCAGCCCCGAGAAAACCCGGCGCCGCCGAGAGATCGAGAACATGATC CTGAACGACCCAGACTTCCAGCATGAGGACTTGAACTTCCTCACTCGCAGCCAGCGTTAT GAGGTGGCTGTCAGGAAAAGTGCCATCATGGTGAAGAAGATGAGGGAGTTTGGCATCGCT GACCCTGATGAAATTATGTGGTTTAAAAATTTTGTGCACCGAGGGCGGCCTGAGCCTCTG GATCTTCACTTGGGCATGTTCCTGCCCACCTTGCTTCACCAGGCAACTGCGGAGCAGCAG GAGCGCTTCTTCATGCCCGCCTGGAACTTGGAGATCATTGGCACTTATGCCCAGACAGAG ATGGGTCATGGAACTCACCTTCGAGGCTTGGAAACCACAGCCACGTATGACCCTGAAACC CAGGAGTTCATTCTCAACAGTCCTACTGTGACCTCCATTAAATGGTGGCCTGGTGGGCTT GGAAAGACTTCAAATCATGCAATAGTTCTTGCCCAGCTCATCACTAAGGGGAAATGCTAT GGATTACATGCCTTTATCGTACCTATTCGTGAAATCGGGACCCATAAGCCTTTGCCAGGA ATTACCGTTGGTGACATCGGCCCCAAATTTGGTTATGATGAGATAGACAATGGCTACCTC AAAATGGACAACCATCGTATTCCCAGAGAAAACATGCTGATGAAGTATGCCCAGGTGAAG CCTGATGGCACATACGTGAAACCGCTGAGTAACAAGCTGACTTACGGGACCATGGTGTTT GTCAGGTCCTTCCTTGTGGGAGAAGCTGCTCGGGCTCTGTCTAAGGCGTGCACCATTGCC ATCCGATACAGCGCTGTGAGGCACCAGTCTGAAATCAAGCCAGGTGAACCAGAACCACAG ATTTTGGATTTTCAAACCCAGCAGTATAAACTCTTTCCACTCCTGGCCACTGCCTATGCC TTCCAGTTTGTGGGCGCATACATGAAGGAGACCTATCACCGGATTAACGAAGGCATTGGT CAAGGGGACCTGAGTGAACTGCCTGAGCTTCATGCCCTCACCGCTGGACTGAAGGCTTTC ACCTCCTGGACTGCAAACACTGGCATTGAAGCATGTCGGATGGCTTGTGGTGGGCATGGC TATTCTCATTGCAGTGGTCTTCCAAATATTTATGTCAATTTCACCCCAAGCTGTACCTTT GAGGGAGAAAACACTGTCATGATGCTCCAGACGGCTAGGTTCCTGATGAAAAGTTATGAT CAGGTGCACTCAGGAAAGTTGGTGTGTGGCATGGTGTCCTATTTGAACGACCTGCCCAGT CAGCGCATCCAGCCACAGCAGGTAGCAGTCTGGCCAACCATGGTGGATATCAACAGCCCC GAAAGCCTAACCGAAGCATATAAACTCCGTGCAGCCAGATTAGTAGAAATTGCTGCAAAA AACCTTCAAAAAGAAGTGATTCACAGAAAAAGCAAGGAGGTAGCTTGGAACCTAACTTCT GTTGACCTTGTTCGAGCAAGTGAGGCACATTGCCACTATGTGGTAGTTAAGCTCTTTTCA GAAAAACTCCTCAAAATTCAAGATAAAGCCATTCAAGCTGTCTTAAGGAGTTTATGTCTG CTGTATTCTCTGTATGGAATCAGTCAGAACGCGGGGGATTTCCTTCAGGGGAGCATCATG ACAGAGCCTCAGATTACACAAGTAAACCAGCGTGTAAAGGAGTTACTCACTCTGATTCGC TCAGATGCTGTTGCTTTGGTTGATGCATTTGATTTTCAGGATGTGACACTTGGCTCTGTG CTTGGCCGCTATGATGGGAATGTGTATGAAAACTTGTTTGAGTGGGCTAAGAACTCCCCA CTGAACAAAGCAGAGGTCCACGAATCTTACAAGCACCTGAAGTCACTGCAGTCCAAGCTC TGA Clone variation with respect to NM_004035.6 >OriGene 5' read for NM_004035 unedited
CAACATTTTGTAATACGAACTCACTATAGGGCGGCCGCGAATCGGCACCGGGTGCTTACT TCGCTGCCAGCTGGTCGTCGCCATGAACCCGGACCTGCGCAGGGAGCGGGATTCCGCCAG CTTCAACCCGGAGCTGCTTACACACATCCTGGACGGCAGCCCCGAGAAAACCCGGCGCCG CCGAGAGATCGAGAACATGATCCTGAACGACCCAGACTTCCAGCATGAGGACTTGAACTT CCTCACTCGCAGCCAGCGTTATGAGGTGGCTGTCAGGAAAAGTGCCATCATGGTGAAGAA GATGAGGGAGTTTGGCATCGCTGACCCTGATGAAATTATGTGGTTTAAAAATTTTGTGCA CCGAGGGCGGCCTGAGCCTCTGGATCTTCACTTGGGCATGTTCCTGCCCACCTTGCTTCA CCAGGCAACTGCGGAGCAGCAGGAGCGCTTCTTCATGCCCGCCTGGAACTTGGAGATCAT TGGCACTTATGCCCAGACAGAGATGGGTCATGGAACTCACCTTCGAGGCTTGGAAACCAC AGCCACGTATGACCCTGAAACCCAGGAGTTCATTCTCAACAGTCCTACTGTGACCTCCAT TAAATGGTGGCCTGGTGGGCTTGGAAAGACTTCAAATCATGCAATAGTTCTTGCCCAGCT CATCACTAAGGGGAAATGCTATGGATTACATGCCTTTATCGTACCTATTCGTGAAATCGG GACCCATAAGCCTTTGCCAGGAATTACCGTTGGTGACATCGGCCCCAAATTTGGTTATGA TGAGATAGACAATGGCTACCTCANAATGGGACACCATCGTATTCCCAGAGAAAACATGCT GATGAAGTATGCCCCAGTGAAGCCTGATGGCACATACGTGAAACCGGCTGAGTAACAGCT GACTTACGGGACCATGGTGGTTGTCANGGTCCTTCTTGTGGGAGAAGCTGCTCNGGCTCT GTCTAAGCGTGCCN >OriGene 3' read for NM_004035 unedited
TTATAATCTTTTTTTTTTTTTTTGACTTTAAGAAAAAATAATTAAGATGTATTTAACCTT TAAGTATAGAATGATTGTATAAATTAGATTTCAACTGAAAGGACAATTAGCGATTCAGAG AAAGCTCCTAGAAATAGACTGAAAACAAAGCCATACATAGAGTAAGAAATAGAACCTATG GAACTTCCATTTTTCTAACTATAGTTTTTTGGTTTTGTTTTTTCCCAGTTGTTAAAAAAA AAACAACTCACAGTTTCAATATTTTCTGAACCAAAAATCAGAACACATGGTTTGTGTCAA AGGGTTTTTCTGTGCTACGTCTGGGAGTGCTGACCTAAGTGACATTTTTTTTTAATGCCA AATACAGTAATCTCCAAGCTTTTAATGGCTTATGCCAAGATGACAGAATATGTGAAATCT GATTGTCCCAGAGTTACACTCTGCACTCCAAAGCTACAACAGTGCCACAGCTGAGAGGTT TCCCTATACTTCCTACTACTGTGACAATTTAGCAATCCTTCAAATGGAAAATTCCTAATT ACACGAGACAATGGTCCTACAGTAGGCCCGTGCGGAATAAGTTCCCTCGTTGGAAAAATG CTAGCATGAATAGTTTGATAAATGCAATCCATCAGCAAAGGAGAGCAAGCAGGCAGAGAC TGTGCCAAGCAGAAACTCATTCGCATCAAGTTTTCCAAATAAGTTCCTCTCCCCCAGTCC CCTTTTCTTCATTCCTGCTTTTAAGCCCAGCCCCCAGGTAAGTCTGGTAGAACACTGAGC AGGAAAGCTTTGGAGGGTTCTACACCACTTTCAAAATACCTTTGGTTTATAAACACTTAT TAGCCCGTGATTAGCAATTAACATGGGAAAATAATCAACTACCCCGAGAGTTGAATTCG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004035 |
| Insert Size | 3250 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004035.4, NP_004026.2 |
| RefSeq Size | 3445 bp |
| RefSeq ORF | 1983 bp |
| Locus ID | 51 |
| UniProt ID | Q15067 |
| Domains | ACOX, Acyl-CoA_dh |
| Protein Families | Druggable Genome |
| Protein Pathways | alpha-Linolenic acid metabolism, Biosynthesis of unsaturated fatty acids, Fatty acid metabolism, Metabolic pathways, PPAR signaling pathway |
| Gene Summary | The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) encodes isoform a, alternately referred to as ACOX1b per PMID: 17603022. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200230 | ACOX1 (Myc-DDK-tagged)-Human acyl-CoA oxidase 1, palmitoyl (ACOX1), transcript variant 1 |
CNY 7,864.00 |
|
| RC200230L1 | Lenti-ORF clone of ACOX1 (Myc-DDK-tagged)-Human acyl-CoA oxidase 1, palmitoyl (ACOX1), transcript variant 1 |
CNY 10,264.00 |
|
| RC200230L2 | Lenti-ORF clone of ACOX1 (mGFP-tagged)-Human acyl-CoA oxidase 1, palmitoyl (ACOX1), transcript variant 1 |
CNY 5,890.00 |
|
| RC200230L3 | Lenti-ORF clone of ACOX1 (Myc-DDK-tagged)-Human acyl-CoA oxidase 1, palmitoyl (ACOX1), transcript variant 1 |
CNY 5,890.00 |
|
| RC200230L4 | Lenti-ORF clone of ACOX1 (mGFP-tagged)-Human acyl-CoA oxidase 1, palmitoyl (ACOX1), transcript variant 1 |
CNY 5,890.00 |
|
| RG200230 | ACOX1 (tGFP-tagged) - Human acyl-CoA oxidase 1, palmitoyl (ACOX1), transcript variant 1 |
CNY 4,370.00 |
