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TMPRSS3 (NM_032401) Human Untagged Clone
CAT＃: SC110610
TMPRSS3 (untagged)-Human transmembrane protease, serine 3 (TMPRSS3), transcript variant B
CNY 2,400.00
CNY 6,270.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DFNB8; DFNB8, DFNB10, ECHOS1, TADG12; DFNB10; ECHOS1; OTTHUMP00000109345; serine protease TADG12; TADG12; transmembrane protease, serine 3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC110610 sequence for NM_032401 edited (data generated by NextGen Sequencing)
ATGTGCTCCGATGACTGGAAGGGTCACTACRCAAATGTTGCCTGTGCCCAACTGGGTTTC CCAAGCTATGTGAGTTCAGATAACCTCAGAGTGAGCTCGCTGGAGGGGCAGTTCCGGGAG GAGTTTGTGTCCATCGATCACCTCTTGCCAGATGACAAGGTGACTGCATTACACCACTCA GTATATGTGAGGGAGGGATGTGCCTCTGGCCACGTGGTTACCTTGCAGTGCACAGCCTGT GGTCATAGAAGGGGCTACAGCTCACGCATCGTGGGTGGAAACATGTCCTTGCTCTCGCAG TGGCCCTGGCAGGCCAGCCTTCAGTTCCAGGGCTACCACCTGTGCGGGGGCTCTGTCATC ACGCCCCTGTGGATCATCACTGCTGCACACTGTGTTTATGACTTGTACCTCCCCAAGTCA TGGACCATCCAGGTGGGTCTAGTTTCCCTGTTGGACAATCCAGCCCCATCCCACTTGGTG GAGAAGATTGTCTACCACAGCAAGTACAAGCCAAAGAGGCTGGGCAATGACATCGCCCTT ATGAAGCTGGCCGGGCCACTCACGTTCAATGAAATGATCCAGCCTGTGTGCCTGCCCAAC TCTGAAGAGAACTTCCCCGATGGAAAAGTGTGCTGGACGTCAGGATGGGGGGCCACAGAG GATGGANNNGGTGACGCCTCCCCTGTCCTGAACCACGCGGCCGTCCCTTTGATTTCCAAC AAGATCTGCAACCACAGGGACGTGTACGGTGGCATCATCTCCCCCTCCATGCTCTGCGCG GGCTACCTGACGGGTGGCGTGGACAGCTGCCAGGGGGACAGCGGGGGGCCCCTGGTGTGT CAAGAGAGGAGGCTGTGGAAGTTAGTGGGAGCGACCAGCTTTGGCATCGGCTGCGCAGAG GTGAACAAGCCTGGGGTGTACACCCGTGTCACCTCCTTCCTGGACTGGATCCACGAGCAG ATGGAGAGAGACCTAAAAACCTGA Clone variation with respect to NM_032401.1 31 g=>r;667 g=>n;668 c=>n;669 a=>n >OriGene 5' read for NM_032401 unedited
NGGTTCANATTATGTATACGACTCCTATAGGCGGCCGGATTGGCCGAGGGAAGGGCTGTG TTTATGGGAAGCCAGTACACTGTGGCCTACTATCTCTTCCGTGGTGCCATCTACATTTTT GGGACTCGGGAATTATGAGGTAGAGGTGGAGGCGGAGCCGGATGTCAGAGGTCCTGAAAT AGTCACCATGGGGGAAAATGATCCGCCTGCTGTTGAAGCCCCCTTCTCATTCCGATCGCT TTTTGGCCTTGATGATTTGAAAATAAGTCCTGTTGCACCAGATGCAGATGCTGTTGCTGC ACAGATCCTGTCACTGCTGCCATTGAAGTTTTTTCCAATCATCGTCATTGGGATCATTGC ATTGATATTAGCACTGGCCATTGGTCTGGGCATCCACTTCGACTGCTCAGGGAAGTACAG ATGTCGCTCATCCTTTAAGTGTATCGAGCTGATAGCTCGATGTGACGGAGTCTCGGATTG CAAAGACGGGGAGGACGAGTACCGCTGTGTCCGGGTGGGTGGTCAGAATGCCGTGCTCCA GGTGTTCACAGCTGCTTCGTGGAAGACCATGTGCTCCGATGACTGGAAGGGTCACTACAC AAATGTTGCCTGTGCCCAACTGGGTTTCCCAAGCTATGTGAGTTCAGATAACCCTCAGAG TGAGCTCGCTGGAGGGGCAGTTCCGGGAGGAGTTTGTGTTCATCGATCACCTCTTGCCAG ATGAACAGGGTGACTGCATTACACCACTCCATATATGTGAGGGAAGGGATGTGCCTCTGG CCCACGTGTTTCACCTGCAGTGCACAGCCTGTGGTCATAACAACGCCTACCGCTCACGCA TCCGGGGTGGAAACATGTTCCTTCTCCTCGCATGGCCCTGGCAGGCCACCCTCTCATTCC AGGCTACCCCCTGGCG >OriGene 3' read for NM_032401 unedited
CTATGGAACGCGGCACGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGAGGGAAGGA AACATATTATTTGGAATCAAGGGCAATAATACGTCAAGCACCAAATGCTACAAAGAAATC ATGAAAATAGGCCTTAAACGAGTCATTCCTAGATTAACCTCCCCACATGTGAAAATAAGT CTTGGAAGTAGAAAGGGTGGGTTTGGTTCTGGTCCCTAGAGATGAAAACGTGCAGTGACT GCAGTTCTGCACTTCTGGGCTGGTGCGTCTTTTCTGAGTGGCTGTTGGTGGCTTTGCACG TGAGGTCACATAACTGCTTATCTCGTCAGGAATTTTGCAAGACCCTGGAGAGAAAACCAG ATGGACCAGTGGGAAAGGCCGCCCTTGCAAGTTGCTGCTTCTTTTGTTCTTAGTGAAGAT CAGAAAGGAGCGTGAGGCTAGGCGTGGTGGCCCATGCCTGTAATCCCAGCACTGTGGGAG GCTGAAGCAGGCACATCATTTGAGGTCAGGGGTTTGAGAGCAGCCTGGCCAACATGGTGA AACCCTGTCTCTACTAAAAATACAAAAATTAGTTGGGTGTGGTGGCGGGCACCTGTGGTC CCAGCTACTGGGGAAGCTGAGGCAAGAGAATCGCTTGAACCAGGGAAGCGGAGGCTGCAG TGAGCAGGNATTTCGCCACTGCACTCCAGCCTGGGCAACAGAGCGAGACTCCACCTCAAA AAACAAAAAACAAAAAGCAGCTTGAAAGCTGTGCTGGAATCAAATGGAAGGGTGCCTCTT TCGGGCCTGCTACTGGTGCCCGGACTCANAGCTCCAAGGTTGTCTGCTCGTGTGCAGGTT CCTCCCCGGAGTCCACGGGAGGAATCGGCTGGCTTCTCACCTCAGAACCAGGTGGCTACT TGCCCCCTCCTCTTCAGGTTTTAGGGCTCCTCCTCTGCCGCGGTCCAGCCAGAAGGAGGG ACCGGTTTCACCCAGCCTGGTACCTTGGCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_032401 |
| Insert Size | 2290 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_032401.1, NP_115777.1 |
| RefSeq Size | 2554 bp |
| RefSeq ORF | 984 bp |
| Locus ID | 64699 |
| Domains | Tryp_SPc |
| Protein Families | Druggable Genome, Protease, Transmembrane |
| Gene Summary | This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012] Transcript Variant: This variant (B) lacks exons 1 and 2, but contains 384 nt of intron 2 preceding exon 3, possibly through the use of an alternative splice donor site. As a result, this variant lacks the exon 2 start codon and translation begins at a downstream in-frame start codon. The encoded protein has a 127 aa shorter N-terminus, as compared to isoform 1, and is identical to the protein encoded by variant C. |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224957 | TMPRSS3 (Myc-DDK-tagged)-Human transmembrane protease, serine 3 (TMPRSS3), transcript variant B |
CNY 2,400.00 |
|
| RC224957L3 | Lenti ORF clone of Human transmembrane protease, serine 3 (TMPRSS3), transcript variant B, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC224957L4 | Lenti ORF clone of Human transmembrane protease, serine 3 (TMPRSS3), transcript variant B, mGFP tagged |
CNY 5,890.00 |
|
| RG224957 | TMPRSS3 (tGFP-tagged) - Human transmembrane protease, serine 3 (TMPRSS3), transcript variant B |
CNY 4,370.00 |
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