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KCNK10 (NM_021161) Human Untagged Clone
CAT＃: SC110477
KCNK10 (untagged)-Human potassium channel, subfamily K, member 10 (KCNK10), transcript variant 1
CNY 4,016.00
CNY 8,650.00
| Cited in 3 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | K2p10.1; PPP1R97; TREK-2; TREK2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_021161, the custom clone sequence may differ by one or more nucleotides
ATGTTTTTTCTCTACACAGACTTCTTTCTTTCCTTGGTGGCCGTTCCCGCAGCAGCACCGGTGTGCCAGC CCAAGAGCGCCACTAACGGGCAACCCCCGGCTCCGGCTCCGACTCCAACTCCGCGCCTGTCCATTTCCTC CCGAGCCACAGTGGTAGCCAGGATGGAAGGCACCTCCCAAGGGGGCTTGCAGACCGTCATGAAGTGGAAG ACGGTGGTTGCCATCTTTGTGGTTGTGGTGGTCTACCTTGTCACTGGCGGTCTTGTCTTCCGGGCATTGG AGCAGCCCTTTGAGAGCAGCCAGAAGAATACCATCGCCTTGGAGAAGGCGGAATTCCTGCGGGATCATGT CTGTGTGAGCCCCCAGGAGCTGGAGACGTTGATCCAGCATGCTCTTGATGCTGACAATGCGGGAGTCAGT CCAATAGGAAACTCTTCCAACAACAGCAGCCACTGGGACCTCGGCAGTGCCTTTTTCTTTGCTGGAACTG TCATTACGACCATAGGGTATGGGAATATTGCTCCGAGCACTGAAGGAGGCAAAATCTTTTGTATTTTATA TGCCATCTTTGGAATTCCACTCTTTGGTTTCTTATTGGCTGGAATTGGAGACCAACTTGGAACCATCTTT GGGAAAAGCATTGCAAGAGTGGAGAAGGTCTTTCGAAAAAAGCAAGTGAGTCAGACCAAGATCCGGGTCA TCTCAACCATCCTGTTCATCTTGGCCGGCTGCATTGTGTTTGTGACGATCCCTGCTGTCATCTTTAAGTA CATCGAGGGCTGGACGGCCTTGGAGTCCATTTACTTTGTGGTGGTCACTCTGACCACGGTGGGCTTTGGT GATTTTGTGGCAGGGGGAAACGCTGGCATCAATTATCGGGAGTGGTATAAGCCCCTAGTGTGGTTTTGGA TCCTTGTTGGCCTTGCCTACTTTGCAGCTGTCCTCAGTATGATCGGAGATTGGCTACGGGTTCTGTCCAA AAAGACAAAAGAAGAGGTGGGTGAAATCAAGGCCCATGCGGCAGAGTGGAAGGCCAATGTCACGGCTGAG TTCCGGGAGACACGGCGAAGGCTCAGCGTGGAGATCCACGATAAGCTGCAGCGGGCGGCCACCATCCGCA GCATGGAGCGCCGGCGGCTGGGCCTGGACCAGCGGGCCCACTCACTGGACATGCTGTCCCCCGAGAAGCG CTCTGTCTTTGCTGCCCTGGACACCGGCCGCTTCAAGGCCTCATCCCAGGAGAGCATCAACAACCGGCCC AACAACCTGCGCCTGAAGGGGCCGGAGCAGCTGAACAAGCATGGGCAGGGTGCGTCCGAGGACAACATCA TCAACAAGTTCGGGTCCACCTCCAGACTCACCAAGAGGAAAAACAAGGACCTCAAAAAGACCTTGCCCGA GGACGTTCAGAAAATCTACAAGACCTTCCGGAATTACTCCCTGGACGAGGAGAAGAAAGAGGAGGAGACG GAAAAGATGTGTAACTCAGACAACTCCAGCACAGCCATGCTGACGGACTGTATCCAGCAGCACGCTGAGT TGGAGAACGGAATGATACCCACGGACACCAAAGACCGGGAGCCGGAGAACAACTCATTACTTGAAGACAG AAACTAA >OriGene 5' read for NM_021161 unedited
NGGTTCACATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCAGCCTTC CCATGCCGGGCCACACGGCATTCATTAAAGTGGTGGGGCAACTATTGCTGCGCTCCGGCC GGGCAGGTTTTGAGCTGCAGAGACCCGTGCCCGGTAGCAGCGCTTTGCCACCGAGTGCAC CCAGGACGCAGTGGCCGCCAGCCCGGGTCTCCTGCTGGGGGCCGGCGAGTGAAGGGAGAC TTTGCGCCACGATGTTTTGTTTTCCTGCCGCAGGAACGCTAGGCAGTCTCTTTCCACCGG ACTTAACCCGCCTGAAGCAATAGCCATGGAAGTTGCGGCGGCACAGAGGGAGACAGAACC GCTTGGCGCGGCATCTTTCTTGGATGTTTTTTCTCTACACAGACTTCTTTCTTTCCTTGG TGGCCGTTCCCGCAGCAGCACCGGTGTGCCAGCCCAAGAGCGCCACTAACGGGCAACCCC CGGCTCCGGCTCCGACTCCAACTCCGCGCCTGTCCATTTCCTCCCGAGCCACAGTGGTAG CCAGGATGGAAGGCACCTCCCAAGGGGCTTGCAGACCGTCATGAAGTGGAAGACGGTGGT TGCCATCTTTGTGGTTGNNGGNTGGTCTACCTTGTCACTGGCGGTCTTGTCTTCCGGGCA TTGGAGCAGCCCTTTGAGAGCAGCCAGAAGAATACCATCGCCTTGGAGAAGGCGGNATTC CTGCCGGGATCATGTCTGTGTGAGCCCCCANGAGCTGGAGAACGTGATCCAGCATGCTCT TGATGCTGACAATGCGGGAGTCAGTCCAATAGGAAATCTTCCAACACAGCAGCCACTGGG ACCTCGGCAGTGCCTTTTTCTTTGCTGGAACTGTCATTACGACCATAGGTATTGGGATTA TTGCTCCA >OriGene 3' read for NM_021161 unedited
AGCTATGGCCGCGGCCGCATTCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTT GAGATCCATGGACAGTTTAATTAGGAAGCTTCGACTTGTTAGAATAACAGAGGAAGTCCC AGTTATCTACCTATTCCTTAAAACACATTTTGTCAGGCTGGAATGATTCCCATAGTAAAA CTCAACATCCACACCTGCATAAACATCGCCTCCCAAGTGACTATTTATTACTGAGTCGAC ACAGGATGTCACCAGTGAGCCTCATCTCCAGTCCAATGGAGGAGTTGACTTAAACCTTCC TTGGACAGGAAGGGTCTCATAAGCAATGCCAGAACTTCAACAGAGCCTAAAGGTCTGGGG ACAGGGAGATGGGACTTCATGTGCTCCAGGCAGGGAAGAGCTGTGCATTTTTGAGAAATG GGCAGGGACAGGTCTTCCATGGTACCAGTGGTTGAGGATGTCGTGGGTACAACTTTCCCT GGAGGTCAGAAAGCATGAGACAGTTTCTGGAAGTCTCCGCTAGTGCTGTGATCTTTTGGT AAATCCACACTGCGGGTTAGTTACGTAAAATCCCGTGAACTCTGNTAAAGGTAGCAGTGA GCCTAGAACACCCATAACCAGCAACTGCCTGGTGTTGCCAGGTCCAAATGCTTTCACGTG TGGCCCAAAGAGCTAGCTGTGAACCAGCCATTATGATAAAGACTGAGGCCTACCCAGGAG TATGTATTTTCCCCTTCTGATACAACCCATTTAAATCATCATGCACCTATGACTAGCCAT TCCCGACTTTCTCTGCGGGATGTCTAGCCTTCCGACCATCATAATATGGAGGGTAACTTA ACGTTGCCTGAAACATCAGTCTAGGTGGTCCAGTTTATGGGAACCCGTGGGAGAGTGNAA CCACCCAGGGCCGGGGGACTTTTTAAAAAAGGATGCCCAACTAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_021161 |
| Insert Size | 4200 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_021161.3, NP_066984.1 |
| RefSeq Size | 2710 bp |
| RefSeq ORF | 1617 bp |
| Locus ID | 54207 |
| UniProt ID | P57789 |
| Protein Families | Druggable Genome, Ion Channels: Potassium, Transmembrane |
| Gene Summary | The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2008] Transcript Variant: This variant (1, also known as TREK2 splice variant a) encodes the shortest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Triple arginine residues in the proximal C-terminus of TREK K+channels are critical for the biphasic regulation by PIP2
,Woo, J;Jeon, YK;Zhang, YH;Nam, JH;Shin, DH;Kim, SJ;,
Am. J. Physiol., Cell Physiol.
,PubMed ID 30576235
[KCNK10]
|
|
PD-L1 inhibits acute and chronic pain by suppressing nociceptive neuron activity via PD-1
,Chen, G;Kim, YH;Li, H;Luo, H;Liu, DL;Zhang, ZJ;Lay, M;Chang, W;Zhang, YQ;Ji, RR;,
Nat. Neurosci.
,PubMed ID 28530662
[KCNK10]
|
|
Activation of neurotensin receptor 1 facilitates neuronal excitability and spatial learning and memory in the entorhinal cortex: beneficial actions in an Alzheimer's disease model
,Xiao, Z;Cilz, NI;Kurada, L;Hu, B;Yang, C;Wada, E;Combs, CK;Porter, JE;Lesage, F;Lei, S;,
J. Neurosci.
,PubMed ID 24828655
[KCNK10]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222775 | KCNK10 (Myc-DDK-tagged)-Human potassium channel, subfamily K, member 10 (KCNK10), transcript variant 1 |
CNY 4,008.00 |
|
| RC222775L3 | Lenti ORF clone of Human potassium channel, subfamily K, member 10 (KCNK10), transcript variant 1, Myc-DDK-tagged |
CNY 6,650.00 |
|
| RC222775L4 | Lenti ORF clone of Human potassium channel, subfamily K, member 10 (KCNK10), transcript variant 1, mGFP tagged |
CNY 6,650.00 |
|
| RG222775 | KCNK10 (tGFP-tagged) - Human potassium channel, subfamily K, member 10 (KCNK10), transcript variant 1 |
CNY 5,608.00 |
