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SIVA (SIVA1) (NM_006427) Human Untagged Clone
CAT＃: SC110170
SIVA1 (untagged)-Human SIVA1, apoptosis-inducing factor (SIVA1), transcript variant 1
CNY 2,400.00
CNY 3,990.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD27BP; SIVA; Siva-1; Siva-2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_006427, the custom clone sequence may differ by one or more nucleotides
ATGCCCAAGCGGAGCTGCCCCTTCGCGGACGTGGCCCCGCTACAGCTCAAGGTCCGCGTGAGCCAGAGGG AGTTGAGCCGCGGCGTGTGCGCCGAGCGCTACTCGCAGGAGGTCTTCGAGAAGACCAAGCGACTCCTGTT CCTCGGGGCCCAGGCCTACCTGGACCACGTGTGGGATGAAGGCTGTGCCGTCGTTCACCTGCCAGAGTCC CCAAAGCCTGGCCCTACAGGGGCCCCGAGGGCTGCACGTGGGCAGATGCTGATTGGACCAGACGGCCGCC TGATCAGGAGCCTTGGGCAGGCCTCCGAAGCTGACCCATCTGGGGTAGCGTCCATTGCCTGTTCCTCATG CGTGCGAGCCGTGGATGGGAAGGCGGTCTGCGGTCAGTGTGAGCGAGCCCTGTGCGGGCAGTGTGTGCGC ACCTGCTGGGGCTGCGGCTCCGTGGCCTGTACCCTGTGTGGCCTCGTGGACTGCAGTGACATGTACGAGA AAGTGCTGTGCACCAGCTGTGCCATGTTCGAGACCTGA >OriGene 5' read for NM_006427 unedited
GCACCAGCATGCCCAAGCGGAGCTGCCCCTTCGCGGACGTGGCCCCGCTACAGCTCAAGG TCCGCGTGAGCCAGAGGGAGTTGAGCCGCGGCGTGTGCGCCGAGCGCTACTCGCAGGAGG TCTTCGAGAAGACCAAGCGACTCCTGTTCCTCGGGGCCCAGGCCTACCTGGACCACGTGT GGGATGAAGGCTGTGCCGTCGTTCACCTGCCAGAGTCCCCAAAGCCTGGCCCTACAGGGG CCCCGAGGGCTGCACGTGGGCAGATGCTGATTGGACCAGACGGCCGCCTGATCAGGAGCC TTGGGCAGGCCTCCGAAGCTGACCCATCTGGGGTAGCGTCCATTGCCTGTTCCTCATGCG TGCGAGCCGTGGATGGGAAGGCGGTCTGCGGTCAGTGTGAGCGAGCCCTGTGCGGGCAGT GTGTGCGCACCTGCTGGGGCTGCGGCTCCGTGGCCTGTACCCTGTGTGGCCTCGTGGACT GCAGTGACATGTACGAGAAAGTGCTGTGCACCAGCTGTGCCATGTTCGAGACCTGAGGCT GGCTCAAGCCGGCTGCCTTCACCGGGAGCCACGCCGTGCATGGCAGCCTTCCCTGGACGA GCGCTCGGTGTTCACACTGAACTGTGGGGTCGACGGGAGGGGTGCCTTTTACATGTTCTA TTTTGTATCCTAATGACAGAATGAATAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_006427 |
| Insert Size | 3200 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006427.2, NP_006418.2 |
| RefSeq Size | 751 bp |
| RefSeq ORF | 528 bp |
| Locus ID | 10572 |
| UniProt ID | O15304 |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes an E3 ubiquitin ligase that regulates cell cycle progression, cell proliferation and apoptosis. The N-terminus of this protein binds to the cytoplasmic tail of the CD27 antigen, a member of the tumor necrosis factor receptor (TNFR) superfamily. In response to UV radiation-induced DNA damage, this protein has been shown to mediate the ubiquitination of proliferating cell nuclear antigen (PCNA), an important step in translesion DNA synthesis. [provided by RefSeq, Sep 2018] Transcript Variant: This variant (1) is the predominant and longer transcript. It encodes isoform 1 and includes the apoptotic properties of Siva. |
Documents
| Product Manuals |
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215680 | SIVA1 (Myc-DDK-tagged)-Human SIVA1, apoptosis-inducing factor (SIVA1), transcript variant 1 |
CNY 2,400.00 |
|
| RC215680L1 | Lenti ORF clone of Human SIVA1, apoptosis-inducing factor (SIVA1), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC215680L2 | Lenti ORF clone of Human SIVA1, apoptosis-inducing factor (SIVA1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC215680L3 | Lenti ORF clone of Human SIVA1, apoptosis-inducing factor (SIVA1), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC215680L4 | Lenti ORF clone of Human SIVA1, apoptosis-inducing factor (SIVA1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG215680 | SIVA1 (tGFP-tagged) - Human SIVA1, apoptosis-inducing factor (SIVA1), transcript variant 1 |
CNY 4,000.00 |
