BAIAP2 (NM_017450) Human Untagged Clone

CAT#: SC110154

BAIAP2 (untagged)-Human BAI1-associated protein 2 (BAIAP2), transcript variant 1



  "NM_017450" in other vectors (6)

CNY 5,832.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (3)
BAIAP2 mouse monoclonal antibody, clone OTI 1D9 (formerly 1D9)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms BAP2; FLAF3; IRSP53; WAML
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC110154 sequence for NM_017450 edited (data generated by NextGen Sequencing)
ATGTCTCTGTCTCGCTCAGAGGAGATGCACCGGCTCACGGAAAATGTCTATAAGACCATC
ATGGAGCAGTTCAACCCTAGCCTCCGGAACTTCATCGCCATGGGGAAGAATTACGAGAAG
GCACTGGCAGGTGTGACGTATGCAGCCAAAGGCTACTTTGACGCCCTGGTGAAGATGGGG
GAGCTGGCCAGCGAGAGCCAGGGCTCCAAAGAACTCGGAGACGTTCTCTTCCAGATGGCT
GAAGTCCACAGGCAGATCCAGAATCAGCTGGAAGAAATGCTGAAGTCTTTTCACAACGAG
CTGCTTACGCAGCTGGAGCAGAAGGTGGAGCTGGACTCCAGGTATCTGAGTGCTGCGCTG
AAGAAATACCAGACTGAGCAAAGGAGCAAAGGCGACGCCCTGGACAAGTGTCAGGCTGAG
CTGAAGAAGCTTCGGAAGAAGAGCCAGGGCAGCAAGAATCCTCAGAAGTACTCGGACAAG
GAGCTGCAGTACATCGACGCCATCAGCAACAAGCAGGGCGAGCTGGAGAATTACGTGTCC
GACGGCTACAAGACCGCACTGACAGAGGAGCGCAGGCGCTTCTGCTTCCTGGTGGAGAAG
CAGTGCGCCGTGGCCAAGAACTCCGCGGCCTACCACTCCAAGGGCAAGGAGCTGCTGGCG
CAGAAGCTGCCGCTGTGGCAACAGGCCTGTGCCGACCCCAGCAAGATCCCGGAGCGCGCG
GTGCAGCTCATGCAGCAGGTGGCCAGCAACGGCGCCACCCTCCCCAGCGCCCTGTCGGCC
TCCAAGTCCAACCTGGTCATTTCCGACCCCATTCCGGGGGCCAAGCCCCTGCCGGTGCCC
CCCGAGCTGGCACCGTTCGTGGGGCGGATGTCTGCCCAGGAGAGCACACCCATCATGAAC
GGCGTCACAGGCCCGGATGGCGAGGACTACAGCCCGTGGGCTGACCGCAAGGCTGCCCAG
CCCAAATCCCTGTCTCCTCCGCAGTCTCAGAGCAAGCTCAGCGACTCCTACTCCAACACA
CTCCCCGTGCGCAAGAGCGTGACCCCAAAAAACAGCTATGCCACCACCGAGAACAAGACT
CTGCCTCGCTCGAGCTCCATGGCAGCCGGCCTGGAGCGCAATGGCCGTATGCGGGTGAAG
GCCATCTTCTCCCACGCTGCTGGGGACAACAGCACCCTCCTGAGCTTCAAGGAGGGTGAC
CTCATTACCCTGCTGGTGCCTGAGGCCCGCGATGGCTGGCACTACGGAGAGAGTGAGAAG
ACCAAGATGCGGGGCTGGTTTCCCTTCTCCTACACCCGGGTCTTGGACAGCGATGGCAGT
GACAGGCTGCACATGAGCCTGCAGCAAGGGAAGAGCAGCAGCACGGGCAACCTCCTGGAC
AAGGACGACCTGGCCATCCCACCCCCCGATTACGGCGCCGCCTCCCGGGCCTTCCCCGCC
CAGACGGCCAGCGGCTTCAAGCAGAGGCCCTACAGTGTGGCCGTGCCCGCCTTCTCCCAG
GGCCTGGATGACTATGGAGCGCGGTCCATGAGCAGTGGCAGCGGCACGCTGGTGTCCACA
GTGTGA

Clone variation with respect to NM_017450.2
>OriGene 5' read for NM_017450 unedited
TGCATATTTGTATACGACTCCTATAGGCGGCNCGCGAATTCGCACGAGGGTCCGCTTTCG
TCTCCGTCCTGCTGCCGTTACCGCCGCTGCTGCCGCCGCTTGCGTCCCCCGCTCCGGTCT
GTGGTGCAGCCGGGACCCAGGACCATGTCTCTGTCTCGCTCAGAGGAGATGCANNCCGGC
TCACGGAAAATGTCTATAAGACCATCATGGAGCAGTTCAACCCTAGCCTCCGGAACTTCA
TCGCCATGGGGAAGAATTACGAGAAGGCACTGGCAGGTGTGACGTATGCAGCCAAAGGCT
ACTTTGACGCCCTGGTGAAGATGGGGGAGCTGGCCAGCGAGAGCCAGGGCTCCAAAGAAC
TCGGAGACGTTCTCTTCCAGATGGCTGAAGTCCACAGGCAGATCCAGAATCAGCTGGAAG
AAATGCTGAAGTCTTTTCACAACGAGCTGCTTACGCAGCTGGAGCAGAAGGTGGAGCTGG
ACTCCAGGTATCTGAGTGCTGCGCTGAAGAAATACCAGACTGAGCAAAGGAGCAAAGGCG
ACGCCCTGGACAAGTGTCAGGCTGAGCTGAAGAAGCTTCGGAAGAAGAGCCAGGGCAGCA
AGAATCCTCAGAAGTACTCGGACAAGGAGCTGCAGTACATCGACGCCATCAGCAACAAGC
AGGGCGAGCTGGAGAATTACGTGTCCGACGGCTACAAGACCGCACTGACAGAGGAGCGCA
NGCGCTTCTGCTTCCTGGTGGAGAAGCAGTGCGCCGTGGCCAAGAACTCCGCGGNCTACC
ACTCCCAGGGCAAGGAGCTGCTGGCGCANAAGCTGCCGCTGTGCACCAGGCCTGTGCCGA
CCCAGCAAGATCCCCGACGCGCCGTGCAGTTCATGCACAAGGTGGCCGCACCGGTGCACC
CTCCCAAGCCCTGTGGCCTCCAGTCACCTG
>OriGene 3' read for NM_017450 unedited
CCGCGGGCCGCAATCTAAAGTCGAGTNNTTNTTTTTTTTTTTTCTTTTTTTTTTTTTTTT
AAGATTTTTCTTTTTCTTCAAACTTTAGACCTGGCTCACGGCGAGCCTTAAAAAACAGTG
AGTGCCACAGACACTGCAGGGTGAGGCCGAGGGTGCCCCGCACGGCCCAGCAGGTCCTGC
CTGGCAGTTTCTGCTCAAAAGGCTGGGACACACAGGATGGGGCGCGTAAACACAGGGGAG
GGGGGGCGGATGGAGCAGCACCATGGACCCTGGGGGATCACAGAGTCTGGGGTCACCAAC
CAAAAGGCATGGGGCAGGTGGAAAAGAAAAACAACCCAAGAACAAACCAGCGAGAGCTGA
GGAGGAAAACGGACGAGACCAGGGGGAAGGCGCGGAAGCTCTTCAGAGCAGCGGCTGCCC
GGNGTCAGCGTCCTCACACTGTGGACACCAGCGTGCCGCTGCCACTGCTCATGGACCGCG
CTCCATAGTCATCCAGGCCCTGGAGAAGGCGGGCACGGCCACACTGTANGGCCTCTGCTT
GAAGCCGCTGGCCGTCTGGGCGGAGAAGGCCCGGNAGGCNGCCGCCGTAATCGGNGGGTG
GGATGGGCCAGTCGTCCTTTGTCAGGAGGNTGCCCGTGCTGCTGCTCTTCCCTTGCCTGC
AGCTCATGTGCAGCCTGTCACTGGCATCGCTGNCCAAGACCCGGGTGTAGGAAAAGGGGA
CCCAACCCCGGATCTTGGCTCTTTCACTCTTCTCGNAAGGGCAGCCATCGGGGGGCCTAA
AGCACCAACAGGGGTATGAGGTCACCCTTCTTGAACCTCAGGAAGGGGCTGTTGCCCCAC
CACGCGGGAAAAAAAGGCGCTCAACCCGATACCGCCATTGGCCTCCAGGCCCGGTGCCAT
GGATTTGAGCGAGGCAGAGTCTTGTTTGGGGGGGGCAAATTTGGTTTTGGGGGACCCCTT
TCGCCCGGGGAGGTGTTGAAATAGAATCTTAAACTCCTCTTGACATGGGAGAAACAGGAT
TGGGCTTGCACT
Restriction Sites NotI-NotI     
ACCN NM_017450
Insert Size 2260 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_017450.1, NP_059344.1
RefSeq Size 3168 bp
RefSeq ORF 1566 bp
Locus ID 10458
UniProt ID Q9UQB8
Domains SH3
Protein Families Druggable Genome
Protein Pathways Adherens junction, Regulation of actin cytoskeleton
Gene Summary The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]
Transcript Variant: This variant (1) shares identical sequence with variants 2, 3 and 4, but diverges after amino acid 511 resulting in a distinct 10 amino acid sequence at the C-terminus. This transcript variant is alternatively referred to as BAP2-alpha, short form, or variant S. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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