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AKAP12 (NM_144497) Human Untagged Clone
CAT＃: SC110079
AKAP12 (untagged)-Human A kinase (PRKA) anchor protein 12 (AKAP12), transcript variant 2
CNY 11,328.00
货期*
现货
规格
Product images
经常一起买 (4)
AKAP12 mouse monoclonal antibody,clone OTI1B6
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AKAP250; SSeCKS |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC110079 sequence for NM_144497 edited (data generated by NextGen Sequencing)
ATGCTGGGGACCATCACCATCACAGTTGGACAGAGAGACTCTGAAGATGTGAGCAAAAGA GACTCCGATAAAGAGATGGCTACTAAGTCAGCGGTTGTTCACGACATCACAGATGATGGG CAGGAGGAGACACCCGAAATAATCGAACAGATTCCTTCTTCAGAAAGCAATTTAGAAGAG CTAACACAACCCACTGAGTCCCAGGCTAATGATATTGGATTTAAGAAGGTGTTTAAGTTT GTTGGCTTTAAATTCACTGTGAAAAAGGATAAGACAGAGAAGCCTGACACTGTCCAGCTA CTCACTGTGAAGAAAGATGAAGGGGAGGGAGCAGCAGGGGCTGGCGACCACAAGGACCCC AGCCTTGGGGCTGGAGAAGCAGCATCCAAAGAAAGCGAACCCAAACAATCTACAGAGAAA CCCGAAGAGACCCTGAAGCGTGAGCAAAGCCACGCAGAAATTTCTCCCCCAGCCGAATCT GGCCAAGCAGTGGAGGAATGCAAAGAGGAAGGAGAAGAGAAACAAGAAAAAGAACCTAGC AAGTCTGCAGAATCTCCGACTAGTCCCGTGACCAGTGAAACAGGATCAACCTTCAAAAAA TTCTTCACTCAAGGTTGGGCCGGCTGGCGCAAAAAGACCAGTTTCAGGAAGCCGAAGGAG GATGAAGTGGAAGCTTCAGAGAAGAAAAAGGAACAAGAGCCAGAAAAAGTAGACACAGAA GAAGACGGAAAGGCAGAGGTTGCCTCCGAGAAACTGACCGCCTCCGAGCAAGCCCACCCA CAGGAGCCGGCAGAAAGTGCCCACGAGCCCCGGTTATCAGCTGAATATGAGAAAGTTGAG CTGCCCTCAGAGGAGCAAGTCAGTGGCTCGCAGGGACCTTCTGAAGAGAAACCTGCTCCG TTGGCGACAGAAGTGTTTGATGAGAAAATAGAAGTCCACCAAGAAGAGGTTGTGGCCGAA GTCCACGTCAGCACCGTGGAGGAGAGAACCGAAGAGCAGAAAACGGAGGTGGAAGAAACA GCAGGGTCTGTGCCAGCTGAAGAATTGGTTGAAATGGATGCAGAACCTCAGGAAGCTGAA CCTGCCAAGGAGCTGGTGAAGCTCAAAGAAACGTGTGTTTCCGGAGAGGACCCTACACAG GGAGCTGACCTCAGTCCTGATGAGAAGGTGCTGTCCAAACCCCCCGAAGGCGTTGTGAGT GAGGTGGAAATGCTGTCATCACAGGAGAGAATGAAGGTGCAGGGAAGTCCACTAAAGAAG CTTTTTACCAGCACTGGCTTAAAAAAGCTTTCTGGAAAGAAACAGAAAGGGAAAAGAGGA GGAGGAGACGAGGAATCAGGGGAGCACACTCAGGTTCCAGCCGATTCTCCGGACAGCCAG GAGGAGCAAAAGGGCGAGAGCTCTGCCTCATCCCCTGAGGAGCCCGAGGAGATCACGTGT CTGGAAAAGGGCTTAGCCGAGGTGCAGCAGGATGGGGAAGCTGAAGAAGGAGCTACTTCC GATGGAGAGAAAAAAAGAGAAGGTGTCACTCCCTGGGCATCATTCAAAAAGATGGTGACG CCCAAGAAGCGTGTTAGACGGCCTTCGGAAAGTGATAAAGAAGATGAGCTGGACAAGGTC AAGAGCGCTACCTTGTCTTCCACCGAGAGCACAGCCTCTGAAATGCAAGAAGAAATGAAA GGGAGCGTGGAAGAGCCAAAGCCGGAAGAACCAAAGCGCAAGGTGGATACCTCAGTATCT TGGGAAGCTTTAATTTGTGTGGGATCATCCAAGAAAAGAGCAAGGAGAGGGTCCTCTTCT GATGAGGAAGGGGGACCAAAAGCAATGGGAGGAGACCACCAGAAAGCTGATGAGGCCGGA AAAGACAAAGAGACGGGGACAGACGGGATCCTTGCTGGTTCCCAAGAACATGATCCAGGG CAGGGAAGTTCCTCCCCGGAGCAAGCTGGAAGCCCTACCGAAGGGGAGGGCGTTTCCACC TGGGAGTCATTTAAAAGGTTAGTCACGCCAAGAAAAAAATCAAAGTCCAAGCTGGAAGAG AAAAGCGAAGACTCCATAGCTGGGTCTGGTGTAGAACATTCCACTCCAGACACTGAACCC GGTAAAGAAGAATCCTGGGTCTCAATCAAGAAGTTTATTCCTGGACGAAGGAAGAAAAGG CCAGATGGGAAACAAGAACAAGCCCCTGTTGAAGACGCAGGGCCAACAGGGGCCAACGAA GATGACTCTGATGTCCCGGCCGTGGTCCCTCTGTCTGAGTATGATGCTGTAGAAAGGGAG AAAATGGAGGCACAGCAAGCCCAAAAAAGCGCAGAGCAGCCCGAGCAGAAGGCAGCCACT GAGGTGTCCAAGGAGCTCAGCGAGAGTCAGGTTCATATGATGGCAGCAGCTGTCGCTGAC GGGACGAGGGCAGCTACCATTATTGAAGAAAGGTCTCCTTCTTGGATATCTGCTTCAGTG ACAGAACCTCTTGAACAAGTAGAAGCTGAAGCCGCACTGTTAACTGAGGAGGTATTGGAA AGAGAAGTAATTGCAGAAGAAGAACCCCCCACGGTTACTGAACCTCTGCCAGAGAACAGA GAGGCCCGGGGCGACACGGTCGTTAGTGAGGCGGAATTGACCCCCGAAGCTGTGACAGCT GCAGAAACTGCAGGGCCATTGGGTGCCGAAGAAGGAACCGAAGCATCTGCTGCTGAAGAG ACCACAGAAATGGTGTCAGCAGTCTCCCAGTTAACCGACTCCCCAGACACCACAGAGGAG GCCACTCCGGTGCAGGAGGTGGAAGGTGGCGTACCTGACATAGAAGAGCAAGAGAGGCGG ACTCAAGAGGTCCTCCAGGCAGTGGCAGAAAAAGTGAAAGAGGAATCCCAGCTGCCTGGC ACCGGTGGGCCAGAAGATGTGCTTCAGCCTGTGCAGAGAGCAGAGGCAGAAAGACCAGAA GAGCAGGCTGAAGCGTCGGGTCTGAAGAAAGAGACGGATGTAGTGTTGAAAGTAGATGCT CAGGAGGCAAAAACTGAGCCTTTTACACAAGGGAAGGTGGTGGGGCAGACCACCCCAGAA AGCTTTGAAAAAGCTCCTCAAGTCACAGAGAGCATAGAGTCCAGTGAGCTTGTAACCACT TGTCAAGCCGAAACCTTAGCTGGGGTAAAATCACAGGAGATGGTGATGGAACAGGCTATC CCCCCTGACTCGGTGGAAACCCCTACAGACAGTGAGACTGATGGAAGCACCCCCGTAGCC GACTTTGACGCACCAGGCACAACCCAGAAAGACGAGATTGTGGAAATCCATGAGGAGAAT GAGGTCGCATCTGGTACCCAGTCAGGGGGCACAGAAGCAGAGGCAGTTCCTGCACAGAAA GAGAGGCCTCCAGCACCTTCCAGTTTTGTGTTCCAGGAAGAAACTAAAGAACAATCAAAG ATGGAAGACACTCTAGAGCATACAGATAAAGAGGTGTCAGTGGAAACTGTATCCATTCTG TCAAAGACTGAGGGGACTCAAGAGGCTGACCAGTATGCTGATGAGAAAACCAAAGACGTA CCATTTTTCGAAGGACTTGAGGGGTCTATAGACACAGGCATAACAGTCAGTCGGGAAAAG GTCACTGAAGTTGCCCTTAAAGGTGAAGGGACAGAAGAAGCTGAATGTAAAAAGGATGAT GCTCTTGAACTGCAGAGTCACGCTAAGTCTCCTCCATCCCCCGTGGAGAGAGAGATGGTA GTTCAAGTCGAAAGGGAGAAAACAGAAGCAGAGCCAACCCATGTGAATGAAGAGAAGCTT GAGCACGAAACAGCTGTTACCGTATCTGAAGAGGTCAGTAAGCAGCTCCTCCAGACAGTG AATGTGCCCATCATAGATGGGGCAAAGGAAGTCAGCAGTTTGGAAGGAAGCCCTCCTCCC TGCCTAGGTCAAGAGGAGGCAGTATGCACCAAAATTCAAGTTCAGAGCTCTGAGGCATCA TTCACTCTAACAGCGGCTGCAGAGGAGGAAAAGGTCTTAGGAGAAACTGCCAACATTTTA GAAACAGGTGAAACGTTGGAGCCTGCAGGTGCACATTTAGTTCTGGAAGAGAAATCCTCT GAAAAAAATGAAGACTTTGCCGCTCATCCAGGGGAAGATGCTGTGCCCACAGGGCCCGAC TGTCAGGCAAAATCGACACCAGTGATAGTATCTGCTACTACCAAGAAAGGCTTAAGTTCG GACCTGGAAGGAGAGAAAACCACATCACTGAAGTGGAAGTCAGATGAAGTCGATGAGCAG GTTGCTTGCCAGGAGGTCAAAGTGAGTGTAGCAATTGAGGATTTAGAGCCTGAAAATGGG ATTTTGGAACTTGAGACCAAAAGCAGTAAACTTGTCCAAAACATCATCCAGACAGCCGTT GACCAGTTTGTACGTACAGAAGAAACAGCCACCGAAATGTTGACGTCTGAGTTACAGACA CAAGCTCACGTGATAAAAGCTGACAGCCAGGACGCTGGACAGGAAACGGAGAAAGAAGGA GAGGAACCTCAGGCCTCTGCACAGGATGAAACACCAATTACTTCAGCCAAAGAGGAGTCA GAGTCAACCGCAGTGGGACAAGCACATTCTGATATTTCCAAAGACATGAGTGAAGCCTCA GAAAAGACCATGACTGTTGAGGTAGAAGGTTCCACTGTAAATGATCAGCAGCTGGAAGAG GTCGTCCTCCCATCTGAGGAAGAGGGAGGTGGAGCTGGAACAAAGTCTGTGCCAGAAGAT GATGGTCATGCCTTGTTAGCAGAAAGAATAGAGAAGTCACTAGTTGAACCGAAAGAAGAT GAAAAAGGTGATGATGTTGATGACCCTGAAAACCAGAACTCAGCCCTGGCTGATACTGAT GCCTCAGGAGGCTTAACCAAAGAGTCCCCAGATACAAATGGACCAAAACAAAAAGAGAAG GAGGATGCCCAGGAAGTAGAATTGCAGGAAGGAAAAGTGCACAGTGAATCAGATAAAGCG ATCACACCCCAAGCACAGGAGGAGTTACAGAAACAAGAGAGAGAATCTGCAAAGTCAGAA CTTACAGAATCTTAA Clone variation with respect to NM_144497.2 4200 c=>g >OriGene 5' read for NM_144497 unedited
GCGGCCGGCGAATTCGCACGAGGGTCTGGGCGCTCAGTCCGCTCTGATCCCGCCGAACCA CCTGCGGTTGGCAGGCAGGAGACTAGGCGTCTGCCGGGGAGGGCAGGGACCCGCTAAGCT GATCTCCTGTACAGTAGTGCTACTTAAAATATGCTGGGGACCATCACCATCACAGTTGGA CAGAGAGACTCTGAAGATGTGAGCAAAAGAGACTCCGATAAAGAGATGGCTACTAAGTCA GCGGTTGTTCACGACATCACAGATGATGGGCAGGAGGAGACACCCGAAATAATCGAACAG ATTCCTTCTTCAGAAAGCAATTTAGAAGAGCTAACACAACCCACTGAGTCCCAGGCTAAT GATATTGGATTTAAGAAGGTGTTTAAGTTTGTTGGCTTTAAATTCACTGTGAAAAAGGAT AAGACAGAGAAGCCTGACACTGTCCAGCTACTCACTGTGAAGAAAGATGAAGGGGAGGGA GCAGCAGGGGCTGGCGACCACAAGGACCCCAGCCTTGGGGCTGGAGAAGCAGCATCCAAA GAAAGCGAACCCAAACAATCTACAGAGAAACCCGAAGAGACCCTGAAGCGTGAGCAAAGC CACGCAGAAATTTCTCCCCCAGCCGAATCTGGCCAAGCAGTGGAGGAATGCAAAGAGGAA GGAGAAGAGAAACAAGAANAAGAAACCTAGCAGTCTGCAGAATCTCCGACTAGTCCCGTG ACCAGTGANACAGGATCAACCTTCANAAAATTCTTCACTCAAGGNTGGGCCNGNCTGGCG CAAAAAGACCAGTTTCAGGAANCCCGAGGAGGATNNGAATGGAAGCTTCANAGAAGAAAA GGGAACANGAGCCNGNANNAGTNNACACAGAAAAGACGGAAAGGCCANAGGTTA >OriGene 3' read for NM_144497 unedited
TTTACGGAATTCTATGNNACCGCGGCCGCAATCTANNATCGAGTTTTTTTTTTTTTTTTT TTTTTTTTTTTAAGTGAAGCAAATATTTTATTTAAATCAGTCGTCAAATCACAACTTATC CAAATGAATGTGTTGCAACATTGTTCTTAAAAGAATGGCACAAATATGGCACAAACACAA TCCAGTATCTATCAAAATACCATTTGTAAAGAACCTGACTTATTTCATGCCATGTGTGAA TGCAGTCCAGCATATAAGAGTAGAATCAAAAACTTACAACAATTCTTTTCTTCATAACAT ATAAAACATATTCACTACTTTGCCTCAGGATTAAGCACACTTATCGGTCCAAACAACCAT AACAAGTAGGAAAAAGGATGTAAAGTTAATTTGCTACCAGAATATAACTTCTTTCTAACC TCCACTGGGTTAGAAAGAAAAATTTCCCAATGACAATAGAACATTCTGTATGTTTCAAAA TGCTTTTTAGTTTTAGCACACTCCGTGTAATAGGAAAGTGACCAATTTCAGAGTACCACT AAATATGGACCTCAATCATTAGTGAATTTTAAAGAATTGTACCTTGATCAGGAATGTTAC ATCTAGGAGGCTCTGTTTTTCGTGGGTTATATAACTGAAGCTTAAAGCTCCCCAAGCCTG CACTATGGCACATGCCCCATCATATACTGTGTGATACAAAAAACATGTAGTATCCTGCAC ATTTCCCTTAACATTAAGAAAAAAATATTCCATAGATACCGGAGGACTACTTTAAACATA CATATAAATATGTAAAGGATGATACCTCCAGTTTCAGAAACAGAACTAGGTATTGCCCAA CTCCATTTTCAGGTTAAAAATTTTAGGACCCTTAATCAGA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_144497 |
| Insert Size | 6000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_144497.1, NP_653080.1 |
| RefSeq Size | 6287 bp |
| RefSeq ORF | 5055 bp |
| Locus ID | 9590 |
| UniProt ID | Q02952 |
| Domains | PkinA_anch |
| Protein Families | Druggable Genome |
| Gene Summary | The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) has an alternate 5' segment, compared to variant 1, that results in a distinct 5' UTR and 5' coding region. The resulting isoform (2) has a distinct N-terminus and is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. |
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