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DR5 (TNFRSF10B) (NM_147187) Human Untagged Clone
CAT＃: SC109989
TNFRSF10B (untagged)-Human tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 2
CNY 6,650.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_147187 edited
ATAAATCAGCACGCGGCCGGAGAACCCCGCAATCTCTGCGCCCACAAAATACACCGACGA TGCCCGATCTACTTTAAGGGCTGAAACCCACGGGCCTGAGAGACTATAAGAGCGTTCCCT ACCGCCATGGAACAACGGGGACAGAACGCCCCGGCCGCTTCGGGGGCCCGGAAAAGGCAC GGCCCAGGACCCAGGGAGGCGCGGGGAGCCAGGCCTGGGCTCCGGGTCCCCAAGACCCTT GTGCTCGTTGTCGCCGCGGTCCTGCTGTTGGTCTCAGCTGAGTCTGCTCTGATCACCCAA CAAGACCTAGCTCCCCAGCAGAGAGCGGCCCCACAACAAAAGAGGTCCAGCCCCTCAGAG GGATTGTGTCCACCTGGACACCATATCTCAGAAGACGGTAGAGATTGCATCTCCTGCAAA TATGGACAGGACTATAGCACTCACTGGAATGACCTCCTTTTCTGCTTGCGCTGCACCAGG TGTGATTCAGGTGAAGTGGAGCTAAGTCCCTGCACCACGACCAGAAACACAGTGTGTCAG TGCGAAGAAGGCACCTTCCGGGAAGAAGATTCTCCTGAGATGTGCCGGAAGTGCCGCACA GGGTGTCCCAGAGGGATGGTCAAGGTCGGTGATTGTACACCCTGGAGTGACATCGAATGT GTCCACAAAGAATCAGGCATCATCATAGGAGTCACAGTTGCAGCCGTAGTCTTGATTGTG GCTGTGTTTGTTTGCAAGTCTTTACTGTGGAAGAAAGTCCTTCCTTACCTGAAAGGCATC TGCTCAGGTGGTGGTGGGGACCCTGAGCGTGTGGACAGAAGCTCACAACGACCTGGGGCT GAGGACAATGTCCTCAATGAGATCGTGAGTATCTTGCAGCCCACCCAGGTCCCTGAGCAG GAAATGGAAGTCCAGGAGCCAGCAGAGCCAACAGGTGTCAACATGTTGTCCCCCGGGGAG TCAGAGCATCTGCTGGAACCGGCAGAAGCTGAAAGGTCTCAGAGGAGGAGGCTGCTGGTT CCAGCAAATGAAGGTGATCCCACTGAGACTCTGAGACAGTGCTTCGATGACTTTGCAGAC TTGGTGCCCTTTGACTCCTGGGAGCCGCTCATGAGGAAGTTGGGCCTCATGGACAATGAG ATAAAGGTGGCTAAAGCTGAGGCAGCGGGCCACAGGGACACCTTGTACACGATGCTGATA AAGTGGGTCAACAAAACCGGGCGAGATGCCTCTGTCCACACCCTGCTGGATGCCTTGGAG ACGCTGGGAGAGAGACTTGCCAAGCAGAAGATTGAGGACCACTTGTTGAGCTCTGGAAAG TTCATGTATCTAGAAGGTAATGCAGACTCTGCCATGTCCTAAGTGTGATTCTCTTCAGGA AGTCAGACCTTCCCTGGTTTACCTTTTTTCTGGAAAAAGCCCAACTGGACTCCAGTCAGT AGGAAAGTGCCACAATTGTCACATGACCGGTACTGGAAGAAACTCTCCCATCCAACATCA CCCAGTGGATGGAACATCCTGTAACTTTTCACTGCACTTGGCATTATTTTTATAAGCTGA ATGTGATAATAAGGACACTATGGAAATGTCTGGATCATTCCGTTTGTGCGTACTTTGAGA TTTGGTTTGGGATGTCATTGTTTTCACAGCACTTTTTTATCCTAATGTAAATGCTTTATT TATTTATTTGGGCTACATTGTAAGATCCATCTACACAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_147187 unedited
ACTATAGGCGGCCGCGNAATTCGCACGAGGATAAATCAGCACGCGGCCGGAGAACCCCGC AATCTCTGCGCCCACAAAATACACCGACGATGCCCGATCTACTTTAAGGGCTGAAACCCA CGGGCCTGAGAGACTATAAGAGCGTTCCCTACCGCCATGGAACAACGGGGACAGAACGCC CCGGCCGCTTCGGGGGCCCGGAAAAGGCACGGCCCAGGACCCAGGGAGGCGCGGGGAGCC AGGCCTGGGCTCCGGGTCCCCAAGACCCTTGTGCTCGTTGTCGCCGCGGTCCTGCTGTTG GTCTCAGCTGAGTCTGCTCTGATCACCCAACAAGACCTAGCTCCCCAGCAGAGAGCGGCC CCACAACAAAAGAGGTCCAGCCCCTCAGAGGGATTGTGTCCACCTGGACACCATATCTCA GAAGACGGTAGAGATTGCATCTCCTGCAAATATGGACAGGACTATAGCACTCACTGGAAT GACCTCCTTTTCTGCTTGCGCTGCACCAGGTGTGATTCAGGTGAAGTGGAGCTAAGTCCC TGCACCACGACCAGAAACACAGTGGTGTCAGTGCGAAGAAGGCACCTTCCGGGAAGAAGA ATTCTCTGAGATGTGCCGGGAAGTGCCGCACAGGCTGTCCCCAGAGGGATGGTCAAGGGT CNGGTGATGGTACACCCTGGCATGACATCCNAATGTGTCCACAAAGAATCAGGCATCATC ATAGGAGTCACAGTTGCANNCGTAGTCTTGATNGGGGGCTTGGGTTTTGTTGGCAAGTCT TTCCTGGGGAAAAAAAGGCCTTCCTTACCTGAAGGCATTGCTCAGGGGGGGGGGGGGGGG GGACCCTGAGCGTGTGGACAGAAACTAACAAGACTGGGGGGCTGGGGACAA >OriGene 3' read for NM_147187 unedited
TTGGACCGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTGTGTAGATGG ATCTTACAATGTAGCCCAAATAAATAAATAAAGCATTTACATTAGGATAAAAAAGTGCTG TGAAAACAATGACATCCCAAACCAAATCTCAAAGTACGCACAAACGGAATGATCCAGACA TTTCCATAGTGTCCTTATTATCACATTCAGCTTATAAAAATAATGCCAAGTGCAGTGAAA AGTTACAGGATGTTCCATCCACTGGGTGATGTTGGATGGGAGAGTTTCTTCCAGTACCGG TCATGTGACAATTGTGGCACTTTCCTACTGACTGGAGTCCAGTTGGGCTTTTTCCAGAAA AAAGGTAAACCAGGGAAGGTCTGACTTCCTGAAGAGAATCACACTTAGGACATGGCAGAG TCTGCATTACCTTCTAGATACATGAACTTTCCAGAGCTCAACAAGTGGTCCTCAATCTTC TGCTTGGCAAGTCTCTCTCCCAGCGTCTCCAAGGCATCCAGCAGGGTGTGGACAGAGGCA TCTCGCCCGGTTTTGTTGACCCACTTTATCAGCATCGTGTACAAGGTGTCCCTGTGGCCC GCTGCCTCAGCTTTAGCCACCTTTATCTCATTGTCCATGAGGCCCAACTTCCTCATGAGC GGCTCCCAGGAGTCAAAGGGCACCAAGTCTGCAAAGTCATCGAAGCACTGTCTCAGAGTC TCAGTGGGATCACCTTCATTTGCTGGAACCAGCAGCCTCCTCCTCTGAGACCTTTCAGCT TCTGCCGGNTCCAGCAGATGCTCCTGACTCCCGGGGGACACATGNTGACACCTGTTGGCT CTGCTGGCTNCTGGACTTCCATTNTCTGCTCAAGGACCTGGGTGGGGCTGCAGAACTCAC GATCTCATTGAGGACATTGNCTTCAGCCCCNAGTCGTTGTGAGCTCTGTCCCACGCTCAG GNTCCCCACACCACTGAGCAGAGCG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_147187 |
| Insert Size | 4500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_147187.1, NP_671716.1 |
| RefSeq Size | 4073 bp |
| RefSeq ORF | 1236 bp |
| Locus ID | 8795 |
| UniProt ID | O14763 |
| Domains | DEATH, TNFR |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Apoptosis, Cytokine-cytokine receptor interaction, Natural killer cell mediated cytotoxicity, p53 signaling pathway |
| Gene Summary | The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009] Transcript Variant: This variant (2) lacks an in-frame coding segment compared to variant 1. The resulting isoform (2) lacks an internal region, as compared to isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219808 | TNFRSF10B (Myc-DDK-tagged)-Human tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 2 |
CNY 3,656.00 |
|
| RC219808L1 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 2, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC219808L2 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC219808L3 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC219808L4 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 2, mGFP tagged |
CNY 6,056.00 |
|
| RG219808 | TNFRSF10B (tGFP-tagged) - Human tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 2 |
CNY 5,256.00 |
