Kv beta 1 (KCNAB1) (NM_172159) Human Untagged Clone
CAT#: SC109907
KCNAB1 (untagged)-Human potassium voltage-gated channel, shaker-related subfamily, beta member 1 (KCNAB1), transcript variant 3
CNY 3,656.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | AKR6A3; hKvb3; hKvBeta3; KCNA1B; KV-BETA-1; Kvb1.3 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC109907 sequence for NM_172159 edited (data generated by NextGen Sequencing)
ATGCAAGTCTCCATAGCCTGCACAGAGCACAATTTGAAGAGTCGGAATGGTGAGGACCGA CTTCTGAGCAAGCAGAGCTCCACCGCCCCCAATGTGGTGAACGCAGCCCGGGCCAAATTC CGCACGGTCGCTATCATCGCGCGCAGCCTGGGGACGTTCACGCCTCAGCATCACATTTCT CTCAAAGAGTCCACCGCAAAGCAGACTGGCATGAAATATAGGAATCTTGGAAAATCAGGA CTCAGAGTTTCTTGCTTGGGTCTTGGAACATGGGTGACATTTGGAGGTCAAATTTCAGAT GAGGTTGCTGAACGGCTGATGACCATCGCCTATGAAAGTGGTGTTAACCTCTTTGATACT GCCGAAGTCTATGCTGCTGGAAAGGCTGAAGTGATTCTGGGGAGCATCATCAAGAAGAAA GGCTGGAGGAGGTCCAGTCTGGTCATAACAACCAAACTCTACTGGGGTGGAAAAGCTGAA ACAGAAAGAGGGCTGTCAAGAAAGCATATTATTGAAGGATTGAAGGGCTCCCTCCAGAGG CTGCAGCTCGAGTATGTGGATGTGGTCTTTGCAAATCGACCGGACAGTAACACTCCCATG GAAGAAATTGTCCGAGCCATGACACATGTGATAAACCAAGGCATGGCGATGTACTGGGGC ACCTCGAGATGGAGTGCTATGGAGATCATGGAAGCCTATTCTGTAGCAAGACAGTTCAAT ATGATCCCACCGGTCTGTGAACAAGCTGAGTACCATCTTTTCCAGAGAGAGAAAGTGGAG GTCCAGCTGCCAGAGCTCTACCACAAAATAGGTGTTGGCGCAATGACATGGTCTCCACTT GCCTGTGGAATCATCTCAGGAAAATACGGAAACGGGGTGCCTGAAAGTTCCAGGGCTTCA CTGAAGTGCTACCAGTGGTTGAAAGAAAGAATTGTAAGTGAAGAAGGGAGAAAACAGCAA AACAAGCTAAAAGACCTTTCCCCAATTGCGGAGCGTCTGGGATGCACACTACCTCAGCTA GCTGTTGCGTGGTGCCTGAGAAATGAAGGTGTGAGTTCTGTGCTCCTGGGATCATCCACT CCTGAACAACTCATTGAAAACCTTGGTGCCATTCAGGTTCTCCCAAAGATGACATCACAT GTGGTAAATGAGATTGATAACATACTGCGCAACAAGCCCTACAGCAAGAAGGACTATAGA TCATAA Clone variation with respect to NM_172159.3 >OriGene 5' read for NM_172159 unedited
GATTTTGTAATCCGACTTACTATAGGGCGGCCGCGAATTCGGCACGAGGGGAGCAAGGAG GGCTTAAAAGAAAAGCGGAAATCCCCGCAACTGCTCAACCTCTCGTGACTGCCTGTGTTC TGGGGTTCTGAGAGGGACCGTGCGCTGCCTGGGGAAGCAATGCAAGTCTCCATAGCCTGC ACAGAGCACAATTTGAAGAGTCGGAATGGTGAGGACCGACTTCTGAGCAAGCAGAGCTCC ACCGCCCCCAATGTGGTGAACGCAGCCCGGGCCAAATTCCGCACGGTCGCTATCATCGCG CGCAGCCTGGGGACGTTCACGCCTCAGCATCACATTTCTCTCAAAGAGTCCACCGCAAAG CAGACTGGCATGAAATATAGGAATCTTGGAAAATCAGGACTCAGAGTTTCTTGCTTGGGT CTTGGAACATGGGTGACATTTGGAGGTCAAATTTCAGATGAGGTTGCTGAACGGCTGATG ACCATCGCCTATGAAAGTGGTGTTAACCTCTTTGATACTGCCGAAGTCTATGCTGCTGGA AAGGCTGAAGTGATTCTGGGGAGCATCATCAAGAAGAAAGGCTGGAGGAGGTCCAGTCTG GTCATAACAACCAAACTCTACTGGGGTGGAAAAGCTGAAACAGACAGAGGGCTGTCAAGA AAGCATATTATTGAAGGATTGAAGGGCTCCCTTCCAGAGCTGCAGCTCGAGTATGTGGAT GTGGTCTGTGCAAATCGACCTGACAGTAACACTCCCATGGAAGAAATGTCCGAGCCATGA CACATGTGATAAACCTAAGCATGGCGATGTACTGAGGCACCCTCAGATGCAGTGCTATGG AGATCATGGCAGCCTATTCTGTAGCAGACAGCTCATATGATCCCACGGTCTGTGAACAGC TGAGTACATCTTTTCANAAGAGAAGAGGAGTCCAGCTGCCAGACTCTACACAACTAGTGT NGGCGCATGACTGTNCTCACTGCTGTGGACATCTCAGAAATCG >OriGene 3' read for NM_172159 unedited
TTGTTACATTATGNACGCGGCCGCATTCTANGATCGAGTTTTTTTTTTTTTTTTTTAAAA TTGAATGCACAAAATGCTTTTATTACTCTAAGCAAAATAAATCAATCAAATCACATTTCC CATTAGACAGCACCTCAGCTCCTCTATACATACAGCAGTTCGCTGGATTGAATACACAAT GAACAACTGAAAATGATCAATTTCCATCATTCTGATAACACGGGCAAAAAATTCAAACTC TCTGTTAGAATACAGGTACTAGTAATCAAAAAGAAAATTTCTTGATATCTCCCACTAGCA TTTTCAGATTTAGAATTTAACCATGAAGTACATATCTAGAACTAATGACAGAAAATCGCA TTTTAAAATAATATTACAGTTCTTCTGTAAACCTCAGAGTGATTTCTGTGTGGGGAACTT GCTGACCAGAAAATTAAATGAGAATTTTGTACATCCTCAGATAGCCAAATAGAGTTAAAG GGCCACTCCCACACCACCCCCTTCAAAAAAAAAAAAACATGTTTTCTCTCTTTTTACAGA TATTGACACAGTATAGTCTCACAATTTTTCTCAAGTGGGATATTAATGAGGGTAAGTAGC CAATAGTGGCAGGGCTAGATACACCTCAGATTTCGAGTGCAACAAGGGTAAGCCCCATTA ATCCATGCAAAGAACTTTCATGCATATAGTTTAGTGCATATAATATGATTATAGAACCAG AAGTTCTTTCTTTAACATTTTGCTTTTCACTAGGCAAGTTAATTTACCCAGCATATTCTG AATAGTGACATAGCATTTTTCACAAAGCCAGTGGTTGACTTTCATGTTAACAATGCCCTC AAAATACCAAACATTATATTATAAAATCCCAGTGCTAATTAAACATGAACATTTGCCTTC C |
Restriction Sites | NotI-NotI |
ACCN | NM_172159 |
Insert Size | 3200 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_172159.2, NP_751891.1 |
RefSeq Size | 4094 bp |
RefSeq ORF | 1206 bp |
Locus ID | 7881 |
UniProt ID | Q14722 |
Protein Families | Druggable Genome, Ion Channels: Other |
Gene Summary | Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes distinct isoforms which are encoded by alternatively spliced transcript variants of this gene. Some of these isoforms are beta subunits, which form heteromultimeric complexes with alpha subunits and modulate the activity of the pore-forming alpha subunits. [provided by RefSeq, Apr 2015] Transcript Variant: This variant (3) has an alternate 5' sequence including the 5' UTR and the 5' coding region, as compared to variant 1. It encodes isoform 3, also known as kvb1.3, which has a shorter and distinct N-terminus than isoform 1. |
Documents
Product Manuals |
FAQs |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC207384 | KCNAB1 (Myc-DDK-tagged)-Human potassium voltage-gated channel, shaker-related subfamily, beta member 1 (KCNAB1), transcript variant 3 |
CNY 3,656.00 |
|
RC207384L1 | Lenti ORF clone of Human potassium voltage-gated channel, shaker-related subfamily, beta member 1 (KCNAB1), transcript variant 3, Myc-DDK-tagged |
CNY 6,056.00 |
|
RC207384L2 | Lenti ORF clone of Human potassium voltage-gated channel, shaker-related subfamily, beta member 1 (KCNAB1), transcript variant 3, mGFP tagged |
CNY 5,890.00 |
|
RC207384L3 | Lenti ORF clone of Human potassium voltage-gated channel, shaker-related subfamily, beta member 1 (KCNAB1), transcript variant 3, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC207384L4 | Lenti ORF clone of Human potassium voltage-gated channel, shaker-related subfamily, beta member 1 (KCNAB1), transcript variant 3, mGFP tagged |
CNY 6,056.00 |
|
RG207384 | KCNAB1 (tGFP-tagged) - Human potassium voltage-gated channel, shaker-related subfamily, beta member 1 (KCNAB1), transcript variant 3 |
CNY 5,256.00 |
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