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UNG (NM_080911) Human Untagged Clone
CAT＃: SC109875
UNG (untagged)-Human uracil-DNA glycosylase (UNG), transcript variant 2
CNY 3,600.00
Product images
CNY 1,999.00
CNY 2,700.00
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DGU; HIGM4; HIGM5; UDG; UNG1; UNG2; UNG15 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_080911, the custom clone sequence may differ by one or more nucleotides
ATGATCGGCCAGAAGACGCTCTACTCCTTTTTCTCCCCCAGCCCCGCCAGGAAGCGACACGCCCCCAGCC CCGAGCCGGCCGTCCAGGGGACCGGCGTGGCTGGGGTGCCTGAGGAAAGCGGAGATGCGGCGGCCATCCC AGCCAAGAAGGCCCCGGCTGGGCAGGAGGAGCCTGGGACGCCGCCCTCCTCGCCGCTGAGTGCCGAGCAG TTGGACCGGATCCAGAGGAACAAGGCCGCGGCCCTGCTCAGACTCGCGGCCCGCAACGTGCCCGTGGGCT TTGGAGAGAGCTGGAAGAAGCACCTCAGCGGGGAGTTCGGGAAACCGTATTTTATCAAGCTAATGGGATT TGTTGCAGAAGAAAGAAAGCATTACACTGTTTATCCACCCCCACACCAAGTCTTCACCTGGACCCAGATG TGTGACATAAAAGATGTGAAGGTTGTCATCCTGGGACAGGATCCATATCATGGACCTAATCAAGCTCACG GGCTCTGCTTTAGTGTTCAAAGGCCTGTTCCGCCTCCGCCCAGTTTGGAGAACATTTATAAAGAGTTGTC TACAGACATAGAGGATTTTGTTCATCCTGGCCATGGAGATTTATCTGGGTGGGCCAAGCAAGGTGTTCTC CTTCTCAACGCTGTCCTCACGGTTCGTGCCCATCAAGCCAACTCTCATAAGGAGCGAGGCTGGGAGCAGT TCACTGATGCAGTTGTGTCCTGGCTAAATCAGAACTCGAATGGCCTTGTTTTCTTGCTCTGGGGCTCTTA TGCTCAGAAGAAGGGCAGTGCCATTGATAGGAAGCGGCACCATGTACTACAGACGGCTCATCCCTCCCCT TTGTCAGTGTATAGAGGGTTCTTTGGATGTAGACACTTTTCAAAGACCAATGAGCTGCTGCAGAAGTCTG GCAAGAAGCCCATTGACTGGAAGGAGCTGTGA >OriGene 5' read for NM_080911 unedited
CATTCGCGCTCGAGGCCACAGCGCGGTTCTAGCCTCGCCGGTTCCCGGGTGGCGCGCGTT CGCTGCCTCCTCAGCTCCAGGATGATCGGCCAGAAGACGCTCTACTCCTTTTTCTCCCCC AGCCCCGCCAGGAAGCGACACGCCCCCAGCCCCGAGCCGGCCGTCCAGGGGACTCGCGTG GCTGGGGTGCCTGAGGAAAGCTGAGATGCGGCGGCCATCCCAGCCAAGAAGGCCCCGGCT GGGCAGGAGGAGCCTGGGACTCCGCCCTCCTCGCCGCTGAGTGCCGAGCAGTTGGACCGG ATCCAGAGGAACAAGGCCGCGGCCCTGCTCAGACTCGCGGCCCGCAACGTGCCCGTGGGC TTTGGAGAGAGCTGGAAGAAGCACCTCAGCGGGGAGTTCGGGAAACCGTATTTTATCAAG CTAATGGGATTTGTTGCAGAAGACAGAAAGCATTACACTGTTTATCCACCCCCACACCAA GTCTTCACCTGGACCCAGATGTGTGACATAAAAGATGTGAAGGTTGTCATCCTGGGACAG GATCCATATCATGGACCTAATCAAGCTCACGGGCTCTGCTTTAGTGTTCAAAGGCCTGTT CCGCCTCCGCCCAGTTTGGACGAACATTATAAAGAGTTGTCTACAGACATAGAGGATTTT GTTCATTCTGACCATGGAGATTTATCTGGGTGGGCCCAGCAAAGTGTTCTGCTTCTCAAC GCTGTCCTCACGGGTCGGGCCCTTCAAGCCCACTCCCATTAAGAGCGAGCGTGGGACCAG TTCCTGGAGCAGTTGTGTACCTGGCTAATCAGAACTTCGAGGCCCTTGTTTCCTTGTCCG GGGCTCTTATGCTCAAAAAAGGCCGTGCCTTTGGTGGGAACGCGCC >OriGene 3' read for NM_080911 unedited
AGTGTTCAAAATCCATTTAAGGCTCGCGTAAAACCACTCTAACCCGNCTAAAGCAAAAAC AGCATTGCTAACAAGATCAAGGACGGAGGTGCAGACCCAATAAAGACCGTCTCTTAAAAA AAGGACTGGNGAAAAATATATATATATATATCTGCATGAGTACTTCTTAAAAAACTAAAA CTTTCCAGTGTTGCAGGAAAAAATATTTTTTTTGATTTCAGTCGGTTAAAAAAAACAGTA CTTGGCAGTCTGTGCTGCCTTAAAAACCCCAACTGGACATAACCCTAGGAGAAAATCACC CCACCCCATAAAGACAAAATTCCCTTTTCTCCTCTTCCTTGTTCAAATTCCACTGCTTAT TCCACCAACACCCAAGGAATAACAAGACCCAGCTTACTTCTCTCGGTCTCTTATCTGATA AAGCTCACAGCAATCTTAACCTCTACTACAATCAGGAAATTGAGCCCTAATTTCTGGGCC AGATTCTGGAAAGTTGCAAAACATCCTTATGCTGCGAGGGGCCTGAGGACTCCTTCAAAG ATCAAGGGGGCAGTGGAACTGGCAGAGACTGGCATGCCTGCCCTGCAGGCTGAGACAAGG GACCTTTCTAAGCAAAAACACCCAACATCTGTCACTGAAAGTCTAACCAGGCCAAACCAA GGAGCAGCAGGCGCCCAACTAGGCTGTGCCCTGAAAGTGCACATCTTCCCTGTTTCACAT AAGGCCAGGGAGATAAAAAAGCCAACTGAGTATTTGACCTCATCTGTCCTCTGGATATTT TAAGCCCAAACCCTTGTTGCAGAAAAAGAACTTTGGTCAAAGGGTACCCTTGTTTGTTGG GGTTGGAAACAAGTGCCTTTCCGGACAGCCTGGTTAATGGCTGCTTTCGGGAAACTTTTC CCCTTTAGCCGAGACCTTAAAGATTAATAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_080911 |
| Insert Size | 2300 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_080911.1, NP_550433.1 |
| RefSeq Size | 2053 bp |
| RefSeq ORF | 942 bp |
| Locus ID | 7374 |
| UniProt ID | P13051 |
| Domains | UDG |
| Protein Families | Druggable Genome, Stem cell - Pluripotency |
| Protein Pathways | Base excision repair, Primary immunodeficiency |
| Gene Summary | This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010] Transcript Variant: This variant (2) uses an upstream promoter and an alternate splice site for exon 1B when compared to variant 1. It encodes the nuclear UNG2 isoform, which has a different N-terminal sequence than the UNG1 isoform. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222868 | UNG (Myc-DDK-tagged)-Human uracil-DNA glycosylase (UNG), transcript variant 2 |
CNY 3,600.00 |
|
| RC222868L1 | Lenti ORF clone of Human uracil-DNA glycosylase (UNG), transcript variant 2, Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC222868L2 | Lenti ORF clone of Human uracil-DNA glycosylase (UNG), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC222868L3 | Lenti ORF clone of Human uracil-DNA glycosylase (UNG), transcript variant 2, Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC222868L4 | Lenti ORF clone of Human uracil-DNA glycosylase (UNG), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG222868 | UNG (tGFP-tagged) - Human uracil-DNA glycosylase (UNG), transcript variant 2 |
CNY 5,200.00 |
