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TNXB (NM_032470) Human Untagged Clone
CAT＃: SC109841
TNXB (untagged)-Human tenascin XB (TNXB), transcript variant XB-S
CNY 4,936.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EDS3; EDSCLL; EDSCLL1; HXBL; TENX; TN-X; TNX; TNXB1; TNXB2; TNXBS; VUR8; XB; XBS |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC109841 sequence for NM_032470 edited (data generated by NextGen Sequencing)
ATGCGCCTCTCGTGGAGCGTGGCCCAGGGCCCCTTTGATTCCTTCGTGGTCCAGTATGAG GACACGAACGGGCAGCCCCAGGCCTTGCTCGTGGACGGCGACCAGAGCAAGATCCTCATC TCAGGCCTGGAGCCCAGCACCCCCTACAGGTTCCTCCTCTATGGCCTCCATGAAGGGAAG CGCCTGGGGCCCCTCTCAGCTGAGGGCACCACAGGGCTGGCTCCTGCTGGTCAGACCTCA GAGGAGTCAAGGCCCCGCCTGTCCCAGCTGTCTGTGACTGACGTGACCACCAGTTCACTG AGGCTCAACTGGGAGGCCCCACCGGGGGCCTTCGACTCCTTCCTGCTCCGCTTTGGGGTT CCATCACCAAGCACACTGGAGCCGCATCCGCGTCCACTGCTGCAGCGCGAGCTGATGGTG CCGGGGACGCGGCACTCGGCCGTGCTCCGGGACCTGCGTTCCGGGACTCTGTACAGCCTG ACACTGTATGGGCTGCGAGGACCCCACAAGGCCGACAGCATCCAGGGAACCGCCCGCACC CTCAGCCCAGTTCTGGAGAGCCCCCGTGACCTCCAATTCAGTGAAATCAGGGAGACCTCA GCCAAGGTCAACTGGATGCCCCCACCATCCCGGGCGGACAGCTTCAAAGTCTCCTACCAG CTGGCGGACGGAGGGGAGCCTCAGAGTGTGCAGGTGGATGGCCAGGCCCGGACCCAGAAA CTCCAGGGGCTGATCCCAGGCGCTCGCTATGAGGTGACCGTGGTCTCGGTCCGAGGCTTT GAGGAGAGTGAGCCTCTCACAGGCTTCCTCACCACGGTTCCTGACGGTCCCACACAGTTG CGTGCACTGAACTTGACCGAGGGATTCGCCGTGCTGCACTGGAAGCCCCCCCAGAATCCT GTAGACACCTATGACATCCAGGTCACAGCCCCTGGGGCCCCGCCTCTGCAGGCGGAGACC CCAGGCAGCGCGGTGGACTACCCCCTGCATGACCTTGTCCTCCACACCAACTACACCGCC ACAGTGCGTGGCCTGCGGGGCCCCAACCTCACTTCCCCAGCCAGCATCACCTTCACCACA GGGCTAGAGGCCCCTCGGGACTTGGAGGCCAAGGAAGTGACCCCCCGCACCGCCCTGCTC ACTTGGACTGAGCCCCCAGTCCGGCCCGCAGGCTACCTGCTCAGCTTCCACACCCCTGGT GGACAGACCCAGGAGATCCTGCTCCCAGGAGGGATCACATCTCACCAGCTCCTTGGCCTC TTTCCCTCCACCTCCTACAATGCACGGCTCCAGGCCATGTGGGGCCAGAGCCTCCTGCCG CCCGTGTCCACCTCTTTCACCACGGGTGGGCTGCGGATCCCCTTCCCCAGGGACTGCGGG GAGGAGATGCAGAACGGAGCCGGTGCCTCCAGGACCAGCACCATCTTCCTCAACGGCAAC CGCGAGCGGCCCCTGATCGTGTTTTGCGACATGGAGACTGATGGGGGCGGCTGGCTGGTG TTCCAGCGCCGCATGGATGGACAGACAGACTTCTGGAGGGACTGGGAGGACTATGCCCAT GGTTTTGGGAACATCTCTGGAGAGTTCTGGCTGGGCAATGAGGCCCTGCACAGCCTGACA CAGGCAGGTGACTACTCCATGCGCGTGGACCTGCGGGCTGGGGACGAGGCTGTGTTCGCC CAGTACGACTCCTTCCACGTAGACTCGGCTGCGGAGTACTACCGCCTCCACTTGGAGGGC TACCACGGCACCGCAGGGGACTCCATGAGCTACCACAGCGGCAGTGTCTTCTCTGCCCGT GATCGGGACCCCAACAGCTTGCTCATCTCCTGCGCTGTCTCCTACCGAGGGGCCTGGTGG TACAGGAACTGCCACTACGCCAACCTCAACGGGCTCTACGGGAGCACAGTGGACCATCAG GGAGTGAGCTGGTACCACTGGAAGGGCTTCGAGTTCTCGGTGCCCTTCACGGAAATGAAG CTGAGACCAAGAAACTTTCGCTCCCCAGCGGGGGGAGGCTGA Clone variation with respect to NM_032470.3 375 t=>a;903 g=>a;916 g=>a;1208 a=>c;1457 a=>t >OriGene 5' read for NM_032470 unedited
NNCCCNNNCCCCNNNNNCCNNNNNNCCTGTCAGATTTGTATACGATCATATAGGCGGCCG CGNAATTCGCACCAGCTGGGNATGACAGCCCCANAAAAGGACACACCAGCCCCAGAGTTA GCCCCAGAGGCCCCTGAGCCTCCTGAAGAGCCCCGCCTAGGAGTGCTGACCGTGACCGAC ACAACCCCAGACTCCATGCGCCTCTCGTGGAGCGTGGCCCAGGGCCCCTTTGATTCCTTC GTGGTCCAGTATGAGGACACGAACGGGCAGCCCCAGGCCTTGCTCGTGGACGGCGACCAG AGCAAGATCCTCATCTCAGGCCTGGAGCCCAGCACCCCCTACAGGTTCCTCCTCTATGGC CTCCATGAAGGGAAGCGCCTGGGGCCCCTCTCAGCTGAGGGCACCACAGGGCTGGCTCCT GCTGGTCAGACCTCAGAGGAGTCAAGGCCCCGCCTGTCCCAGCTGTCTGTGACTGACGTG ACCACCAGTTCACTGAGGCTCAACTGGGAGGCCCCACCGGGGGCCTTCGACTCCTTCCTG CTCCGCTTTGGGGTTCCATCACCAAGCACACTGGAGCCGCATCCGCGTCCACTGCTGCAG CGCGAGCTGATGGTGCCGGGGACGCGGCACTCGGCCGTGCTCCGGGACCTGCGTTCCGGG ACTCTGTACAGCCTGACACTGTATGGGCTGCGAGGACCCCACANGGCCGACAGCATCCAG GGAACCGNCCGCACCCTCAGCCCAGTTCTGGGAGAGCCCNCGTGACCTCCATTNCAGTGA AATCAGGGAGACCTCAGCCAAGGTCAACTGGATGCCCCCACATCCCGGGCGACAGCTTNC AAGTCTCCTACCGCTGGCGNACGNAGGGGAGCCTCANATGTGCCAGTGGATGGCCANNGC CCGNACCAGAACTCCAGGGCCTGA >OriGene 3' read for NM_032470 unedited
GGGGGGGGNNNNNNNNNNNNTTTTNNNNNAANAAAATCTTGNACCGCGCCGCATACTANG ATCGGTTTTTTTTTTTTTTTTTTTACCTCAGTTTCTCCTTTATTGCTCCCGTACGAACCG CTCCCCTCCCCCCTGTAAACACAGTGCTGCGAGATCGCTGGCAGAGAAGGCTTCCTCCAG CGGCTGGGTGGTGAAGGACCCTGGCTCTTCTCTCGGGGCGACCCCTCAGTGCTCGGCAGT CATACTGGGGTGCGAGAGAGGTGGGCAGCAGCTCAGCCTCCCCCCGCTGGGGAGCGAAAG TTTCTTGGTCTCAGCTTCATTTCCGTGAAGGGCACCGAGAACTCGAAGCCCTTCCAGTGG TACCAGCTCACTCCCTGATGGTCCACTGTGCTCCCGTAGAGCCCGTTGAGGTTGGCGTAG TGGCAGTTCCTGTACCACCAGGCCCCTCGGTAGGAGACAGCGCAGGAGATGAGCAAGCTG TTGGGGTCCCGATCACGGGCAGAGAAGACACTGCCGCTGTGGTAGCTCATGGAGTCCCCT GCGGTGCCGTGGTAGCCCTCCAAGTGGAGGCGGTAGTACTCCGCAGCCGAGTCTACGTGG AAGGAGTCGTACTGGGCGAACACAGCCTCGTCCCCAGCCCGCAGGTCCACGCGCATGGAG TAGTCACCTGCCTGTGTCAGGCTGTGCAGGNCCTCATTGCCCAGCCAGACTCTCCAGAGA TGTTCCCAAAAACATGGNCATAGTCCTCCCAGTCCCTCCAGAAGTCTGTCTGTCCATCCA TTGCGCGCTGGGACACCAGCCAGCCCGCCCCATCAGTCTCCATGTCGCAAACACGATCAN GGGCCCGCTCGCGTTTGCGTTGAGGAAAATGTGCCTGTCCTGNAGCCACCGGTCCGTCTG CATCTCTNCCGCAGTCTGGGGAAGGGGATCGCACCCACCCGTGTGAAAGAGGTGGACCCG GCGNNNAGAGCTCTGGCCCCATGCCTGGAACTGCATTGGAGAGGGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_032470 |
| Insert Size | 2390 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_032470.2, NP_115859.2 |
| RefSeq Size | 3129 bp |
| RefSeq ORF | 2022 bp |
| Locus ID | 7148 |
| UniProt ID | P22105 |
| Domains | FBG, FN3 |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | ECM-receptor interaction, Focal adhesion |
| Gene Summary | This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (XB-S) is transcribed from a cryptic internal promoter sequence and is substantially shorter than variant 3 at the 5' end. It encodes isoform 2, which is identical to the C-terminus of the full-length protein, isoform 3. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC220722 | TNXB (Myc-DDK-tagged)-Human tenascin XB (TNXB), transcript variant XB-S |
CNY 4,928.00 |
|
| RC220722L3 | Lenti ORF clone of Human tenascin XB (TNXB), transcript variant XB-S, Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC220722L4 | Lenti ORF clone of Human tenascin XB (TNXB), transcript variant XB-S, mGFP tagged |
CNY 7,700.00 |
|
| RG220722 | TNXB (tGFP-tagged) - Human tenascin XB (TNXB), transcript variant XB-S |
CNY 6,528.00 |
