ABCD4 (NM_020324) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	ABC41; EST352188; MAHCJ; P70R; P79R; PMP69; PXMP1L
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene ORF within SC109688 sequence for NM_020324 edited (data generated by NextGen Sequencing) ATGGCCAGCAAGCTCATCATCTCCCCGTTCACCCTCGTCTACTACACTTACCAGTGCTTC CAAAGCACAGGCTGGCTCGGGCCTGTGAGCATCTTCGGGTATTTCATCCTGGGGACCGTG GTGAACAAAACTTTGATGGGCCCCATTGTGATGAAGCTGGTGCATCAGGAGAAGCTGGAG GGAGATTTTAGGTTCAAGCACATGCAGATTCGGGTGAATGCGGAGCCTGCTGCTTTCTAC AGAGCTGGGCATGTGGAGCACATGAGGACAGACCGCAGGCTGCAGAGACTCCTTCAGACC CAGAGGGAGCTGATGTCCAAGGAGCTCTGGCTGTACATCGGCATCAACACCTTTGACTAT CTGGGCAGCATCCTGAGTTATGTTGTCATCGCAATCCCCATTTTCAGCGGGGTCTATGGA GACCTGAGTCCCGCAGAGCTTAGCACCCTGGTCAGCAAGAATGCCTTTGTGTGCATCTAC CTCATCAGCTGCTTCACCCAGCTAATCGACCTGTCCACGACGCTCTCAGATGTGGCTGGC TACACGCACAGAATTGGGCAGCTTCGGGAGACGCTTCTGGACATGTCCCTGAAGTCACAG GACTGCGAGATCCTGGGCGAGAGCGAGTGGGGCTTGGACACACCCCCAGGGTGGCCAGCG GCAGAGCCAGCAGACACAGCATTTCTCCTTGAGCGGGTCTCCATCTCTGCCCCCTCCTCT GACAAACCCCTAATCAAGGATCTGAGCCTAAAGATCTCCGAGGGACAGAGCCTGCTCATC ACAGGCAACACGGGCACTGGCAAGACCTCCTTGCTCCGGGTTCTAGGTGGCCTCTGGACG AGTACACGGGGCTCAGTGCAGATGCTGACGGACTTTGGGCCCCATGGGGTGCTATTCCTG CCACAAAAGCCATTCTTCACTGACGGGACCCTTCGGGAGCAGGTGATATATCCCCTGAAG GAGGTCTACCCCGACTCAGGTTCTGCCGATGATGAGAGGATCTTGAGGTTCTTGGAATTG GCAGGCCTGTCCAACTTGGTGGCAAGGACAGAGGGCCTGGACCAGCAGGTGGACTGGAAC TGGTATGATGTTCTGTCCCCGGGGGAGATGCAACGGCTCTCCTTTGCCCGACTCTTCTAC CTGCAGCCGAAGTACGCAGTGCTTGATGAAGCCACCAGTGCCCTGACAGAGGAAGTGGAG AGCGAGCTCTATCGCATCGGCCAGCAGCTGGGGATGACGTTCATCAGTGTGGGACATCGG CAGAGCCTTGAGAAGTTTCATTCCTTGGTTCTGAAACTCTGTGGAGGAGGAAGATGGGAG CTGATGAGAATCAAAGTGGAATGA Clone variation with respect to NM_020324.1 504 c=>a;1056 t=>c 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for NM_020324 unedited NGGTTCACATTTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGGCGGGGCC CGCGCCCGGAGCTGGCGCCAGGCCCAGGTTAGATCTGCAATTTCTCCAGCGGTTCCTGCA GATACTGAAGGTTTTGTTTCCTTCTTGGTCATCACAAAATGCCTTGATGTTCCTGACCCT TTTGTGCCTGACCCTACTGGAGCAATTTGTGATCTACCAGGTTGGCCTGATCCCCAGTCA GTACTATGGGGTCCTGGGAAACAAAGACTTGGAAGGGTTTAAGACTCTGACATTCCTGGC TGTCATGCTCATTGTTCTGAACTCCACGCTGAAGAGCTTTGATCAGTTCACCTGCAACCT GCTGTATGTGAGCTGGAGGAAGGACCTCACTGAGCACCTTCACCGCCTCTACTTCCGGGG CCGTGCGTACTACACCCTCAACGTGCTGCGGGATGACATCGATAACCCGGACCAGCGCAT CAGCCAGGACGTGGAGCGATTCTGCCGGCAGCTCAGCAGCATGGCCAGCAAGCTCATCAT CTCCCCGTTCACCCTCGTCTACTACACTTACCAGTGCTTCCAAAGCACAGGCTGGCTCGG GCCTGTGAGCATCTTCGGGTATTTCATCCTGGGGACCGTGGTGAACAAAACTTTGATGGG CCCCATTGTGATGAAGCTGGTGCATCAGGAGAAGCTGGAGGGAGATTTTAGGTTCAAGCA CATGCAGATTCGGGTGAATGCGGAGCCTGCTGCTTTCTACAGAGCTGGGCATGTGGAGCA CATGANGACAGACCGCNAGCTGCAGAGACTCCTTCAGACCCAGAGGGAGCTGATGTCCAA GGAGCTCTGGCTGTACATCGGCATCAACACCTTTGACTATCTGGGCAGCANCCTGAGTTA CGTTGTCATCGCAATCCCT 3' Read Nucleotide Sequence (showhide) >OriGene 3' read for NM_020324 unedited CTATGGACCCGCGGCCGCAATCTAGGATCGAGTTNTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTCTTTTTTTTTAAAAAAAAACAAAAAGCTGGAATTCTTTTTAATGGTTAAC TTTTCTTTGGAAAAAACTTATTAAAAAACTTAAATGGGCAGTTAAAGTTAAAAATCTATT GCTGCACAATTTAACTGATTAAAAGATTTCCAGATCTCTTGACTCCAAAAGTCATTTTTT TCATTTCTTACAAATCTCACACTTCCAAATTTCTCTTTACCAAACATGATCTGAAATCAT TTGTAGGTAATCAGCACTTCAAGCATATGGAGGCTTTGGCTGAGGCACCAAAGTCCTGGG AAACTGAACACTGGGAAATTCAGTGTCCCCCACAAAAACCTAAACCTGGGCTCAACCCAC CACTGCTAGGGGTCCTGCACAGGACCCATGTGGCTCCTGCCCGGGATCTATGGGGCGAAC CTGAGCTCGATCTTCGCTGTCAGTCCTCCTGGTCTCTCCTGAGGGCCGCCGACCCGCCAC AGTGTGGCTCTCCTTCCAAAAGCCAGAGCTTCATTCCACTTTGATTCTTATCAGCTCCCA TCTTCCTCCTCCCAGAGTTTCAGAACCAAGGAATGAAACTTCTCAAGGTTCTGCCGATTC CCCCACTGATAACGTCATCCCCACCTGCTGGCCGATGCGATAGAGCTCGTCCTCACTTCC TCTGCAAGGCACTGGTGCCTCATCAACCCCTGGCACTTCGGCTGAGGAAAAAGAGCGGGC AAAGAAACCGCTGCATTTCCCCCGGGACAGACATTTTACAACTTCATCCACCGGCTGGCC AGCCCTTGTCCTTGCCCCAAGTGGCAGGCTCGCAATCCAAAACTAAAACCTCTTATATTG CAAACCTGATCGGGACCCCCCTTAGGGAATATACCCCCCCCAGGCCCCCACGG
Restriction Sites	NotI-NotI
ACCN	NM_020324
Insert Size	2240 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_020324.1, NP_064720.1
RefSeq Size	2787 bp
RefSeq ORF	2787 bp
Locus ID	5826
Domains	ABC_tran, AAA
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	ABC transporters
Gene Summary	The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in several protein-coding and non-protein-coding variants. [provided by RefSeq, Jul 2017] Transcript Variant: This variant (3), as well as variant 13, encodes isoform c. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

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