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NFAT2 (NFATC1) (NM_172388) Human Untagged Clone
CAT＃: SC109490
NFATC1 (untagged)-Human nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (NFATC1), transcript variant 4
CNY 3,656.00
CNY 5,700.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | NF-ATC; NF-ATc1.2; NFAT2; NFATc |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_172388, the custom clone sequence may differ by one or more nucleotides
ATGCTGCAGCTTTTCATTGGGACGGCGGACGACCGCCTGCTGCGCCCGCACGCCTTCTACCAGGTGCACC GCATCACAGGGAAGACCGTGTCCACCACCAGCCACGAGGCCATCCTCTCCAACACCAAAGTCCTGGAGAT CCCACTCCTGCCGGAGAACAGCATGCGAGCCGTCATTGACTGTGCCGGAATCCTGAAACTCAGAAACTCC GACATTGAACTTCGGAAAGGAGAGACGGACATCGGGAGGAAGAACACACGGGTACGGCTGGTGTTCCGCG TTCACGTCCCGCAACCCAGCGGCCGCACGCTGTCCCTGCAGGTGGCCTCCAACCCCATCGAATGCTCCCA GCGCTCAGCTCAGGAGCTGCCTCTGGTGGAGAAGCAGAGCACGGACAGCTATCCGGTCGTGGGCGGGAAG AAGATGGTCCTGTCTGGCCACAACTTCCTGCAGGACTCCAAGGTCATTTTCGTGGAGAAAGCCCCAGATG GCCACCATGTCTGGGAGATGGAAGCGAAAACTGACCGGGACCTGTGCAAGCCGAATTCTCTGGTGGTTGA GATCCCGCCATTTCGGAATCAGAGGATAACCAGCCCCGTTCACGTCAGTTTCTACGTCTGCAACGGGAAG AGAAAGCGAAGCCAGTACCAGCGTTTCACCTACCTTCCCGCCAACGTTCCAATTATAAAAACAGAACCCA CTGATGATTATGAGCCTGCTCCAACCTGTGGACCGGTGAGCCAGGGGTTAAGTCCTCTCCCAAGACCATA CTACAGCCAGCAGCTCGCGATGCCACCCGACCCCAGCTCCTGCCTCGTGGCCGGCTTCCCGCCCTGTCCG CAGAGAAGCACCCTGATGCCAGCGGCCCCTGGCGTGAGCCCCAAGCTCCACGACCTTTCTCCCGCTGCCT ACACCAAGGGCGTTGCCAGCCCGGGCCACTGTCACCTCGGACTCCCGCAGCCGGCCGGAGAGGCCCCCGC CGTCCAGGACGTGCCCAGGCCAGTGGCCACGCACCCCGGCTCGCCCGGGCAGCCACCCCCGGCCCTGCTG CCACAGCAGTAA >OriGene 5' read for NM_172388 unedited
NGTTTCGGCATTTTNGTATACGATCTCACTATAGGGCGGCCGCGATTCGGCACGAGGAAC CGAACCCCTGGCGGCCGCGACCCCGGCTCCCGCCCCGGCCCCGGCCCCGGCCCGACCCGC CATGACGGGGCTGGAGGACCAGGAGTTCGACTTCGAGTTCCTCTTCGAGTTTAACCAGCG CGACGAGGGCGCCGCCGCGGCCGCCCCAGCCCGACCCTGCCCGCCCTGGACTGGCAGCTG CCGTCCCACTCAGGCCCGTATGAGCTTCGGATTGAGGTGCAGCCCAAGTCCCACCACCGA GCCCACTACGAGACGGAGGGCAGCCGGGGGGCCGTGAAGGCGTCGGCCGGAGGACACCCC ATCGTGCAGCTGCATGGCTACTTGGAGAATGAGCCGCTGATGCTGCAGCTTTTCATTGGG ACGGCGGACGACCGCCTGCTGCGCCCGCACGCCTTCTACCAGGTGCACCGCATCACAGGG AAGACCGTGTCCACCACCAGCCACGAGGCCATCCTCTCCAACACCAAAGTCCTGGAGATC CCACTCCTGCCGGAGAACAGCATGCGAGCCGTCATTGACTGTGCCGGAATCCTGAAACTC AGAAACTCCGACATTGAACTTCGGAAAGGAGAGACGGACATCGGGAGGAAGAACACACGG GTACGGCTGGTGTTCCGCGTTCACGTCCCGCAACCCAGCGGCCGCACGCTGTCCCTGCAG GTGGCCTCCAACCCCATCGAATGCTCCCAGCGCTCAGCTCAGGAGCTGCCTCTGGTGGAG AAGCAGAGCACGGACAGCTATCCGTTCGTGGGCGGNAAGAAGATGGCCCTGTCCGGCCAC ACTTTCTGCAGGACTCCAAGGTCATTTNCGTGGAGAAAGCCCAGATGGCCACCTGTCTGG AAGATGGAGCGAAACTGACCGGGCCTGTGCAAGCGCATTTCTGTGG >OriGene 3' read for NM_172388 unedited
GTACCGCGCCGCAATCTAGTAGTCGAGNNNTTTTTTTTTTTTTTTTTTTTTTACAGCAAA AAAAACGGCTTTATTGGATCTATTTCCTAACTACAAAGACAGCTGACACAGACATCAAAC GTTTCCTTTTCAATGACAGTCCCCTGAAAAAGGCTGCACGTGACTCCTACAGTGCCGGGT GCAGGGTACCCAGCCGCAGGGGGGACGCGGCCACACGTCTTCACGGTTACGTGCAGACCG ACGGGATGGCCTTCAGGTTGTTTCTTTCCGTGAGTGAAACACAAGAGACGCGATTGTGCC GGAGCGCACGGTACAGGCCGTTCCTTCTGCGGGAGCCCTTTTTCCATCAGCGACGTTCTG TTCAGGGACTTCACAGCCGAAGCCTCCACCCGCAGGGGCATTTTAGGCAGGTCCCATAGA GGGGCTTTATTTTCTAAGGCCCTAGTCCAGGCCCCCCCGGCTTCAATGAATAACACCTGC CTCCCGCGCTTCCGGACCACTAGATCGTTGGGAGTATTCTTGCCTGCTAACCCCCTCTTT GGCCTTAGTGCCCCCCATCGCCTCTACACCTCTACCGGAGCCTTGTCCCCTTCGCACCAC ACCCTCCCCCGTCCCCTCACCAATCCCGCGTCACCGGAATTCCCTACCCAATTCACCCCG TTCTGTCTTCTGGTCCCTCCAACCTGAGTCCCCCTGCCTCCTTCCTTTATCATGCTCCAC AAGTTCGGACCCCCTCGGTCTCCCCGATGCCTTCATTATTGTTATATTTCTCATGTTTAG TTCTCGCAACCTCCCGACCTCCAGCTACCGAGCTTCATGAGTTTCGCCTGTTACAGGGCA ACTACATCCCTACGCACCCCTCACCGCTCTATTGCCCACCCGCCGTTTTTCCTCGCCCAT TCGTCCTTCCCACCCGCTCCTATTATGTGCCCTACTCCCGCGCACCGGAGCTGGGTCCAC CGAGTATATGGCATCTCTTACTGACCATATCATTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_172388 |
| Insert Size | 3250 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_172388.1, NP_765976.1 |
| RefSeq Size | 3671 bp |
| RefSeq ORF | 1062 bp |
| Locus ID | 4772 |
| UniProt ID | O95644 |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Axon guidance, B cell receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway |
| Gene Summary | The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. [provided by RefSeq, Jul 2013] Transcript Variant: This variant (4) lacks an internal exon in the 5' region, which results in a downstream translation start codon, and has an alternate splice site in the 3' coding region, compared to variant 6. The encoded isoform (D) is shorter at both the N- and C- termini, compared to isoform F. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Phospho-sulindac inhibits pancreatic cancer growth: NFATc1 as a drug resistance candidate
,Murray, OT;Wong, CC;Vrankova, K;Rigas, B;,
Int. J. Oncol.
,PubMed ID 24284479
[NFATC1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222417 | NFATC1 (Myc-DDK-tagged)-Human nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (NFATC1), transcript variant 4 |
CNY 3,656.00 |
|
| RC222417L1 | Lenti ORF clone of Human nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (NFATC1), transcript variant 4, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC222417L2 | Lenti ORF clone of Human nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (NFATC1), transcript variant 4, mGFP tagged |
CNY 5,890.00 |
|
| RC222417L3 | Lenti ORF clone of Human nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (NFATC1), transcript variant 4, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC222417L4 | Lenti ORF clone of Human nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (NFATC1), transcript variant 4, mGFP tagged |
CNY 5,890.00 |
|
| RG222417 | NFATC1 (tGFP-tagged) - Human nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (NFATC1), transcript variant 4 |
CNY 5,256.00 |
