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EYA4 (NM_172103) Human Untagged Clone
CAT＃: SC109201
EYA4 (untagged)-Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 2
CNY 12,608.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CMD1J; DFNA10 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_172103, the custom clone sequence may differ by one or more nucleotides
ATGGAAGACTCCCAGGATTTAAATGAACAATCAGTAAAGAAAACGTGCACAGAATCAGATGTTTCACAAT CTCAGAATTCCAGGTCTATGGAAATGCAGGACCTAGCAAGTCCTCATACTCTTGTTGGAGGTGGTGATAC TCCAGGTAGCTCCAAACTGGAAAAATCTAATCTCAGCAGCACATCAGTTACTACAAATGGGACAGGAGTG TCTCTTCTTGCAGTCAAAACAGAGCCCTTGAACAGCAGTGAAACCACAGCCACGACTGGAGATGGAGCGC TTGACACTTTTACTGGGTCAGTAATTACAAGTAGTGGCTACAGCCCCAGATCAGCACATCAGTATTCCCC ACAGCTGTATCCTTCCAAGCCCTATCCACACATTCTTTCTACACCAGCAGCTCAAACAATGTCTGCCTAT GCAGGCCAGACTCAGTATTCGGGGATGCAGCAGCCAGCCGTCTACACAGCCTACTCACAGACAGGACAGC CCTACAGCTTGCCCACTTACGATTTGGGTGTGATGTTGCCAGCCATCAAGACAGAGAGTGGACTTTCCCA AACTCAGTCCCCATTACAGAGTGGCTGCCTCAGTTACAGCCCAGGGTTCTCTACCCCACAGCCAGGCCAG ACACCTTATTCTTACCAAATGCCAGGTTCTAGTTTTGCACCATCATCTACTATTTATGCAAATAATTCAG TTTCCAATTCAACGAATTTCAGTGGTTCACAACAGGATTATCCATCCTATACAGCCTTTGGCCAAAACCA GTATGCACAGTATTATTCAGCATCAACGTATGGAGCGTATATGACATCGAATAACACAGCCGATGGCACA CCCTCTTCAACCTCTACTTATCAGTTGCAGGAATCTCTCCCAGGACTGACTAACCAACCAGGAGAGTTCG ATACCATGCAGAGTCCCTCCACACCCATCAAAGATCTTGATGAGAGAACCTGTAGGAGTTCTGGGTCAAA GTCCAGAGGAAGAGGCCGGAAAAATAATCCCTCCCCGCCTCCTGATAGTGACCTGGAGCGTGTGTTTGTC TGGGATTTGGATGAAACCATCATTGTTTTTCACTCACTGCTCACCGGGTCTTATGCACAGAAGTATGGCA AGGATCCCCCCATGGCTGTAACCCTTGGACTCCGCATGGAAGAAATGATTTTTAATCTTGCTGATACTCA TTTGTTTTTTAATGATTTAGAGGAGTGTGATCAAGTTCATATAGATGATGTTTCCTCTGATGATAATGGG CAGGACTTAAGTACCTACAGTTTTGCAACTGATGGCTTCCATGCAGCTGCAAGTAGTGCAAACCTTTGTT TGCCAACAGGTGTAAGAGGAGGGGTTGACTGGATGAGGAAGTTGGCTTTTCGTTACAGAAGAGTAAAAGA ATTATATAACACCTACAAGAACAACGTTGGAGGACTCCTTGGCCCTGCCAAGAGGGATGCCTGGCTACAG TTAAGGGCAGAGATTGAAGGTCTGACAGATTCCTGGCTAACAAATGCACTTAAGTCTTTATCAATTATTA GCACTAGGAGTAACTGCATAAATGTCTTGGTAACGACAACTCAACTGATCCCAGCACTTGCGAAGGTTCT ACTCTATAGTTTAGGAGGTGCTTTCCCCATTGAGAATATTTACAGTGCAACTAAAATAGGAAAAGAAAGT TGCTTTGAACGAATAATGCAAAGGTTTGGCAGAAAAGTAGTGTATGTTGTAATTGGGGATGGTGTAGAAG AAGAACAGGCAGCAAAAAAGCACAACATGCCCTTCTGGAGGATATCCAGTCACTCAGACCTCCTGGCTCT CCACCAAGCACTGGAATTAGAGTATTTGTAA >OriGene 5' read for NM_172103 unedited
CGGATTTTGTATACGATCTCACTATAGGGCGGCCGCGATTCGGCACGAGGGTGGCCGAAG GGATGTCCTGTTTTCACCAGAGGCACAGCGCGAAGGGGAAACTTCGACACTGGAAGGAAC GAGAATAAATACTTAATTACGGACGCACTGAACCGCGGCTGGGACAGACACTTCGGGAAC CCGAGGCGGACCGGGCGACGAGATAGTCATTTTTACTTGAAGGAAGCTGCTTCTACTTGG GAGTGGCAGGAGAAGTGAGAAAACCACATGGAAGACTCCCAGGATTTAAATGAACAATCA GTAAAGAAAACGTGCACAGAATCAGATGTTTCACAATCTCAGAATTCCAGGTCTATGGAA ATGCAGGACCTAGCAAGTCCTCATACTCTTGTTGGAGGTGGTGATACTCCAGGTAGCTCC AAACTGGAAAAATCTAATCTCAGCAGCACATCAGTTACTACAAATGGGACAGGAGTGTCT CTTCTTGCAGTCAAAACAGAGCCCTTGAACAGCAGTGAAACCACAGCCACGACTGGAGAT GGAGCGCTTGACACTCTTACTGGGTCAGTAATTACAAGTAGTGGCTACAGCCCCAGATCA GCACATCAGTATTCCCCACAGCTGTATCCTTCCAAGCCCTATCCACACATTCTTTCTACA CCAGCAGCTCAAACAATGTCTGCCTATGCAGGCCAGACTCAGTATTCGGGGATGCAGCAG CCAGCCGTCTACACAGCCTACTCACAGACAGGACAGNCCTACAGCTTGGCCACTTACGAT TTGGGGTGTGATGTTGCCAGCCATCCAGACAGAGAGTGGACTTTCCAAACTCAATCCCCA TTACAGAGTGGGCTGCTCAGTTACAGCCCAGGGTTTTCTACCCNAAGNCAGCCAGGAAAC TTAATCTTACCAAATGCAGGTTCTAGTTTGACCATATT >OriGene 3' genomic read for NM_172103 unedited
CCCCCAAATGTTAGNCCGCGGCCGCAATCTACGAGCGGGTNTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTAAGAGCCGACCTGGATTTTAAGGGGAATAATA GCCAATATTAACATTTTTTAGATAGTTTAAAATTTATTTTGGAAGTATCGTTACCAACAT CAACATTTGGGAAAGCAAGGGGGCATCAAAATCCTACCTGGTTAAGGGAAAGCAGGTTTT AATCAGGGCATCACTCCTACGGGCCTTTCAATTAAAAATAAAATGAAACCAAATGACCAA CTTTTTAATTTTGTTAATCTAGGAAGAAAAGAGGGTGAATTCCTTTTTGTATAAAAATAA TTTGAAGCCGGACTACCTAAAGTAAAAAAAAAAGGGGGGGATTATAACTTTTTTACTTGT TTGGGACCACCCATAACTTAAGCCCGTAGAGGCCACCTGATTTATTTCACTGGCGTAAAA TTGAGAGAAAGTACTTTAGCATACATTTTCAAGGGGGAAGATATTTCCCAAGGGACCCAA ATGAGCTTTTGTGGGGCAAAAAAACTTAGACAATACCGGGGTGTTGGGGCCTTCAAAAGA GATACTATAATAGTATACCGTCCATATGTGACATTAAAATTTCATGAAAGGGGGTAATTA GAGAAAAACTGGTAAAGGAGTCCCACTGGCGATGATAATGAAAAGAAAAAACCCTGCTTA CANGAACTGGCCAAACAAAGCATGAATTGNTAAATTTGGGCTGGGGACATTTTTAGAAAA TTTCCTATAACAATTCTGTTTTAGGGAAAGGGGTTTTTGAATTAAACATGCACAGAATTT TTTTAAGAGCTAGGCCAAAGACCCTTTTGTTATTATTCTTTTTCCACATAGGACCACCCC CCTGGGGATTGGCATTAAAGGGTTGGACCTTTAAAACAAGGATTCAGACTTGCCAAC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_172103 |
| Insert Size | 4400 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_172103.1, NP_742101.1 |
| RefSeq Size | 5628 bp |
| RefSeq ORF | 5628 bp |
| Locus ID | 2070 |
| UniProt ID | O95677 |
| Protein Families | Druggable Genome, Phosphatase, Transcription Factors |
| Gene Summary | This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye development, and for continued function of the mature organ of Corti. Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss at the deafness, autosomal dominant non-syndromic sensorineural 10 locus. The encoded protein is also a putative oncogene that mediates DNA repair, apoptosis, and innate immunity following DNA damage, cellular damage, and viral attack. Defects in this gene are also associated with dilated cardiomyopathy 1J. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014] Transcript Variant: This variant (2) lacks an in-frame segment of the 5' coding region, compared to variant 1. The resulting isoform (b) is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208336 | EYA4 (Myc-DDK-tagged)-Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 2 |
CNY 4,584.00 |
|
| RC208336L1 | Lenti ORF clone of Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 2, Myc-DDK-tagged |
CNY 6,984.00 |
|
| RC208336L2 | Lenti ORF clone of Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 2, mGFP tagged |
CNY 6,984.00 |
|
| RC208336L3 | Lenti ORF clone of Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC208336L4 | Lenti ORF clone of Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG208336 | EYA4 (tGFP-tagged) - Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 2 |
CNY 6,184.00 |
|
| SC318057 | EYA4 (untagged)-Human eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 2 |
CNY 7,220.00 |
