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BMPR2 (NM_001204) Human Untagged Clone
CAT＃: SC108987
BMPR2 (untagged)-Human bone morphogenetic protein receptor, type II (serine/threonine kinase) (BMPR2)
CNY 10,848.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BMPR-II; BMPR3; BMR2; BRK-3; POVD1; PPH1; T-ALK |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_001204 edited
ATGACTTCCTCGCTGCAGCGGCCCTGGCGGGTGCCCTGGCTACCATGGACCATCCTGCTG GTCAGCGCTGCGGCTGCTTCGCAGAATCAAGAACGGCTATGTGCGTTTAAAGATCCGTAT CAGCAAGACCTTGGGATAGGTGAGAGTAGAATCTCTCATGAAAATGGGACAATATTATGC TCGAAAGGTAGCACCTGCTATGGCCTTTGGGAGAAATCAAAAGGGGACATAAATCTTGTA AAACAAGGATGTTGGTCTCACATTGGAGATCCCCAAGAGTGTCACTATGAAGAATGTGTA GTAACTACCACTCCTCCCTCAATTCAGAATGGAACATACCGTTTCTGCTGTTGTAGCACA GATTTATGTAATGTCAACTTTACTGAGAATTTTCCACCTCCTGACACAACACCACTCAGT CCACCTCATTCATTTAACCGAGATGAGACAATAATCATTGCTTTGGCATCAGTCTCTGTA TTAGCTGTTTTGATAGTTGCCTTATGCTTTGGATACAGAATGTTGACAGGAGACCGTAAA CAAGGTCTTCACAGTATGAACATGATGGAGGCAGCAGCATCCGAACCCTCTCTTGATCTA GATAATCTGAAACTGTTGGAGCTGATTGGCCGAGGTCGATATGGAGCAGTATATAAAGGC TCCTTGGATGAGCGTCCAGTTGCTGTAAAAGTGTTTTCCTTTGCAAACCGTCAGAATTTT ATCAACGAAAAGAACATTTACAGAGTGCCTTTGATGGAACATGACAACATTGCCCGCTTT ATAGTTGGAGATGAGAGAGTCACTGCAGATGGACGCATGGAATATTTGCTTGTGATGGAG TACTATCCCAATGGATCTTTATGCAAGTATTTAAGTCTCCACACAAGTGACTGGGTAAGC TCTTGCCGTCTTGCTCATTCTGTTACTAGAGGACTGGCTTATCTTCACACAGAATTACCA CGAGGAGATCATTATAAACCTGCAATTTCCCATCGAGATTTAAACAGCAGAAATGTCCTA GTGAAAAATGATGGAACCTGTGTTATTAGTGACTTTGGACTGTCCATGAGGCTGACTGGA AATAGACTGGTGCGCCCAGGGGAGGAAGATAATGCAGCCATAAGCGAGGTTGGCACTATC AGATATATGGCACCAGAAGTGCTAGAAGGAGCTGTGAACTTGAGGGACTGTGAATCAGCT TTGAAACAAGTAGACATGTATGCTCTTGGACTAATCTATTGGGAGATATTTATGAGATGT ACAGACCTCTTCCCAGGGGAATCCGTACCAGAGTACCAGATGGCTTTTCAGACAGAGGTT GGAAACCATCCCACTTTTGAGGATATGCAGGTTCTCGTGTCTAGGGAAAAACAGAGACCC AAGTTCCCAGAAGCCTGGAAAGAAAATAGCCTGGCAGTGAGGTCACTCAAGGAGACAATC GAAGACTGTTGGGACCAGGATGCAGAGGCTCGGCTTACTGCACAGTGTGCTGAGGAAAGG ATGGCTGAACTTATGATGATTTGGGAAAGAAACAAATCTGTGAGCCCAACAGTCAATCCA ATGTCTACTGCTATGCAGAATGAACGCAACCTGTCACATAATAGGCGTGTGCCAAAAATT GGTCCTTATCCAGATTATTCTTCCTCCTCATACATTGAAGACTCTATCCATCATACTGAC AGCATCGTGAAGAATATTTCCTCTGAGCATTCTATGTCCAGCACACCTTTGACTATAGGG GAAAAAAACCGAAATTCAATTAACTATGAACGACAGCAAGCACAAGCTCGAATCCCCAGC CCTGAAACAAGTGTCACCAGCCTCTCCACCAACACAACAACCACAAACACCACAGGACTC ACGCCAAGTACTGGCATGACTACTATATCTGAGATGCCATACCCAGATGAAACAAATCTG CATACCACAAATGTTGCACAGTCAATTGGGCCAACCCCTGTCTGCTTACAGCTGACAGAA GAAGACTTGGAAACCAACAAGCTAGACCCAAAAGAAGTTGATAAGAACCTCAAGGAAAGC TCTGATGAGAATCTCATGGAGCACTCTCTTAAACAGTTCAGTGGCCCAGACCCACTGAGC AGTACTAGTTCTAGCTTGCTTTACCCACTCATAAAACTTGCAGTAGAAGCAACTGGACAG CAGGACTTCACACAGACTGCAAATGGCCAAGCATGTTTGATTCCTGATGTTCTGCCTACT CAGATCTATCCTCTCCCCAAGCAGCAGAACCTTCCCAAGAGACCTACTAGTTTGCCTTTG AACACCAAAAATTCAACAAAAGAGCCCCGGCTAAAATTTGGCAGCAAGCACAAATCAAAC TTGAAACAAGTCGAAACTGGAGTTGCCAAGATGAATACAATCAATGCAGCAGAACCTCAT GTGGTGACAGTCACCATGAATGGTGTGGCAGGTAGAAACCACAGTGTTAACTCCCATGCT GCCACAACCCAATATGCCAATGGGACAGTACTATCTGGCCAAACAACCAACATAGTGACA CATAGGGCCCAAGAAATGTTGCAGAATCAGTTTATTGGTGAGGACACCCGGCTGAATATT AATTCCAGTCCTGATGAGCATGAGCCTTTACTGAGACGAGAGCAACAAGCTGGCCATGAT GAAGGTGTTCTGGATCGTCTTGTGGACAGGAGGGAACGGCCACTAGAAGGTGGCCGAACT AATTCCAATAACAACAACAGCAATCCATGTTCAGAACAAGATGTTCTTGCACAGGGTGTT CCAAGCACAGCAGCAGATCCTGGGCCATCAAAGCCCAGAAGAGCACAGAGGCCTAATTCT CTGGATCTTTCAGCCACAAATGTCCTGGATGGCAGCAGTATACAGATAGGTGAGTCAACA CAAGATGGCAAATCAGGATCAGGTGAAAAGATCAAGAAACGTGTGAAAACTCCCTATTCT CTTAAGCGGTGGCGCCCCTCCACCTGGGTCATCTCCACTGAATCGCTGGACTGTGAAGTC AACAATAATGGCAGTAACAGGGCAGTTCATTCCAAATCCAGCACTGCTGTTTACCTTGCA GAAGGAGGCACTGCTACAACCATGGTGTCTAAAGATATAGGAATGAACTGTCTGTGA >OriGene 5' read for NM_001204 unedited
CCAATTCCCTCGAGGGTGAAGGAAGTCCCGAAGCGAAACTTAAGGAATCCTGCCTTCCCG GAGCCGCGGGCGATGCGACTAGGGCTGCCGGGCGCCGCCGCCGCCCGTCCGGCTTCGTCC TTCCCGGCAGTCGGGAACTAGTTCTGACCCTCGCCCCCCGACCCCGGATCGATANCCTTG CTCTCCGCACCCTGGATATGTTTTCTCCCAGACCTGGATATTTTTTTGATATCGTGAAAC TACGAGGGAAATAATTTGGGGGATTTCTTCTTGGCTCCCTGCTTTCCCCACAGACATGCC TTCCGTTTGGAGGGCCGCGGCACCCCGTCCGAGGCGAAGGAACCCCCCCAGCCGCGAGGG AGAGAAATGAAGGGAATTTCTGCAGCGGCATGAAAGCTCTGCAGCTAGGTCCTCTCATCA GCCATTTGTCCTTTCAAACTGTATTGTGATACGGGCAGGATCAGTCCACGGGAGAGAAGA CGAGCCTCCCGGCTGTTTCTCCGCCGGTCTACTTCCCATATTTCTTTTCTTTGCCCTCCT GATTCTTGGCTGGCCCAGGGATGACTTCCTCGCTGCAGCGGCCCTGGCGGGTGCCCTGGC TACCATGGACCATCCTGCTGGTCAGCGCTGCGGCTGCTTCGCAGAATCAAGAACGGCTAT GTGCGTTTAAAGATCCGTATCAGCAAGACCCTTGGATAGGTGAGAGTAGAATCTCTCATN GAAATGGGACAATATTATGCTCGAAAGGTAGCACCTGCTATGGGCCTTGGGAGAAATCAA AAGGGACATAAATCTTGTAAACAGGGATGTTGGTCTCACATTTGGAGATCCCAAGAGTGT CCCTTTGAAAATGTGTAGTAACTACCCT >OriGene 3' read for NM_001204 unedited
NTCCCCCCCCCCGGTCCNCCGCCGCCCCCCTCCCCCNCCNNTCCTCCGCCTCTGCTCCGC GGCCCGGCATCTAGCATCGAGTTTTTTTTTTTTTTTTTTAAACATCTTCTGCATGTTTAA ATGATGCAAAAAAAATTTCACTCCATAGGCTTGAAAACATTTCACAGACAGTTCATTCCT ATATCTTTAGACACCATGGTTGTAGCAGTGCCTCCTTCTGCAAGGTAAACAGCAGCGCTG GATTTGGAATGAACTGCCCTGTTACTGCCATTATTGTTGACTTCACAGTCCAGCGATTCA GTGGAGATGACCCAGGTGGAGGGGCGCCACCGCTTAAGAGAATAGGGAGTTTTCACACGT TTCTTGATCTTTTCACCTGATCCTGATTTGCCATCTTGTGTTGACTCACCTATCTGTATA CTGCTGCCATCCAGGACATTTGTGGCTGAAAGATCCAGAGAATTAGGCCTCTGTGCTCTT CTGGGCTTTGATGGCCCAGGATCTGCTGCTGTGCTTGGAACACCCTGTGCAAGAACATCT TGCCCTGAACATGGATTGCTGTTGTTGTTATTGGAATTAGTTCGGCCACCTTCTAGTTGG CCGCTCCCTCCTGTCCACAAGACGATCCAGAACACCTTCATCATGGCCAGNTTGNTGCTC TCGTCTCAGTAAAGGCTCATGCTCATCAGGACTGTGATTCATACTCACCCCGTGTGTCCT TACCAATAAACTGATTCTCGAACATTTCTTGGCCCTTATGTGTCACTATGTTCGGTGCTT GGCCAGACACTACCGGCCCATTGCACATTGGGTTCGGGCCCATGGCACTTACCACTGTGG CTTCTACCTGCCACACCATCCTGGGGACTGCCACACAAGAGGCTTTGTGCATTGATTGGT TTTATTTGGGCACCTCAGTTCCACTTGTTTAAGGTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001204 |
| Insert Size | 3670 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001204.5, NP_001195.2 |
| RefSeq Size | 11449 bp |
| RefSeq ORF | 3117 bp |
| Locus ID | 659 |
| UniProt ID | Q13873 |
| Domains | Activin_recp, pkinase, TyrKc, S_TKc |
| Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway |
| Gene Summary | This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, May 2020] Transcript Variant: This variant (1) encodes the full length isoform. Isoform 1 is 508 aa longer than isoform 2 and includes a long cytoplasmic tail unique to this bone morphogenetic protein type II receptor. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Synthesis and Conformational Evaluation of a Novel Gene Delivery Vector for Human Mesenchymal Stem Cells
,Anita Saraf, Michael C. Hacker, Balaji Sitharaman, K. Jane Grande-Allen, Michael A. Barry and Antonios G. Mikos,
Biomacromolecules, 2008, 9 (3), pp 818–827
[BMPR2]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208673 | BMPR2 (Myc-DDK-tagged)-Human bone morphogenetic protein receptor, type II (serine/threonine kinase) (BMPR2) |
CNY 10,840.00 |
|
| RC208673L1 | Lenti ORF clone of Human bone morphogenetic protein receptor, type II (serine/threonine kinase) (BMPR2), Myc-DDK-tagged |
CNY 13,240.00 |
|
| RC208673L2 | Lenti ORF clone of Human bone morphogenetic protein receptor, type II (serine/threonine kinase) (BMPR2), mGFP tagged |
CNY 13,240.00 |
|
| RC208673L3 | Lenti ORF clone of Human bone morphogenetic protein receptor, type II (serine/threonine kinase) (BMPR2), Myc-DDK-tagged |
CNY 13,240.00 |
|
| RC208673L4 | Lenti ORF clone of Human bone morphogenetic protein receptor, type II (serine/threonine kinase) (BMPR2), mGFP tagged |
CNY 13,240.00 |
|
| RG208673 | BMPR2 (tGFP-tagged) - Human bone morphogenetic protein receptor, type II (serine/threonine kinase) (BMPR2) |
CNY 12,440.00 |
