GPR172A (SLC52A2) (NM_024531) Human Untagged Clone
CAT#: SC108833
SLC52A2 (untagged)-Human G protein-coupled receptor 172A (GPR172A)
CNY 3,656.00
Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 3,280.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | BVVLS2; D15Ertd747e; GPCR41; GPR172A; hRFT3; PAR1; RFT3; RFVT2 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC108833 sequence for NM_024531 edited (data generated by NextGen Sequencing)
ATGGCAGCACCCACGCCCGCCCGTCCGGTGCTGACCCACCTGCTGGTGGCTCTCTTCGGC ATGGGCTCCTGGGCTGCGGTCAATGGGATCTGGGTGGAGCTACCTGTGGTGGTCAAAGAG CTTCCAGAGGGTTGGAGCCTCCCCTCTTACGTCTCTGTGCTTGTGGCTCTGGGGAACCTG GGTCTGCTGGTGGTGACCCTCTGGAGGAGGCTGGCCCCAGGAAAGGACGAGCAGGTCCCC ATCCGGGTGGTGCAGGTGCTGGGCATGGTGGGCACAGCCCTGCTGGCCTCTCTGTGGCAC CATGTGGCCCCAGTGGCAGGACAGTTGCATTCTGTGGCCTTCTTAGCACTGGCCTTTGTG CTGGCACTGGCATGCTGTGCCTCGAATGTCACTTTCCTGCCCTTCTTGAGCCACCTGCCA CCTCGCTTCTTACGGTCATTCTTCCTGGGTCAAGGCCTGAGTGCCCTGCTGCCCTGCGTG CTGGCCCTAGTGCAGGGTGTGGGCCGCCTCGAGTGCCCGCCAGCCCCCATCAACGGCACC CCTGGCCCCCCGCTCGACTTCCTTGAGCGTTTTCCCGCCAGCACCTTCTTCTGGGCACTG ACTGCCCTTCTGGTCGCTTCAGCTGCTGCCTTCCAGGGTCTTCTGCTGCTGTTGCCGCCA CCACCATCTGTACCCACAGGGGAGTTAGGATCAGGCCTCCAGGTGGGAGCCCCAGGAGCA GAGGAAGAGGTGGAAGAGTCCTCACCACTGCAAGAGCCACCAAGCCAGGCAGCAGGCACC ACCCCTGGTCCAGACCCTAAGGCCTATCAGCTTCTATCAGCCCGCAGTGCCTGCCTGCTG GGCCTGTTGGCCGCCACCAACGCGCTGACCAATGGCGTGCTGCCTGCCGTGCAGAGCTTT TCCTGCTTACCCTACGGGCGTCTGGCCTACCACCTGGCTGTGGTGCTGGGCAGTGCTGCC AATCCCCTGGCCTGCTTCCTGGCCATGGGTGTGCTGTGCAGGTCCTTGGCAGGGCTGGGC GGCCTCTCTCTGCTGGGCGTGTTCTGTGGGGGCTACCTGATGGCGCTGGCAGTCCTGAGC CCCTGCCCGCCCCTGGTGGGCACCTCGGCGGGGGTGGTCCTCGTGGTGCTGTCGTGGGTG CTGTGTCTTGGCGTGTTCTCCTACGTGAAGGTGGCAGCCAGCTCCCTGCTGCATGGCGGG GGCCGGCCGGCATTGCTGGCAGCCGGCGTGGCCATCCAGGTGGGCTCTCTGCTCGGCGCT GTTGCTATGTTCCCCCCGACCAGCATCTATCACGTGTTCCACAGCAGAAAGGACTGTGCA GACCCCTGTGACTCCTGA Clone variation with respect to NM_024531.3 >OriGene 5' read for NM_024531 unedited
GTGTTAGNATTTATGTATACGACTCACTATAGGGCGGCCGGCGAATCGGCACGAGGGTCC CTGGGCCGGACGGCGGTGTCCCGGCGTGGCGGGAAGCCGGCACTGGAGCGGGAGCGCACT GGGCGCGGGACCGGGAGGCGCAGGGACCGGACGGCTCCCGAGTCGCCCACCTGACGGTAC CGAGAGGGCGGCGCCCCTCCGAGCAGAGCCGTCCCGGCCACTCCCCTGGGATCTGACTTG GCTCTTGCGGTCGCGGGCACCGTGAAGCCCTGGGGTGTGCGTGGCTCCTCCTGGTAGGCG CCCTTTCCCGGCGTCCGGCTTGGGGTGGTGGTGGCGTTGACTCCAGCCCCGCCTCTCCCT GGAGAGGAGGGCTCCACTCGCTCCTTCGGCCTCCTCCCCTGGGGCCGCAGCGACTCGGGC CGGCTTCCTGCTTCCCTGCCTGCCGGCGGTCCCGCTGGCTAGAAGAAGTCTTCACTTCCC AGGAGAGCCAAAGCGTGTCTGGCCCTAGGTGGGAAAAGAACTGGCTGTGACCTTTGCCCT GACCTGGAAGGGCCCAGCCTTGGGCTGAATGGCAGCACCCACGCCCGCCCGTCCGGTGCT GACCCACCTGCTGGTGGCTCTCTTCGGCATGGGCTCCTGTGCTGCGGTCAATGGGATCTG GGTGGAGCTACCTGTGGTGGTCAAAGAGCTTCCAGAGGGTTGGAGCCTCCCCTCTTACGT CTCTGTGCTTGTGGCTCTGGGGAACCTGCGTCTGCTTGTGGTGACCCTCTGGAGGTAGCT TGCCCCCAGGAAAGGACGAGCAGGTCCCCATCCGGGTGGTGCAGGTGCCTGGCCATGTTG GGCACACGCCTTGCTGGCCCTCTTTGTGGCACCATGTGGCGCCAGTGGCAGGACAGTTGC ATTCTGTGGCCTTTTTAAACTGGGCTTTG >OriGene 3' read for NM_024531 unedited
TTATGGACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTAAATACAAAT GTTTTATTACGCAAACCACATGTAGGTCCCAGGCTCAGGGGCTTACCCTACAGCCCCCAC TGGTCCCTGGCTCCAAGCCTGCTCCTTGCCCTTGCCCACCCTGGAAAGCCAGGATCTCCT ATGGAGTGTGTAGGTGTCCACGAGTGTACCGGTGTGCGGGCCTCCTGGGCTGCAGGCACT CAGGCATGGTGGCAGCATTGAGGGAAAGACAGGTGTTGGGGAGCGGGGTCCCCACCTGCC CAGGCTCAGGAGTCACAGGGGTCTGCACAGTCCTTTCTGCTGTGGAACACGTGATAGATG CTGGTCGGGGGGAACATAGCAACAGCGCCGAGCAGAGAGCCCACCTGGATGGCCACGCCG GCTGCCAGCAATGCCGGCCGGCCCCCGCCATGCAGCAGGGAGCTGGCTGCCACCTTCACG TAGGAGAACACGCCAAGACACAGCACCCACGACAGCACCACGAGGACCACCCNCGCCGAG GTGCCCACCAGGGGCGGGCAGGGGCTCANGACTGCCAGCGCCATCAGGTAGCCCCCACAG AACACGCCCAGCAGAGAGAGGGCCGCCAGCCCTGCCAAGGACCTGCACAGCACACCCATG GCCAGGAAGCAGGCCCAGGGGATTGGCAGCACTGGCCAGCACCACAGCCAGGTGGTAGGC CANACGCCCGTAGGTTAAGCAGGAAAAGCTCTGCACGGGAAGCAACACGCCATTGGTCAG CGCGGTGGTGGCGGCCCACAGGCCCAACAAGCAGGGCCTGCGGGCTGATAAAAACTGATA GGCCCTAAGGGCTGGACCAAGGGGGGGGCCTGCTGCCCTGCTGGGGGGTCTTGCATGGTG AAGACTTTTCCACCTTTTCTTTGTTCTGGGGCTCCACCTGAAGGCTGATCCAT |
Restriction Sites | NotI-NotI |
ACCN | NM_024531 |
Insert Size | 2170 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_024531.3, NP_078807.1 |
RefSeq Size | 1952 bp |
RefSeq ORF | 1338 bp |
Locus ID | 79581 |
UniProt ID | Q9HAB3 |
Protein Families | Druggable Genome, GPCR, Transmembrane |
Gene Summary | This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia. [provided by RefSeq, Jul 2012] Transcript Variant: This variant (1) encodes isoform 1. Variants 1, 2, 3, 5, 6 and 7 encode the same isoform (1). |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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In Vitro Effects of Paclitaxel and Cremophor EL on Human Riboflavin Transporter SLC52A2
,Hino, H;Yang, M;Dalvi, P;Chen, T;Sun, L;Harper, PA;Ito, S;,
Biol. Pharm. Bull.
,PubMed ID 31902922
[SLC52A2]
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