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TXNIP (NM_006472) Human Untagged Clone
CAT＃: SC108573
TXNIP (untagged)-Human thioredoxin interacting protein (TXNIP)
CNY 5,488.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARRDC6; EST01027; HHCPA78; THIF; VDUP1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_006472 edited
GTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGAACCGTCAGAATT TTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCTCGTGCCGAATTC GGCACGAGGCTTTTTCTCCAAAGGAGTGCTTGTGGAGATCGGATCTTTTCTCCAGCAATT GGGGGAAAGAAGGCTTTTTCTCTGAATTCGCTTAGTGTAACCAGCGGCGTATATTTTTTA GGCGCCTTTTCGAAAACCTAGTAGTTAATATTCATTTGTTTAAATCTTATTTTATTTTTA AGCTCAAACTGCTTAAGAATACCTTAATTCCTTAAAGTGAAATAATTTTTTGCAAAGGGG TTTCCTCGATTTGGAGCTTTTTTTTTCTTCCACCGTCATTTCTAACTCTTAAAACCAACT CAGTTCCATCATGGTGATGTTCAAGAAGATCAAGTCTTTTGAGGTGGTCTTTAACGACCC TGAAAAGGTGTACGGCAGTGGCGAGAAGGTGGCTGGCCGGGTGATAGTGGAGGTGTGTGA AGTTACTCGTGTCAAAGCCGTTAGGATCCTGGCTTGCGGAGTGGCTAAAGTGCTTTGGAT GCAGGGATCCCAGCAGTGCAAACAGACTTCGGAGTACCTGCGCTATGAAGACACGCTTCT TCTGGAAGACCAGCCAACAGGTGAGAATGAGATGGTGATCATGAGACCTGGAAACAAATA TGAGTACAAGTTCGGCTTTGAGCTTCCTCAGGGGCCTCTGGGAACATCCTTCAAAGGAAA ATATGGGTGTGTAGACTACTGGGTGAAGGCTTTTCTTGACCGCCCGAGCCAGCCAACTCA AGAGACAAAGAAAAACTTTGAAGTAGTGGATCTGGTGGATGTCAATACCCCTGATTTAAT GGCACCTGTGTCTGCTAAAAAAGAAAAGAAAGTTTCCTGCATGTTCATTCCTGATGGGCG GGTGTCTGTCTCTGCTCGAATTGACAGAAAAGGATTCTGTGAAGGTGATGAGATTTCCAT CCATGCTGACTTTGAGAATACATGTTCCCGAATTGTGGTCCCCAAAGCTGCCATTGTGGC CCGCCACACTTACCTTGCCAATGGCCAGACCAAGGTGCTGACTCAGAAGTTGTCATCAGT CAGAGGCAATCATATTATCTCAGGGACATGCGCATCATGGCGTGGCAAGAGCCTTCGGGT TCAGAAGATCAGGCCTTCTATCCTGGGCTGCAACATCCTTCGAGTTGAATATTCCTTACT GATCTATGTTAGCGTTCCTGGATCCAAGAAGGTCATCCTTGACCTGCCCCTGGTAATTGG CAGCAGATCAGGTCTAAGCAGCAGAACATCCAGCATGGCCAGCCGAACCAGCTCTGAGAT GAGTTGGGTAGATCTGAACATCCCTGATACCCCAGAAGCTCCTCCCTGCTATATGGATGT CATTCCTGAAGATCACCGATTGGAGAGCCCAACCACTCCTCTGCTAGATGACATGGATGG CTCTCAAGACAGCCCTATCTTTATGTATGCCCCTGAGTTCAAGTTCATGCCACCACCGAC TTATACTGAGGTGGATCCCTGCATCCTCAACAACAATGTGCAGTGAGCATGTGGAAGAAA AGAAGCAGCTTTACCTACTTGTTTCTTTTTGTCTCTCTTCCTGGACACTCACTTTTTCAG AGACTCAACAGTCTCTGCAATGGAGTGTGGGTCCACCTTAGCCTCTGACTTCCTAATGTA GGAGGTGGTCAGCAGGCAATCTCCTGGGCCTTAAAGGATGCGGACTCATCCTCAGCCAGC GCCCATGTTGTGATACAGGGGTGTTTGTTGGATGGGTTTAAAAATAACTAGAAAAACTCA GGCCCATCCATTTTCTCAGATCTCCTTGAAAATTGAGGCCTTTTCGATAGTTTCGGGTCA GGTAAAAATGGCCTCCTGGCGTAAGCTTTTCAAGGTTTTTTGGAGGCTTTTTGTAAATTG TGATAGGAACTTTGGACCTTGAACTTACGTATCATGTGGAGAAGAGCCAATTTAACAAAC TAGGAAGATGAAAAGGGAAATTGTGGCCAAAACTTTGGGAAAAGGAGGTTCTTAAAATCA GTGTTTCCCCTTTGTGCACTTGTAGAAAAAAAAGAAAAACCTTCTAGAGCTGATTTGATG GACAATGGAGAGAGCTTTCCCTGTGATTATAAAAAAGGAAGCTAGCTGCTCTACGGTCAT CTTTGCTTAGAGTATACTTTAACCTGGCTTTTAAAGCAGTAGTAACTGCCCCACCAAAGG TCTTAAAAGCCATTTTTGGAGCCTATTGCACTGTGTTCTCCTACTGCAAATATTTTCATA TGGGAGGATGGTTTTCTCTTCATGT >OriGene 5' read for NM_006472 unedited
TACGATATTTGTATACGACTTCACTATAGGGCGGCCGCGAATTCGCACGAGGCCTCGTGC CGAATTCGGCACGAGGCTTTTTCTCCAAGGAGTGCTTGTGGAGATCGGATCTTTTCTCCA GCAATTGGGGGAAAGAAGGCTTTTTCTCTGAATTCGCTTAGTGTAACCAGCGGCGTATAT TTTTTAGGCGCCTTTTCGAAAACCTAGTAGTTAATATTCATTTGTTTAAATCTTATTTTA TTTTTAAGCTCAAACTGCTTAAGAATACCTTAATTCCTTAAAGTGAAATAATTTTTTGCA AAGGGGTTTCCTCGATTTGGAGCTTTTTTTTTCTTCCACCGTCATTTCTAACTCTTAAAA CCAACTCAGTTCCATCATGGTGATGTTCAAGAAGATCAAGTCTTTTGAGGTGGTCTTTAA CGACCCTGAAAAGGTGTACGGCAGTGGCGAGAAGGTGGCTGGCCGGGTGATAGTGGAGGT GTGTGAAGTTACTCGTGTCAAAGCCGTTAGGATCCTGGCTTGCGGAGTGGCTAAAGTGCT TTGGATGCAGGGATCCCAGCAGTGCAAACAGACTTCGGAGTACCTGCGCTATGAAGACAC GCTTCTTCTGGAAGACCAGCCAACAGGTGAGAATGAGATGGTGATCATGAGACCTGGAAA CAATATGAGTACAAGTTCGGCTTTGAGCTTCCTCAGGGGCCTCTGGGAACATCCTTCAAA GAAAATATGGGTGTGTAGACTACTGGGTGAAGGCTTTTCTTGACCGCCCGAGCCAGCCAA CTCAAGAGACAAAGAAAACTTTGAAATACTGGATCTGGTGGGAGGCAATACCCCTGATTA ATGCCACCTGGGTCTGCTAAAAAGAAAAGAAGTTCCTGCATGTTCCTCCTGAAGGGCGGG TGGCTGTCTCTGCTTCAATTGCACCAAAGGAATCTGT >OriGene 3' read for NM_006472 unedited
NGGTTTTTGCTGTGNNAAGACGGCCCGCTTTTCTAAGATCGAGTTTTTTTTTTTTTTTTT TCCATTAAAAAAACTTTATTTTCATTTTTTACAAAAAAACCCCCATCTGGGGTAAAAAAT ATCTGGTTAAGTACAAAATATAGTCTTTACCATACAAAAAGATACATAATACAAAAACAT GAAACCAACCATCTTCAGCCCACACTTTCTGGCTGTAATAACTCTCAGAAAAGGGTGGAG CTCAGTGCTCTGACACAGGACAGTGAACAAAGTGCTATGGCTGAGAGTGACTGACCAAGT GCTGGCAGCTGCAGTGAGGGGCCAATATCCCTATCTCCTAACACAGGGCAGGAAGGGGGT TCAAAGGGCTTTTATGAAGACCTGCCCTCTAGTTTCTCATGGCAGTATTTGGAGGTTCTG ATCACAGGGTTGGGCATTTTGATCAAGAGTCCCTCCTTGGGTTCGAAGCCACAGCGGGCA AGGCTGACAGCAGCAACCCTCTCACATGCTTCAAGTGCTACAACCATATACCTCCGCCCA TCGGGGTAATCTCAAAAGCAGTACAAATCTCTCCCGTCTCTCTGCATTCACCCCTATTCC ACATCAGCCACCCTATTCTCCCGTCTTACATTGTATGATGGTCCCACGGCGGCCCAACAT AACCCCGTGACCAGGCACTTCACAGTGGCTTAACACACATAACCCTTTATACCCTCCCCC CTCAGGACCTCCACCGCACATAGACCACCCTTCCTACCTTAACCGATACAACACTCGCAG CCAGGCAATTCCCAGCGTGAAAAGGGCTCCCACCACCGGCCCTCTACAGCACCTCCCGTG GGGCGGTGATTACTACCTGCCCTTTCTCACCCATCTCCTAACTTTTCCCTTTATCCCCCT TTACCCGTAATGGAAAAAATTACCTTCCTCTCCACCCAGCCCAAACCCCTCTCTCTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_006472 |
| Insert Size | 2260 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006472.1, NP_006463.2 |
| RefSeq Size | 2704 bp |
| RefSeq ORF | 1176 bp |
| Locus ID | 10628 |
| UniProt ID | Q9H3M7 |
| Domains | arrestin |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Anti-Argonaute RIP-Chip shows that miRNA transfections alter global patterns of mRNA recruitment to microribonucleoprotein complexes
,Wang-Xia Wang, Bernard R. Wilfred, Yanling Hu, Arnold J. Stromberg, and Peter T. Nelson,
RNA, Feb 2010; 16: 394 - 404
[TXNIP]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210804 | TXNIP (Myc-DDK-tagged)-Human thioredoxin interacting protein (TXNIP) |
CNY 5,488.00 |
|
| RC210804L1 | Lenti ORF clone of Human thioredoxin interacting protein (TXNIP), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC210804L2 | Lenti ORF clone of Human thioredoxin interacting protein (TXNIP), mGFP tagged |
CNY 5,890.00 |
|
| RC210804L3 | Lenti ORF clone of Human thioredoxin interacting protein (TXNIP), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC210804L4 | Lenti ORF clone of Human thioredoxin interacting protein (TXNIP), mGFP tagged |
CNY 7,888.00 |
|
| RG210804 | TXNIP (tGFP-tagged) - Human thioredoxin interacting protein (TXNIP) |
CNY 7,088.00 |
