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HB EGF (HBEGF) (NM_001945) Human Untagged Clone
CAT＃: SC108485
HBEGF (untagged)-Human heparin-binding EGF-like growth factor (HBEGF)
CNY 2,400.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DTR; DTS; DTSF; HEGFL |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001945 edited
GAATTCGGCACGAGGGCTACGCGGGCCACGCTGCTGGCTGGCCTGACCTAGGCGCGCGGG GTCGGGCGGCCGCGCGGGCGGGCTGAGTGAGCAAGACAAGACACTCAAGAAGAGCGAGCT GCGCCTGGGTCCCGGCCAGGCTTGCACGCAGAGGCGGGCGGCAGACGGTGCCCGGCGGAA TCTCCTGAGCTCCGCCGCCCAGCTCTGGTGCCAGCGCCCAGTGGCCGCCGCTTCGAAAGT GACTGGTGCCTCGCCGCCTCCTCTCGGTGCGGGACCATGAAGCTGCTGCCGTCGGTGGTG CTGAAGCTCTTTCTGGCTGCAGTTCTCTCGGCACTGGTGACTGGCGAGAGCCTGGAGCGG CTTCGGAGAGGGCTAGCTGCTGGAACCAGCAACCCGGACCCTCCCACTGTATCCACGGAC CAGCTGCTACCCCTAGGAGGCGGCCGGGACCGGAAAGTCCGTGACTTGCAAGAGGCAGAT CTGGACCTTTTGAGAGTCACTTTATCCTCCAAGCCACAAGCACTGGCCACACCAAACAAG GAGGAGCACGGGAAAAGAAAGAAGAAAGGCAAGGGGCTAGGGAAGAAGAGGGACCCATGT CTTCGGAAATACAAGGACTTCTGCATCCATGGAGAATGCAAATATGTGAAGGAGCTCCGG GCTCCCTCCTGCATCTGCCACCCGGGTTACCATGGAGAGAGGTGTCATGGGCTGAGCCTC CCAGTGGAAAATCGCTTATATACCTATGACCACACAACCATCCTGGCCGTGGTGGCTGTG GTGCTGTCATCTGTCTGTCTGCTGGTCATCGTGGGGCTTCTCATGTTTAGGTACCATAGG AGAGGAGGTTATGATGTGGAAAATGAAGAGAAAGTGAAGTTGGGCATGACTAATTCCCAC TGAGAGAGACTTGTGCTCAAGGAATCGGCTGGGGACTGCTACCTCTGAGAAGACACAAGG TGATTTCAGACTGCAGAGGGGAAAGACTTCCATCTAGTCACAAAGACTCCTTCGTCCCCA GTTGCCGTCTAGGATTGGGCCTCCCATAATTGCTTTGCCAAAATACCAGAGCCTTCAAGT GCCAAACAGAGTATGTCCGATGGTATCTGGGTAAGAAGAAAGCAAAAGCAAGGGACCTTC ATGCCCTTCTGATTCCCCTCCACCAAACCCCACTTCCCCTCATAAGTTTGTTTAAACACT TATCTTCTGGATTAGAATGCCGGTTAAATTCCATATGCTCCAGGATCTTTGACTGAAAAA AAAAAAGAAGAAGAAGAAGGAGAGCAAGAAGGAAAGATTTGTGAACTGGAAGAAAGCAAC AAAGATTGAGAAGCCATGTACTCAAGTACCACCAAGGGATCTGCCATTGGGACCCTCCAG TGCTGGATTTGATGAGTTAACTGTGAAATACCACAAGCCTGAGAACTGAATTTTGGGACT TCTACCCAGATGGAAAAATAACAACTATTTTTGTTGTTGTTGTTTGTAAATGCCTCTTAA ATTATATATTTATTTTATTCTATGTATGTTAATTTATTTAGTTTTTAACAATCTAACAAT AATATTTCAAGTGCCTAGACTGTTACTTTGGCAATTTCCTGGCCCTCCACTCCTCATCCC CACAATCTGGCTTAGTGCCACCCACCTTTGCCACAAAGCTAGGATGGTTCTGTGACCCAT CTGTAGTAATTTATTGTCTGTCTACATTTCTGCAGATCTTCCGTGGTCAGAGTGCCACTG CGGGAGCTCTGTATGGTCAGGATGTAGGGGTTAACTTGGTCAGAGCCACTCTATGAGTTG GACTTCAGTCTTGCCTAGGCGATTTTGTCTACCATTTGTGTTTTGAAAGCCCAAGGTGCT GATGTCAAAGTGTAACAGATATCAGTGTCTCCCCGTGTCCTCTCCCTGTCAAGTCTCAGA AGAGGTTGGGCTTCCATGCCTGTAGCTTTCCTGGTCCCTCACCCCCATGGCCCCAGGCCC ACAGCGTGGGAACTCACTTTCCCTTGTGTCAAGACATTTCTCTAACTCCTGCCATTCTTC TGGTGCTACTCCATGCAGGGGTCAGTGCAGCAGAGGACAGTCTGGAGAAGGTATTAGCAA AGCAAAAGGCTGAGAAGGAACAGGGAACATTGGAGCTGACTGTTCTTGGTAACTGATTAC CTGCCAATTGCTACCGAGAAGGTTGGAGGTGGGGAAGGCTTTGTATAATCCCACCCACCT CACCAAAACGATGAAGTTATGCTGTCATGGTCCTTTCTGGAAGTTTCTGGTGCCATTTCT GAACTGTTACAACTTGTATTTCCAAACCTGGTTCATATTTATACTTTGCAATCCAAATAA AGATAACCCTTATTCCATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAACTCGAC >OriGene 5' read for NM_001945 unedited
NNNGGTTCGCATTTTGTAATACGACTTCACTATAGGGCGGCCGCGAATTCGCACGAGGGC TACGCGGGCCACGCTGCTGGCTGGCCTGACCTAGGCGCGCGGGGTCGGGCGGCCGCGCGG GCGGGCTGAGTGAGCAAGACAAGACACTCAAGAAGAGCGAGCTGCGCCTGGGTCCCGGCC AGGCTTGCACGCAGAGGCGGGCGGCAGACGGTGCCCGGCGGAATCTCCTGAGCTCCGCCG CCCAGCTCTGGTGCCAGCGCCCAGTGGCCGCCGCTTCGAAAGTGACTGGTGCCTCGCCGC CTCCTCTCGGTGCGGGACCATGAAGCTGCTGCCGTCGGTGGTGCTGAAGCTCTTTCTGGC TGCAGTTCTCTCGGCACTGGTGACTGGCGAGAGCCTGGAGCGGCTTCGGAGAGGGCTAGC TGCTGGAACCAGCAACCCGGACCCTCCCACTGTATCCACGGACCAGCTGCTACCCCTAGG AGGCGGCCGGGACCGGAAAGTCCGTGACTTGCAAGAGGCAGATCTGGACCTTTTGAGAGT CACTTTATCCTCCAAGCCACAAGCACTGGCCACACCAAACAAGGAGGAGCACGGGAAAAG AAAGAAGAAAGGCAAGGGGCTAGGGAAGAAGAGGGACCCATGTCTTCGGAAATACAAGGA CTTCTGCATCCATGGAGAATGCANATATGTGAAGGAGCTCCGGGCTCCCTCCTGCATCTG CCACCCGGGTTACCATGGAGAGAGGTGTCATGGGCTGAGCCTNCCAGTGGAAAATCGCTT ATATACCTATGACCACACACCATCCTGGCCGTGGTGGCTGTGGTGCTGTCATCTGTCTGT CTGCTGGTCATCGTGGGGCTTNCTCATGTTAGGTACCCATAGAGAGGGAGTNATGATGTN GNAAATGAAGAAC >OriGene 3' read for NM_001945 unedited
GGCACGCAATCTAGTATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTAAGGAATAAGGGTTTTTTTTTTTTGGATTGCAA AGTTTAAATATGAACCAGGTTTGGAAATACAAGTTGTAACAGTTCAAAAATGGCCCCAAA AACTTCCAAAAAGGACCCTGACAGCATAACTTCTTTGTTTTGGGGAGGGGGGGGGGATTA TACAAAGCCTTCCCCACCTTCAACCTTTTTGGGAGCAATTGGGAGGTAATTAGTTACCAA AAACAGGCAGCTCCAATGTTCCCTGTTCCTTTTAAACCTTTTGGTTTGGTAAAACCTTTT CCAAAATGTCCTTTGGTGGACTGACCCCTGGTTGGGGTACCCCCAAAAAAATGGGAGGAG TTAAAAAAATGTCTTGACACAAGGGAAAGGGAGTTCCCACCCTGGGGGCCTGGGGCCATG GGGGGGAGGGACCAAAAAAGCTACAGGCTTGGAAGCCCAACCTTTTTTGAAACTTGACAG GGAGAGGACACGGGGAAACACTGATTTTTGTTACACTTTGACATCAACACCTTGGGCTTT AAAAACACAAATGGGAGACAAAATCGCCTAGGGAAGACTGAAGTCCAACTCATAGAGGGG CTCTGACCAAGTTAACCCCTACATTCTGACCATACAAAGCTCCCGCAGTGGCACTTTGAC CCCGAAGATCTGCAAAATTGTTAACGGACAATTAATTTCTACAGATGGGTCCACAGACCA TCCTTACCTTTGTGCGAATGTGGGTGGCACTATACCATATTGGGGGATATAGATTGAAGG CCCCNAAAATGCCAAAGAACAGCTAGGCCCTTAAATTTATGGTAATTGGNAAACCTCATA TTTACCTCTTGAATAATAAATTTTTTTTAAGGGGCTTCCAACACACCACCAATTTTGTTA TTTCCTCGGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001945 |
| Insert Size | 2440 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001945.1, NP_001936.1 |
| RefSeq Size | 2360 bp |
| RefSeq ORF | 627 bp |
| Locus ID | 1839 |
| UniProt ID | Q99075 |
| Domains | EGF |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
| Protein Pathways | Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, GnRH signaling pathway |
| Gene Summary | Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207688 | HBEGF (Myc-DDK-tagged)-Human heparin-binding EGF-like growth factor (HBEGF) |
CNY 2,400.00 |
|
| RC207688L1 | Lenti ORF clone of Human heparin-binding EGF-like growth factor (HBEGF), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC207688L2 | Lenti ORF clone of Human heparin-binding EGF-like growth factor (HBEGF), mGFP tagged |
CNY 4,800.00 |
|
| RC207688L3 | Lenti ORF clone of Human heparin-binding EGF-like growth factor (HBEGF), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC207688L4 | Lenti ORF clone of Human heparin-binding EGF-like growth factor (HBEGF), mGFP tagged |
CNY 5,890.00 |
|
| RG207688 | HBEGF (tGFP-tagged) - Human heparin-binding EGF-like growth factor (HBEGF) |
CNY 4,000.00 |
