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PILRA (NM_013439) Human Untagged Clone
CAT＃: SC108389
PILRA (untagged)-Human paired immunoglobin-like type 2 receptor alpha (PILRA), transcript variant 1
CNY 3,600.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FDF03 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_013439, the custom clone sequence may differ by one or more nucleotides
ATGGGTCGGCCCCTGCTGCTGCCCCTACTGCCCTTGCTGCTGCCGCCAGCATTTCTGCAGCCTAGTGGCT CCACAGGATCTGGTCCAAGCTACCTTTATGGGGTCACTCAACCAAAACACCTCTCAGCCTCCATGGGTGG CTCTGTGGAAATCCCCTTCTCCTTCTATTACCCCTGGGAGTTAGCCACAGCTCCCGACGTGAGAATATCC TGGAGACGGGGCCACTTCCACAGGCAGTCCTTCTACAGCACAAGGCCGCCTTCCATTCACAAGGATTATG TGAACCGGCTCTTTCTGAACTGGACAGAGGGTCAGAAGAGCGGCTTCCTCAGGATCTCCAACCTGCAGAA GCAGGACCAGTCTGTGTATTTCTGCCGAGTTGAGCTGGACACACGGAGCTCAGGGAGGCAGCAGTGGCAG TCCATCGAGGGGACCAAACTCTCCATCACCCAGGCTGTCACGACCACCACCCAGAGGCCCAGCAGCATGA CTACCACCTGGAGGCTCAGTAGCACAACCACCACAACCGGCCTCAGGGTCACACAGGGCAAACGACGCTC AGACTCTTGGCACATAAGTCTGGAGACTGCTGTGGGGGTGGCAGTGGCTGTCACTGTGCTCGGAATCATG ATTTTGGGACTGATCTGCCTCCTCAGGTGGAGGAGAAGGAAAGGTCAGCAGCGGACTAAAGCCACAACCC CAGCCAGGGAACCCTTCCAAAACACAGAGGAGCCATATGAGAATATCAGGAATGAAGGACAAAATACAGA TCCCAAGCTAAATCCCAAGGATGACGGCATCGTCTATGCTTCCCTTGCCCTCTCCAGCTCCACCTCACCC AGAGCACCTCCCAGCCACCGTCCCCTCAAGAGCCCCCAGAACGAGACCCTGTACTCTGTCTTAAAGGCCT AA >OriGene 5' read for NM_013439 unedited
TCGGCTTTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCTCCACCCCTG GGAGGCAGAAGCCAGGCATAGCGCGCTGGCTAGGACTCCAGTACCGTGAAGGGAGGCAGT GAGAGCAGACATCTGTGCCTCATTCCTGATCTCAAGGGGAAAGCAAGAACAAGGGAGGCT TCCTCAGGATCTCGAACCTGCGGAAGGAGGACCAGTCTGTGTACTTCTGCCAAGTCCAGC TGGACATACAGATCAGGGAGGCTGTCGTGGCAGTCCATCAAGGGGACCCACCTCACCATC ACCCAGGCCCTCAGGCAGCCCCTCCACAGGGCCCCTCTCCTGCCTGGACAGCTCTGCTGG TCTCCCCGTCCCCTGGAGAAGAACAAGGCCATGGGTCGGCCCCTGCTGCTGCCCCTGCTG CTCCTGCTGCAGCCGCCAGCATTTCTGCAGCCTGGTGGCTCCACAGGATCTGGTCCAAGC TACCTTTATGGGGTCACTCAACCAAAACACCTCTCAGCCTCCATGGGTGGCTCTGTGGAA ATCCCCTTCTCCTTCTATTACCCCTGGGAGTTAGCCATAGTTCCCAACGTGAGAATATCC TGGAGACGGGGCCACTTCCACGGGCAGTCCTTCTACAGCACAAGGCCGCCTTCCATTCAC AAGGATTATGTGAACCGGCTCTTTCTGAACTGGACAGAGGGTCAGGAGAGCGGCTTCCTC AGGATCTCAAACCTGCGGAAGGAGGACCAGTCTGTGTATTTCTGCCGAGTCGAGCTGGAC ACCCGNAGATCAGGGAGGCAGCAGTTGCAGTCCATCAAGGGGACCAAACTCACCATCACC CCAGCTGTCACAACCACCACCACCTGGNAGGCCCAGCAGCACAACCACCATAGNCGGCCT CAGGNTCACAGAAAGCAAAGGGCACTCANAATCATGGCACCTAAGTCTGGCACTGCCATC AGGGNTGCATTGGCTGNCGCTGN >OriGene 3' read for NM_013439 unedited
NNTTTTTAGCTATGGACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTT AAATTTGTTACTTTATTGTTAATATATATTTTTAACTAGAGATGGCATCTCGCTCCATTA TCAAAGCTGGCCCTGAACTCCTGGGCTCACTTGATTCTGCCTCAGGCTTCAGAGTAGCTG GGATTACAGGTGTGCGCCACTGTACCTGGCCTCACCATTCAGTCTTGAGAGGGCTGTCCA TTGGTTAGGCCTTTAAGACAGAGTACAGGGTCTCGTTCTGGGGGCTCTTGAGGGGACGGT GGCTGGGAGGTGCTCTGGGTGAGGTGGAGCTGGAGAGGGCAAGGGAAGCATAGACGATGC CGTCATCCTTGGGATTTAGCTTGGGATCTGTATTTTGTCCTTCATTCCTGATATTCTCAT ATGGCTCCTCTGTGTTTTGGAAGGGTTCCCTGGCTGGGGTTGTGGCTTTAGTCCGCTGCT GACCTTTCCTTCTCCTCCACCTGAGGAGGCAGATCAGTCCCAAAATCATGATTCCGAGCA CAGTGACAGCCACTGCCACCCCCACAGCAGTCTCCAGACTTATGTGCCAAGAGTCTGAGC GTCGTTTGCCCTGTGTGACCCTGAGGCCGGTTGTGGTGGTTGTGCTACTGAGCCTCCAGG TGGTAGTCATGCTGCTGGGCCTCTGGGTGGTGGTCGTGACAGCCTGNGTGATGGAGAGNT TGGGTCCCCTCGATGGACTGCCACTGCTGCCTCCCTGAGCTNNCGTGTGTCCAGCTAAAC TCGGCAGAAAACACAGACTGGTCCTGCTTTGCAGTTTGGGAGATCTGGAGAAGCCGCTCT CTGACCTCTGTCCAGTCAGAAGAAGACGGTCACATATCTGTGAAAGGAAAGCGNCCTGGC TTTNAAAGGCTCGGTCGTGAATGGGCCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_013439 |
| Insert Size | 2190 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_013439.2, NP_038467.2 |
| RefSeq Size | 1323 bp |
| RefSeq ORF | 912 bp |
| Locus ID | 29992 |
| UniProt ID | Q9UKJ1 |
| Domains | IG |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Differential Effects on Cell Fusion Activity of Mutations in Herpes Simplex Virus 1 Glycoprotein B (gB) Dependent on Whether a gD Receptor or a gB Receptor Is Overexpressed
,Qing Fan, Erick Lin, Takeshi Satoh, Hisashi Arase, and Patricia G. Spear,
J. Virol., Aug 2009; 83: 7384 - 7390.
[PILRA]
|
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Differential Effects on Cell Fusion Activity of Mutations in Herpes Simplex Virus 1 Glycoprotein B (gB) Dependent on Whether a gD Receptor or a gB Receptor Is Overexpressed ▿
,null,
,PubMed ID 19457990
[PILRA]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222662 | PILRA (Myc-DDK-tagged)-Human paired immunoglobin-like type 2 receptor alpha (PILRA), transcript variant 1 |
CNY 3,600.00 |
|
| RC222662L1 | Lenti ORF clone of Human paired immunoglobin-like type 2 receptor alpha (PILRA), transcript variant 1, Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC222662L2 | Lenti ORF clone of Human paired immunoglobin-like type 2 receptor alpha (PILRA), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC222662L3 | Lenti ORF clone of Human paired immunoglobin-like type 2 receptor alpha (PILRA), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC222662L4 | Lenti ORF clone of Human paired immunoglobin-like type 2 receptor alpha (PILRA), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG222662 | PILRA (tGFP-tagged) - Human paired immunoglobin-like type 2 receptor alpha (PILRA), transcript variant 1 |
CNY 5,200.00 |
