United States
Germany
Japan
United Kingdom
China
Calnexin (CANX) (NM_001746) Human Untagged Clone
CAT＃: SC108288
CANX (untagged)-Human calnexin (CANX), transcript variant 1
CNY 6,624.00
| Cited in 3 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CNX; IP90; P90 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001746 edited
GGGTCGGGCCGCCTCCGCCTCTCTCTTTACTGCGGCGCGGGGCAAGGTGTGCGGGCGGGA AGGGGCACGGGCACCCCCGCGGTCCTCGGGAGGCTAGAGATCATGGAAGGGAAGTGGTTG CTGTGTATGTTACTGGTGCTTGGAACTGCTATTGTTGAGGCTCATGATGGACATGATGAT GATGTGATTGATATTGAGGATGACCTTGACGATGTCATTGAAGAGGTAGAAGACTCAAAA CCAGATACCACTGCTCCTCCTTCATCTCCCAAGGTTACTTACAAAGCTCCAGTTCCAACA GGGGAAGTATATTTTGCTGATTCTTTTGACAGAGGAACTCTGTCAGGGTGGATTTTATCC AAAGCCAAGAAAGACGATACCGATGATGAAATTGCCAAATATGATGGAAAGTGGGAGGTA GAGGAAATGAAGGAGTCAAAGCTTCCAGGTGATAAAGGACTTGTGTTGATGTCTCGGGCC AAGCATCATGCCATCTCTGCTAAACTGAACAAGCCCTTCCTGTTTGACACCAAGCCTCTC ATTGTTCAGTATGAGGTTAATTTCCAAAATGGAATAGAATGTGGTGGTGCCTATGTGAAA CTGCTTTCTAAAACACCAGAACTCAACCTGGATCAGTTCCATGACAAGACCCCTTATACG ATTATGTTTGGTCCAGATAAATGTGGAGAGGACTATAAACTGCACTTCATCTTCCGACAC AAAAACCCCAAAACGGGTATCTATGAAGAAAAACATGCTAAGAGGCCAGATGCAGATCTG AAGACCTATTTTACTGATAAGAAAACACATCTTTACACACTAATCTTGAATCCAGATAAT AGTTTTGAAATACTGGTTGACCAATCTGTGGTGAATAGTGGAAATCTGCTCAATGACATG ACTCCTCCTGTAAATCCTTCACGTGAAATTGAGGACCCAGAAGACCGGAAGCCCGAGGAT TGGGATGAAAGACCAAAAATCCCAGATCCAGAAGCTGTCAAGCCAGATGACTGGGATGAA GATGCCCCTGCTAAGATTCCAGATGAAGAGGCCACAAAACCCGAAGGCTGGTTAGATGAT GAGCCTGAGTACGTACCTGATCCAGACGCAGAGAAACCTGAGGATTGGGATGAAGACATG GATGGAGAATGGGAGGCTCCTCAGATTGCCAACCCTAGATGTGAGTCAGCTCCTGGATGT GGTGTCTGGCAGCGACCTGTGATTGACAACCCCAATTATAAAGGCAAATGGAAGCCTCCT ATGATTGACAATCCCAGTTACCAGGGAATCTGGAAACCCAGGAAAATACCAAATCCAGAT TTCTTTGAAGATCTGGAACCTTTCAGAATGACTCCTTTTAGTGCTATTGGTTTGGAGCTG TGGTCCATGACCTCTGACATTTTTTTTGACAACTTTATCATTTGTGCTGATCGAAGAATA GTTGATGATTGGGCCAATGATGGATGGGGCCTGAAGAAAGCTGCTGATGGGGCTGCTGAG CCAGGCGTTGTGGGGCAGATGAACGAGGCAGCTGAAGAGCGCCCGTGGCTGTGGGTAGTC TATATTCTAACTGTAGCCCTTCCTGTGTTCCTGGTTATCCTCTTCTGCTGTTCTGGAAAG AAACAGACCAGTGGTATGGAGTATAAGAAAACTGATGCACCTCAACCGGATGTGAAGGAA GAGGAAGAAGAGAAGGAAGAGGAAAAGGACAAGGGAGATGAGGAGGAGGAAGGAGAAGAG AAACTTGAAGAGAAACAGAAAAGTGATGCTGAAGAAGATGGTGGCACTGTCAGTCAAGAG GAGGAAGACAGAAAACCTAAAGCAGAGGAGGATGAAATTTTGAACAGATCACCAAGAAAC AGAAAGCCACGAAGAGAGTGAAACAATCTTAAGAGCTTGATCTGTGATTTCTTCTCCCTC CTCCCCTGCAAGAGTGGTCCTAGGAGAGGACCTGGCACACCTTAGGTTGACATTCAGAAA ACTTCAAGACATCACCATCAGCAGGCTCCAGTTGAACACTAGTCTGTGTAACTTTAAACA TCTAGCAGTAAATACTTGCAGTTGTGATATAAAGGACCCTGTTTCTGTAGAAAAGAAAAC ATTTAACATAATGGTTGTGAAATGTAACATGAAGCAAACTAACTTTTTTTTTTTTAACAT CTTTGTTTTTAAAATAGAATGATAGAACTTTGCCAGTCTTTAAGATCTTGGCTTAATTTA ATGTATTAATCTGTTTGTGCAAACATAATACCACCATTTAAAAATGTTAGGGAGATGAGT TGCAGTTTTTATAATAGATTTTTTTTAAAGTTTGGTATTGTAAAACATTCACACCTCTGT CCCTCAAAATTGATAATTACGTTTAAAGTGCAGTCATTTGTGGTTAGAATCTTGTTTTGT TTGCTTCCATTATTGAGTTCCTCCTAAGGAAATTGAGGAGAGGGACTGAATAGAAGCCCA AATTCATATAAAAGTTGCGTTTAAGTTGTATTAAAAATAGATATATAAGAAAAAATTCTT TCACTTGATGTTTGTTAGACCAGAAAGTGTGTGTGTTCTGTAGCTCAGTTCCCAGACAGC TTTTTAGGTAGTGGAGGAGGTGGCTTCATGTGGCACTTGGGCATTTATATTCCACTTGGG AGGGTCAGGCTGTGGCCTTCTGGAGCAGGTGGCTTGTTAAGGAACGCTAGCAGGGCATGG CACGTGAGCTCCGGAATAGATGTCTTCATCACTTCTTCCACTGTGTGTTGACACTGTTTT CCTTACCTATTTCCTCAGATCCCCAGCTTTCTCCTCTGCTATGCATTTTCTTCACAGTGC AGCTTGCAGTCCGTTGCTGAAAATGATTATAAGCCCTGCATAATGTTAAGCTTTATTGTG ATTACGTGTATGTTTCTTCTTTCTTTTAAGCAGACCCATACCTTTCCAGGGTCAAAGTAC AGAATAGAATACATTGATACAAAGTACAGAAAAATACTTTGATTTTTATCCATTTCTTTT ACTCTGTGTAAAGACTTGAGAAGTCTAATTCACAGGCAAACCAATACAGAATTGACTGCA GTTGAACAGACTAGAAGTATTTGTGGGAGGAGTGACATGAAGCATGAGTTATCTGATTTT TTTTGTAGCTGCTATATATTTTAAGCCTTCATTTGCAATTCATGTAACAGTTGTGTCATA AATTACACAATAAAGCAGTCCTGTTCAAATTTTTTTTTAACGTGGCTTGTAGAATTTTTA AAAAAGTGATCTTAGGTTTGTTTTTTCATGCGGGATGCAGATGGGTGCTATCAGAGCCTC TCCCACACCACTATAGTGTAATAATGTTATTATTACTCTACACTGAAACGTATTCAGAGT TAGATATTATTTTAGCTTCAGTTGTTCTTTAGAGGCTTTCAAATGTACCGATGATACTGT TTCTTGCACTGAATATATAAACACTCCACAGTGTTTATATTGGGAAGATATTGGGAAGGA AATATATTTGTAAAAGATGAAGGCTGTATCTATTTTTTTTTCTTTTTAAAGTTTGTTCAC TTAAATTCTTTTGAGGATGGGATGTATTTTTCTTGCTGTTCAGTGCTTTTTCCTTTTCAT CTGTTGTTCTGTGGTCACAGTGACCTTAGCTACATAGCAGACTTTCCCAAATGTATTGAT TACAAATAAACAGTTGTTACTTAGCAAGACCTGAAAATATGTCTGCAGGTTTCTCCTTGA AGCAAATGTGTGGGATCATTGCATTTCCAGAAATCTGCCTCCTTCACCCTCCGTTGACAG TATATGTCATGCCTCACTTTCTTCTAGCTGAGCTTTAAATCATTAGAGCTTAAATTGTCA GATCGTTCATTGCCTTTCCAGGGTTATTTAGTAAAGTTTGTTGAAAACAAAAACGCCTTT TCTTGGTTCTTTTTTCAGTTATTTTGAAGGTCCAGCATCCTGATTAAATGTCTGACACAT TAATGAATGACCAGCAGCAGCTTTCAGCTCTTAAAAAGACACTTATATTTTGATTTTACA TGCTGGTTACCTGTTCCATTGTTGTCAAATGCCCACTCTCCATCAGATGTGTTCCTCCAT TTTCTTATCCACAAAGTACTCCTCACTTTTCAATTTGTCATGTTACTAAATGGTGTTACA TTAAAGCCCTGTGTTAAGTGTC >OriGene 5' read for NM_001746 unedited
AACACTTAGGATTTTGTAACCGACTTCACTATAGGGCGGCCGCGCAATTCGCACGAGGGT CGGGCCGCCTCCGCCTCTCTCTTTACTGCGGCGCGGGGCAAGGTGTGCGGGCGGGAAGGG GCACGGGCACCCCCGCGGTCCTCGGGAGGCTAGAGATCATGGAAGGGAAGTGGTTGCTGT GTATGTTACTGGTGCTTGGAACTGCTATTGTTGAGGCTTATGATGGACATGATGATGATG TGATTGATATTGAGGATGACCTTGACGATGTCATTGAAGAGGTAGAAGACTCAAAACCAG ATACCACTGCTCCTCCTTCATCTCCCAAGGTTACTTACAAAGCTCCAGTTCCAACAGGGG AAGTATATTTTGCTGATTCTTTTGACAGAGGAACTCTGTCAGGGTGGATTTTATCCAAAG CCAAGAAAGACGATACCGATGATGAAATTGCCAAATATGATGGAAAGTGGGAGGTAGAGG AAATGAAGGAGTCAAAGCTTCCAGGTGATAAAGGACTTGTGTTGATGTCTCGGGCCAAGC ATCATGCCATCTCTGCTAAACTGAACAAGCCCTTCCTGTTTGACACCAAGCCTCTCATTG TTCAGTATGAGGTTAATTTCCAAAATGGAATAGAATGTGGTGGTGCCTATGTGAAACTGC TTTCTAAAACACCAGAACTCAACCTGGATCAGTTCCATNGACAGACCCCTTATACGATTA TGTTTGGTCCAGATNAATGTGGAGAGGACTATAAACTGCACTTCATCTTCCGACACANAA ACCCCAAAACGGGTATCTATGAAGAAAAACATNGCTAGAGGCCAGATGCAGATCTGAAGA CCTATTTTACTGATAAGAAACACATCCTTACCACTAATCTTGAATCAGAAATAGTTTTG >OriGene 3' read for NM_001746 unedited
CCCTTGCTCTGCNACCGCGGCCGCAATCTAANGATCGGTTTTTTTTTTTTTTTTTTGACA CTTAACACAGGNGCTTTAATGTAACACCATTTAGTAACATGACAAATTGAAAAGTGAGGA GTACTTTGTGGATAAGAAAATGGAGGAACACATCTGATGGAGAGTGGGCATTTGACAACA ATGGAACAGGTAACCAGCATGTAAAATCAAAATATAAGTGTCTTTTTAAGAGCTGAAAGC TGCTGCTGGTCATTCATTAATGTGTCAGACATTTAATCAGGATGCTGGACCTTCAAAATA ACTGAAAAAAGAACCAAGAAAAGGCGTTTTTGTTTTCAACAAACTTTACTAAATAACCCT GCAAAGGCAATGAACGATCTGACAATTTACACTCTAATGATTTAAAGCTCACCTAGAAGA AAGTGAGGCATGACATATACTGCCACCGGCAGGGCGACAGCGACGTCGATTTCTGGAAAT GCAACGATCCCACACATTTGTTTCAAGGACAACCCTGCACATATATTCTCAGGCCCTCGC TAACGCACACCTGCTTATTTGCGACCAACCACTCCGGCACCGCCCGCTCTGTACCTCACC GTACTGTGACCACCGAACCCCCTACGAACCGGCTCTCGCCCTGCTCCCCACGAAAAACAT CTCCCCTCCCCCAAAGAATCTATCCGAACAACCTTTTCAACGAAACAAACTCTCCTTCCC GCCTTATTTTTTACACACATATTCCCTTCCCCAACCTTTTCCCAACTAAACCTTGNGGGC GGCTTACTATCTTCCCCCCACGAACCCGCTTTCCTCGTCTCCCTCTGAAAGCCCCTCTAC GCACACCTTGCCCCTTACCCAATCACCTCAACCCCCGATACGTTCAATTGGTTTATACCA CCTTCCTCCTTTATTTTCTTCGCCGT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001746 |
| Insert Size | 4700 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001746.3, NP_001737.1 |
| RefSeq Size | 4953 bp |
| RefSeq ORF | 1779 bp |
| Locus ID | 821 |
| UniProt ID | P27824 |
| Domains | calreticulin |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Antigen processing and presentation |
| Gene Summary | This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2018] Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Green fluorescent protein-tagged apolipoprotein E: A useful marker for the study of hepatic lipoprotein egress
,Takacs, CN;Andreo, U;Belote, RL;Pulupa, J;Scull, MA;Gleason, CE;Rice, CM;Simon, SM;,
Traffic
,PubMed ID 28035714
[CANX]
|
|
Suppression of Cytochrome P450 3A4 Function by UDP-Glucuronosyltransferase (UGT) 2B7 through a Protein-Protein Interaction: Cooperative Roles of the Cytosolic Carboxyl-Terminal Domain and the Luminal Anchoring Region of UGT2B7
,Miyauchi, Y;Nagata, K;Yamazoe, Y;Mackenzie, PI;Yamada, H;Ishii, Y;,
Mol. Pharmacol.
,PubMed ID 26243732
[CANX]
|
|
Non-invasive intravital imaging of cellular differentiation with a bright red-excitable fluorescent protein
,Chu, J;Haynes, RD;Corbel, SY;Li, P;González-González, E;Burg, JS;Ataie, NJ;Lam, AJ;Cranfill, PJ;Baird, MA;Davidson, MW;Ng, HL;Garcia, KC;Contag, CH;Shen, K;Blau, HM;Lin, MZ;,
Nat. Methods
,PubMed ID 24633408
[CANX]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200229 | CANX (Myc-DDK-tagged)-Human calnexin (CANX), transcript variant 1 |
CNY 6,608.00 |
|
| RC200229L1 | Lenti ORF clone of Human calnexin (CANX), transcript variant 1, Myc-DDK-tagged |
CNY 9,008.00 |
|
| RC200229L2 | Lenti ORF clone of Human calnexin (CANX), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC200229L3 | Lenti ORF clone of Human calnexin (CANX), transcript variant 1, Myc-DDK-tagged |
CNY 9,008.00 |
|
| RC200229L4 | Lenti ORF clone of Human calnexin (CANX), transcript variant 1, mGFP tagged |
CNY 9,008.00 |
|
| RG200229 | CANX (tGFP-tagged) - Human calnexin (CANX), transcript variant 1 |
CNY 8,208.00 |
其它Calnexin产品
