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PPAR gamma (PPARG) (NM_138711) Human Untagged Clone
CAT＃: SC108192
PPARG (untagged)-Human peroxisome proliferator-activated receptor gamma (PPARG), transcript variant 3
CNY 4,760.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_138711 edited
CAGAAGCCTGCATTTCTGCATTCTGCTTAATTCCCTTTCCTTAGATTTGAAAGAAGCCAA CACTAAACCACAAATATACAACAAGGCCATTTTCTCAAACGAGAGTCAGCCTTTAACGAA ATGACCATGGTTGACACAGAGATGCCATTCTGGCCCACCAACTTTGGGATCAGCTCCGTG GATCTCTCCGTAATGGAAGACCACTCCCACTCCTTTGATATCAAGCCCTTCACTACTGTT GACTTCTCCAGCATTTCTACTCCACATTACGAAGACATTCCATTCACAAGAACAGATCCA GTGGTTGCAGATTACAAGTATGACCTGAAACTTCAAGAGTACCAAAGTGCAATCAAAGTG GAGCCTGCATCTCCACCTTATTATTCTGAGAAGACTCAGCTCTACAATAAGCCTCATGAA GAGCCTTCCAACTCCCTCATGGCAATTGAATGTCGTGTCTGTGGAGATAAAGCTTCTGGA TTTCACTATGGAGTTCATGCTTGTGAAGGATGCAAGGGTTTCTTCCGGAGAACAATCAGA TTGAAGCTTATCTATGACAGATGTGATCTTAACTGTCGGATCCACAAAAAAAGTAGAAAT AAATGTCAGTACTGTCGGTTTCAGAAATGCCTTGCAGTGGGGATGTCTCATAATGCCATC AGGTTTGGGCGGATGCCACAGGCCGAGAAGGAGAAGCTGTTGGCGGAGATCTCCAGTGAT ATCGACCAGCTGAATCCAGAGTCCGCTGACCTCCGGGCCCTGGCAAAACATTTGTATGAC TCATACATAAAGTCCTTCCCGCTGACCAAAGCAAAGGCGAGGGCGATCTTGACAGGAAAG ACAACAGACAAATCACCATTCGTTATCTATGACATGAATTCCTTAATGATGGGAGAAGAT AAAATCAAGTTCAAACACATCACCCCCCTGCAGGAGCAGAGCAAAGAGGTGGCCATCCGC ATCTTTCAGGGCTGCCAGTTTCGCTCCGTGGAGGCTGTGCAGGAGATCACAGAGTATGCC AAAAGCATTCCTGGTTTTGTAAATCTTGACTTGAACGACCAAGTAACTCTCCTCAAATAT GGAGTCCACGAGATCATTTACACAATGCTGGCCTCCTTGATGAATAAAGATGGGGTTCTC ATATCCGAGGGCCAAGGCTTCATGACAAGGGAGTTTCTAAAGAGCCTGCGAAAGCCTTTT GGTGACTTTATGGAGCCCAAGTTTGAGTTTGCTGTGAAGTTCAATGCACTGGAATTAGAT GACAGCGACTTGGCAATATTTATTGCTGTCATTATTCTCAGTGGAGACCGCCCAGGTTTG CTGAATGTGAAGCCCATTGAAGACATTCAAGACAACCTGCTACAAGCCCTGGAGCTCCAG CTGAAGCTGAACCACCCTGAGTCCTCACAGCTGTTTGCCAAGCTGCTCCAGAAAATGACA GACCTCAGACAGATTGTCACGGAACACGTGCAGCTACTGCAGGTGATCAAGAAGACGGAG ACAGACATGAGTCTTCACCCGCTCCTGCAGGAGATCTACAAGGACTTGTACTAGCAGAGA GTCCTGAGCCACTGCCAACATTTCCCTTCTTCCAGTTGCACTATTCTGAGGGAAAATCTG ACACCTAAGAAATTTACTGTGAAAAAGCATTTTAAAAAGAAAAGGTTTTAGAATATGATC TATTTTATGCATATTGTTTATAAAGACACATTTACAATTTACTTTTAATATTAAAAATTA CCATATTATGAAA >OriGene 5' read for NM_138711 unedited
CCATATGTATACGACTCACTTATAGGGCGGCCGCGATTCGGCACGAGCAGAAGCCTGCAT TTCTGCATTCTGCTTAATTCCCTTTCCTTAGATTTGAAAGAAGCCAACACTAAACCACAA ATATACAACAAGGCCATTTTCTCAAACGAGAGTCAGCCTTTAACGAAATGACCATGGTTG ACACAGAGATGCCATTCTGGCCCACCAACTTTGGGATCAGCTCCGTGGATCTCTCCGTAA TGGAAGACCACTCCCACTCCTTTGATATCAAGCCCTTCACTACTGTTGACTTCTCCAGCA TTTCTACTCCACATTACGAAGACATTCCATTCACAAGAACAGATCCAGTGGTTGCAGATT ACAAGTATGACCTGAAACTTCAAGAGTACCAAAGTGCAATCAAAGTGGAGCCTGCATCTC CACCTTATTATTCTGAGAAGACTCAGCTCTACAATAAGCCTCATGAAGAGCCTTCCAACT CCCTCATGGCAATTGAATGTCGTGTCTGTGGAGATAAAGCTTCTGGATTTCACTATGGAG TTCATGCTTGTGAAGGATGCAAGGGTTTCTTCCGGAGAACAATCAGATTGAAGCTTATCT ATGACAGATGTGATCTTAACTGTCGGATCCACAAAAAAAGTAGAAATAAATGTCAGTACT GTCGGTTTCAGAAATGCCTTGCAGTGNGGATGTCTCATAATGCCATCAGGTTTGGGCGGA TGCCACAGGCCGAGAAGGAGAAGCTGTTGGCGGAGATCTCCAGTGATATCGACCAGCTGA ATCCAGAGTCCGCTGACCTCCGGGCCCTGGCAAACATTNGTATGACTCATACATAAAGTC CTTCCCGCTGACCAAAGCANAGGCGAGGNCGATCTTGACAGGAANNGACACAGACAATCA CCATTCGTTATCTATGACATGAANNTCCTTATGATGGNAGAAGATANAATCAAGTTCAAC ACTCACCCCCCTGCAGGAGCAGACCAAGAGG >OriGene 3' read for NM_138711 unedited
ATCTNTGNNACCGCGGCCGCAATTCTANGATCGAGTTTTTTTTTTTTTTTTTTTCATAAT ATGGTAATTTTTAATATTAAAAGTAAATTGTAAATGTGTCTTTATAAACAATATGCATAA AATAGATCATATTCTAAAACCTTTTCTTTTTAAAATGCTTTTTCACAGTAAATTTCTTAG GTGTCAGATTTTCCCTCAGAATAGTGCAACTGGAAGAAGGGAAATGTTGGCAGTGGCTCA GGACTCTCTGCTAGTACAAGTCCTTGTAGATCTCCTGCAGGAGCGGGTGAAGACTCATGT CTGTCTCCGTCTTCTTGATCACCTGCAGTAGCTGCACGTGTTCCGTGACAATCTGTCTGA GGTCTGTCATTTTCTGGAGCAGCTTGGCAAACAGCTGTGAGGACTCAGGGTGGTTCAGCT TCAGCTGGAGCTCCAGGGCTTGTAGCAGGTTGTCTTGAATGTCTTCAATGGGCTTCACAT TCAGCAAACCTGGGCGGTCTCCACTGAGAATAATGACAGCAATAAATATTGCCAAGTCGC TGTCATCTAATTCCAGTGCATTGAACTTCACAGCAAACTCAAACTTGGGCTNCATAAAGT CACCAAAAGGCTTTCGCAGGCTCTTTAGAAACTCCCTTGTCATGAAGCCTTGGCCCTCGG ATATGAGAACCCCATCTTTATTCATCAAGGAGGCCAGCATTGTGTAAATGATCCCGTGGA CTCCATATTTGAGGAGAGGTACTTGGGCCGTTCAAGTCAGGATTACAAAACCAGGATGCT TTTNGCATACTCTGTGAACTCCTGCCCAGCCTCCCGGAGCGAAACTGCAGCCCTGAAGAT GCGGATGGCCACCTTTTGCTCTGCTCTGCAGGGGGTGATGTGTTNGAACCTTGATTTTCC TCTCCATCCTTAGGGAATCATGGCAAGATACCAAGGGGATTTGCCTGGTGGCTTTCTGGC AAGACCGCCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_138711 |
| Insert Size | 1800 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_138711.2, NP_619725.1 |
| RefSeq Size | 1920 bp |
| RefSeq ORF | 1919 bp |
| Locus ID | 5468 |
| UniProt ID | P37231 |
| Domains | HOLI, zf-C4 |
| Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
| Protein Pathways | Huntington's disease, Pathways in cancer, PPAR signaling pathway, Thyroid cancer |
| Gene Summary | This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (3) differs in the 5' UTR and 5' coding region compared to variant 2. Variants 1, 3, 4, 6, and 7 all encode the same isoform (1), which has a shorter, distinct N-terminus compared to isoform 2. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation
,Halstead, AM;Kapadia, CD;Bolzenius, J;Chu, CE;Schriefer, A;Wartman, LD;Bowman, GR;Arora, VK;,
Elife
,PubMed ID 29143738
[PPARG]
|
|
The EWSR1/NR4A3 fusion protein of extraskeletal myxoid chondrosarcoma activates the PPARG nuclear receptor gene
,null,
The Journal of pathology
,PubMed ID 18855877
[PPARG]
|
Documents
| Product Manuals |
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC212181 | PPARG (Myc-DDK-tagged)-Human peroxisome proliferator-activated receptor gamma (PPARG), transcript variant 3 |
CNY 3,656.00 |
|
| RC212181L1 | Lenti ORF clone of Human peroxisome proliferator-activated receptor gamma (PPARG), transcript variant 3, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC212181L2 | Lenti ORF clone of Human peroxisome proliferator-activated receptor gamma (PPARG), transcript variant 3, mGFP tagged |
CNY 6,056.00 |
|
| RC212181L3 | Lenti ORF clone of Human peroxisome proliferator-activated receptor gamma (PPARG), transcript variant 3, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC212181L4 | Lenti ORF clone of Human peroxisome proliferator-activated receptor gamma (PPARG), transcript variant 3, mGFP tagged |
CNY 5,890.00 |
|
| RG212181 | PPARG (tGFP-tagged) - Human peroxisome proliferator-activated receptor gamma (PPARG), transcript variant 3 |
CNY 5,256.00 |
|
| SC317789 | PPARG (untagged)-Human peroxisome proliferator-activated receptor gamma (PPARG), transcript variant 3 |
CNY 7,220.00 |
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