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PEA15 (NM_003768) Human Untagged Clone
CAT＃: SC108132
PEA15 (untagged)-Human phosphoprotein enriched in astrocytes 15 (PEA15)
CNY 1,800.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HMAT1; HUMMAT1H; MAT1; MAT1H; PEA-15; PED; PED-PEA15; PED/PEA15 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_003768 edited
ATGGCTGAGTACGGGACCCTCCTGCAAGACCTGACCAACAACATCACCCTTGAAGATCTA GAACAGCTCAAGTCGGCCTGCAAGGAAGACATCCCCAGCGAAAAGAGTGAGGAGATCACT ACTGGCAGTGCCTGGTTTAGCTTCCTGGAGAGCCACAACAAGCTGGACAAAGACAACCTC TCCTACATTGAGCACATCTTTGAGATCTCCCGCCGTCCTGACCTACTCACTATGGTGGTT GACTACAGAACCCGTGTGCTGAAGATCTCTGAGGAGGATGAGCTGGACACCAAGCTAACC CGTATCCCCAGTGCCAAGAAGTACAAAGACATTATCCGGCAGCCCTCTGAGGAAGAGATC ATCAAATTGGCTCCCCCACCGAAGAAGGCCTGA >OriGene 5' read for NM_003768 unedited
GTTTCAGAATTTGTAATACGACTTCACTATANNGGCGGCCGCGCAATTCGGCACGAGGGG ACGCTGCTTAGGAACCGGGGACTCAGGAGTGCCCGCGCCCTGAGCGCTCAGCTCCAGAGG CGTCATGGCTGAGTACGGGACCCTCCTGCAAGACCTGACCAACAACATCACCCTTGAAGA TCTAGAACAGCTCAAGTCGGCCTGCAAGGAAGACATCCCCAGCGAAAAGAGTGAGGAGAT CACTACTGGCAGTGCCTGGTTTAGCTTCCTGGAGAGCCACAACAAGCTGGACAAAAGACA ACCTCTCCTACATTGAGCACATCTTTGAGATCTCCCGCCGTCCTGACCTACTCACTATGG TGGTTGACTACAGAACCCGTGTGCTGAAGATCTCTGAGGAGGATGAGCTGGACACCAAGC TAACCCGTATCCCCAGTGCCAAGAAGTACAAAGACATTATCCGGCAGCCCTCTGAGGAAG AGATCATCAAATTGGCTCCCCCACCGAAGAAGGCCTGAGCAAGGGGGAGGAAGAGGAGGA AGGTTGGACCTTCATCAGACCACTCCCTTCCCCCATCCTCCAGGAGAGGGGGCAAGGGCA ACCCACCATCTACCCACTTACTAACCTGGTCCTAACCCCCTTACTGTGCGCGTGTGTGTG CGTGTGCGCACGCTCTGGCTGTTTGTCTATATGTCTAGCTCATCTAGTTCCTCTTCTTAA GGGATGGGGGTCACGCGCTAGGGGGAGGGGCCTGAGTTTCCCCACTTTAAGAGGAAGTGG GGGCTATTCTATGCAAATAGAAATCAGCACATTCCTTCTACTTTCCTTTTCTCAACTCCC CCATATCTTTAAAGTGTGGAAGCCAGAAGGACCTGCATTTTCCTACATTTGAGAGCTGAC ATANGGGTTACGTATGGAGAG >OriGene 3' read for NM_003768 unedited
GAACGCCGCCGCTTACTANATCGAGTTTTTTTTTTTTTTTTTTGGCAGTGCAGTTTTAAT ATACATATATGTAGAATATATATGTACACACAGTTAGCACGGTCAGGGTGGGGAGGGGCA TCTTGGGGTAGGCAGGAGGCTGGGGTCACTCACTGTACTGTAGTGATGTGGCTAGGAGGT GTTCACAAGCCCAGGGGGCCAGGATATCTAGTAAAGAAGGGTTTCCTAAGTAAGTCCCTT CCGGGATTGAATTGGGGTGGGGATCGGTGCAAAGGAAAACACTGTAGTTAACTTCTTTCT GGCTTGGGATGTTCTTCACCAAGGAGAGAGGGAAGGTTGCCTACAATAACCAAGTTGGGA CCCTATAGATGGTGGTGTCAGGATTCGTGTTAAAACCTAAGGGTCTCATTCTTCAACCTC CCTAGGTTTAGAGTGCAACAGTCTGAGTAGGAACAACTGAGTGGAAGAGGGGGCTCCCCT CTCTCTGCCCTCATCCCCATCTCAGGCTCAGTGGTACATGTTCCCAGCACAGTCTCTCCA GAGTACAGGTGGGTGGGGGCATCTAACGCTGGCTGCTCCATGGGGTTTGATCTTAGGGAC CAGGAAAGGATCCCTGGCTCATACCTATGCTAGGCCCATGAGAGACAAAAAGGGACCTGC TGGTACTCANGAAACAGTCCAGCACAGGAGTACAAACATGGAACTCTGGCTTTTCTTTGC CCCTTCCAGGTGGGGGTTGAAGTGGTCTCTTTGCCTTTCGTCCCCACTGCTTTTTCCTGG ATCCACCCTACTCTNCCATACCTTACCCCTATGTCAGCTCCTCAATGTAGGAAAATGCAN GTTCTTTCTGCTTCCACACTTAAAGAATGGGGGGAGTGGAGGAAAGGAANTAGAAGNATG TGCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003768 |
| Insert Size | 1700 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_003768. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_003768.2, NP_003759.1 |
| RefSeq Size | 2486 bp |
| RefSeq ORF | 393 bp |
| Locus ID | 8682 |
| UniProt ID | Q15121 |
| Domains | DED |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] Transcript Variant: This variant (2) lacks two alternate exons in the 5' region and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus than isoform a. Variants 2 and 3 encode the same isoform (b). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
PTEN Loss Promotes Mitochondrially Dependent Type II Fas-Induced Apoptosis via PEA-15
,James W. Peacock, Jodie Palmer, Dieter Fink, Stephen Ip, Eric M. Pietras, Alice L.-F. Mui, Stephen W. Chung, Martin E. Gleave, Michael E. Cox, Ramon Parsons, Marcus E. Peter, and Christopher J. Ong,
Mol. Cell. Biol., Mar 2009; 29: 1222 - 1234.
[PEA15]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205507 | PEA15 (Myc-DDK-tagged)-Human phosphoprotein enriched in astrocytes 15 (PEA15) |
CNY 1,800.00 |
|
| RC205507L1 | Lenti ORF clone of Human phosphoprotein enriched in astrocytes 15 (PEA15), Myc-DDK-tagged |
CNY 4,200.00 |
|
| RC205507L2 | Lenti ORF clone of Human phosphoprotein enriched in astrocytes 15 (PEA15), mGFP tagged |
CNY 5,890.00 |
|
| RC205507L3 | Lenti ORF clone of Human phosphoprotein enriched in astrocytes 15 (PEA15), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC205507L4 | Lenti ORF clone of Human phosphoprotein enriched in astrocytes 15 (PEA15), mGFP tagged |
CNY 5,890.00 |
|
| RG205507 | PEA15 (tGFP-tagged) - Human phosphoprotein enriched in astrocytes 15 (PEA15) |
CNY 3,400.00 |
