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HNRPM (HNRNPM) (NM_031203) Human Untagged Clone
CAT＃: SC107969
HNRNPM (untagged)-Human heterogeneous nuclear ribonucleoprotein M (HNRNPM), transcript variant 2
CNY 5,072.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CEAR; hnRNP M; HNRNPM4; HNRPM; HNRPM4; HTGR1; NAGR1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC107969 sequence for NM_031203 edited (data generated by NextGen Sequencing)
ATGGCGGCAGGGGTCGAAGCGGCGGCGGAGGTGGCGGCGACGGAGATCAAAATGGAGGAA GAGAGCGGCGCGCCCGGCGTGCCGAGCGGCAACGGGGCTCCGGGCCCTAAGGGTGAAGGA GAACGACCTGCTCAGAATGAGAAGAGGAAGGAGAAAAACATAAAAAGAGGAGGCAATCGC TTTGAGCCATATGCCAATCCAACTAAAAGATACAGAGCCTTCATTACAAACATACCTTTT GATGTGAAATGGCAGTCACTTAAAGACCTGGTTAAAGAAAAAGTTGGTGAGGTAACATAC GTGGAGCTCTTAATGGACGCTGAAGGAAAGTCAAGGGGATGTGCTGTTGTTGAATTCAAG ATGGAAGAGAGCATGAAAAAAGCTGCGGAAGTCCTAAACAAGCATAGTCTGAGCGGAAGA CCACTGAAAGTCAAAGAAGATCCTGATGGTGAACATGCCAGGAGAGCAATGCAAAAGGCT GGAAGACTTGGAAGCACAGTATTTGTAGCAAATCTGGATTATAAAGTTGGCTGGAAGAAA CTGAAGGAAGTATTTAGTATGGCTGGTGTGGTGGTCCGAGCAGACATTCTTGAAGATAAA GATGGAAAAAGTCGTGGAATAGGCACTGTTACTTTTGAACAGTCCATTGAAGCTGTGCAA GCTATATCTATGTTCAATGGCCAGCTGCTATTTGATAGACCAATGCACGTCAAGATGGAT GAGAGGGCCTTACCAAAAGGAGATTTCTTCCCTCCTGAGCGTCCACAACAACTTCCCCAT GGCCTTGGTGGTATTGGCATGGGGTTAGGACCAGGAGGGCAACCCATTGATGCCAATCAC CTGAATAAAGGCATCGGAATGGGAAACATAGGTCCCGCAGGAATGGGAATGGAAGGCATA GGATTTGGAATAAATAAAATGGGAGGAATGGAGGGGCCCTTTGGTGGTGGTATGGAAAAC ATGGGTCGATTTGGATCTGGGATGAACATGGGCAGGATAAATGAAATCCTAAGTAATGCA CTGAAGAGAGGAGAGATCATTGCAAAGCAGGGAGGAGGTGGAGGTGGAGGAAGCGTCCCT GGGATCGAGAGGATGGGTCCTGGCATTGACCGCCTCGGGGGTGCCGGCATGGAGCGCATG GGCGCGGGCCTGGGCCACGGCATGGATCGCGTGGGCTCCGAGATCGAGCGCATGGGCCTG GTCATGGACCGCATGGGCTCCGTGGAGCGCATGGGCTCCGGCATTGAGCGCATGGGCCCG CTGGGCCTCGACCACATGGCCTCCAGCATTGAGCGCATGGGCCAGACCATGGAGCGCATT GGCTCTGGCGTGGAGCGCATGGGTGCCGGCATGGGCTTCGGCCTTGAGCGCATGGCCGCT CCCATCGACCGTGTGGGCCAGACCATTGAGCGCATGGGCTCTGGCGTGGAGCGCATGGGC CCTGCCATCGAGCGCATGGGCCTGAGCATGGAGCGCATGGTGCCCGCAGGTATGGGAGCT GGCCTGGAGCGCATGGGCCCCGTGATGGATCGCATGGCCACCGGCCTGGAGCGCATGGGC GCCAACAATCTGGAGCGGATGGGCCTGGAGCGCATGGGCGCCAACAGCCTCGAGCGCATG GGCCTGGAGCGCATGGGTGCCAACAGCCTCGAGCGCATGGGCCCCGCCATGGGCCCGGCC CTGGGCGCTGGCATTGAGCGCATGGGCCTGGCCATGGGTGGCGGTGGCGGTGCCAGCTTT GACCGTGCCATCGAGATGGAGCGTGGCAACTTCGGAGGAAGCTTCGCAGGTTCCTTTGGT GGAGCTGGAGGCCATGCTCCTGGGGTGGCCAGGAAGGCCTGCCAGATATTTGTGAGAAAT CTGCCATTCGATTTCACATGGAAGATGCTAAAGGACAAATTCAACGAGTGCGGCCACGTG CTGTACGCCGACATCAAGATGGAGAATGGGAAGTCCAAGGGGTGTGGTGTGGTTAAGTTC GAGTCGCCAGAGGTGGCCGAGAGAGCCTGCCGGATGATGAATGGCATGAAGCTGAGTGGC CGAGAGATTGACGTTCGAATTGATAGAAACGCTTAA Clone variation with respect to NM_031203.3 1665 t=>c;1968 c=>t >OriGene 5' read for NM_031203 unedited
TTCACATTTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGAATGGCGGCAGG GGTCGAAGCGGCGGCGGAGGTGGCGGCGACGGAGATCAAAATGGAGGAAGAGAGCGGCGC GCCCGGCGTGCCGAGCGGCAACGGGGCTCCGGGCCCTAAGGGTGAAGGAGAACGACCTGC TCAGAATGAGAAGAGGAAGGAGAAAAACATAAAAAGAGGAGGCAATCGCTTTGAGCCATA TGCCAATCCAACTAAAAGATACAGAGCCTTCATTACAAACATACCTTTTGATGTGAAATG GCAGTCACTTAAAGACCTGGTTAAAGAAAAAGTTGGTGAGGTAACATACGTGGAGCTCTT AATGGACGCTGAAGGAAAGTCAAGGGGATGTGCTGTTGTTGAATTCAAGATGGAAGAGAG CATGAAAAAAGCTGCGGAAGTCCTAAACAAGCATAGTCTGAGCGGAAGACCACTGAAAGT CAAAGAAGATCCTGATGGTGAACATGCCAGGAGAGCAATGCAAAAGGCTGGAAGACTTGG AAGCACAGTATTTGTAGCANATCTGGATTATANAGTTGGCTGGNAGAAACTGANNNGAGT ATTTAGTATGGCTGGTGTGGTGGTCCGAGCAGACATTCTTNGAGATAAAGATGGGAAAAG TCGNTGGATANGCACTGGTACTTNTTGACAGTCCCATTGAGCTGTGNCAGCTATATCTAT GTTCAATGGCCAGCTGCTATTTGATAGACCCATGCACCGTCAGATGGATTGAGAGGCCNT ACCAAAAAGAGAATTTTCTTCCTNCTGAGCGTCCACANCAACCTCCCCATGGGCCTNGTT GTATTGGCCATGGGGTTAGGCCCAGAAGGCACCCCATTGATGCCATCACCTGAATAAAGC ATCCGGAATGGGAACTAAGGTCCGCCGGGATGGGAATGGAAG >OriGene 3' read for NM_031203 unedited
TCTGGACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTCAGGAACCG GTATTTATTATCAAAGTCATATTCGATGTCAACAAGATGCCACAACTACAAAAAAAATTG CGCACATTGCAATCTCAATGCAAACAGTCAAATGGAACCCCAGTCATTAAAAAAGTAATT CAAATTACCCCAAAAAGCAACTGAATTTTTTAAACATCTTTATACATCCAGCCAACAAAT TAAAATGGTTAACAAGAAAAAATACAAATTCAGAGGTCTCGTATCGATGTTTAAAAAAGG CAACTGCTTAAGCGTTTCTATCAATTCGAACGTCAATCTCTCGGCCACTCAGCTTCATGC CATTCATCATCCGGCAGGCTCTCTCGGCCACCTCTGGCGACTCGAACTTAACCACACCAC ACCCCTTGGACTTCCCATTCTCCATCTTGATGTCGGCGTACAGCACGTGGCCGCACTCGT TGAATTTGTCCTTTAGCATCTTCCATGTGAAATCGAATGGCAGATTTCTCACAAATATCT GGCAGGCCTTCCTGGCCACCCCAGGAGCATGGCCTCCAGCTCCACCAAAGGAACCTGCGA AGCTTCCTCCGAAGTTGCCACGCTCCATCTCGATGGCACGGTCAAAGCTGGCACCGCCAC CGCCACCCATGGCCAGGCCCATGCGCTCAATGCCAGCGCCCAGGGCCGGGCCCATGGCGG GGCCCATGCGCTCGAGGCTGTTGGCACCCATGCGCTNCAGGCCCATGCGCTCGAGGCTTG TGGCGCCCATGCGCTCCAGGCCCATCCGCTCCAGATTTGTGGCGCCCATGCGCTNCAGGC CGNTGGCCATGCGATCCATCACGGGGCCNATGCGCNTCAGCCAGCNCCATTACTGNGGGC ACATGCGCTCATGCTNCAGCCATGCGCTCGATGCAGGGCCATGCGCTCCACGCAGAGCCA TGCGCTCATGGTCTGCCCAACNGTCGATGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_031203 |
| Insert Size | 2380 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_031203.1, NP_112480.1 |
| RefSeq Size | 2586 bp |
| RefSeq ORF | 2076 bp |
| Locus ID | 4670 |
| UniProt ID | P52272 |
| Domains | RRM |
| Protein Families | Druggable Genome |
| Protein Pathways | Spliceosome |
| Gene Summary | This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011] Transcript Variant: This variant (2) lacks an in-frame segment in the coding region, compared to variant 1. This results in a shorter protein (isoform b), compared to isoform a. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Heterogeneous nuclear ribonucleoprotein M promotes the progression of breast cancer by regulating the axin/β-catenin signaling pathway.
,null,
Biomedicine pharmacotherapy = Biomedecine pharmacotherapie
,PubMed ID 30021377
[HNRNPM]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC220513 | HNRNPM (Myc-DDK-tagged)-Human heterogeneous nuclear ribonucleoprotein M (HNRNPM), transcript variant 2 |
CNY 5,064.00 |
|
| RC220513L1 | Lenti ORF clone of Human heterogeneous nuclear ribonucleoprotein M (HNRNPM), transcript variant 2, Myc-DDK-tagged |
CNY 7,464.00 |
|
| RC220513L2 | Lenti ORF clone of Human heterogeneous nuclear ribonucleoprotein M (HNRNPM), transcript variant 2, mGFP tagged |
CNY 9,220.00 |
|
| RC220513L3 | Lenti ORF clone of Human heterogeneous nuclear ribonucleoprotein M (HNRNPM), transcript variant 2, Myc-DDK-tagged |
CNY 9,220.00 |
|
| RC220513L4 | Lenti ORF clone of Human heterogeneous nuclear ribonucleoprotein M (HNRNPM), transcript variant 2, mGFP tagged |
CNY 9,220.00 |
|
| RG220513 | HNRNPM (tGFP-tagged) - Human heterogeneous nuclear ribonucleoprotein M (HNRNPM), transcript variant 2 |
CNY 6,664.00 |
