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Cofilin 2 (CFL2) (NM_138638) Human Untagged Clone
CAT＃: SC107636
CFL2 (untagged)-Human cofilin 2 (muscle) (CFL2), transcript variant 2
CNY 2,400.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | NEM7 |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_138638, the custom clone sequence may differ by one or more nucleotides
ATGGCTTCTGGAGTTACAGTGAATGATGAAGTCATCAAAGTTTTTAATGATATGAAAGTAAGGAAATCTT CTACACAAGAGGAGATCAAAAAGAGAAAGAAAGCAGTTCTCTTCTGTTTAAGCGATGACAAAAGACAAAT AATTGTAGAGGAAGCAAAGCAGATCTTGGTGGGTGACATTGGTGATACTGTAGAGGACCCCTACACATCT TTTGTGAAGTTGCTACCTCTGAATGATTGCCGATATGCTTTGTACGATGCCACATACGAAACAAAAGAGT CTAAGAAAGAAGACCTAGTATTTATATTCTGGGCTCCTGAAAGTGCACCTTTAAAAAGCAAGATGATTTA TGCTAGCTCTAAAGATGCCATTAAAAAGAAATTTACAGGTATTAAACATGAGTGGCAAGTAAATGGCTTG GATGATATTAAGGACCGTTCGACACTTGGAGAGAAATTGGGAGGCAATGTAGTAGTTTCACTTGAAGGAA AACCATTATAA >OriGene 5' read for NM_138638 unedited
AAAACCCCCGCCCGTTGCCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAG CAGAGCTCAGTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGC GAATTCGGCACGAGGCCGCCACCTCCCTCGGGCTGCAGCTCCCGGCGTGCCCCGCACTCT CCGCTGCCCACCCGCTCGCCCGCCCCTCCTTCTCCTCCCAGTGCCACAGAGCCGAAGCCC GAGCTGCCGCCGCAGCCACAGCCGAGGGCACTATGGCTTCTGGAGTTACAGTGAATGATG AAGTCATCAAAGTTTTTAATGATATGAAAGTAAGGAAATCTTCTACACAAGAGGAGATCA AAAAGAGAAAGAAAGCAGTTCTCTTCTGTTTAAGCGATGACAAAAGACAAATAATTGTAG AGGAAGCAAAGCAGATCTTGGTGGGTGACATTGGTGATACTGTAGAGGACCCCTACACAT CTTTTGTGAAGTTGCTACCTCTGAATGATTGCCGATATGCTTTGTACGATGCCACATACG AAACAAAAGAGTCTAAGAAAGAAGACCTAGTATTTATATTCTGGGCTCCTGAAAGTGCAC CTTTAAAAAGCAAGATGATTTATGCTAGCTCTAAAGATGCCATTAAAAAGAAATTTACAG GTATTAAACATGAGTGGCAAGTAAATGGCTTGGATGATATTAAGGACCGTTCGACACTTG GAGAGAAATTGGGAGGCAATGTAGTAGTTTCACTTGAAGGAAAACCATTATAAAATGACA GTCAAGTGCCATCTGGATCTTAAGGAGCTTNCATTTCTCCAGCTCAGTCCATTGGAAATA GTATAGGGNTTTGGTTATATGATGGATTACCCCCTTTCACTGGGCCCTCCCACACATGAA TGCAGGAGAATCATTATTTAGCGCCTATCAGTGACTGCATTAACTGT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_138638 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_138638.1, NP_619579.1 |
| RefSeq Size | 3093 bp |
| RefSeq ORF | 501 bp |
| Locus ID | 1073 |
| UniProt ID | Q9Y281 |
| Protein Families | Druggable Genome |
| Protein Pathways | Axon guidance, Fc gamma R-mediated phagocytosis, Regulation of actin cytoskeleton |
| Gene Summary | This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009] Transcript Variant: This variant (2) encodes the longer isoform (1). Both variants 1 and 2 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222215 | CFL2 (Myc-DDK-tagged)-Human cofilin 2 (muscle) (CFL2), transcript variant 2 |
CNY 1,200.00 |
|
| RC222215L3 | Lenti ORF clone of Human cofilin 2 (muscle) (CFL2), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC222215L4 | Lenti ORF clone of Human cofilin 2 (muscle) (CFL2), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG222215 | CFL2 (tGFP-tagged) - Human cofilin 2 (muscle) (CFL2), transcript variant 2 |
CNY 2,800.00 |
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