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LRRC8C (NM_032270) Human Untagged Clone
CAT＃: SC105781
LRRC8C (untagged)-Human leucine rich repeat containing 8 family, member C (LRRC8C)
CNY 5,888.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AD158; FAD158 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC105781 sequence for NM_032270 edited (data generated by NextGen Sequencing)
ATGATTCCCGTGACAGAATTCCGGCAGTTCTCTGAGCAGCAGCCTGCCTTCCGAGTGCTG AAGCCATGGTGGGATGTGTTTACCGATTACCTCTCAGTAGCCATGCTCATGATCGGCGTG TTTGGATGTACTTTACAGGTCATGCAAGACAAGATAATCTGCCTTCCGAAAAGAGTGCAG CCTGCTCAGAACCACTCTTCCCTTTCGAATGTCTCTCAAGCAGTTGCCAGTACCACTCCA CTGCCTCCACCTAAACCATCTCCTGCTAACCCCATCACTGTGGAAATGAAAGGCCTGAAG ACAGATTTGGACCTTCAGCAGTACAGCTTTATAAATCAGATGTGTTATGAGCGAGCCCTC CACTGGTATGCCAAGTATTTCCCTTACCTTGTCCTCATCCATACCCTGGTCTTTATGCTC TGCAGTAACTTTTGGTTCAAATTCCCTGGTTCCAGCTCCAAAATAGAACATTTCATCTCC ATTCTGGGGAAGTGTTTTGACTCTCCTTGGACCACACGGGCTTTATCTGAAGTGTCTGGG GAGGACTCAGAAGAAAAGGACAACAGGAAGAACAACATGAACAGGTCCAACACCATCCAA TCTGGTCCAGAAGGCAGCCTGGTCAACTCTCAGTCTTTAAAGTCCATTCCTGAGAAGTTT GTAGTTGATAAATCCACTGCAGGGGCTCTGGATAAAAAGGAAGGTGAGCAGGCTAAGGCC TTATTTGAGAAGGTGAAGAAGTTCAGGCTGCATGTGGAAGAAGGTGATATTCTATATGCC ATGTATGTTCGCCAGACTGTACTTAAAGTTATCAAATTCCTAATCATCATTGCATATAAT AGTGCTCTGGTTTCCAAGGTCCAGTTTACAGTGGACTGTAATGTGGACATTCAGGACATG ACTGGATATAAAAACTTTTCTTGCAATCATACCATGGCACACTTGTTCTCAAAACTGTCC TTTTGCTATCTGTGCTTTGTTAGTATCTATGGATTGACGTGCCTTTATACCTTATACTGG CTGTTCTACCGTTCTCTACGGGAATATTCCTTTGAGTATGTCCGTCAGGAGACTGGAATT GATGATATTCCAGATGTGAAAAATGACTTTGCTTTTATGCTTCATATGATAGATCAGTAT GACCCTCTCTATTCCAAGAGATTTGCAGTGTTCCTGTCTGAAGTCAGTGAAAACAAATTA AAGCAGCTGAACTTAAATAACGAATGGACTCCTGATAAACTGAGGCAGAAGCTACAGACA AATGCCCATAATCGACTGGAATTGCCTCTTATCATGCTCTCTGGCCTTCCAGACACTGTT TTTGAAATCACAGAGTTGCAATCTCTAAAACTTGAAATCATTAAGAACGTAATGATACCA GCCACCATTGCACAGCTAGACAATCTTCAAGAGCTCTCTCTGCACCAGTGTTCTGTCAAA ATCCACAGTGCGGCGCTCTCTTTCCTGAAGGAAAACCTCAAGGTCTTGAGCGTCAAGTTT GATGACATGAGGGAACTCCCCCCCTGGATGTATGGGCTCCGAAATCTGGAAGAGCTGTAC CTAGTTGGCTCTCTAAGTCATGATATTTCCAGAAATGTCACCCTTGAGTCTCTGCGGGAT CTCAAAAGCCTTAAAATTCTCTCTATCAAAAGCAACGTTTCCAAAATCCCTCAGGCAGTG GTTGATGTTTCCAGCCATCTCCAGAAGATGTGCATACATAATGATGGCACCAAGCTGGTG ATGCTCAACAACTTAAAGAAGATGACCAATCTGACAGAGCTGGAGCTGGTCCACTGTGAC CTGGAGCGTATTCCTCATGCTGTGTTCAGCCTACTCAGCCTCCAGGAATTGGACCTGAAG GAAAACAATCTGAAATCTATAGAAGAAATCGTTAGCTTTCAGCACTTAAGAAAGTTGACA GTGCTAAAACTGTGGCATAACAGCATCACCTACATCCCAGAGCATATAAAGAAACTCACC AGCCTGGAACGCCTGTCCTTTAGTCACAATAAAATAGAGGTGCTGCCTTCCCACCTCTTC CTATGCAACAAGATCCGATACTTGGACTTATCGTACAATGACATTCGATTTATCCCCCCT GAAATTGGAGTTCTACAAAGTTTACAGTATTTTTCCATCACATGTAACAAAGTGGAAAGC CTTCCAGATGAACTCTACTTCTGCAAGAAACTTAAAACTCTGAAGATTGGAAAAAACAGC CTATCTGTACTTTCACCGAAAATTGGAAATTTGCTATTTCTTTCCTACTTAGATGTAAAA GGTAATCACTTTGAAATCCTCCCTCCTGAACTGGGTGACTGTCGGGCTCTGAAGCGAGCT GGTTTAGTTGTAGAAGATGCTCTGTTTGAAACTCTGCCTTCTGACGTCCGGGAGCAAATG AAAACAGAATAA Clone variation with respect to NM_032270.4 >OriGene 5' read for NM_032270 unedited
TAAGTTCAGATTTGTATACGACTCATATAGGCGGCCGCGAATTCGCACGAGGGCTTGCGG GGCTGGGGCGTTAGCTGCGTCCCGGCTGGAAGCCCGCGAAGAGAAGTAGGAGGAAGGCGC CGCCGTGGCCGCGGCCGCAGTGCTCGGGCGCGACAAGCCATGAGCAGCGACCCCGCGGGC GACGCCGCCGTCCCTGGCAGCCGCTGAGCCCGACCCCCAGGCAGCTCGCCGCTCCCTAGC ACCTTCTCCAGTCGACACTCTCGCGCCCGGAGAAACATGATTCCCGTGACAGAATTCCGG CAGTTCTCTGAGCAGCAGCCTGCCTTCCGAGTGCTGAAGCCATGGTGGGATGTGTTTACC GATTACCTCTCAGTAGCCATGCTCATGATCGGCGTGTTTGGATGTACTTTACAGGTCATG CAAGACAAGATAATCTGCCTTCCGAAAAGAGTGCAGCCTGCTCAGAACCACTCTTCCCTT TCGAATGTCTCTCAAGCAGTTGCCAGTACCACTCCACTGCCTCCACCTAAACCATCTCCT GCTAACCCCATCACTGTGGAAATGAAAGGCCTGAAGACAGATTTGGACCTTCAGCAGTAC AGCTTTATAAATCAGATGTGTTATGAGCGAGCCCTCCACTGGTATGCCAAGTATTTCCCT TACCTTGTCCTCATCCATACCCTGGTCTTTATGCTCTGCAGTAACTTTTGGTTCANATTC CCTGGTTCCAGCTCCAAAATAGAACATTTCATCTCCATTCTGGGGAAAGTNNGTTTGACT CTCCTTGGACCACACGGGCTTTATCTGAAGTGTCTGGNGAGGACTCAGAAGAAAGGACAC AGGAAGAACACATGAACGGTCCAACCCATCCATCTGGTCAGAGGCAGCCTGGTCA >OriGene 3' read for NM_032270 unedited
CCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTGAAAAAAACAATTAAAT TTTTATTAAAAATACATACNTCCTTACGCGATCTTTGTGTACATTTTGTGTGAAAAGGAA AAAAAAATAGGAAAGGCATTAAGACTACCTAATTATTTATACTGTATTTGGTAGAAGCGT GTTTCAGTCAAACTTTAACGAAAAATAAGTTATTCTGTTTTCATTTGCTCCCGGACGTCA GAAGGCAGAGTTTCAAACAGAGCATCTTCTACAACTAAACCAGCTCGCTTCAGAGCCCGA CAGTCACCCAGTTCAGGAGGGAGGATTTCAAAGTGATTACCTTTTACATCTAAGTAGGAA AGAAATAGCAAATTTCCAATTTTCGGTGAAAGTACAGATAGGCTGTTTTTTCCAATCTTC AGAGTTTTAAGTTTCTTGCAGAAGTAGAGTTCATCTGGAAGGCTTTCCACTTTGTTACAT GTGATGGAAAAATACTGTAAACTTTGTAGAACTCCAATTTCAGGGGGGATAAATCGAATG TCATTGTACGATAAGTCCAAGTATCGGATCTTGTTGCATAGGAAGAGGTGGGAAGGCAGC ACCTCTATTTTATTGTGACTAAAGGACAGGCGTTCCAGGCTGGTGAGTTTCTTTATATGC TCTGGGATGTANGTGATGCTGTTATGCCACAGTTNTAGCACTGTCAACTTTCTTAAGTGC TGAAAGCTAACGATTTCTTCTATAGATTTCAGATTGGTTTCCTTCAGGTCCCATTCCTGG AGGCTGAGTANGCTGAACACAGCATGAGGGATACGCTNCAGNTCACAGTGGNACAGCTNC AGCTCTGTCAGATGGNTCATCTTCTTTTAGNNTGTGAGCATNACAGACTTGGNTGCCATC ATTATGTATGCACATCTTCTGGGAAATGGNCTGAAACATTCCCCACTGGNCTGAGGATTN TGGNAAACNNTGCTTTGATNNAGAGAATTTTAGGCTTTTTGAAATCCGACAGACCTCAGG GGGGAACTTCTGGGATATATGATCTAAAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_032270 |
| Insert Size | 2620 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_032270.2, NP_115646.2 |
| RefSeq Size | 2575 bp |
| RefSeq ORF | 2412 bp |
| Locus ID | 84230 |
| UniProt ID | Q8TDW0 |
| Domains | LRR, LRR_TYP, LRR_PS |
| Protein Families | Transmembrane |
| Gene Summary | Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine. Plays a redundant role in the efflux of amino acids, such as aspartate and glutamate, in response to osmotic stress. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222603 | LRRC8C (Myc-DDK-tagged)-Human leucine rich repeat containing 8 family, member C (LRRC8C) |
CNY 5,880.00 |
|
| RC222603L1 | Lenti ORF clone of Human leucine rich repeat containing 8 family, member C (LRRC8C), Myc-DDK-tagged |
CNY 8,280.00 |
|
| RC222603L2 | Lenti ORF clone of Human leucine rich repeat containing 8 family, member C (LRRC8C), mGFP tagged |
CNY 7,700.00 |
|
| RC222603L3 | Lenti ORF clone of Human leucine rich repeat containing 8 family, member C (LRRC8C), Myc-DDK-tagged |
CNY 8,280.00 |
|
| RC222603L4 | Lenti ORF clone of Human leucine rich repeat containing 8 family, member C (LRRC8C), mGFP tagged |
CNY 8,280.00 |
|
| RG222603 | LRRC8C (tGFP-tagged) - Human leucine rich repeat containing 8 family, member C (LRRC8C) |
CNY 6,370.00 |
