Prolactin Receptor (PRLR) (AF493068) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	HPRL; hPRLrI; MFAB
Vector	pCMV6-XL4
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for AF493068, the custom clone sequence may differ by one or more nucleotides ATGCATGAATGTCCAGACTACATAACCGGTGGCCCCAACTCCTGCCACTTTGGCAAGCAGTACACCTCCA TGTGGAGGACATACATCATGATGGTCAATGCCACTAACCAGATGGGAAGCAGTTTCTCGGATGAACTTTA TGTGGACGTGACTTACATAGTTCAGCCAGACCCTCCTTTGGAGCTGGCTGTGGAAGTAAAACAGCCAGAA GACAGAAAACCCTACCTGTGGATTAAATGGTCTCCACCTACCCTGATTGACTTAAAAACTGGTTGGTTCA CGCTCCTGTATGAAATTCGATTAAAACCCGAGAAAGCAGCTGAGTGGGAGATCCATTTTGCTGGGCAGCA AACAGAGTTTAAGATTCTCAGCCTACATCCAGGACAGAAATACCTTGTCCAGGTTCGCTGCAAACCAGAC CATGGATACTGGAGTGCATGGAGTCCAGCGACCTTCATTCAGATACCTAGTGGTGACCCCTTGATGTTGG GTGCCTCTCATTACAAAAATCTCAAATCTTACAGACCAAGAAAAATCTCAAGTCAAGGAAGACTTGCGGT GTTCACAAAGGCAACATTGACCACAGTCCAGTAG 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for AF493068 unedited NGGTAACCGTTCATAATTTGTCATACGACTCACTATAGGGCGGCCGCGAATTCGCACCAG GGGGACCGGGGAGCGGAGGCTGAAATCCCCANACGCCGGTTTTCTGGGCTGGGCTTTCTG CCTTACTCACTCCTTCTCCCTCTTTCTGGATTTTACCGACCGTTCGCGAAACAGCTTTCC ACACAATGGAGCTTCATGTCCTCGTGCAGGAAGTACTCATCGACTGATGTGGCAGACTTT GCTCCCTGGCAAAACTAAAGAACTCTCCTATTCATGGAGGCGAACACTGAGGATGCTTTC CACATGAACCCTGAAGTGAACTTCTGATACATTTCCTGCAGCAAGAGAAGGCAGCCAACA TGAAGGAAAATGTGGCATCTGCAACCGTTTTCACTCTGCTACTTTTTCTCAACACCTGCC TTCTGAATGGACAGTTACCTCCTGGAAAACCTGAGATCTTTAAATGTCGTTCTCCCAATA AGGAAACATTCACCTGCTGGTGGAGGCCTGGGACAGATGGAGGACTTCCTACCAATTATT CACTGACTTACCACAGGGAAGGAGAGACACTCATGCATGAATGTCCAGACTACATAACCG GTGGCCCCAACTCCTGCCACTTTGGCAAGCAGTACACCTCCATGTGGAGGACATACATCA TGATGGTCAATGCCACTAACCAGATGGGAAGCAGTTTCTCGGATGAACTTTATGNTGGAC GTGACTTACATAGTTCAGCCAGACCCTCCTTTGGAGCTGGCTGTGGAAATAAAACAGCCA GAAGACAGGAAACCCTACCTGTGGATTAAATGGTCTCCACCTACCCTGATTGACTTAAAA ACTGGTTGGGTCACGCTCCTGTATGAAATTCGATTTAAAACCGGAGAAAGCGCT
Restriction Sites	NotI-NotI
ACCN	AF493068
Insert Size	2500 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	AF493068.1, AAM11660.1
RefSeq Size	1206 bp
RefSeq ORF	1206 bp
Locus ID	5618
Domains	FN3
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Neuroactive ligand-receptor interaction
Gene Summary	This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.